Genome Engineering of the 2,3-Butanediol Biosynthetic Pathway for Tight Regulation in Cyanobacteria

ACS Synthetic Biology

Volumn 4, Issue 11, 2015, Pages 1197-1204

  Nozzi, Nicole E ^a   Atsumi, Shota ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

2,3 butanediol; cyanobacteria; lac promoter

Indexed keywords

2,3 BUTANEDIOL; 2,3-BUTYLENE GLYCOL; BUTANEDIOL; GREEN FLUORESCENT PROTEIN;

ARTICLE; GENE EXPRESSION; GENE ORDER; GENETIC ENGINEERING; GENETIC STABILITY; GENOME; NONHUMAN; OPERON; PRIORITY JOURNAL; PROMOTER REGION; SYNECHOCOCCUS ELONGATUS; BACTERIAL GENOME; CYANOBACTERIUM; GAS CHROMATOGRAPHY; GENETICS; METABOLISM; PLASMID; SYNTHETIC BIOLOGY;

BUTYLENE GLYCOLS; CHROMATOGRAPHY, GAS; CYANOBACTERIA; GENETIC ENGINEERING; GENOME, BACTERIAL; GREEN FLUORESCENT PROTEINS; PLASMIDS; SYNTHETIC BIOLOGY;

EID: 84942454433     PISSN: None     EISSN: 21615063     Source Type: Journal    
DOI: 10.1021/acssynbio.5b00057     Document Type: Article

References (36)

1. Witcover, J., Yeh, S., and Sperling, D. (2013) Policy options to address global land use change from biofuels Energy Policy 56, 63-74
2. Machado, I. M. and Atsumi, S. (2012) Cyanobacterial biofuel production J. Biotechnol. 162, 50-56
3. Berla, B. M., Saha, R., Immethun, C. M., Maranas, C. D., Moon, T. S., and Pakrasi, H. B. (2013) Synthetic biology of cyanobacteria: unique challenges and opportunities Front. Microbiol. 4, 246
4. 2 Curr. Opin. Biotechnol. 33, 8-14
5. Hays, S. G. and Ducat, D. C. (2014) Engineering cyanobacteria as photosynthetic feedstock factories Photosynth. Res. 123, 285-295
6. Davies, F. K., Jinkerson, R. E., and Posewitz, M. C. (2014) Toward a photosynthetic microbial platform for terpenoid engineering Photosynth. Res. 123, 265-284
7. Heidorn, T., Camsund, D., Huang, H. H., Lindberg, P., Oliveira, P., Stensjo, K., and Lindblad, P. (2011) Synthetic biology in cyanobacteria engineering and analyzing novel functions Methods Enzymol. 497, 539-579
8. Camsund, D. and Lindblad, P. (2014) Engineered transcriptional systems for cyanobacterial biotechnology Front. Bioeng. Biotechnol. 2, 40
9. Nozzi, N. E., Oliver, J. W. K., and Atsumi, S. (2013) Cyanobacteria as a platform for biofuel production Front. Bioeng. Biotechnol. 1, 7
10. Ducat, D. C., Way, J. C., and Silver, P. A. (2011) Engineering cyanobacteria to generate high-value products Trends Biotechnol. 29, 95-103
11. Markley, A. L., Begemann, M. B., Clarke, R. E., Gordon, G. C., and Pfleger, B. F. (2014) Synthetic biology toolbox for controlling gene expression in the cyanobacterium Synechococcus sp. strain PCC 7002 ACS Synth. Biol. 10.1021/sb500260k
12. Oliver, J. W., Machado, I. M., Yoneda, H., and Atsumi, S. (2014) Combinatorial optimization of cyanobacterial 2,3-butanediol production Metab. Eng. 22, 76-82
13. Oliver, J. W., Machado, I. M., Yoneda, H., and Atsumi, S. (2013) Cyanobacterial conversion of carbon dioxide to 2,3-butanediol Proc. Natl. Acad. Sci. U. S. A. 110, 1249-1254
14. Syu, M. J. (2001) Biological production of 2,3-butanediol Appl. Microbiol. Biotechnol. 55, 10-18
15. Lutz, R. and Bujard, H. (1997) Independent and tight regulation of transcriptional units in Escherichia coli via the LacR/O, the TetR/O and AraC/I1-I2 regulatory elements Nucleic Acids Res. 25, 1203-1210
16. Huang, H. H., Camsund, D., Lindblad, P., and Heidorn, T. (2010) Design and characterization of molecular tools for a Synthetic Biology approach towards developing cyanobacterial biotechnology Nucleic Acids Res. 38, 2577-2593
17. Guerrero, F., Carbonell, V., Cossu, M., Correddu, D., and Jones, P. R. (2012) Ethylene synthesis and regulated expression of recombinant protein in Synechocystis sp. PCC 6803 PLoS One 7, e50470
18. Camsund, D., Heidorn, T., and Lindblad, P. (2014) Design and analysis of LacI-repressed promoters and DNA-looping in a cyanobacterium J. Biol. Eng. 8, 4
19. Atsumi, S., Higashide, W., and Liao, J. C. (2009) Direct photosynthetic recycling of carbon dioxide to isobutyraldehyde Nat. Biotechnol. 27, 1177-1180
20. Jones, P. R. (2014) Genetic instability in cyanobacteria - an elephant in the room? Front. Bioeng. Biotechnol. 2, 12
21. Huang, H. H. and Lindblad, P. (2013) Wide-dynamic-range promoters engineered for cyanobacteria J. Biol. Eng. 7, 10
22. Pedelacq, J. D., Cabantous, S., Tran, T., Terwilliger, T. C., and Waldo, G. S. (2006) Engineering and characterization of a superfolder green fluorescent protein Nat. Biotechnol. 24, 79-88
23. Yang, Y. T., Peredelchuk, M., Bennett, G. N., and San, K. Y. (2000) Effect of variation of Klebsiella pneumoniae acetolactate synthase expression on metabolic flux redistribution in Escherichia coli Biotechnol. Bioeng. 69, 150-159
24. Oliver, J. W. K. and Atsumi, S. (2015) A carbon sink pathway increases carbon productivity in cyanobacteria Metab. Eng. 10.1016/j.ymben.2015.03.006
25. Polidoros, A. N., Pasentsis, K., and Tsaftaris, A. S. (2006) Rolling circle amplification-RACE: a method for simultaneous isolation of 5′ and 3′ cDNA ends from amplified cDNA templates Biotechniques 41, 35-36
26. Solovyev, V. and Salamov, A. (2011) Automatic annotation of microbial genomes and metagenomic sequences, in Metagenomics and its Applications in Agriculture, Biomedicine and Environmental Studies, pp 61-78, Nova Science Publishers, Hauppauge, NY.
27. Atsumi, S., Hanai, T., and Liao, J. C. (2008) Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels Nature 451, 86-89
28. Rodriguez, G. M., Tashiro, Y., and Atsumi, S. (2014) Expanding ester biosynthesis in Escherichia coli Nat. Chem. Biol. 10, 259-265
29. Rippka, R., Deruelles, J., Waterbury, J. B., Herdman, M., and Stanier, R. Y. (1979) Generic assignments, strain histories and properties of pure cultures of cyanobacteria J. Gen. Microbiol. 111, 1-61
30. Li, M. Z. and Elledge, S. J. (2007) Harnessing homologous recombination in vitro to generate recombinant DNA via SLIC Nat. Methods 4, 251-256
31. McEwen, J. T., Machado, I. M., Connor, M. R., and Atsumi, S. (2013) Engineering Synechococcus elongatus PCC 7942 for continuous growth under diurnal conditions Appl. Environ. Microbiol. 79, 1668-1675
32. Bustos, S. A. and Golden, S. S. (1992) Light-regulated expression of the psbD gene family in Synechococcus sp. strain PCC 7942: evidence for the role of duplicated psbD genes in cyanobacteria Mol. Gen. Genet. 232, 221-230
33. Andersson, C. R., Tsinoremas, N. F., Shelton, J., Lebedeva, N. V., Yarrow, J., Min, H., and Golden, S. S. (2000) Application of bioluminescence to the study of circadian rhythms in cyanobacteria Methods Enzymol. 305, 527-542
34. Golden, S. S., Brusslan, J., and Haselkorn, R. (1987) Genetic engineering of the cyanobacterial chromosome Methods Enzymol. 153, 215-231
35. Voges, O. and Proskauer, B. (1898) Beitraege zur ernaehrungsphysiologie und zur differential diagnose der bakterien der hemmorrhagischen septicamie Z. Hyg. 28, 20-32
36. Westerfield, W. W. (1945) A colorimetric determination of blood acetoin J. Biol. Chem. 161, 495-502