Female-specific downregulation of tissue polymorphonuclear neutrophils drives impaired regulatory T cell and amplified effector T cell responses in autoimmune dry eye disease

Journal of Immunology

Volumn 195, Issue 7, 2015, Pages 3086-3099

  Gao, Yuan ^a   Min, Kyungji ^a   Zhang, Yibing ^a   Su, John ^a   Greenwood, Matthew ^a   Gronert, Karsten ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; LIPOXIN A; ESTROGEN; LIPOXIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; CELLULAR IMMUNODEFICIENCY; CERVICAL LYMPH NODE; CONTROLLED STUDY; CORNEA LIMBUS; DOWN REGULATION; DRY EYE; EFFECTOR CELL; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; IMMUNOPATHOGENESIS; IMMUNOREGULATION; LACRIMAL GLAND; LYMPHOCYTE COUNT; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; REGULATORY T LYMPHOCYTE; SEX DIFFERENCE; STRESS; T LYMPHOCYTE ACTIVATION; TH1 CELL; TH17 CELL; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; IMMUNOLOGY; LACRIMAL APPARATUS; LYMPH NODE; LYMPHOCYTE ACTIVATION; METABOLISM; PHYSIOLOGY; WOUND HEALING;

ANIMALS; AUTOIMMUNE DISEASES; DOWN-REGULATION; DRY EYE SYNDROMES; ESTROGENS; FEMALE; LACRIMAL APPARATUS; LIMBUS CORNEAE; LIPOXINS; LYMPH NODES; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; MALE; MICE; MICE, INBRED C57BL; NEUTROPHILS; SEX FACTORS; T-LYMPHOCYTES, REGULATORY; TH1 CELLS; TH17 CELLS; WOUND HEALING;

EID: 84942475190     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1500610     Document Type: Article

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