Automatic identification and clustering of chromosome phenotypes in a genome wide RNAi screen by time-lapse imaging

Journal of Structural Biology

Volumn 170, Issue 1, 2010, Pages 1-9

  Walter, Thomas ^a   Held, Michael ^a   Neumann, Beate ^a   Hériché, Jean Karim ^b   Conrad, Christian ^a   Pepperkok, Rainer ^a   Ellenberg, Jan ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

Clustering; High throughput screening; Image processing; Live cell imaging; Machine learning; Mathematical morphology; Pattern recognition; Support vector machines; Time series; Time lapse imaging

Indexed keywords

ARTICLE; CHROMOSOME ANALYSIS; CHROMOSOME IDENTIFICATION; GENE FUNCTION; GENOME ANALYSIS; HIGH THROUGHPUT SCREENING; HUMAN; IMAGE ANALYSIS; IMAGE PROCESSING; MACHINE LEARNING; MATHEMATICAL GENETICS; PHENOTYPE; PRIORITY JOURNAL; RNA INTERFERENCE; SUPPORT VECTOR MACHINE;

ARTIFICIAL INTELLIGENCE; COMPUTATIONAL BIOLOGY; GENE EXPRESSION PROFILING; HELA CELLS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; PHENOTYPE; PROTEOMICS; RNA INTERFERENCE; SOFTWARE; TIME FACTORS;

EID: 77950525573     PISSN: 10478477     EISSN: 10958657     Source Type: Journal    
DOI: 10.1016/j.jsb.2009.10.004     Document Type: Article

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