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Volumn 26, Issue 4, 2012, Pages 1506-1516

Estrogen negatively regulates epithelial wound healing and protective lipid mediator circuits in the cornea

Author keywords

15 LOX; 17 estradiol; ER ; ER ; Lipoxin A4; Sex specific

Indexed keywords

ARACHIDONATE 15 LIPOXYGENASE; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; LIPID; LIPOXIN A; MESSENGER RNA;

EID: 84860897888     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-198036     Document Type: Article
Times cited : (85)

References (56)
  • 1
    • 33644638521 scopus 로고    scopus 로고
    • Estrogen receptors and human disease
    • DOI 10.1172/JCI27987
    • Deroo, B. J., and Korach, K. S. (2006) Estrogen receptors and human disease. J. Clin. Invest. 116, 561-570 (Pubitemid 43326860)
    • (2006) Journal of Clinical Investigation , vol.116 , Issue.3 , pp. 561-570
    • Deroo, B.J.1    Korach, K.S.2
  • 2
    • 77952955740 scopus 로고    scopus 로고
    • Sex steroids as inflammatory regulators
    • Gilliver, S. C. (2010) Sex steroids as inflammatory regulators. J. Steroid Biochem. Mol. Biol. 120, 105-115
    • (2010) J. Steroid Biochem. Mol. Biol. , vol.120 , pp. 105-115
    • Gilliver, S.C.1
  • 4
    • 34547792318 scopus 로고    scopus 로고
    • The complex role of estrogens in inflammation
    • Straub, R. H. (2007) The complex role of estrogens in inflammation. Endocr. Rev. 28, 521-574
    • (2007) Endocr. Rev. , vol.28 , pp. 521-574
    • Straub, R.H.1
  • 6
    • 0034035187 scopus 로고    scopus 로고
    • Identification of androgen, estrogen and progesterone receptor mRNAs in the eye
    • DOI 10.1034/j.1600-0420.2000.078002146.x
    • Wickham, L. A., Gao, J., Toda, I., Rocha, E. M., Ono, M., and Sullivan, D. A. (2000) Identification of androgen, estrogen and progesterone receptor mRNAs in the eye. Acta Ophthalmol. Scand. 78, 146-153 (Pubitemid 30201420)
    • (2000) Acta Ophthalmologica Scandinavica , vol.78 , Issue.2 , pp. 146-153
    • Wickham, L.A.1    Gao, J.2    Toda, I.3    Rocha, E.M.4    Ono, M.5    Sullivan, D.A.6
  • 10
    • 77049103147 scopus 로고    scopus 로고
    • Sex and sex steroid influence on dry eye syndromes
    • (Pflugfelder, S., Beuerman, R., and Stern, M. E., eds) Marcel Dekker, New York
    • Sullivan, D. A. (2004) Sex and sex steroid influence on dry eye syndromes. In Dry Eye and Ocular Surface Disease (Pflugfelder, S., Beuerman, R., and Stern, M. E., eds) pp. 165-190, Marcel Dekker, New York
    • (2004) Dry Eye and Ocular Surface Disease , pp. 165-190
    • Sullivan, D.A.1
  • 11
    • 33947537209 scopus 로고    scopus 로고
    • Dry eye syndromes
    • DOI 10.1159/000099268, Immune Response and the Eye
    • Barabino, S., and Dana, M. R. (2007) Dry eye syndromes. Chem. Immunol. Allergy 92, 176-184 (Pubitemid 47096906)
    • (2007) Chemical Immunology and Allergy , vol.92 , pp. 176-184
    • Barabino, S.1    Dana, M.R.2
  • 12
    • 20144365575 scopus 로고    scopus 로고
    • Tearful relationships? Sex, hormones, the lacrimal gland, and aqueous-deficient dry eye
    • Sullivan, D. A. (2004) Tearful relationships? Sex, hormones, the lacrimal gland, and aqueous-deficient dry eye. Ocul. Surf. 2, 92-123
    • (2004) Ocul. Surf. , vol.2 , pp. 92-123
    • Sullivan, D.A.1
  • 14
    • 33745014599 scopus 로고    scopus 로고
    • Comparative effects of estrogen on matrix metalloproteinases and cytokines in immortalized and primary human corneal epithelial cell cultures
    • DOI 10.1097/01.ico.0000220777.70981.46, PII 0000322620060500000015
    • Suzuki, T., and Sullivan, D. A. (2006) Comparative effects of estrogen on matrix metalloproteinases and cytokines in immortalized and primary human corneal epithelial cell cultures. Cornea 25, 454-459 (Pubitemid 44620132)
    • (2006) Cornea , vol.25 , Issue.4 , pp. 454-459
    • Suzuki, T.1    Sullivan, D.A.2
  • 15
    • 28044472795 scopus 로고    scopus 로고
    • Estrogen stimulation of proinflammatory cytokine and matrix metalloproteinase gene expression in human corneal epithelial cells
    • DOI 10.1097/01.ico.0000160973.04072.a5
    • Suzuki, T., and Sullivan, D. A. (2005) Estrogen stimulation of proinflammatory cytokine and matrix metalloproteinase gene expression in human corneal epithelial cells. Cornea 24, 1004-1009 (Pubitemid 41688540)
    • (2005) Cornea , vol.24 , Issue.8 , pp. 1004-1009
    • Suzuki, T.1    Sullivan, D.A.2
  • 17
    • 77950365906 scopus 로고    scopus 로고
    • Nonresolving inflammation
    • Nathan, C., and Ding, A. (2010) Nonresolving inflammation. Cell 140, 871-882
    • (2010) Cell , vol.140 , pp. 871-882
    • Nathan, C.1    Ding, A.2
  • 19
    • 0036779617 scopus 로고    scopus 로고
    • Anti-inflammatory lipid mediators and insights into the resolution of inflammation
    • DOI 10.1038/nri915
    • Lawrence, T., Willoughby, D. A., and Gilroy, D. W. (2002) Anti-inflammatory lipid mediators and insights into the resolution of inflammation. Nat. Rev. Immunology 2, 787-795 (Pubitemid 37328718)
    • (2002) Nature Reviews Immunology , vol.2 , Issue.10 , pp. 787-795
    • Lawrence, T.1    Willoughby, D.A.2    Gilroy, D.W.3
  • 20
    • 78651469994 scopus 로고    scopus 로고
    • Resolution, the grail for healthy ocular inflammation
    • Gronert, K. (2010) Resolution, the grail for healthy ocular inflammation. Exp. Eye Res. 91, 478-485
    • (2010) Exp. Eye Res. , vol.91 , pp. 478-485
    • Gronert, K.1
  • 21
    • 77955872825 scopus 로고    scopus 로고
    • Molecular circuits of resolution in the eye
    • Liclican, E. L., and Gronert, K. (2010) Molecular circuits of resolution in the eye. Sci. World J. 10, 1029-1047
    • (2010) Sci. World J. , vol.10 , pp. 1029-1047
    • Liclican, E.L.1    Gronert, K.2
  • 22
    • 0033693332 scopus 로고    scopus 로고
    • Lipoxins: Novel anti-inflammatory therapeutics?
    • Godson, C., and Brady, H. R. (2000) Lipoxins: Novel anti-inflammatory therapeutics? Curr. Op. Invest. Drugs 1, 380-385
    • (2000) Curr. Op. Invest. Drugs , vol.1 , pp. 380-385
    • Godson, C.1    Brady, H.R.2
  • 25
    • 70350127334 scopus 로고    scopus 로고
    • Lipoxins: Resolutionary road
    • Maderna, P., and Godson, C. (2009) Lipoxins: resolutionary road. Br. J. Pharmacol. 158, 947-959
    • (2009) Br. J. Pharmacol. , vol.158 , pp. 947-959
    • Maderna, P.1    Godson, C.2
  • 26
    • 42649089790 scopus 로고    scopus 로고
    • Resolving inflammation: Dual anti-inflammatory and pro-resolution lipid mediators
    • DOI 10.1038/nri2294, PII NRI2294
    • Serhan, C. N., Chiang, N., and Van Dyke, T. E. (2008) Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators. Nat. Rev. Immunol. 8, 349-361 (Pubitemid 351595216)
    • (2008) Nature Reviews Immunology , vol.8 , Issue.5 , pp. 349-361
    • Serhan, C.N.1    Chiang, N.2    Van Dyke, T.E.3
  • 28
    • 24344510350 scopus 로고    scopus 로고
    • Anti-inflammatory circuitry: Lipoxin, aspirin-triggered lipoxins and their receptor ALX
    • DOI 10.1016/j.plefa.2005.05.003, PII S0952327805000815
    • Chiang, N., Arita, M., and Serhan, C. N. (2005) Anti-inflammatory circuitry: lipoxin, aspirin-triggered lipoxins and their receptor ALX. Prostaglan. Leukot. Essent. Fatty Acids 73, 163-177 (Pubitemid 41253473)
    • (2005) Prostaglandins Leukotrienes and Essential Fatty Acids , vol.73 , Issue.3-4 , pp. 163-177
    • Chiang, N.1    Arita, M.2    Serhan, C.N.3
  • 29
    • 73949160807 scopus 로고    scopus 로고
    • Endogenous LXA4 circuits are determinants of pathological angiogenesis in response to chronic injury
    • Leedom, A. J., Sullivan, A. B., Dong, B., Lau, D., and Gronert, K. (2010) Endogenous LXA4 circuits are determinants of pathological angiogenesis in response to chronic injury. Am. J. Pathol. 176, 74-84
    • (2010) Am. J. Pathol. , vol.176 , pp. 74-84
    • Leedom, A.J.1    Sullivan, A.B.2    Dong, B.3    Lau, D.4    Gronert, K.5
  • 30
    • 34347378262 scopus 로고    scopus 로고
    • 4 and heme-oxygenase in counter-regulating inflammation during corneal wound healing
    • DOI 10.1096/fj.06-7918com
    • Biteman, B., Hassan, I. R., Walker, E., Leedom, A. J., Dunn, M., Seta, F., Laniado-Schwartzman, M., and Gronert, K. (2007) Interdependence of lipoxin A4 and heme-oxygenase in counter-regulating inflammation during corneal wound healing. FASEB J. 21, 2257-2266 (Pubitemid 47026460)
    • (2007) FASEB Journal , vol.21 , Issue.9 , pp. 2257-2266
    • Biteman, B.1    Hassan, I.R.2    Walker, E.3    Leedom, A.J.4    Dunn, M.5    Seta, F.6    Laniado-Schwartzman, M.7    Gronert, K.8
  • 31
    • 17644394983 scopus 로고    scopus 로고
    • A role for the mouse 12/15-lipoxygenase pathway in promoting epithelial wound healing and host defense
    • DOI 10.1074/jbc.M410638200
    • Gronert, K., Maheshwari, N., Khan, N., Hassan, I. R., Dunn, M., and Laniado Schwartzman, M. (2005) A role for the mouse 12/15-lipoxygenase pathway in promoting epithelial wound healing and host defense. J. Biol. Chem. 280, 15267-15278 (Pubitemid 40562883)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.15 , pp. 15267-15278
    • Gronert, K.1    Maheshwari, N.2    Khan, N.3    Hassan, I.R.4    Dunn, M.5    Schwartzman, M.L.6
  • 32
    • 40849085188 scopus 로고    scopus 로고
    • Lipid autacoids in inflammation and injury responses: A matter of privilege
    • Gronert, K. (2008) Lipid autacoids in inflammation and injury responses: a matter of privilege. Mol. Interv. 8, 28-35
    • (2008) Mol. Interv. , vol.8 , pp. 28-35
    • Gronert, K.1
  • 33
    • 24344460574 scopus 로고    scopus 로고
    • Lipoxins in the eye and their role in wound healing
    • Gronert, K. (2005) Lipoxins in the eye and their role in wound healing. Prostaglan. Leukot. Essent. Fatty Acids 73, 221-229
    • (2005) Prostaglan. Leukot. Essent. Fatty Acids , vol.73 , pp. 221-229
    • Gronert, K.1
  • 35
    • 77149156927 scopus 로고    scopus 로고
    • Anti-inflammatory effects of lipoxins on lipopolysaccharide-induced uveitis in rats
    • Karim, M. J., Bhattacherjee, P., Biswas, S., and Paterson, C. A. (2009) Anti-inflammatory effects of lipoxins on lipopolysaccharide-induced uveitis in rats. J. Ocul. Pharmacol. Ther. 25, 483-486
    • (2009) J. Ocul. Pharmacol. Ther. , vol.25 , pp. 483-486
    • Karim, M.J.1    Bhattacherjee, P.2    Biswas, S.3    Paterson, C.A.4
  • 37
    • 67650543847 scopus 로고    scopus 로고
    • Selective survival rescue in 15-lipoxygenase-1 deficient retinal pigment epithelial cells by the novel docosahexaenoic acid-derived mediator, neuroprotectin D1
    • Calandria, J. M., Marcheselli, V. L., Mukherjee, P. K., Uddin, J., Winkler, J. W., Petasis, N. A., and Bazan, N. G. (2009) Selective survival rescue in 15-lipoxygenase-1 deficient retinal pigment epithelial cells by the novel docosahexaenoic acid-derived mediator, neuroprotectin D1. J. Biol. Chem. 284, 17877-17882
    • (2009) J. Biol. Chem. , vol.284 , pp. 17877-17882
    • Calandria, J.M.1    Marcheselli, V.L.2    Mukherjee, P.K.3    Uddin, J.4    Winkler, J.W.5    Petasis, N.A.6    Bazan, N.G.7
  • 38
    • 79960533372 scopus 로고    scopus 로고
    • Docosahexaenoic Acid signalolipidomics in nutrition: Significance in aging, neuroinflammation, macular degeneration, Alzheimer's, and other neurodegenerative diseases
    • Bazan, N. G., Molina, M. F., and Gordon, W. C. (2011) Docosahexaenoic Acid signalolipidomics in nutrition: significance in aging, neuroinflammation, macular degeneration, Alzheimer's, and other neurodegenerative diseases. Annu. Rev. Nutr. 31, 321-351
    • (2011) Annu. Rev. Nutr. , vol.31 , pp. 321-351
    • Bazan, N.G.1    Molina, M.F.2    Gordon, W.C.3
  • 41
    • 79955946574 scopus 로고    scopus 로고
    • Selective activation of the prostaglandin E2 circuit is a key component of chronic injury-induced pathological angiogenesis
    • Liclican, E. L., Nguyen, V., Sullivan, A. B., and Gronert, K. (2010) Selective activation of the prostaglandin E2 circuit is a key component of chronic injury-induced pathological angiogenesis. Invest. Ophthalmol. Vis. Sci. 51, 6311-6320
    • (2010) Invest. Ophthalmol. Vis. Sci. , vol.51 , pp. 6311-6320
    • Liclican, E.L.1    Nguyen, V.2    Sullivan, A.B.3    Gronert, K.4
  • 42
    • 34548854506 scopus 로고    scopus 로고
    • Gammadelta T cells are necessary for platelet and neutrophil accumulation in limbal vessels and efficient epithelial repair after corneal abrasion
    • DOI 10.2353/ajpath.2007.070008
    • Li, Z., Burns, A. R., Rumbaut, R. E., and Smith, C. W. (2007) Gamma delta T cells are necessary for platelet and neutrophil accumulation in limbal vessels and efficient epithelial repair after corneal abrasion. Am. J. Pathol. 171, 838-845 (Pubitemid 47440983)
    • (2007) American Journal of Pathology , vol.171 , Issue.3 , pp. 838-845
    • Li, Z.1    Burns, A.R.2    Rumbaut, R.E.3    Smith, C.W.4
  • 43
    • 34247117785 scopus 로고    scopus 로고
    • Platelet response to corneal abrasion is necessary for acute inflammation and efficient re-epithelialteation
    • DOI 10.1167/iovs.06-0381
    • Li, Z., Rumbaut, R. E., Burns, A. R., and Smith, C. W. (2006) Platelet response to corneal abrasion is necessary for acute inflammation and efficient re-epithelialization. Invest. Ophthalmol. Vis. Sci. 47, 4794-4802 (Pubitemid 46586377)
    • (2006) Investigative Ophthalmology and Visual Science , vol.47 , Issue.11 , pp. 4794-4802
    • Li, Z.1    Rumbaut, R.E.2    Burns, A.R.3    Smith, C.W.4
  • 44
    • 33744746225 scopus 로고    scopus 로고
    • Two waves of neutrophil emigration in response to corneal epithelial abrasion: Distinct adhesion molecule requirements
    • DOI 10.1167/iovs.05-1193
    • Li, Z., Burns, A. R., and Smith, C. W. (2006) Two waves of neutrophil emigration in response to corneal epithelial abrasion: distinct adhesion molecule requirements. Invest. Ophthalmol. Vis. Sci. 47, 1947-1955 (Pubitemid 46768275)
    • (2006) Investigative Ophthalmology and Visual Science , vol.47 , Issue.5 , pp. 1947-1955
    • Li, Z.1    Burns, A.R.2    Smith, C.W.3
  • 46
  • 48
    • 33745051855 scopus 로고    scopus 로고
    • Identification of steroidogenic enzyme mRNAs in the human lacrimal gland, meibomian gland, cornea, and conjunctiva
    • DOI 10.1097/01.ico.0000183664.80004.44, PII 0000322620060500000012
    • Schirra, F., Suzuki, T., Dickinson, D. P., Townsend, D. J., Gipson, I. K., and Sullivan, D. A. (2006) Identification of steroidogenic enzyme mRNAs in the human lacrimal gland, meibomian gland, cornea, and conjunctiva. Cornea 25, 438-442 (Pubitemid 44620129)
    • (2006) Cornea , vol.25 , Issue.4 , pp. 438-442
    • Schirra, F.1    Suzuki, T.2    Dickinson, D.P.3    Townsend, D.J.4    Gipson, I.K.5    Sullivan, D.A.6
  • 49
    • 79956027719 scopus 로고    scopus 로고
    • EGF stimulates lipoxin A4 synthesis and modulates repair in corneal epithelial cells through ERK and p38 activation
    • Kenchegowda, S., Bazan, N. G., and Bazan, H. E. (2011) EGF stimulates lipoxin A4 synthesis and modulates repair in corneal epithelial cells through ERK and p38 activation. Invest. Ophthalmol. Vis. Sci. 52, 2240-2249
    • (2011) Invest. Ophthalmol. Vis. Sci. , vol.52 , pp. 2240-2249
    • Kenchegowda, S.1    Bazan, N.G.2    Bazan, H.E.3
  • 50
    • 14844318039 scopus 로고    scopus 로고
    • Epidermal and hepatocyte growth factors, but not keratinocyte growth factor, modulate protein kinase Cα translocation to the plasma membrane through 15(S)-hydroxyeicosatetraenoic acid synthesis
    • DOI 10.1074/jbc.M408852200
    • Sharma, G. D., Ottino, P., Bazan, N. G., and Bazan, H. E. (2005) Epidermal and hepatocyte growth factors, but not keratinocyte growth factor, modulate protein kinase Cα translocation to the plasma membrane through 15(S)-hydroxyeicosatetraenoic acid synthesis. J. Biol. Chem. 280, 7917-7924 (Pubitemid 40349689)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.9 , pp. 7917-7924
    • Sharma, G.D.1    Ottino, P.2    Bazan, N.G.3    Bagan, H.E.P.4
  • 53
    • 84455170679 scopus 로고    scopus 로고
    • Gender difference in re-epithelialisation time in fungal corneal ulcers
    • [E-pub ahead of print] doi: 10.1136/bjophthalmol-2011-300441
    • Krishnan, T., Pranja, N., Gronert, K., Oldenburg, E., Ray, K., Keenan, J. D., Lietman, T., and Acharya, N. (2011) Gender difference in re-epithelialisation time in fungal corneal ulcers. [E-pub ahead of print] Br. J. Ophthalmol. doi: 10.1136/bjophthalmol-2011-300441
    • (2011) Br. J. Ophthalmol.
    • Krishnan, T.1    Pranja, N.2    Gronert, K.3    Oldenburg, E.4    Ray, K.5    Keenan, J.D.6    Lietman, T.7    Acharya, N.8
  • 54
    • 11144256156 scopus 로고    scopus 로고
    • Lumican regulates corneal inflammatory responses by modulating Fas-Fas ligand signaling
    • DOI 10.1167/iovs.04-0833
    • Vij, N., Roberts, L., Joyce, S., and Chakravarti, S. (2005) Lumican regulates corneal inflammatory responses by modulating Fas-Fas ligand signaling. Investigat. Ophthalmol. Visual. Sci. 46, 88-95 (Pubitemid 40041183)
    • (2005) Investigative Ophthalmology and Visual Science , vol.46 , Issue.1 , pp. 88-95
    • Vij, N.1    Roberts, L.2    Joyce, S.3    Chakravarti, S.4
  • 55
    • 82655181504 scopus 로고    scopus 로고
    • Lipoxin A4 is a novel estrogen receptor modulator
    • [E-pub ahead of print] doi: 10.1096/fj.11-187658
    • Russell, R., Gori, I., Pellegrini, C., Kumar, R., Achtari, C., and Canny, G. O. (2011) Lipoxin A4 is a novel estrogen receptor modulator. [E-pub ahead of print] FASEB J. doi: 10.1096/fj.11-187658
    • (2011) FASEB J.
    • Russell, R.1    Gori, I.2    Pellegrini, C.3    Kumar, R.4    Achtari, C.5    Canny, G.O.6
  • 56
    • 77951070157 scopus 로고    scopus 로고
    • Significance of lipid mediators in corneal injury and repair
    • Kenchegowda, S., and Bazan, H. E. (2010) Significance of lipid mediators in corneal injury and repair. J. Lipid Res. 51, 879-891
    • (2010) J. Lipid Res. , vol.51 , pp. 879-891
    • Kenchegowda, S.1    Bazan, H.E.2


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