Greatly improved survival and neuroprotection in aquaporin-4-knockout mice following global cerebral ischemia

FASEB Journal

Volumn 28, Issue 2, 2014, Pages 705-714

  Katada, Ryuichi ^a   Akdemir, Gokhan ^a   Asavapanumas, Nithi ^a   Ratelade, Julien ^a   Zhang, Hua ^a   Verkman, A S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Astrocyte; Brain swelling; Neuroscience; Water channel

Indexed keywords

ALPHA SYNTROPHIN; AQUAPORIN 4; CASPASE 3; CD45 ANTIGEN; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUCOSE; INTERLEUKIN 17; INTERLEUKIN 6; MYELIN BASIC PROTEIN; OXYGEN; SYNTROPHIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ARTIFICIAL VENTILATION; ASTROCYTE; BLOOD BRAIN BARRIER; BRAIN BLOOD FLOW; BRAIN CORTEX; BRAIN HOMOGENATE; BRAIN ISCHEMIA; BRAIN WATER; BRAIN WEIGHT; CAROTID ARTERY OBSTRUCTION; CELL ACTIVATION; CELL LOSS; CELL MEMBRANE; CELL SWELLING; CONTROLLED STUDY; CYTOTOXICITY; DRUG EXTRAVASATION; DRY WEIGHT; EXTRAVASATION; GENE DELETION; HEART ARREST; HIPPOCAMPUS; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE; INTRACRANIAL PRESSURE; LEUKOCYTE; MALE; MICROGLIA; MOUSE; NEUROPROTECTION; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RESPIRATORY DISTRESS; SURVIVAL; WATER PERMEABILITY; WATER TRANSPORT; WET WEIGHT; ANIMAL; BRAIN SWELLING; C57BL MOUSE; GENETICS; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; METABOLISM; NEUROSCIENCE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; WATER CHANNEL;

ASTROCYTE; BRAIN SWELLING; NEUROSCIENCE; WATER CHANNEL;

ANIMALS; AQUAPORIN 4; BRAIN ISCHEMIA; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; INTRACRANIAL PRESSURE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT;

EID: 84897049687     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.13-231274     Document Type: Article

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