Lipopolysaccharide from Rhodobacter sphaeroides Attenuates Microglia-Mediated Inflammation and Phagocytosis and Directs Regulatory T Cell Response

International Journal of Inflammation

Volumn 2015, Issue , 2015, Pages

  Gaikwad, Sagar ^a   Agrawal Rajput, Reena ^a  

^a Indian Institute of Advanced Research   (India)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; BACTERIUM LIPOPOLYSACCHARIDE; CD40 ANTIGEN; CD86 ANTIGEN; CHEMOKINE RECEPTOR CCR5; CYCLOOXYGENASE 2; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; RANTES; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR RELA; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; LYMPHOCYTE PROLIFERATION; MICROGLIA; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; RHODOBACTER SPHAEROIDES; SIGNAL TRANSDUCTION;

EID: 84942758766     PISSN: 20908040     EISSN: 20420099     Source Type: Journal    
DOI: 10.1155/2015/361326     Document Type: Article

References (53)

1. W. Y. Chan, S. Kohsaka, and P. Rezaie, "The origin and cell lineage of microglia: newconcepts," Brain Research Reviews, vol. 53, no. 2, pp. 344-354, 2007.
2. G.D. Kutuzova,R.M.Albrecht, C.M. Erickson, andN.Qureshi, "Diphosphoryl lipid A fromRhodobacter sphaeroides blocks the binding and internalization of lipopolysaccharide inRAW264.7 cells," The Journal of Immunology, vol. 167, no. 1, pp. 482-489, 2001.
3. S. R. Coats, T.-T. T. Pham, B. W. Bainbridge, R. A. Reife, and R. P. Darveau, "MD-2 mediates the ability of tetra-acylated and penta-acylated lipopolysaccharides to antagonize Escherichia coli lipopolysaccharide at the TLR4 signaling complex," Journal of Immunology, vol. 175, no. 7, pp. 4490-4498, 2005.
4. A. Visintin, K. A. Halmen, E. Latz, B. G. Monks, and D. T. Golenbock, "Pharmacological inhibition of endotoxin responses is achieved by targeting the TLR4 coreceptor, MD-2," Journal of Immunology, vol. 175, no. 10, pp. 6465-6472, 2005.
5. S.-I. Saitoh, S.Akashi, T. Yamada et al., "LipidAantagonist, lipid IVa, is distinct fromlipidAin interactionwith Toll-like receptor 4 (TLR4)-MD-2 and ligand-induced TLR4 oligomerization," International Immunology, vol. 16, no. 7, pp. 961-969, 2004.
6. C. Cunningham, "Microglia and neurodegeneration: the role of systemic inflammation," Glia, vol. 61, no. 1, pp. 71-90, 2013.
7. S. Alfonso-Loeches, M. Pascual-Lucas, A. M. Blanco, I. Sanchez-Vera, and C. Guerri, "Pivotal role of TLR4 receptors in alcohol-induced neuroinflammation and brain damage," Journal of Neuroscience, vol. 30, no. 24, pp. 8285-8295, 2010.
8. I. J. Crane, S. McKillop-Smith, C. A. Wallace, G. R. Lamont, and J. V. Forrester, "Expression of the chemokines MIP-1α, MCP-1, and RANTES in experimental autoimmune uveitis," Investigative Ophthalmology and Visual Science, vol. 42, no. 7, pp. 1547-1552, 2001.
9. S. Akira, S. Uematsu, and O. Takeuchi, "Pathogen recognition and innate immunity," Cell, vol. 124, no. 4, pp. 783-801, 2006.
10. S.-C. Tang, J. D. Lathia, P. K. Selvaraj et al., "Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid betapeptide and the membrane lipid peroxidation product 4-hydroxynonenal," Experimental Neurology, vol. 213, no. 1, pp. 114-121, 2008.
11. J.-K. Lee, T. Tran, and M. G. Tansey, "Neuroinflammation in Parkinson's disease," Journal of Neuroimmune Pharmacology, vol. 4, no. 4, pp. 419-429, 2009.
12. S.-C. Tang, T. V. Arumugam, X. Xu et al., "Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits," Proceedings of the National Academy of Sciences of the United States of America, vol. 104, no. 34, pp. 13798-13803, 2007.
13. U. Kilic, E. Kilic, C. M. Matter, C. L. Bassetti, and D. M. Hermann, "TLR-4 deficiency protects against focal cerebral ischemia and axotomy-induced neurodegeneration," Neurobiology of Disease, vol. 31, no. 1, pp. 33-40, 2008.
14. M. Song, J. Jin, J.-E. Lim et al., "TLR4 mutation reduces microglial activation, increases Aβ deposits and exacerbates cognitive deficits in a mouse model of Alzheimer's disease," Journal of Neuroinflammation, vol. 8, article 92, 2011.
15. H. Gonzalez and R. Pacheco, "T-cell-mediated regulation of neuroinflammation involved in neurodegenerative diseases," Journal of Neuroinflammation, vol. 11, article 201, 2014.
16. A. Henn, S. Lund, M. Hedtjärn, A. Schrattenholz, P. Pörzgen, and M. Leist, "The suitability of BV2 cells as alternative model system for primary microglia cultures or for animal experiments examining brain inflammation," Altex, vol. 26, no. 2, pp. 83-94, 2009.
17. W. Strittmatter, J. Weckesser, P. V. Salimath, and C. Galanos, "Nontoxic lipopolysaccharide from Rhodopseudomonas sphaeroides ATCC 17023," Journal of Bacteriology, vol. 155, no. 1, pp. 153-158, 1983.
18. C. K. Glass, K. Saijo, B.Winner,M.C.Marchetto, and F. H. Gage, "Mechanisms underlying inflammation in neurodegeneration," Cell, vol. 140, no. 6, pp. 918-934, 2010.
19. L. C. Green, D. A. Wagner, J. Glogowski, P. L. Skipper, J. S. Wishnok, and S. R. Tannenbaum, "Analysis of nitrate, nitrite, and [15N] nitrate in biological fluids," Analytical Biochemistry, vol. 126, no. 1, pp. 131-138, 1982.
20. Z. Xie, C. J. Smith, and L. J. Van Eldik, "Activated glia induce neuron death via MAP kinase signaling pathways involving JNK and p38," Glia, vol. 45, no. 2, pp. 170-179, 2004.
21. S. Ribes, S. Ebert, D. Czesnik et al., "Toll-like receptor prestimulation increases phagocytosis of Escherichia coli DH5α and Escherichia coli K1 strains by murine microglial cells," Infection and Immunity, vol. 77, no. 1, pp. 557-564, 2009.
22. Z. Xu, C.-X. Huang, Y. Li et al., "Toll-like receptor 4 siRNA attenuates LPS-induced secretion of inflammatory cytokines and chemokines by macrophages," Journal of Infection, vol. 55, no. 1, pp. e1-e9, 2007.
23. G.Murugaiyan, R.Agrawal,G.C.Mishra,D.Mitra, and B. Saha, "Differential CD40/CD40L expression results in counteracting antitumor immune responses," Journal of Immunology, vol. 178, no. 4, pp. 2047-2055, 2007.
24. B. Kaltschmidt, M. Uherek, B. Volk, P. A. Baeuerle, and C. Kaltschmidt, "Transcription factor NF-κB is activated in primary neurons by amyloid β peptides and in neurons surrounding early plaques from patients with Alzheimer disease," Proceedings of the National Academy of Sciences of the United States of America, vol. 94, no. 6, pp. 2642-2647, 1997.
25. X. Zhu, H.-G. Lee, A. K. Raina, G. Perry, and M. A. Smith, "The role of mitogen-activated protein kinase pathways in Alzheimer's disease," NeuroSignals, vol. 11, no. 5, pp. 270-281, 2002.
26. B. Kaminska, "MAPK signalling pathways as molecular targets for anti-inflammatory therapy - from molecular mechanisms to therapeutic benefits," Biochimica et Biophysica Acta - Proteins and Proteomics, vol. 1754, no. 1-2, pp. 253-262, 2005.
27. B. Kaminska, A. Gozdz, M. Zawadzka, A. Ellert-Miklaszewska, and M. Lipko, "MAPK signal transduction underlying brain inflammation and gliosis as therapeutic target," Anatomical Record, vol. 292, no. 12, pp. 1902-1913, 2009.
28. E.Okun, K. J.Griffioen, J. D. Lathia, S.-C. Tang, M. P. Mattson, and T. V. Arumugam, "Toll-like receptors in neurodegeneration," Brain Research Reviews, vol. 59, no. 2, pp. 278-292, 2009.
29. W.Mao, X. Yi, J.Qin, M. Tian, and G. Jin, "CXCL12 inhibits cortical neuron apoptosis by increasing the ratio of Bcl-2/Bax after traumatic brain injury," International Journal of Neuroscience, vol. 124, no. 4, pp. 281-290, 2014.
30. J. J. Neher, U. Neniskyte, J.-W. Zhao, A. Bal-Price, A. M. Tolkovsky, and G. C. Brown, "Inhibition of microglial phagocytosis is sufficient to prevent inflammatory neuronal death," Journal of Immunology, vol. 186, no. 8, pp. 4973-4983, 2011.
31. H. Zhou, B. M. Lapointe, S.R.Clark, L.Zbytnuik, and P.Kubes, "A requirement for microglial TLR4 in leukocyte recruitment into brain in response to lipopolysaccharide," The Journal of Immunology, vol. 177, no. 11, pp. 8103-8110, 2006.
32. J.-P. Louboutin and D. S. Strayer, "Relationship between the chemokine receptor CCR5 and microglia in neurological disorders: consequences of targeting CCR5 on neuroinflammation, neuronal death and regeneration in a model of epilepsy," CNS Neurological Disorders and Drug Targets, vol. 12, no. 6, pp. 815-829, 2013.
33. T. Kobayashi, K. Nakatsuka, M. Shimizu et al., "Ribavirin modulates the conversion of human CD4+ CD25- T cell to CD4+ CD25+ FOXP3+ T cell via suppressing interleukin-10-producing regulatory T cell," Immunology, vol. 137, no. 3, pp. 259-270, 2012.
34. J.D. Fontenot, J. P. Rasmussen, L. M. Williams, J. L. Dooley, A. G. Farr, and A. Y. Rudensky, "Regulatory T cell lineage specification by the forkhead transcription factor Foxp3," Immunity, vol. 22, no. 3, pp. 329-341, 2005.
35. M. M. Tiemessen, A. L. Jagger, H. G. Evans,M. J. C. van Herwijnen, S. John, and L. S. Taams, "CD4+CD25+Foxp3+ regulatory T cells induce alternative activation of human monocytes/macrophages," Proceedings of the National Academy of Sciences of the United States of America, vol. 104, no. 49, pp. 19446-19451, 2007.
36. S. Sakaguchi, M. Ono, R. Setoguchi et al., "Foxp3+CD25+CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease," Immunological Reviews, vol. 212, pp. 8-27, 2006.
37. R. Shechter, O.Miller, G. Yovel et al., "Recruitment of beneficial M2 macrophages to injured spinal cord is orchestrated by remote brain choroid plexus," Immunity, vol. 38, no. 3, pp. 555-569, 2013.
38. S. Gordon and F. O. Martinez, "Alternative activation of macrophages: mechanism and functions," Immunity, vol. 32,no. 5, pp. 593-604, 2010.
39. S.Walter,M. Letiembre, Y. Liu et al., "Role of the toll-like receptor 4 in neuroinflammation in Alzheimer's disease," Cellular Physiology and Biochemistry, vol. 20, no. 6, pp. 947-956, 2007.
40. J. D. Luterman, V. Haroutunian, S. Yemul et al., "Cytokine gene expression as a function of the clinical progression ofAlzheimer disease dementia," Archives of Neurology, vol. 57, no. 8, pp. 1153-1160, 2000.
41. I. Ferrer, R. Blanco, M. Carmona et al., "Active, phosphorylation-dependent mitogen-activated protein kinase (MAPK/ERK), stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK), and p38 kinase expression in Parkinson's disease and Dementia with Lewy bodies," Journal of Neural Transmission, vol. 108, no. 12, pp. 1383-1396, 2001.
42. S. Vallabhapurapu and M. Karin, "Regulation and function of NF-kappaB transcription factors in the immune system," Annual Review of Immunology, vol. 27, pp. 693-733, 2009.
43. S. Ghosh and M. S. Hayden, "New regulators of NF-κB in inflammation," Nature Reviews Immunology, vol. 8, no. 11, pp. 837-848, 2008.
44. K. M. Lucin and T. Wyss-Coray, "Immune activation in brain aging and neurodegeneration: too much or too little?" Neuron, vol. 64, no. 1, pp. 110-122, 2009.
45. M.De Paola, A.Mariani, P. Bigini et al., "Neuroprotective effects of toll-like receptor 4 antagonism in spinal cord cultures and in a mouse model of motor neuron degeneration," Molecular Medicine, vol. 18, no. 6, pp. 971-981, 2012.
46. R. M.McManus, S. C. Higgins, K. H. G.Mills, andM. A. Lynch, "Respiratory infection promotes T cell infiltration and amyloid-β deposition in APP/PS1 mice," Neurobiology of Aging, vol. 35, no. 1, pp. 109-121, 2014.
47. G. Lueg, C. C. Gross, H. Lohmann et al., "Clinical relevance of specific T-cell activation in the blood and cerebrospinal fluid of patients with mild Alzheimer's disease," Neurobiology of Aging, vol. 36, no. 1, pp. 81-89, 2015.
48. A.D. Reynolds, R. Banerjee, J. Liu,H. E.Gendelman, and R. L. Mosley, "Neuroprotective activities of CD4+CD25+ regulatory T cells in an animal model of Parkinson's disease," Journal of Leukocyte Biology, vol. 82, no. 5, pp. 1083-1094, 2007.
49. W.Zhao, D. R. Beers, B. Liao, J. S.Henkel, andS.H.Appel, "Regulatory T lymphocytes from ALS mice suppress microglia and effector T lymphocytes through different cytokine-mediated mechanisms," Neurobiology of Disease, vol. 48, no. 3, pp. 418-428, 2012.
50. L. Xie, G. R. Choudhury, A. Winters, S.-H. Yang, and K. Jin, "Cerebral regulatory T cells restrain microglia/macrophagemediated inflammatory responses via IL-10," European Journal of Immunology, vol. 45, no. 1, pp. 180-191, 2015.
51. J. D. Fontenot, M. A. Gavin, and A. Y. Rudensky, "Foxp3 programs the development and function of CD4+CD25+ regulatory T cells," Nature Immunology, vol. 4, no. 4, pp. 330-336, 2003.
52. A. M. Thornton and E. M. Shevach, "CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production," Journal of Experimental Medicine, vol. 188, no. 2, pp. 287-296, 1998.
53. J. Reddy, Z. Illes, X. Zhang et al., "Myelin proteolipid proteinspecific CD4+CD25+ regulatory cellsmediate genetic resistance to experimental autoimmune encephalomyelitis," Proceedings of the National Academy of Sciences of the United States of America, vol. 101, no. 43, pp. 15434-15439, 2004.