Endogenous Sterol Metabolites Regulate Growth of EGFR/KRAS-Dependent Tumors via LXR

Cell Reports

Volumn 12, Issue 11, 2015, Pages 1927-1938

  Gabitova, Linara ^a,d   Restifo, Diana ^a   Gorin, Andrey ^a,d   Manocha, Kunal ^a   Handorf, Elizabeth ^a   Yang, Dong Hua ^a   Cai, Kathy Q ^a   Klein Szanto, Andres J ^a   Cunningham, David ^b   Kratz, Lisa E ^c   Herman, Gail E ^b   Golemis, Erica A ^a   Astsaturov, Igor ^a,d  

^a FOX CHASE CANCER CENTER   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

^d KAZAN FEDERAL UNIVERSITY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER A1; ABC TRANSPORTER G1; CARRIER PROTEINS AND BINDING PROTEINS; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; K RAS PROTEIN; LIVER X RECEPTOR; LIVER X RECEPTOR ALPHA; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PROTEIN NSDHL; PROTEIN SC4MOL; STEROL; UNCLASSIFIED DRUG; 3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; CHOLESTEROL; NR1H3 PROTEIN, HUMAN; NR1H3 PROTEIN, MOUSE; ORPHAN NUCLEAR RECEPTOR; PROTEIN P21;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CANCER CELL; CELL KILLING; CONTROLLED STUDY; DRUG SENSITIVITY; FEMALE; IN VIVO STUDY; KERATINOCYTE; LIPID HOMEOSTASIS; MALE; METABOLITE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SKIN TUMOR; TUMOR GROWTH; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; GENETIC TRANSFECTION; GENETICS; HUMAN; KNOCKOUT MOUSE; METABOLISM; PAPILLOMA; PATHOLOGY; TUMOR CELL LINE;

3-HYDROXYSTEROID DEHYDROGENASES; ANIMALS; CELL LINE, TUMOR; CHOLESTEROL; FEMALE; HUMANS; LIVER X RECEPTORS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; ORPHAN NUCLEAR RECEPTORS; PAPILLOMA; PROTO-ONCOGENE PROTEINS P21(RAS); RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; SKIN NEOPLASMS; STEROLS; TRANSFECTION;

EID: 84942821941     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.08.023     Document Type: Article

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