Relationship between AQP4 expression and structural damage to the blood-brain barrier at early stages of traumatic brain injury in rats

Chinese Medical Journal

Volumn 126, Issue 22, 2013, Pages 4316-4321

  Lu, Hong ^a   Lei, Xiao Yan ^a   Hu, Hui ^a   He, Zhan Ping ^a  

^a Central South University   (China)

Author keywords

Animal experiment; Aquaporins; Blood brain barrier; Brain injury; Edema

Indexed keywords

AQUAPORIN 4; IMMUNOGLOBULIN G;

ANGIONEUROTIC EDEMA; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN EDEMA; BRAIN WATER; CELL INFILTRATION; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; GLIA CELL; IMMUNOHISTOCHEMISTRY; MALE; MITOCHONDRION SWELLING; NONHUMAN; PROTEIN EXPRESSION; RAT; TISSUE NECROSIS; TRANSMISSION ELECTRON MICROSCOPY; TRAUMATIC BRAIN INJURY; WESTERN BLOTTING;

ANIMALS; AQUAPORIN 4; BLOOD-BRAIN BARRIER; BLOTTING, WESTERN; BRAIN EDEMA; BRAIN INJURIES; IMMUNOHISTOCHEMISTRY; RATS; RATS, WISTAR;

EID: 84887574110     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.20131139     Document Type: Article

References (30)

1. Sabre L, Tomberg T, Kõrv J, Kepler J, Kepler K, Linnamägi U, et al. Brain activation in the acute phase of traumatic spinal cord injury. Spinal Cord 2013; May 21. doi: 10.1038/sc.2013.41. Epub ahead of print.
2. Suzuki R, Okuda M, Asai J, Nagashima G, Itokawa H, Matsunaga A, et al. Astrocytes co-express aquaporin-1,-4 and vascular endothelial growth factor in brain edema tissue associated with brain contusion. Acta Neurochir Suppl 2006; 96: 398-401.
3. Yao X, Hrabetova S, Nicholson C, Manley GT. Aquaporin-4-deficient mice have increased extracellular space without tortuosity change. J Neurosci 2008; 28: 5460-5464.
4. Zhang L, Yun F. Enhanced expression of aquaporin-4 aggravates brain edema after traumatic brain injury in rat. J Capital Med Univ (Chin) 2008; 29: 732-736.
5. Kiening KL, van Landeghem FK, Schreiber S, Thomale UW, von Deimling A, Unterberg AW, et al. Decreased hemispheric aquaporin-4 is linked to evolving brain edema following controlled cortical impact injury in rats. Neurosci Lett 2002; 24: 105-108.
6. Fukuda AM, Pop V, Spagnoli D, Ashwal S, Obenaus A, Badaut J. Delayed increase of astrocytic aquaporin 4 after juvenile traumatic brain injury: possible role in edema resolution? Neuroscience 2012; 222: 366-378.
7. Zhao J, Moore AN, Clifton GL, Dash PK. Sulforaphane enhances aquaporin-4 expression and decreases cerebral edema following traumatic brain injury. J Neurosci Res 2005; 82: 499-506.
8. Feeney BM, Boyeson MG, Limn RT, Murray HM, Dail WG. Responses to cortical injury: 1: Methodology and local effects of contusion in the rats. Brain Res 1981; 211: 67-77.
9. Akiguchi I, Tomimoto H, Suenaga T, Wakita H, Budka H. Blood-brain barrier dysfunction in Binswanger's disease; an immunohistochemical study. Acta Neuropathol 1998; 95: 78-84.
10. Tait MJ, Saadoun S, Bell BA, Papadopoulos MC. Water movements in the brain: role of aquaporins. Trends Neurosci 2008; 31: 37-43.
11. Yao X, Hrabetova S, Nicholson C, Manley GT. Aquaporin-4-deficient mice have increased extracellular space without tortuosity change. J Neurosci 2008; 28: 5460-5464.
12. Easton AS. Regulation of permeability across the blood-brain barrier. Adv Exp Med Biol 2012; 763: 1-19.
13. Cui Y, Zhang L,Yuan F. Disruption of blood-brain barrier permeabitity after brain trauma in rats. Chin J Rehabil Theory Practice (Chin) 2006; 12: 649-650.
14. Wei XE, Zhang YZ, Li YH, Li MH, Li WB. Dynamics of rabbit brain edema in focal lesion and perilesion area after traumatic brain injury: a MRI study. J Neurotrauma 2012; 29: 2413-2420.
15. Lescot T, Fulla-Oller L, Po C, Chen XR, Puybasset L, Gillet B, et al. Temporal and regional changes after focal traumatic brain injury. J Neurotrauma 2010; 27: 85-94.
16. Zhang SG, Pan TH, He AL, Gong WY, Shi L, Zhou JF. Expression of aquaporin-4 in the brain tissues from patients with severe brain injuries and its significance. Chin J Traumatol (Chin) 2010; 26: 589-591.
17. Denker BM, Smith BL, Kuhajda FP, Agre P. Identification, purification, and partial characterization of a novel Mr 28,000 integral membrane protein from erythrocytes and renal tubules. J Biol Chem 1988; 263: 15634-15642.
18. Hirt L, Price M, Ternon B, Mastour N, Brunet JF, Badaut J. Early induction of AQP4 contributes the limitation of the edema formation in the brain ischemia. J Cereb Blood Flow Metab 2009; 29: 423-433.
19. Saadoun S, Tait MJ, Reza A, Davies DC, Bell BA, Verkman AS, et al. AQP4 gene deletion in mice does not alter blood-brain barrier integrity or brain morphology. Neurosci 2009; 161: 764-772.
20. Hu H, Lu H, He Z, Han X, Chen J, Tu R. Gene interference regulates aquaporin-4 expression in swollen tissue of rats with cerebral ischemic edema: Correlation with variation in apparent diffusion coefficient. Neural Regen Res 2012; 7: 1659-1666.
21. Lu H, Hu H, He ZP. Reperfusion of the rat brain tissues following acute ischemia: the correlation among diffusion-weighted imaging, histopathology, and aquaporin-4 expression. Chin Med J 2011; 124: 3148-3153.
22. Lu H, Hu H, He ZP. AQP4 expression in hypoxic cultured astrocytes can be inhibited by AQP4 mRNA silence in vitro. Chin J Anatomy (Chin) 2011; 34: 47-50.
23. Manley GT, Binder DK, Papadopoulos MC, Verkman AS. New insights into water transport and edema in the central nervous system from phenotype analysis of aquaporin-4 null mice. Neuroscience 2004; 129: 981-989.
24. Liu H, Sun SQ, Yang M, Qiu GP, Yu WH, Zuo F. Role of aquaporin-4 in the formation of brain edema after mild traumatic brain injury in rat. Chin J Anatomy (Chin) 2009; 32: 68-72.
25. Li M, Yu B, Luo FF, Shi YX, Li H. Expression alteration of aquaporin 4 in cortex of the traumatic brain injury rats. Progress Anatom Sci 2011; 17: 12-15.
26. Lo Pizzo M, Schiera G, Di Liegro I, Di Liegro CM, Pál J, Czeiter E, et al. Aquaporin-4 distribution in control and stressed astrocytes in culture and in the cerebrospinal fluid of patients with traumatic brain injuries. Neurol Sci 2012; Nov 10. Epub ahead of print.
27. Yeung CM, Lo AC, Cheung AK, Chung SS, Wong D, Chung SK. More severe type 2 diabetes-associated ischemic stroke injury is alleviated in aldose reductase-deficient mice. J Neurosci Res 2010; 88: 2026-2034.
28. Ren Z, Iliff JJ, Yang L, Yang J, Chen X, Chen MJ, et al. Hit & Run' model of closed-skull traumatic brain injury (TBI) reveals complex patterns of post-traumatic AQP4 dysregulation. J Cereb Blood Flow Metab 2013; Feb 27. doi: 10.1038/jcbfm.2013.30. Epub ahead of print.
29. Katada R, Nishitani Y, Honmou O, Mizuo K, Okazaki S, Tateda K, et al. Expression of aquaporin-4 augments cytotoxic brain edema after traumatic brain injury during acute ethanol exposure. Am J Pathol 2012; 180: 17-23.
30. Lu H, Hu H, He ZP, Tu R, Shu QJ. AQP4 expression of the cerebral ischemic tissue following its mRNA silence in rat. Chin J Anatomy (Chin) 2012; 35: 4-8.