A cell-based model system links chromothripsis with hyperploidy

Molecular Systems Biology

Volumn 11, Issue 9, 2015, Pages

  Mardin, Balca R ^a   Drainas, Alexandros P ^a   Waszak, Sebastian M ^a   Weischenfeldt, Joachim ^a   Isokane, Mayumi ^a   Stütz, Adrian M ^a   Raeder, Benjamin ^a   Efthymiopoulos, Theocharis ^a   Buccitelli, Christopher ^a   Segura Wang, Maia ^a   Northcott, Paul ^b   Pfister, Stefan M ^b   Lichter, Peter ^b   Ellenberg, Jan ^a   Korbel, Jan O ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

chromothripsis; DNA rearrangements; hyperploidy; telomere damage; transformation

Indexed keywords

DNA; TELOMERIC REPEAT BINDING FACTOR 2;

ARTICLE; CELL DIVISION; CHROMOSOME NUMBER; CHROMOSOME REARRANGEMENT; CHROMOTHRIPSIS; CONTROLLED STUDY; GENE EXPRESSION; GENOME; HUMAN; HUMAN CELL; HYPERPLOIDY; IN VITRO STUDY; MEDULLOBLASTOMA; PRIORITY JOURNAL; TELOMERE; ANEUPLOIDY; CELL LINE; CHROMOSOME ABERRATION; COPY NUMBER VARIATION; GENE REARRANGEMENT; GENETICS; GENOMIC INSTABILITY; HUMAN CHROMOSOME; HUMAN GENOME; METABOLISM; NEOPLASM; PATHOLOGY; POLYPLOIDY;

ANEUPLOIDY; CELL DIVISION; CELL LINE; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN; DNA COPY NUMBER VARIATIONS; GENE REARRANGEMENT; GENOME, HUMAN; GENOMIC INSTABILITY; HUMANS; MEDULLOBLASTOMA; NEOPLASMS; POLYPLOIDY; TELOMERE; TELOMERIC REPEAT BINDING PROTEIN 2;

EID: 84942520034     PISSN: None     EISSN: 17444292     Source Type: Journal    
DOI: 10.15252/msb.20156505     Document Type: Article

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