Mildly reduced brain swelling and improved neurological outcome in aquaporin-4 knockout mice following controlled cortical impact brain injury

Journal of Neurotrauma

Volumn 32, Issue 19, 2015, Pages 1558-1564

  Yao, Xiaoming ^a,b   Uchida, Kazuyoshi ^a   Papadopoulos, Marios C ^c   Zador, Zsolt ^a   Manley, Geoffrey T ^a   Verkman, Alan S ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

AQP4; brain edema; brain trauma; controlled cortical impact injury; cytotoxic edema

Indexed keywords

AQUAPORIN 4; EVANS BLUE; AQP4 PROTEIN, MOUSE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; BRAIN CAPILLARY; BRAIN EDEMA; BRAIN WATER; CONTROLLED STUDY; CRANIOTOMY; DISEASE ASSOCIATION; EXPERIMENTAL BRAIN INJURY; EXTRAVASATION; GENE DELETION; GENERAL PATHOLOGICAL PARAMETERS; GRAVIMETRY; INJURY; INJURY SEVERITY; INJURY VOLUME; INTRACRANIAL PRESSURE; KNOCKOUT MOUSE; MALE; MEMBRANE DAMAGE; MOUSE; NEUROTRAUMATOLOGY; NONHUMAN; OUTCOME ASSESSMENT; TRANSMISSION ELECTRON MICROSCOPY; WILD TYPE; ANIMAL; BRAIN INJURY; CAPILLARY; COMPLICATION; GENETICS; NERVOUS SYSTEM DISEASES; PATHOLOGY; PSYCHOLOGY; ULTRASTRUCTURE;

ANIMALS; AQUAPORIN 4; ASTROCYTES; BEHAVIOR, ANIMAL; BLOOD-BRAIN BARRIER; BRAIN EDEMA; BRAIN INJURIES; CAPILLARIES; CRANIOTOMY; INTRACRANIAL PRESSURE; MALE; MICE; MICE, KNOCKOUT; NERVOUS SYSTEM DISEASES;

EID: 84942436337     PISSN: 08977151     EISSN: 15579042     Source Type: Journal    
DOI: 10.1089/neu.2014.3675     Document Type: Article

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