Genetic instability in cyanobacteria - An elephant in the room?

Frontiers in Bioengineering and Biotechnology

Volumn 2, Issue MAY, 2014, Pages

  Jones, Patrik R ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Biotechnology; Cyanobacteria; Genetic instability; Metabolic engineering; Mutation; RecA

Indexed keywords

BIOTECHNOLOGY; CARBON DIOXIDE; METABOLISM; SOLAR ENERGY;

CYANOBACTERIA; GENETIC INSTABILITY; MUTATION; RECA; RESEARCH GROUPS; SCIENTIFIC LITERATURE; SUSTAINABLE PRODUCTION;

METABOLIC ENGINEERING;

EID: 84908256048     PISSN: None     EISSN: 22964185     Source Type: Journal    
DOI: 10.3389/fbioe.2014.00012     Document Type: Article

References (34)

1. Hellingwerf, K. J. (2012). Engineering a cyanobacterial cell factory for production of lactic acid. Appl. Environ. Microbiol. 78, 7098-7106. doi: 10.1128/AEM.01587-12
2. Battesti, A., Majdalani, N., and Gottesman, S. (2011). The RpoS-mediated general stress response in Escherichia coli. Annu. Rev. Microbiol. 65, 189-213. doi:10.1146/annurev-micro-090110-102946
3. Bentley, F. K., Zurbriggen, A., and Melis, A. (2014). Heterologous expression of the mevalonic acid pathway in cyanobacteria enhances endogenous carbon partitioning to isoprene. Mol. Plant. 7, 71-86. doi:10.1093/mp/sst134
4. Dienst, D., Georg, J., Abts, T., Jakorew, L., Kuchmina, E., Borner, T., et al. (2014). Transcriptomic response to prolonged ethanol production in the cyanobacterium Synechocystis sp. PCC6803. Biotechnol. Biofuels 7, 21. doi:10.1186/1754-6834-7-21
5. Fijalkowska, I. J., Dunn, R. L., and Schaaper, R. M. (1997). Genetic requirements and mutational specificity of the Escherichia coli SOS mutator activity. J. Bacteriol. 179, 7435-7445.
6. Galhardo, R. S., Do, R., Yamada, M., Friedberg, E. C., Hastings, P. J., Nohmi, T., et al. (2009). DinB upregulation is the sole role of the SOS response in stress-induced mutagenesis in Escherichia coli. Genetics 182, 55-68. doi:10.1534/genetics.109.100735
7. Geerts, D., Bovy, A., De Vrieze, G., Borrias, M., and Weisbeek, P. (1995). Inducible expression of heterologous genes targeted to a chromosomal platform in the cyanobacterium Synechococcus sp. PCC 7942. Microbiology 141(Pt 4), 831-841. doi:10.1099/13500872-141-4-831
8. Guerrero, F., Carbonell, V., Cossu, M., Correddu, D., and Jones, P. R. (2012). Ethylene synthesis and regulated expression of recombinant protein in Synechocystis sp. PCC 6803. PLoS ONE 7:e50470. doi:10.1371/journal.pone.0050470
9. Huang, H. H., and Lindblad, P. (2013). Wide-dynamic-range promoters engineered for cyanobacteria. J. Biol. Eng. 7, 10. doi:10.1186/1754-1611-7-10
10. Ikeuchi, M., and Tabata, S. (2001). Synechocystis sp. PCC 6803-a useful tool in the study of the genetics of cyanobacteria. Photosyn. Res. 70, 73-83. doi:10.1023/A:1013887908680
11. 2 in a cyanobacterium. Metab. Eng. 21, 60-70. doi:10.1016/j.ymben.2013.11.004
12. Kämäräinen, J., Knoop, H., Stanford, N. J., Guerrero, F., Akhtar, M. K., Aro, E. M., et al. (2012). Physiological tolerance and stoichiometric potential of cyanobacteria for hydrocarbon fuel production. J. Biotechnol. 162, 67-74. doi:10.1016/j.jbiotec.2012.07.193
13. Kaneko, T., Sato, S., Kotani, H., Tanaka, A., Asamizu, E., Nakamura, Y., et al. (1996). Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions. DNA Res. 3, 109-136. doi:10.1093/dnares/3.3.109
14. Kanesaki, Y., Shiwa, Y., Tajima, N., Suzuki, M., Watanabe, S., Sato, N., et al. (2012). Identification of substrain-specific mutations by massively parallel whole-genome resequencing of Synechocystis sp. PCC 6803. DNA Res. 19, 67-79. doi:10.1093/dnares/dsr042
15. Kusakabe, T., Tatsuke, T., Tsuruno, K., Hirokawa, Y., Atsumi, S., Liao, J. C., et al. (2013). Engineering a synthetic pathway in cyanobacteria for isopropanol production directly from carbon dioxide and light. Metab. Eng. 20, 101-108. doi:10.1016/j.ymben.2013.09.007
16. Kuzminov, A. (1999). Recombinational repair of DNA damage in Escherichia coli and bacteriophage lambda. Microbiol. Mol. Biol. Rev. 63, 751-813.
17. Li, S., Xu, M., and Su, Z. (2010). Computational analysis of LexA regulons in cyanobacteria. BMC Genomics 11:527. doi:10.1186/1471-2164-11-527
18. Liu, J., Chen, L., Wang, J., Qiao, J., and Zhang, W. (2012). Proteomic analysis reveals resistance mechanism against biofuel hexane in Synechocystis sp. PCC 6803. Biotechnol. Biofuels 5, 68. doi:10.1186/1754-6834-5-68
19. McKenzie, G. J., Harris, R. S., Lee, P. L., and Rosenberg, S. M. (2000). The SOS response regulates adaptive mutation. Proc. Natl. Acad. Sci. U S A 97, 6646-6651. doi:10.1073/pnas.120161797
20. Michel, B. (2005). After 30 years of study, the bacterial SOS response still surprises us. PLoS Biol. 3:e255. doi:10.1371/journal.pbio.0030255
21. Mikami, K., Kanesaki, Y., Suzuki, I., and Murata, N. (2002). The histidine kinase Hik33 perceives osmotic stress and cold stress in Synechocystis sp PCC 6803. Mol. Microbiol. 46, 905-915. doi:10.1046/j.1365-2958.2002.03202.x
22. Minda, R., Ramchandani, J., Joshi, V. P., and Bhattacharjee, S. K. (2005). A homozygous recA mutant of Synechocystis PCC6803: construction strategy and characteristics eliciting a novel RecA independent UVC resistance in dark. Mol. Genet. Genomics 274, 616-624. doi:10.1007/s00438-005-0054-z
23. Murphy, R. C., Gasparich, G. E., Bryant, D. A., and Porter, R. D. (1990). Nucleotide sequence and further characterization of the Synechococcus sp. strain PCC 7002 recA gene: complementation of a cyanobacterial recA mutation by the Escherichia coli recA gene. J. Bacteriol. 172, 967-976.
24. Patterson-Fortin, L. M., Colvin, K. R., and Owttrim, G. W. (2006). A LexA-related protein regulates redox-sensitive expression of the cyanobacterial RNA helicase, crhR. Nucleic Acids Res. 34, 3446-3454. doi:10.1093/nar/gkl426
25. Qiao, J., Wang, J., Chen, L., Tian, X., Huang, S., Ren, X., et al. (2012). Quantitative iTRAQ LC-MS/MS proteomics reveals metabolic responses to biofuel ethanol in cyanobacterial Synechocystis sp. PCC 6803. J. Proteome Res. 11, 5286-5300. doi:10.1021/pr300504w
26. Shoumskaya, M. A., Paithoonrangsarid, K., Kanesaki, Y., Los, D. A., Zinchenko, V. V., Tanticharoen, M., et al. (2005). Identical Hik-Rre systems are involved in perception and transduction of salt signals and hyperosmotic signals but regulate the expression of individual genes to different extents in Synechocystis. J. Biol. Chem. 280, 21531-21538. doi:10.1074/jbc.M412174200
27. Sleight, S. C., and Sauro, H. M. (2013). Visualization of evolutionary stability dynamics and competitive fitness of Escherichia coli engineered with randomized multigene circuits. ACS Synth. Biol. 2, 519-528. doi:10.1021/sb400055h
28. Takahama, K., Matsuoka, M., Nagahama, K., and Ogawa, T. (2003). Construction and analysis of a recombinant cyanobacterium expressing a chromosomally inserted gene for an ethylene-forming enzyme at the psbAI locus. J. Biosci. Bioeng. 95, 302-305. doi:10.1263/jbb.95.302
29. Takahashi, H., Uchimiya, H., and Hihara, Y. (2008). Difference in metabolite levels between photoautotrophic and photomixotrophic cultures of Synechocystis sp. PCC 6803 examined by capillary electrophoresis electrospray ionization mass spectrometry. J. Exp. Bot. 59, 3009-3018. doi:10.1093/jxb/ern157
30. Tian, X., Chen, L., Wang, J., Qiao, J., and Zhang, W. (2013). Quantitative proteomics reveals dynamic responses of Synechocystis sp. PCC 6803 to next-generation biofuel butanol. J. Proteomics 78, 326-345. doi:10.1016/j.jprot.2012.10.002
31. Trautmann, D., Voss, B., Wilde, A., Al-Babili, S., and Hess, W. R. (2012). Microevolution in cyanobacteria: re-sequencing a motile substrain of Synechocystis sp. PCC 6803. DNA Res. 19, 435-448. doi:10.1093/dnares/dss024
32. Tyo, K. E., Ajikumar, P. K., and Stephanopoulos, G. (2009). Stabilized gene duplication enables long-term selection-free heterologous pathway expression. Nat. Biotechnol. 27, 760-765. doi:10.1038/nbt.1555
33. Wang, H., Zhang, W., Chen, L., Wang, J., and Liu, T. (2013). The contamination and control of biological pollutants in mass cultivation of microalgae. Bioresour. Technol. 128, 745-750. doi:10.1016/j.biortech.2012.10.158
34. Zhu, H., Ren, X., Wang, J., Song, Z., Shi, M., Qiao, J., et al. (2013). Integrated OMICS guided engineering of biofuel butanol-tolerance in photosynthetic Synechocystis sp. PCC 6803. Biotechnol. Biofuels 6, 106. doi:10.1186/1754-6834-6-106