-
1
-
-
84863627544
-
Protein translocation as a tool: the current rapamycin story
-
Putyrski M., Schultz C. Protein translocation as a tool: the current rapamycin story. FEBS Lett 2012, 586:2097-2105.
-
(2012)
FEBS Lett
, vol.586
, pp. 2097-2105
-
-
Putyrski, M.1
Schultz, C.2
-
2
-
-
77953299013
-
Chemically controlled protein assembly: techniques and applications
-
Fegan A., White B., Carlson J.C., Wagner C.R. Chemically controlled protein assembly: techniques and applications. Chem Rev 2010, 110:3315-3336.
-
(2010)
Chem Rev
, vol.110
, pp. 3315-3336
-
-
Fegan, A.1
White, B.2
Carlson, J.C.3
Wagner, C.R.4
-
3
-
-
79851502862
-
Light regulation of protein dimerization and kinase activity in living cells using photocaged rapamycin and engineered FKBP
-
Karginov A.V., Zou Y., Shirvanyants D., Kota P., Dokholyan N.V., Young D.D., Hahn K.M., Deiters A. Light regulation of protein dimerization and kinase activity in living cells using photocaged rapamycin and engineered FKBP. J Am Chem Soc 2011, 133:420-423.
-
(2011)
J Am Chem Soc
, vol.133
, pp. 420-423
-
-
Karginov, A.V.1
Zou, Y.2
Shirvanyants, D.3
Kota, P.4
Dokholyan, N.V.5
Young, D.D.6
Hahn, K.M.7
Deiters, A.8
-
4
-
-
77954519891
-
Engineered allosteric activation of kinases in living cells
-
Karginov A.V., Ding F., Kota P., Dokholyan N.V., Hahn K.M. Engineered allosteric activation of kinases in living cells. Nat Biotechnol 2010, 28:743-747.
-
(2010)
Nat Biotechnol
, vol.28
, pp. 743-747
-
-
Karginov, A.V.1
Ding, F.2
Kota, P.3
Dokholyan, N.V.4
Hahn, K.M.5
-
5
-
-
78650992316
-
A photocleavable rapamycin conjugate for spatiotemporal control of small GTPase activity
-
Umeda N., Ueno T., Pohlmeyer C., Nagano T., Inoue T. A photocleavable rapamycin conjugate for spatiotemporal control of small GTPase activity. J Am Chem Soc 2011, 133:12-14.
-
(2011)
J Am Chem Soc
, vol.133
, pp. 12-14
-
-
Umeda, N.1
Ueno, T.2
Pohlmeyer, C.3
Nagano, T.4
Inoue, T.5
-
6
-
-
84920784708
-
Light control of cellular processes by using photocaged abscisic acid
-
Wright C.W., Guo Z.F., Liang F.S. Light control of cellular processes by using photocaged abscisic acid. Chembiochem 2015, 16:254-261.
-
(2015)
Chembiochem
, vol.16
, pp. 254-261
-
-
Wright, C.W.1
Guo, Z.F.2
Liang, F.S.3
-
8
-
-
84923077500
-
Light-induced protein dimerization by one- and two-photon activation of gibberellic acid derivatives in living cells
-
Schelkle K.M., Griesbaum T., Ollech D., Becht S., Buckup T., Hamburger M., Wombacher R. Light-induced protein dimerization by one- and two-photon activation of gibberellic acid derivatives in living cells. Angew Chem Int Ed Engl 2015, 54:2825-2829.
-
(2015)
Angew Chem Int Ed Engl
, vol.54
, pp. 2825-2829
-
-
Schelkle, K.M.1
Griesbaum, T.2
Ollech, D.3
Becht, S.4
Buckup, T.5
Hamburger, M.6
Wombacher, R.7
-
9
-
-
84923270836
-
Localized light-induced protein dimerization in living cells using a photocaged dimerizer
-
Ballister E.R., Aonbangkhen C., Mayo A.M., Lampson M.A., Chenoweth D.M. Localized light-induced protein dimerization in living cells using a photocaged dimerizer. Nat Commun 2014, 5:5475.
-
(2014)
Nat Commun
, vol.5
, pp. 5475
-
-
Ballister, E.R.1
Aonbangkhen, C.2
Mayo, A.M.3
Lampson, M.A.4
Chenoweth, D.M.5
-
10
-
-
84883164534
-
Tandem orthogonal chemically induced dimerization
-
Voss S., Wu Y.W. Tandem orthogonal chemically induced dimerization. Chembiochem 2013, 14:1525-1527.
-
(2013)
Chembiochem
, vol.14
, pp. 1525-1527
-
-
Voss, S.1
Wu, Y.W.2
-
11
-
-
84899551653
-
Cell-permeant and photocleavable chemical inducer of dimerization
-
Zimmermann M., Cal R., Janett E., Hoffmann V., Bochet C.G., Constable E., Beaufils F., Wymann M.P. Cell-permeant and photocleavable chemical inducer of dimerization. Angew Chem Int Ed Engl 2014, 53:4717-4720.
-
(2014)
Angew Chem Int Ed Engl
, vol.53
, pp. 4717-4720
-
-
Zimmermann, M.1
Cal, R.2
Janett, E.3
Hoffmann, V.4
Bochet, C.G.5
Constable, E.6
Beaufils, F.7
Wymann, M.P.8
-
12
-
-
84903275034
-
A rapidly reversible chemical dimerizer system to study lipid signaling in living cells
-
Feng S., Laketa V., Stein F., Rutkowska A., MacNamara A., Depner S., Klingmuller U., Saez-Rodriguez J., Schultz C. A rapidly reversible chemical dimerizer system to study lipid signaling in living cells. Angew Chem Int Ed Engl 2014, 53:6720-6723.
-
(2014)
Angew Chem Int Ed Engl
, vol.53
, pp. 6720-6723
-
-
Feng, S.1
Laketa, V.2
Stein, F.3
Rutkowska, A.4
MacNamara, A.5
Depner, S.6
Klingmuller, U.7
Saez-Rodriguez, J.8
Schultz, C.9
-
13
-
-
84925389132
-
A bioorthogonal small-molecule-switch system for controlling protein function in live cells
-
Liu P., Calderon A., Konstantinidis G., Hou J., Voss S., Chen X., Li F., Banerjee S., Hoffmann J.E., Theiss C., et al. A bioorthogonal small-molecule-switch system for controlling protein function in live cells. Angew Chem Int Ed Engl 2014, 53:10049-10055.
-
(2014)
Angew Chem Int Ed Engl
, vol.53
, pp. 10049-10055
-
-
Liu, P.1
Calderon, A.2
Konstantinidis, G.3
Hou, J.4
Voss, S.5
Chen, X.6
Li, F.7
Banerjee, S.8
Hoffmann, J.E.9
Theiss, C.10
-
14
-
-
84878915820
-
Rapidly reversible manipulation of molecular activity with dual chemical dimerizers
-
Lin Y.C., Nihongaki Y., Liu T.Y., Razavi S., Sato M., Inoue T. Rapidly reversible manipulation of molecular activity with dual chemical dimerizers. Angew Chem Int Ed Engl 2013, 52:6450-6454.
-
(2013)
Angew Chem Int Ed Engl
, vol.52
, pp. 6450-6454
-
-
Lin, Y.C.1
Nihongaki, Y.2
Liu, T.Y.3
Razavi, S.4
Sato, M.5
Inoue, T.6
-
15
-
-
53549131018
-
Conditional glycosylation in eukaryotic cells using a biocompatible chemical inducer of dimerization
-
Czlapinski J.L., Schelle M.W., Miller L.W., Laughlin S.T., Kohler J.J., Cornish V.W., Bertozzi C.R. Conditional glycosylation in eukaryotic cells using a biocompatible chemical inducer of dimerization. J Am Chem Soc 2008, 130:13186-13187.
-
(2008)
J Am Chem Soc
, vol.130
, pp. 13186-13187
-
-
Czlapinski, J.L.1
Schelle, M.W.2
Miller, L.W.3
Laughlin, S.T.4
Kohler, J.J.5
Cornish, V.W.6
Bertozzi, C.R.7
-
16
-
-
84883271687
-
Synthetic self-localizing ligands that control the spatial location of proteins in living cells
-
Ishida M., Watanabe H., Takigawa K., Kurishita Y., Oki C., Nakamura A., Hamachi I., Tsukiji S. Synthetic self-localizing ligands that control the spatial location of proteins in living cells. J Am Chem Soc 2013, 135:12684-12689.
-
(2013)
J Am Chem Soc
, vol.135
, pp. 12684-12689
-
-
Ishida, M.1
Watanabe, H.2
Takigawa, K.3
Kurishita, Y.4
Oki, C.5
Nakamura, A.6
Hamachi, I.7
Tsukiji, S.8
-
17
-
-
84878881447
-
Manipulating signaling at will: chemically-inducible dimerization (CID) techniques resolve problems in cell biology
-
DeRose R., Miyamoto T., Inoue T. Manipulating signaling at will: chemically-inducible dimerization (CID) techniques resolve problems in cell biology. Pflugers Arch 2013, 465:409-417.
-
(2013)
Pflugers Arch
, vol.465
, pp. 409-417
-
-
DeRose, R.1
Miyamoto, T.2
Inoue, T.3
-
18
-
-
84925436676
-
In vivo regulation of erythropoiesis by chemically inducible dimerization of the erythropoietin receptor intracellular domain
-
Suzuki N., Mukai H.Y., Yamamoto M. In vivo regulation of erythropoiesis by chemically inducible dimerization of the erythropoietin receptor intracellular domain. PLOS ONE 2015, 10:e0119442.
-
(2015)
PLOS ONE
, vol.10
, pp. e0119442
-
-
Suzuki, N.1
Mukai, H.Y.2
Yamamoto, M.3
-
19
-
-
83655193404
-
Triggering actin comets versus membrane ruffles: distinctive effects of phosphoinositides on actin reorganization
-
Ueno T., Falkenburger B.H., Pohlmeyer C., Inoue T. Triggering actin comets versus membrane ruffles: distinctive effects of phosphoinositides on actin reorganization. Sci Signal 2011, 4:ra87.
-
(2011)
Sci Signal
, vol.4
, pp. ra87
-
-
Ueno, T.1
Falkenburger, B.H.2
Pohlmeyer, C.3
Inoue, T.4
-
20
-
-
84930087956
-
Reversible chemical dimerizer-induced recovery of PIP2 levels moves clathrin to the plasma membrane
-
Schifferer M., Feng S., Stein F., Tischer C., Schultz C. Reversible chemical dimerizer-induced recovery of PIP2 levels moves clathrin to the plasma membrane. Bioorg Med Chem 2015, 23:2862-2867.
-
(2015)
Bioorg Med Chem
, vol.23
, pp. 2862-2867
-
-
Schifferer, M.1
Feng, S.2
Stein, F.3
Tischer, C.4
Schultz, C.5
-
21
-
-
52049084405
-
The anchor-away technique: rapid, conditional establishment of yeast mutant phenotypes
-
Haruki H., Nishikawa J., Laemmli U.K. The anchor-away technique: rapid, conditional establishment of yeast mutant phenotypes. Mol Cell 2008, 31:925-932.
-
(2008)
Mol Cell
, vol.31
, pp. 925-932
-
-
Haruki, H.1
Nishikawa, J.2
Laemmli, U.K.3
-
22
-
-
76249107656
-
Rapid inactivation of proteins by rapamycin-induced rerouting to mitochondria
-
Robinson M.S., Sahlender D.A., Foster S.D. Rapid inactivation of proteins by rapamycin-induced rerouting to mitochondria. Dev Cell 2010, 18:324-331.
-
(2010)
Dev Cell
, vol.18
, pp. 324-331
-
-
Robinson, M.S.1
Sahlender, D.A.2
Foster, S.D.3
-
23
-
-
84908315092
-
Genome-wide mapping of yeast RNA polymerase II termination
-
Schaughency P., Merran J., Corden J.L. Genome-wide mapping of yeast RNA polymerase II termination. PLoS Genet 2014, 10:e1004632.
-
(2014)
PLoS Genet
, vol.10
, pp. e1004632
-
-
Schaughency, P.1
Merran, J.2
Corden, J.L.3
-
24
-
-
84928719564
-
Transcription mediated insulation and interference direct gene cluster expression switches
-
Nguyen T., Fischl H., Howe F.S., Woloszczuk R., Serra Barros A., Xu Z., Brown D., Murray S.C., Haenni S., Halstead J.M., et al. Transcription mediated insulation and interference direct gene cluster expression switches. Elife 2014, 3:e03635.
-
(2014)
Elife
, vol.3
, pp. e03635
-
-
Nguyen, T.1
Fischl, H.2
Howe, F.S.3
Woloszczuk, R.4
Serra Barros, A.5
Xu, Z.6
Brown, D.7
Murray, S.C.8
Haenni, S.9
Halstead, J.M.10
-
25
-
-
84925946869
-
Kinetochore-microtubule error correction is driven by differentially regulated interaction modes
-
Kalantzaki M., Kitamura E., Zhang T., Mino A., Novak B., Tanaka T.U. Kinetochore-microtubule error correction is driven by differentially regulated interaction modes. Nat Cell Biol 2015, 17:421-433.
-
(2015)
Nat Cell Biol
, vol.17
, pp. 421-433
-
-
Kalantzaki, M.1
Kitamura, E.2
Zhang, T.3
Mino, A.4
Novak, B.5
Tanaka, T.U.6
-
26
-
-
84937640515
-
The histone chaperones FACT and Spt6 restrict H2A.Z. from intragenic locations
-
Jeronimo C., Watanabe S., Kaplan C.D., Peterson C.L., Robert F. The histone chaperones FACT and Spt6 restrict H2A.Z. from intragenic locations. Mol Cell 2015, 58:1113-1123.
-
(2015)
Mol Cell
, vol.58
, pp. 1113-1123
-
-
Jeronimo, C.1
Watanabe, S.2
Kaplan, C.D.3
Peterson, C.L.4
Robert, F.5
-
27
-
-
84927670497
-
Prolonged starvation drives reversible sequestration of lipid biosynthetic enzymes and organelle reorganization in Saccharomyces cerevisiae
-
Suresh H.G., da Silveira Dos Santos A.X., Kukulski W., Tyedmers J., Riezman H., Bukau B., Mogk A. Prolonged starvation drives reversible sequestration of lipid biosynthetic enzymes and organelle reorganization in Saccharomyces cerevisiae. Mol Biol Cell 2015, 26:1601-1615.
-
(2015)
Mol Biol Cell
, vol.26
, pp. 1601-1615
-
-
Suresh, H.G.1
da Silveira Dos Santos, A.X.2
Kukulski, W.3
Tyedmers, J.4
Riezman, H.5
Bukau, B.6
Mogk, A.7
-
28
-
-
84866282826
-
NEX-TRAP, a novel method for in vivo analysis of nuclear export of proteins
-
Raschbichler V., Lieber D., Bailer S.M. NEX-TRAP, a novel method for in vivo analysis of nuclear export of proteins. Traffic 2012, 13:1326-1334.
-
(2012)
Traffic
, vol.13
, pp. 1326-1334
-
-
Raschbichler, V.1
Lieber, D.2
Bailer, S.M.3
-
29
-
-
84878628957
-
Specific removal of TACC3-ch-TOG-clathrin at metaphase deregulates kinetochore fiber tension
-
Cheeseman L.P., Harry E.F., McAinsh A.D., Prior I.A., Royle S.J. Specific removal of TACC3-ch-TOG-clathrin at metaphase deregulates kinetochore fiber tension. J Cell Sci 2013, 126:2102-2113.
-
(2013)
J Cell Sci
, vol.126
, pp. 2102-2113
-
-
Cheeseman, L.P.1
Harry, E.F.2
McAinsh, A.D.3
Prior, I.A.4
Royle, S.J.5
-
30
-
-
84866739812
-
Distinct and overlapping roles for AP-1 and GGAs revealed by the 'knocksideways' system
-
Hirst J., Borner G.H., Antrobus R., Peden A.A., Hodson N.A., Sahlender D.A., Robinson M.S. Distinct and overlapping roles for AP-1 and GGAs revealed by the 'knocksideways' system. Curr Biol 2012, 22:1711-1716.
-
(2012)
Curr Biol
, vol.22
, pp. 1711-1716
-
-
Hirst, J.1
Borner, G.H.2
Antrobus, R.3
Peden, A.A.4
Hodson, N.A.5
Sahlender, D.A.6
Robinson, M.S.7
-
31
-
-
84906679884
-
Engineered kinase activation reveals unique morphodynamic phenotypes and associated trafficking for Src family isoforms
-
Chu P.H., Tsygankov D., Berginski M.E., Dagliyan O., Gomez S.M., Elston T.C., Karginov A.V., Hahn K.M. Engineered kinase activation reveals unique morphodynamic phenotypes and associated trafficking for Src family isoforms. Proc Natl Acad Sci U S A 2014, 111:12420-12425.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 12420-12425
-
-
Chu, P.H.1
Tsygankov, D.2
Berginski, M.E.3
Dagliyan, O.4
Gomez, S.M.5
Elston, T.C.6
Karginov, A.V.7
Hahn, K.M.8
-
32
-
-
84897021544
-
Dissecting motility signaling through activation of specific Src-effector complexes
-
Karginov A.V., Tsygankov D., Berginski M., Chu P.H., Trudeau E.D., Yi J.J., Gomez S., Elston T.C., Hahn K.M. Dissecting motility signaling through activation of specific Src-effector complexes. Nat Chem Biol 2014, 10:286-290.
-
(2014)
Nat Chem Biol
, vol.10
, pp. 286-290
-
-
Karginov, A.V.1
Tsygankov, D.2
Berginski, M.3
Chu, P.H.4
Trudeau, E.D.5
Yi, J.J.6
Gomez, S.7
Elston, T.C.8
Hahn, K.M.9
-
33
-
-
84896295429
-
Ligand-gated split-kinases
-
Camacho-Soto K., Castillo-Montoya J., Tye B., Ghosh I. Ligand-gated split-kinases. J Am Chem Soc 2014, 136:3995-4002.
-
(2014)
J Am Chem Soc
, vol.136
, pp. 3995-4002
-
-
Camacho-Soto, K.1
Castillo-Montoya, J.2
Tye, B.3
Ghosh, I.4
-
34
-
-
0037036791
-
Protein splicing triggered by a small molecule
-
Mootz H.D., Muir T.W. Protein splicing triggered by a small molecule. J Am Chem Soc 2002, 124:9044-9045.
-
(2002)
J Am Chem Soc
, vol.124
, pp. 9044-9045
-
-
Mootz, H.D.1
Muir, T.W.2
-
35
-
-
6044271721
-
Activation of an autoregulated protein kinase by conditional protein splicing
-
Mootz H.D., Blum E.S., Muir T.W. Activation of an autoregulated protein kinase by conditional protein splicing. Angew Chem Int Ed Engl 2004, 43:5189-5192.
-
(2004)
Angew Chem Int Ed Engl
, vol.43
, pp. 5189-5192
-
-
Mootz, H.D.1
Blum, E.S.2
Muir, T.W.3
-
36
-
-
33845723065
-
Post-translational enzyme activation in an animal via optimized conditional protein splicing
-
Schwartz E.C., Saez L., Young M.W., Muir T.W. Post-translational enzyme activation in an animal via optimized conditional protein splicing. Nat Chem Biol 2007, 3:50-54.
-
(2007)
Nat Chem Biol
, vol.3
, pp. 50-54
-
-
Schwartz, E.C.1
Saez, L.2
Young, M.W.3
Muir, T.W.4
-
37
-
-
77958194312
-
Probing intracellular motor protein activity using an inducible cargo trafficking assay
-
Kapitein L.C., Schlager M.A., van der Zwan W.A., Wulf P.S., Keijzer N., Hoogenraad C.C. Probing intracellular motor protein activity using an inducible cargo trafficking assay. Biophys J 2010, 99:2143-2152.
-
(2010)
Biophys J
, vol.99
, pp. 2143-2152
-
-
Kapitein, L.C.1
Schlager, M.A.2
van der Zwan, W.A.3
Wulf, P.S.4
Keijzer, N.5
Hoogenraad, C.C.6
-
38
-
-
84865978266
-
A novel split kinesin assay identifies motor proteins that interact with distinct vesicle populations
-
Jenkins B., Decker H., Bentley M., Luisi J., Banker G. A novel split kinesin assay identifies motor proteins that interact with distinct vesicle populations. J Cell Biol 2012, 198:749-761.
-
(2012)
J Cell Biol
, vol.198
, pp. 749-761
-
-
Jenkins, B.1
Decker, H.2
Bentley, M.3
Luisi, J.4
Banker, G.5
-
39
-
-
84961291854
-
A novel assay reveals preferential binding between Rabs, kinesins, and specific endosomal subpopulations
-
Bentley M., Decker H., Luisi J., Banker G. A novel assay reveals preferential binding between Rabs, kinesins, and specific endosomal subpopulations. J Cell Biol 2015, 208:273-281.
-
(2015)
J Cell Biol
, vol.208
, pp. 273-281
-
-
Bentley, M.1
Decker, H.2
Luisi, J.3
Banker, G.4
-
40
-
-
84929584650
-
Optogenetic control of organelle transport using a photocaged chemical inducer of dimerization
-
Ballister E.R., Ayloo S., Chenoweth D.M., Lampson M.A., Holzbaur E.L. Optogenetic control of organelle transport using a photocaged chemical inducer of dimerization. Curr Biol 2015, 25:R407-R408.
-
(2015)
Curr Biol
, vol.25
, pp. R407-R408
-
-
Ballister, E.R.1
Ayloo, S.2
Chenoweth, D.M.3
Lampson, M.A.4
Holzbaur, E.L.5
-
41
-
-
84928587895
-
Compartmentalized AMPK signaling illuminated by genetically encoded molecular sensors and actuators
-
Miyamoto T., Rho E., Sample V., Akano H., Magari M., Ueno T., Gorshkov K., Chen M., Tokumitsu H., Zhang J., et al. Compartmentalized AMPK signaling illuminated by genetically encoded molecular sensors and actuators. Cell Rep 2015, 11:657-670.
-
(2015)
Cell Rep
, vol.11
, pp. 657-670
-
-
Miyamoto, T.1
Rho, E.2
Sample, V.3
Akano, H.4
Magari, M.5
Ueno, T.6
Gorshkov, K.7
Chen, M.8
Tokumitsu, H.9
Zhang, J.10
-
42
-
-
84890036078
-
Using optogenetics to interrogate the dynamic control of signal transmission by the Ras/Erk module
-
Toettcher J.E., Weiner O.D., Lim W.A. Using optogenetics to interrogate the dynamic control of signal transmission by the Ras/Erk module. Cell 2013, 155:1422-1434.
-
(2013)
Cell
, vol.155
, pp. 1422-1434
-
-
Toettcher, J.E.1
Weiner, O.D.2
Lim, W.A.3
-
43
-
-
84871545844
-
Rapidly relocating molecules between organelles to manipulate small GTPase activity
-
Phua S.C., Pohlmeyer C., Inoue T. Rapidly relocating molecules between organelles to manipulate small GTPase activity. ACS Chem Biol 2012, 7:1950-1955.
-
(2012)
ACS Chem Biol
, vol.7
, pp. 1950-1955
-
-
Phua, S.C.1
Pohlmeyer, C.2
Inoue, T.3
|