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Volumn 117, Issue 1, 2015, Pages 17-28

Functional Analysis and Transcriptomic Profiling of iPSC-Derived Macrophages and Their Application in Modeling Mendelian Disease

Author keywords

cholesterol; genomics; induced pluripotent stem cells; inflammation; macrophages

Indexed keywords

ABC TRANSPORTER A1; APOLIPOPROTEIN A1; CD68 ANTIGEN; CD86 ANTIGEN; CELL PROTEIN; CHOLESTEROL; COMPLEMENT COMPONENT C5A; CXCL1 CHEMOKINE; CXCL9 CHEMOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HIGH DENSITY LIPOPROTEIN 3; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; RNA; TRANSCRIPTOME; TUMOR NECROSIS FACTOR; ABCA1 PROTEIN, HUMAN; ABCA1 PROTEIN, MOUSE; DIFFERENTIATION ANTIGEN; LIPOPOLYSACCHARIDE; MESSENGER RNA;

EID: 84942427887     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.117.305860     Document Type: Article
Times cited : (104)

References (31)
  • 1
    • 84876800337 scopus 로고    scopus 로고
    • Macrophage biology in development, homeostasis and disease
    • Wynn TA, Chawla A, Pollard JW. Macrophage biology in development, homeostasis and disease. Nature. 2013;496:445-455. doi: 10.1038/nature12034.
    • (2013) Nature , vol.496 , pp. 445-455
    • Wynn, T.A.1    Chawla, A.2    Pollard, J.W.3
  • 2
    • 0036790413 scopus 로고    scopus 로고
    • Consequences of cellular cholesterol accumulation: Basic concepts and physiological implications
    • Tabas I. Consequences of cellular cholesterol accumulation: basic concepts and physiological implications. J Clin Invest. 2002;110:905-911. doi: 10.1172/JCI16452.
    • (2002) J Clin Invest , vol.110 , pp. 905-911
    • Tabas, I.1
  • 3
    • 84862528505 scopus 로고    scopus 로고
    • Induced pluripotent stem cells: Past, present, and future
    • Yamanaka S. Induced pluripotent stem cells: past, present, and future. Cell Stem Cell. 2012;10:678-684. doi: 10.1016/j.stem.2012.05.005.
    • (2012) Cell Stem Cell , vol.10 , pp. 678-684
    • Yamanaka, S.1
  • 4
    • 84884826708 scopus 로고    scopus 로고
    • Transcriptome comparison of human neurons generated using induced pluripotent stem cells derived from dental pulp and skin fibroblasts
    • Chen J, Lin M, Foxe JJ, Pedrosa E, Hrabovsky A, Carroll R, Zheng D, Lachman HM. Transcriptome comparison of human neurons generated using induced pluripotent stem cells derived from dental pulp and skin fibroblasts. PLoS One. 2013;8:e75682. doi: 10.1371/journal.pone.0075682.
    • (2013) PLoS One , vol.8
    • Chen, J.1    Lin, M.2    Foxe, J.J.3    Pedrosa, E.4    Hrabovsky, A.5    Carroll, R.6    Zheng, D.7    Lachman, H.M.8
  • 14
    • 73349116606 scopus 로고    scopus 로고
    • Network visualization and analysis of gene expression data using BioLayout Express(3D)
    • Theocharidis A, van Dongen S, Enright AJ, Freeman TC. Network visualization and analysis of gene expression data using BioLayout Express(3D). Nat Protoc. 2009;4:1535-1550. doi: 10.1038/nprot.2009.177.
    • (2009) Nat Protoc , vol.4 , pp. 1535-1550
    • Theocharidis, A.1    Van Dongen, S.2    Enright, A.J.3    Freeman, T.C.4
  • 15
    • 84894102230 scopus 로고    scopus 로고
    • Transcriptome-based network analysis reveals a spectrum model of human macrophage activation
    • Xue J, Schmidt SV, Sander J, et al. Transcriptome-based network analysis reveals a spectrum model of human macrophage activation. Immunity. 2014;40:274-288. doi: 10.1016/j.immuni.2014.01.006.
    • (2014) Immunity , vol.40 , pp. 274-288
    • Xue, J.1    Schmidt, S.V.2    Sander, J.3
  • 16
    • 77958471357 scopus 로고    scopus 로고
    • Differential expression analysis for sequence count data
    • Anders S, Huber W. Differential expression analysis for sequence count data. Genome Biol. 2010;11:R106. doi: 10.1186/gb-2010-11-10-r106.
    • (2010) Genome Biol , vol.11 , pp. R106
    • Anders, S.1    Huber, W.2
  • 18
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y. Controlling the false discovery rate: A practical and powerful approach to multiple testing. J Roy Stat Soc Ser B (Methodological). 1995;57:289-300.
    • (1995) J Roy Stat Soc ser B (Methodological) , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 19
    • 24044440971 scopus 로고    scopus 로고
    • BiNGO: A Cytoscape plugin to assess overrepresentation of gene ontology categories in biological networks
    • Maere S, Heymans K, Kuiper M. BiNGO: a Cytoscape plugin to assess overrepresentation of gene ontology categories in biological networks. Bioinformatics. 2005;21:3448-3449. doi: 10.1093/bioinformatics/bti551.
    • (2005) Bioinformatics , vol.21 , pp. 3448-3449
    • Maere, S.1    Heymans, K.2    Kuiper, M.3
  • 21
    • 61449243725 scopus 로고    scopus 로고
    • Macrophage phagocytosis of apoptotic neutrophils is critically regulated by the opposing actions of pro-inflammatory and anti-inflammatory agents: Key role for TNF-alpha
    • Michlewska S, Dransfield I, Megson IL, Rossi AG. Macrophage phagocytosis of apoptotic neutrophils is critically regulated by the opposing actions of pro-inflammatory and anti-inflammatory agents: key role for TNF-alpha. FASEB J. 2009;23:844-854. doi: 10.1096/fj.08-121228.
    • (2009) FASEB J , vol.23 , pp. 844-854
    • Michlewska, S.1    Dransfield, I.2    Megson, I.L.3    Rossi, A.G.4
  • 22
    • 0035988351 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide induces expression of ABCA1 but not ABCG1 via an LXRindependent pathway
    • Kaplan R, Gan X, Menke JG, Wright SD, Cai TQ. Bacterial lipopolysaccharide induces expression of ABCA1 but not ABCG1 via an LXRindependent pathway. J Lipid Res. 2002;43:952-959.
    • (2002) J Lipid Res , vol.43 , pp. 952-959
    • Kaplan, R.1    Gan, X.2    Menke, J.G.3    Wright, S.D.4    Cai, T.Q.5
  • 23
    • 33750813483 scopus 로고    scopus 로고
    • Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: New molecules and patterns of gene expression
    • Martinez FO, Gordon S, Locati M, Mantovani A. Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. J Immunol. 2006;177:7303-7311.
    • (2006) J Immunol , vol.177 , pp. 7303-7311
    • Martinez, F.O.1    Gordon, S.2    Locati, M.3    Mantovani, A.4
  • 26
    • 84878660493 scopus 로고    scopus 로고
    • Deficiency of ATP-binding cassette transporters A1 and G1 in macrophages increases inflammation and accelerates atherosclerosis in mice
    • Westerterp M, Murphy AJ, Wang M, et al. Deficiency of ATP-binding cassette transporters A1 and G1 in macrophages increases inflammation and accelerates atherosclerosis in mice. Circ Res. 2013;112:1456-1465. doi: 10.1161/CIRCRESAHA.113.301086.
    • (2013) Circ Res , vol.112 , pp. 1456-1465
    • Westerterp, M.1    Murphy, A.J.2    Wang, M.3
  • 27
    • 84881506946 scopus 로고    scopus 로고
    • Efficient, long term production of monocyte-derived macrophages from human pluripotent stem cells under partly-defined and fully-defined conditions
    • van Wilgenburg B, Browne C, Vowles J, Cowley SA. Efficient, long term production of monocyte-derived macrophages from human pluripotent stem cells under partly-defined and fully-defined conditions. PLoS One. 2013;8:e71098. doi: 10.1371/journal.pone.0071098.
    • (2013) PLoS One , vol.8
    • Van Wilgenburg, B.1    Browne, C.2    Vowles, J.3    Cowley, S.A.4
  • 30
    • 78149355932 scopus 로고    scopus 로고
    • Macrophage ABCA1 reduces MyD88-dependent Toll-like receptor trafficking to lipid rafts by reduction of lipid raft cholesterol
    • Zhu X, Owen JS, Wilson MD, Li H, Griffiths GL, Thomas MJ, Hiltbold EM, Fessler MB, Parks JS. Macrophage ABCA1 reduces MyD88-dependent Toll-like receptor trafficking to lipid rafts by reduction of lipid raft cholesterol. J Lipid Res. 2010;51:3196-3206. doi: 10.1194/jlr.M006486.
    • (2010) J Lipid Res , vol.51 , pp. 3196-3206
    • Zhu, X.1    Owen, J.S.2    Wilson, M.D.3    Li, H.4    Griffiths, G.L.5    Thomas, M.J.6    Hiltbold, E.M.7    Fessler, M.B.8    Parks, J.S.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.