메뉴 건너뛰기




Volumn 29, Issue 5, 2015, Pages 927-941

Macrophage Activation Syndrome

Author keywords

Hemophagocytic lymphohistiocytosis; Hemophagocytic syndrome; Interleukin 1 inhibitors; Macrophage activation syndrome; Proinflammatory cytokines; Systemic juvenile idiopathic arthritis

Indexed keywords

CYCLOPHOSPHAMIDE; ETANERCEPT; ETOPOSIDE; IMMUNOGLOBULIN; THYMOCYTE ANTIBODY; TOCILIZUMAB;

EID: 84942370294     PISSN: 08898588     EISSN: 15581977     Source Type: Journal    
DOI: 10.1016/j.hoc.2015.06.010     Document Type: Review
Times cited : (120)

References (77)
  • 1
    • 70350554826 scopus 로고    scopus 로고
    • Macrophage activation syndrome
    • Elsevier, Amsterdam, T.H. Lehman, R. Cimaz (Eds.)
    • Ravelli A., Martini A. Macrophage activation syndrome. Pediatric rheumatology 2008, 55-63. Elsevier, Amsterdam. T.H. Lehman, R. Cimaz (Eds.).
    • (2008) Pediatric rheumatology , pp. 55-63
    • Ravelli, A.1    Martini, A.2
  • 2
    • 84882534599 scopus 로고    scopus 로고
    • Macrophage activation syndrome
    • Saunders Elsevier, Philadelphia, J. Cassidy, R.E. Petty (Eds.)
    • Grom A.A. Macrophage activation syndrome. Textbook of pediatric rheumatology 2010, 674-681. Saunders Elsevier, Philadelphia. 6th edition. J. Cassidy, R.E. Petty (Eds.).
    • (2010) Textbook of pediatric rheumatology , pp. 674-681
    • Grom, A.A.1
  • 3
    • 84938062112 scopus 로고    scopus 로고
    • Reactive hemophagocytic syndrome in adult-onset Still disease: clinical features, predictive factors, and prognosis in 21 patients
    • Bae C.B., Jung J.Y., Kim H.A., et al. Reactive hemophagocytic syndrome in adult-onset Still disease: clinical features, predictive factors, and prognosis in 21 patients. Medicine (Baltimore) 2015, 94(4):e451.
    • (2015) Medicine (Baltimore) , vol.94 , Issue.4 , pp. e451
    • Bae, C.B.1    Jung, J.Y.2    Kim, H.A.3
  • 4
    • 70350555315 scopus 로고    scopus 로고
    • Macrophage activation syndrome in juvenile systemic lupus erythematosus: a multinational multicenter study of thirty-eight patients
    • Parodi A., Davi S., Pringe A.B., et al. Macrophage activation syndrome in juvenile systemic lupus erythematosus: a multinational multicenter study of thirty-eight patients. Arthritis Rheum 2009, 60(11):3388-3399.
    • (2009) Arthritis Rheum , vol.60 , Issue.11 , pp. 3388-3399
    • Parodi, A.1    Davi, S.2    Pringe, A.B.3
  • 5
    • 33744793199 scopus 로고    scopus 로고
    • Characteristic and long-term outcome of 15 episodes of systemic lupus erythematosus-associated hemophagocytic syndrome
    • Lambotte O., Khellaf M., Harmouche H., et al. Characteristic and long-term outcome of 15 episodes of systemic lupus erythematosus-associated hemophagocytic syndrome. Medicine (Baltimore) 2006, 85(3):169-182.
    • (2006) Medicine (Baltimore) , vol.85 , Issue.3 , pp. 169-182
    • Lambotte, O.1    Khellaf, M.2    Harmouche, H.3
  • 6
    • 77956113583 scopus 로고    scopus 로고
    • Macrophage activation syndrome/hemophagocytic lymphohistiocytosis and Kawasaki disease
    • Simonini G., Pagnini I., Innocenti L., et al. Macrophage activation syndrome/hemophagocytic lymphohistiocytosis and Kawasaki disease. Pediatr Blood Cancer 2010, 55(3):592.
    • (2010) Pediatr Blood Cancer , vol.55 , Issue.3 , pp. 592
    • Simonini, G.1    Pagnini, I.2    Innocenti, L.3
  • 7
    • 34248157320 scopus 로고    scopus 로고
    • Large pericardial effusion requiring pericardiocentesis as cardinal sign of macrophage activation syndrome in systemic onset-juvenile idiopathic arthritis
    • Rigante D., De Rosa G., Bertoni B., et al. Large pericardial effusion requiring pericardiocentesis as cardinal sign of macrophage activation syndrome in systemic onset-juvenile idiopathic arthritis. Rheumatol Int 2007, 27(8):767-770.
    • (2007) Rheumatol Int , vol.27 , Issue.8 , pp. 767-770
    • Rigante, D.1    De Rosa, G.2    Bertoni, B.3
  • 8
    • 79958838809 scopus 로고    scopus 로고
    • Macrophage activation syndrome revealing familial Mediterranean fever
    • Rossi-Semerano L., Hermeziu B., Fabre M., et al. Macrophage activation syndrome revealing familial Mediterranean fever. Arthritis Care Res (Hoboken) 2011, 63(5):780-783.
    • (2011) Arthritis Care Res (Hoboken) , vol.63 , Issue.5 , pp. 780-783
    • Rossi-Semerano, L.1    Hermeziu, B.2    Fabre, M.3
  • 9
    • 0021804014 scopus 로고
    • Acute hemorrhagic, hepatic and neurologic manifestations in juvenile rheumatoid arthritis: possible relationship to drugs or infection
    • Hadchouel M., Prieur A.M., Griscelli C. Acute hemorrhagic, hepatic and neurologic manifestations in juvenile rheumatoid arthritis: possible relationship to drugs or infection. J Pediatr 1985, 106:562-566.
    • (1985) J Pediatr , vol.106 , pp. 562-566
    • Hadchouel, M.1    Prieur, A.M.2    Griscelli, C.3
  • 10
    • 0027364029 scopus 로고
    • Macrophage activation syndrome and rheumatic disease in childhood: a report of four new cases
    • Stephan J.L., Zeller J., Hubert P., et al. Macrophage activation syndrome and rheumatic disease in childhood: a report of four new cases. Clin Exp Rheumatol 1993, 11(4):451-456.
    • (1993) Clin Exp Rheumatol , vol.11 , Issue.4 , pp. 451-456
    • Stephan, J.L.1    Zeller, J.2    Hubert, P.3
  • 11
    • 0346218149 scopus 로고    scopus 로고
    • Macrophage activation syndrome-what's in a name!
    • Ramanan A.V., Schneider R. Macrophage activation syndrome-what's in a name!. J Rheumatol 2003, 30:2513-2516.
    • (2003) J Rheumatol , vol.30 , pp. 2513-2516
    • Ramanan, A.V.1    Schneider, R.2
  • 12
    • 77949448549 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis (HLH) and related disorders
    • Filipovich A.H. Hemophagocytic lymphohistiocytosis (HLH) and related disorders. Hematology Am Soc Hematol Educ Program 2009, 127-131.
    • (2009) Hematology Am Soc Hematol Educ Program , pp. 127-131
    • Filipovich, A.H.1
  • 13
    • 0030767987 scopus 로고    scopus 로고
    • Contemporary classification of histiocytic disorders. The WHO Committee On Histiocytic/Reticulum Cell Proliferations. Reclassification Working Group of the Histiocyte Society
    • Favara B.E., Feller A.C., Pauli M., et al. Contemporary classification of histiocytic disorders. The WHO Committee On Histiocytic/Reticulum Cell Proliferations. Reclassification Working Group of the Histiocyte Society. Med Pediatr Oncol 1997, 29(3):157-166.
    • (1997) Med Pediatr Oncol , vol.29 , Issue.3 , pp. 157-166
    • Favara, B.E.1    Feller, A.C.2    Pauli, M.3
  • 14
    • 34248666067 scopus 로고    scopus 로고
    • Occult macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis
    • Behrens E.M., Beukelman T., Paessler M., et al. Occult macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis. J Rheumatol 2007, 34(5):1133-1138.
    • (2007) J Rheumatol , vol.34 , Issue.5 , pp. 1133-1138
    • Behrens, E.M.1    Beukelman, T.2    Paessler, M.3
  • 15
    • 33947158702 scopus 로고    scopus 로고
    • The diagnostic significance of soluble CD163 and soluble interleukin-2 receptor alpha-chain in macrophage activation syndrome and untreated new-onset systemic juvenile idiopathic arthritis
    • Bleesing J., Prada A., Siegel D.M., et al. The diagnostic significance of soluble CD163 and soluble interleukin-2 receptor alpha-chain in macrophage activation syndrome and untreated new-onset systemic juvenile idiopathic arthritis. Arthritis Rheum 2007, 56(3):965-971.
    • (2007) Arthritis Rheum , vol.56 , Issue.3 , pp. 965-971
    • Bleesing, J.1    Prada, A.2    Siegel, D.M.3
  • 16
    • 84925581550 scopus 로고    scopus 로고
    • Clinical features, treatment and outcome of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis: A multinational, multicenter study of 362 patients
    • Minoia F., Davi S., Horne A., et al. Clinical features, treatment and outcome of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis: A multinational, multicenter study of 362 patients. Arthritis Rheumatol 2014, 66(11):3160-3169.
    • (2014) Arthritis Rheumatol , vol.66 , Issue.11 , pp. 3160-3169
    • Minoia, F.1    Davi, S.2    Horne, A.3
  • 17
    • 84939607119 scopus 로고    scopus 로고
    • Dissecting the heterogeneity of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis
    • Minoia F., Davì S., Horne A., et al. Dissecting the heterogeneity of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis. J Rheumatol 2015, 42(6):994-1001.
    • (2015) J Rheumatol , vol.42 , Issue.6 , pp. 994-1001
    • Minoia, F.1    Davì, S.2    Horne, A.3
  • 18
    • 84921412381 scopus 로고    scopus 로고
    • Pathogenesis of macrophage activation syndrome and potential for cytokine-directed therapies
    • Schulert G.S., Grom A.A. Pathogenesis of macrophage activation syndrome and potential for cytokine-directed therapies. Annu Rev Med 2015, 66:145-159.
    • (2015) Annu Rev Med , vol.66 , pp. 145-159
    • Schulert, G.S.1    Grom, A.A.2
  • 19
    • 84905503868 scopus 로고    scopus 로고
    • Hyperinflammation, rather than hemophagocytosis, is the common link between macrophage activation syndrome and hemophagocytic lymphohistiocytosis
    • Weaver L.K., Behrens E.M. Hyperinflammation, rather than hemophagocytosis, is the common link between macrophage activation syndrome and hemophagocytic lymphohistiocytosis. Curr Opin Rheumatol 2014, 26(5):562-569.
    • (2014) Curr Opin Rheumatol , vol.26 , Issue.5 , pp. 562-569
    • Weaver, L.K.1    Behrens, E.M.2
  • 20
    • 84861685616 scopus 로고    scopus 로고
    • Macrophage activation syndrome as part of systemic juvenile idiopathic arthritis: diagnosis, genetics, pathophysiology and treatment
    • Ravelli A., Grom A.A., Behrens E.M., et al. Macrophage activation syndrome as part of systemic juvenile idiopathic arthritis: diagnosis, genetics, pathophysiology and treatment. Genes Immun 2012, 13(4):289-298.
    • (2012) Genes Immun , vol.13 , Issue.4 , pp. 289-298
    • Ravelli, A.1    Grom, A.A.2    Behrens, E.M.3
  • 21
    • 33845619137 scopus 로고    scopus 로고
    • HLH-2004: diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis
    • Henter J.I., Horne A., Arico M., et al. HLH-2004: diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer 2007, 48(2):124-131.
    • (2007) Pediatr Blood Cancer , vol.48 , Issue.2 , pp. 124-131
    • Henter, J.I.1    Horne, A.2    Arico, M.3
  • 22
    • 0031670358 scopus 로고    scopus 로고
    • Defective natural killer cell function in patients with hemophagocytic lymphohistiocytosis and in first degree relatives
    • Sullivan K.E., Delaat C.A., Douglas S.D., et al. Defective natural killer cell function in patients with hemophagocytic lymphohistiocytosis and in first degree relatives. Pediatr Res 1998, 44(4):465-468.
    • (1998) Pediatr Res , vol.44 , Issue.4 , pp. 465-468
    • Sullivan, K.E.1    Delaat, C.A.2    Douglas, S.D.3
  • 23
    • 0033520970 scopus 로고    scopus 로고
    • Perforin gene defects in familial hemophagocytic lymphohistiocytosis
    • Stepp S.E., Dufourcq-Lagelouse R., Deist F.L., et al. Perforin gene defects in familial hemophagocytic lymphohistiocytosis. Science 1999, 286(5446):1957-1959.
    • (1999) Science , vol.286 , Issue.5446 , pp. 1957-1959
    • Stepp, S.E.1    Dufourcq-Lagelouse, R.2    Deist, F.L.3
  • 24
    • 10744224641 scopus 로고    scopus 로고
    • Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3)
    • Feldmann J., Callebaut I., Raposo G., et al. Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3). Cell 2003, 115(4):461-473.
    • (2003) Cell , vol.115 , Issue.4 , pp. 461-473
    • Feldmann, J.1    Callebaut, I.2    Raposo, G.3
  • 25
    • 70350500464 scopus 로고    scopus 로고
    • Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11
    • Zur S.U., Rohr J., Seifert W., et al. Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11. Am J Hum Genet 2009, 85(4):482-492.
    • (2009) Am J Hum Genet , vol.85 , Issue.4 , pp. 482-492
    • Zur, S.U.1    Rohr, J.2    Seifert, W.3
  • 26
    • 20144363940 scopus 로고    scopus 로고
    • Linkage of familial hemophagocytic lymphohistiocytosis (FHL) type-4 to chromosome 6q24 and identification of mutations in syntaxin 11
    • Zur S.U., Schmidt S., Kasper B., et al. Linkage of familial hemophagocytic lymphohistiocytosis (FHL) type-4 to chromosome 6q24 and identification of mutations in syntaxin 11. Hum Mol Genet 2005, 14(6):827-834.
    • (2005) Hum Mol Genet , vol.14 , Issue.6 , pp. 827-834
    • Zur, S.U.1    Schmidt, S.2    Kasper, B.3
  • 28
    • 84924707453 scopus 로고    scopus 로고
    • Failed CTL/NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time
    • Jenkins M.R., Rudd-Schmidt J.A., Lopez J.A., et al. Failed CTL/NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time. J Exp Med 2015, 212(3):307-317.
    • (2015) J Exp Med , vol.212 , Issue.3 , pp. 307-317
    • Jenkins, M.R.1    Rudd-Schmidt, J.A.2    Lopez, J.A.3
  • 29
    • 77955172764 scopus 로고    scopus 로고
    • Macrophage activation syndrome: advances towards understanding pathogenesis
    • Grom A.A., Mellins E.D. Macrophage activation syndrome: advances towards understanding pathogenesis. Curr Opin Rheumatol 2010, 22(5):561-566.
    • (2010) Curr Opin Rheumatol , vol.22 , Issue.5 , pp. 561-566
    • Grom, A.A.1    Mellins, E.D.2
  • 30
    • 1542283765 scopus 로고    scopus 로고
    • Natural killer cell dysfunction: A common pathway in systemic-onset juvenile rheumatoid arthritis, macrophage activation syndrome, and hemophagocytic lymphohistiocytosis?
    • Grom A.A. Natural killer cell dysfunction: A common pathway in systemic-onset juvenile rheumatoid arthritis, macrophage activation syndrome, and hemophagocytic lymphohistiocytosis?. Arthritis Rheum 2004, 50(3):689-698.
    • (2004) Arthritis Rheum , vol.50 , Issue.3 , pp. 689-698
    • Grom, A.A.1
  • 31
    • 0037338925 scopus 로고    scopus 로고
    • Natural killer cell dysfunction in patients with systemic-onset juvenile rheumatoid arthritis and macrophage activation syndrome
    • Grom A.A., Villanueva J., Lee S., et al. Natural killer cell dysfunction in patients with systemic-onset juvenile rheumatoid arthritis and macrophage activation syndrome. J Pediatr 2003, 142(3):292-296.
    • (2003) J Pediatr , vol.142 , Issue.3 , pp. 292-296
    • Grom, A.A.1    Villanueva, J.2    Lee, S.3
  • 32
    • 77950531755 scopus 로고    scopus 로고
    • Mutations in the perforin gene can be linked to macrophage activation syndrome in patients with systemic onset juvenile idiopathic arthritis
    • Vastert S.J., van W.R., D'Urbano L.E., et al. Mutations in the perforin gene can be linked to macrophage activation syndrome in patients with systemic onset juvenile idiopathic arthritis. Rheumatology (Oxford) 2010, 49(3):441-449.
    • (2010) Rheumatology (Oxford) , vol.49 , Issue.3 , pp. 441-449
    • Vastert, S.J.1    van, W.R.2    D'Urbano, L.E.3
  • 33
    • 21744452702 scopus 로고    scopus 로고
    • Natural killer cell dysfunction is a distinguishing feature of systemic onset juvenile rheumatoid arthritis and macrophage activation syndrome
    • Villanueva J., Lee S., Giannini E.H., et al. Natural killer cell dysfunction is a distinguishing feature of systemic onset juvenile rheumatoid arthritis and macrophage activation syndrome. Arthritis Res Ther 2005, 7(1):R30-R37.
    • (2005) Arthritis Res Ther , vol.7 , Issue.1 , pp. R30-R37
    • Villanueva, J.1    Lee, S.2    Giannini, E.H.3
  • 34
    • 39749185953 scopus 로고    scopus 로고
    • Mutations of the hemophagocytic lymphohistiocytosis-associated gene UNC13D in a patient with systemic juvenile idiopathic arthritis
    • Hazen M.M., Woodward A.L., Hofmann I., et al. Mutations of the hemophagocytic lymphohistiocytosis-associated gene UNC13D in a patient with systemic juvenile idiopathic arthritis. Arthritis Rheum 2008, 58(2):567-570.
    • (2008) Arthritis Rheum , vol.58 , Issue.2 , pp. 567-570
    • Hazen, M.M.1    Woodward, A.L.2    Hofmann, I.3
  • 35
    • 84905324940 scopus 로고    scopus 로고
    • Genetic defects in cytolysis in macrophage activation syndrome
    • Zhang M., Behrens E.M., Atkinson T.P., et al. Genetic defects in cytolysis in macrophage activation syndrome. Curr Rheumatol Rep 2014, 16(9):439.
    • (2014) Curr Rheumatol Rep , vol.16 , Issue.9 , pp. 439
    • Zhang, M.1    Behrens, E.M.2    Atkinson, T.P.3
  • 36
    • 84929642116 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis caused by dominant-negative mutations in STXBP2 that inhibit SNARE-mediated membrane fusion
    • Spessott W.A., Sanmillan M.L., McCormick M.E., et al. Hemophagocytic lymphohistiocytosis caused by dominant-negative mutations in STXBP2 that inhibit SNARE-mediated membrane fusion. Blood 2015, 125(10):1566-1577.
    • (2015) Blood , vol.125 , Issue.10 , pp. 1566-1577
    • Spessott, W.A.1    Sanmillan, M.L.2    McCormick, M.E.3
  • 37
    • 84857050020 scopus 로고    scopus 로고
    • Association of IRF5 polymorphisms with susceptibility to hemophagocytic lymphohistiocytosis in children
    • Yanagimachi M., Goto H., Miyamae T., et al. Association of IRF5 polymorphisms with susceptibility to hemophagocytic lymphohistiocytosis in children. J Clin Immunol 2011, 31(6):946-951.
    • (2011) J Clin Immunol , vol.31 , Issue.6 , pp. 946-951
    • Yanagimachi, M.1    Goto, H.2    Miyamae, T.3
  • 38
    • 84912047373 scopus 로고    scopus 로고
    • Whole-exome sequencing reveals overlap between macrophage activation syndrome in systemic juvenile idiopathic arthritis and familial hemophagocytic lymphohistiocytosis
    • Kaufman K.M., Linghu B., Szustakowski J.D., et al. Whole-exome sequencing reveals overlap between macrophage activation syndrome in systemic juvenile idiopathic arthritis and familial hemophagocytic lymphohistiocytosis. Arthritis Rheumatol 2014, 66(12):3486-3495.
    • (2014) Arthritis Rheumatol , vol.66 , Issue.12 , pp. 3486-3495
    • Kaufman, K.M.1    Linghu, B.2    Szustakowski, J.D.3
  • 39
    • 79957889288 scopus 로고    scopus 로고
    • Repeated TLR9 stimulation results in macrophage activation syndrome-like disease in mice
    • Behrens E.M., Canna S.W., Slade K., et al. Repeated TLR9 stimulation results in macrophage activation syndrome-like disease in mice. J Clin Invest 2011, 121(6):2264-2277.
    • (2011) J Clin Invest , vol.121 , Issue.6 , pp. 2264-2277
    • Behrens, E.M.1    Canna, S.W.2    Slade, K.3
  • 40
    • 3242752040 scopus 로고    scopus 로고
    • An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder
    • Jordan M.B., Hildeman D., Kappler J., et al. An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder. Blood 2004, 104(3):735-743.
    • (2004) Blood , vol.104 , Issue.3 , pp. 735-743
    • Jordan, M.B.1    Hildeman, D.2    Kappler, J.3
  • 41
    • 13544273826 scopus 로고    scopus 로고
    • Macrophage activation syndrome: characteristic findings on liver biopsy illustrating the key role of activated, IFN-gamma-producing lymphocytes and IL-6- and TNF-a-producing macrophages
    • Billiau A.D., Roskams T., Van Damme-Lombaerts R., et al. Macrophage activation syndrome: characteristic findings on liver biopsy illustrating the key role of activated, IFN-gamma-producing lymphocytes and IL-6- and TNF-a-producing macrophages. Blood 2005, 105(4):1648-1651.
    • (2005) Blood , vol.105 , Issue.4 , pp. 1648-1651
    • Billiau, A.D.1    Roskams, T.2    Van Damme-Lombaerts, R.3
  • 42
    • 0036746084 scopus 로고    scopus 로고
    • Highly elevated serum levels of interleukin-18 in systemic juvenile idiopathic arthritis but not in other juvenile idiopathic arthritis subtypes or in Kawasaki disease: comment on the article by Kawashima, et al
    • Maeno N., Takei S., Nomura Y., et al. Highly elevated serum levels of interleukin-18 in systemic juvenile idiopathic arthritis but not in other juvenile idiopathic arthritis subtypes or in Kawasaki disease: comment on the article by Kawashima, et al. Arthritis Rheum 2002, 46(9):2539-2541.
    • (2002) Arthritis Rheum , vol.46 , Issue.9 , pp. 2539-2541
    • Maeno, N.1    Takei, S.2    Nomura, Y.3
  • 43
    • 27744607629 scopus 로고    scopus 로고
    • Severe imbalance of IL-18/IL-18BP in patients with secondary hemophagocytic syndrome
    • Mazodier K., Marin V., Novick D., et al. Severe imbalance of IL-18/IL-18BP in patients with secondary hemophagocytic syndrome. Blood 2005, 106(10):3483-3489.
    • (2005) Blood , vol.106 , Issue.10 , pp. 3483-3489
    • Mazodier, K.1    Marin, V.2    Novick, D.3
  • 44
    • 84876730706 scopus 로고    scopus 로고
    • Pulmonary hypertension and other potentially fatal pulmonary complications in systemic juvenile idiopathic arthritis
    • Kimura Y., Weiss J.E., Haroldson K.L., et al. Pulmonary hypertension and other potentially fatal pulmonary complications in systemic juvenile idiopathic arthritis. Arthritis Care Res (Hoboken) 2013, 65(5):745-752.
    • (2013) Arthritis Care Res (Hoboken) , vol.65 , Issue.5 , pp. 745-752
    • Kimura, Y.1    Weiss, J.E.2    Haroldson, K.L.3
  • 45
    • 0036707740 scopus 로고    scopus 로고
    • Macrophage activation syndrome
    • Ravelli A. Macrophage activation syndrome. Curr Opin Rheumatol 2002, 14(5):548-552.
    • (2002) Curr Opin Rheumatol , vol.14 , Issue.5 , pp. 548-552
    • Ravelli, A.1
  • 46
    • 84879950624 scopus 로고    scopus 로고
    • Follistatin-like protein 1 and the ferritin/erythrocyte sedimentation rate ratio are potential biomarkers for dysregulated gene expression and macrophage activation syndrome in systemic juvenile idiopathic arthritis
    • Gorelik M., Fall N., Altaye M., et al. Follistatin-like protein 1 and the ferritin/erythrocyte sedimentation rate ratio are potential biomarkers for dysregulated gene expression and macrophage activation syndrome in systemic juvenile idiopathic arthritis. J Rheumatol 2013, 40(7):1191-1199.
    • (2013) J Rheumatol , vol.40 , Issue.7 , pp. 1191-1199
    • Gorelik, M.1    Fall, N.2    Altaye, M.3
  • 47
    • 79551691403 scopus 로고    scopus 로고
    • Hypocomplementemia associated with macrophage activation syndrome in systemic juvenile idiopathic arthritis and adult onset Still's disease: 3 cases
    • Gorelik M., Torok K.S., Kietz D.A., et al. Hypocomplementemia associated with macrophage activation syndrome in systemic juvenile idiopathic arthritis and adult onset Still's disease: 3 cases. J Rheumatol 2011, 38(2):396-397.
    • (2011) J Rheumatol , vol.38 , Issue.2 , pp. 396-397
    • Gorelik, M.1    Torok, K.S.2    Kietz, D.A.3
  • 48
    • 84880571708 scopus 로고    scopus 로고
    • Differentiating macrophage activation syndrome in systemic juvenile idiopathic arthritis from other forms of hemophagocytic lymphohistiocytosis
    • Lehmberg K., Pink I., Eulenburg C., et al. Differentiating macrophage activation syndrome in systemic juvenile idiopathic arthritis from other forms of hemophagocytic lymphohistiocytosis. J Pediatr 2013, 162(6):1245-1251.
    • (2013) J Pediatr , vol.162 , Issue.6 , pp. 1245-1251
    • Lehmberg, K.1    Pink, I.2    Eulenburg, C.3
  • 49
    • 34548359264 scopus 로고    scopus 로고
    • Recognition and management of macrophage activation syndrome in juvenile arthritis
    • Kelly A., Ramanan A.V. Recognition and management of macrophage activation syndrome in juvenile arthritis. Curr Opin Rheumatol 2007, 19(5):477-481.
    • (2007) Curr Opin Rheumatol , vol.19 , Issue.5 , pp. 477-481
    • Kelly, A.1    Ramanan, A.V.2
  • 50
    • 84871321221 scopus 로고    scopus 로고
    • Two randomized trials of canakinumab in systemic juvenile idiopathic arthritis
    • Ruperto N., Brunner H.I., Quartier P., et al. Two randomized trials of canakinumab in systemic juvenile idiopathic arthritis. N Engl J Med 2012, 367(25):2396-2406.
    • (2012) N Engl J Med , vol.367 , Issue.25 , pp. 2396-2406
    • Ruperto, N.1    Brunner, H.I.2    Quartier, P.3
  • 51
    • 84871318830 scopus 로고    scopus 로고
    • Randomized trial of tocilizumab in systemic juvenile idiopathic arthritis
    • De Benedetti F., Brunner H.I., Ruperto N., et al. Randomized trial of tocilizumab in systemic juvenile idiopathic arthritis. N Engl J Med 2012, 367(25):2385-2395.
    • (2012) N Engl J Med , vol.367 , Issue.25 , pp. 2385-2395
    • De Benedetti, F.1    Brunner, H.I.2    Ruperto, N.3
  • 52
    • 4344705888 scopus 로고    scopus 로고
    • Autologous stem cell transplantation for refractory juvenile idiopathic arthritis: analysis of clinical effects, mortality, and transplant related morbidity
    • De Kleer I.M., Brinkman D.M., Ferster A., et al. Autologous stem cell transplantation for refractory juvenile idiopathic arthritis: analysis of clinical effects, mortality, and transplant related morbidity. Ann Rheum Dis 2004, 63(10):1318-1326.
    • (2004) Ann Rheum Dis , vol.63 , Issue.10 , pp. 1318-1326
    • De Kleer, I.M.1    Brinkman, D.M.2    Ferster, A.3
  • 53
    • 40549129429 scopus 로고    scopus 로고
    • The paradox of macrophage activation syndrome triggered by biologic medications
    • Buoncompagni A., Loy A., Sala I., et al. The paradox of macrophage activation syndrome triggered by biologic medications. Pediatr Rheumatol Online J 2005, 3:70-73.
    • (2005) Pediatr Rheumatol Online J , vol.3 , pp. 70-73
    • Buoncompagni, A.1    Loy, A.2    Sala, I.3
  • 54
    • 79551654446 scopus 로고    scopus 로고
    • Anakinra as first-line disease-modifying therapy in systemic juvenile idiopathic arthritis: report of forty-six patients from an international multicenter series
    • Nigrovic P.A., Mannion M., Prince F.H., et al. Anakinra as first-line disease-modifying therapy in systemic juvenile idiopathic arthritis: report of forty-six patients from an international multicenter series. Arthritis Rheum 2011, 63(2):545-555.
    • (2011) Arthritis Rheum , vol.63 , Issue.2 , pp. 545-555
    • Nigrovic, P.A.1    Mannion, M.2    Prince, F.H.3
  • 55
    • 0029879812 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis. Report of 122 children from the International Registry. FHL Study Group of the Histiocyte Society
    • Arico M., Janka G., Fischer A., et al. Hemophagocytic lymphohistiocytosis. Report of 122 children from the International Registry. FHL Study Group of the Histiocyte Society. Leukemia 1996, 10(2):197-203.
    • (1996) Leukemia , vol.10 , Issue.2 , pp. 197-203
    • Arico, M.1    Janka, G.2    Fischer, A.3
  • 56
    • 84894448683 scopus 로고    scopus 로고
    • Marrow assessment for hemophagocytic lymphohistiocytosis demonstrates poor correlation with disease probability
    • Ho C., Yao X., Tian L., et al. Marrow assessment for hemophagocytic lymphohistiocytosis demonstrates poor correlation with disease probability. Am J Clin Pathol 2014, 141:62-71.
    • (2014) Am J Clin Pathol , vol.141 , pp. 62-71
    • Ho, C.1    Yao, X.2    Tian, L.3
  • 57
    • 84862139533 scopus 로고    scopus 로고
    • Toward the development of new diagnostic criteria for macrophage activation syndrome in systemic juvenile idiopathic arthritis
    • Davì S., Lattanzi B., Demirkaya E., et al. Toward the development of new diagnostic criteria for macrophage activation syndrome in systemic juvenile idiopathic arthritis. Ann Paediatr Rheumatol 2012, 1:1-7.
    • (2012) Ann Paediatr Rheumatol , vol.1 , pp. 1-7
    • Davì, S.1    Lattanzi, B.2    Demirkaya, E.3
  • 58
    • 0022642564 scopus 로고
    • Ferritinemia as an indicator of systemic disease activity in children with systemic juvenile rheumatoid arthritis
    • Pelkonen P., Swanljung K., Siimes M.A. Ferritinemia as an indicator of systemic disease activity in children with systemic juvenile rheumatoid arthritis. Acta Paediatr Scand 1986, 75(1):64-68.
    • (1986) Acta Paediatr Scand , vol.75 , Issue.1 , pp. 64-68
    • Pelkonen, P.1    Swanljung, K.2    Siimes, M.A.3
  • 59
    • 84908383447 scopus 로고    scopus 로고
    • Performance of current guidelines for diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis
    • Davi S., Minoia F., Pistorio A., et al. Performance of current guidelines for diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis. Arthritis Rheumatol 2014, 66(10):2871-2880.
    • (2014) Arthritis Rheumatol , vol.66 , Issue.10 , pp. 2871-2880
    • Davi, S.1    Minoia, F.2    Pistorio, A.3
  • 60
    • 79953309677 scopus 로고    scopus 로고
    • An international consensus survey of diagnostic criteria for macrophage activation syndrome in systemic juvenile idiopathic arthritis
    • Davi S., Consolaro A., Guseinova D., et al. An international consensus survey of diagnostic criteria for macrophage activation syndrome in systemic juvenile idiopathic arthritis. J Rheumatol 2011, 38(4):764-768.
    • (2011) J Rheumatol , vol.38 , Issue.4 , pp. 764-768
    • Davi, S.1    Consolaro, A.2    Guseinova, D.3
  • 61
    • 0030368747 scopus 로고    scopus 로고
    • Efficacy of cyclosporine A in the treatment of macrophage activation syndrome in juvenile arthritis: report of five cases
    • Mouy R., Stephan J.L., Pillet P., et al. Efficacy of cyclosporine A in the treatment of macrophage activation syndrome in juvenile arthritis: report of five cases. J Pediatr 1996, 129(5):750-754.
    • (1996) J Pediatr , vol.129 , Issue.5 , pp. 750-754
    • Mouy, R.1    Stephan, J.L.2    Pillet, P.3
  • 62
    • 0030044769 scopus 로고    scopus 로고
    • Macrophage activation syndrome in systemic juvenile rheumatoid arthritis successfully treated with cyclosporine
    • Ravelli A., De Benedetti F., Viola S., et al. Macrophage activation syndrome in systemic juvenile rheumatoid arthritis successfully treated with cyclosporine. J Pediatr 1996, 128(2):275-278.
    • (1996) J Pediatr , vol.128 , Issue.2 , pp. 275-278
    • Ravelli, A.1    De Benedetti, F.2    Viola, S.3
  • 63
    • 0034876361 scopus 로고    scopus 로고
    • Etanercept in the treatment of macrophage activation syndrome
    • Prahalad S., Bove K.E., Dickens D., et al. Etanercept in the treatment of macrophage activation syndrome. J Rheumatol 2001, 28(9):2120-2124.
    • (2001) J Rheumatol , vol.28 , Issue.9 , pp. 2120-2124
    • Prahalad, S.1    Bove, K.E.2    Dickens, D.3
  • 64
    • 0037311129 scopus 로고    scopus 로고
    • Macrophage activation syndrome following initiation of etanercept in a child with systemic onset juvenile rheumatoid arthritis
    • Ramanan A.V., Schneider R. Macrophage activation syndrome following initiation of etanercept in a child with systemic onset juvenile rheumatoid arthritis. J Rheumatol 2003, 30(2):401-403.
    • (2003) J Rheumatol , vol.30 , Issue.2 , pp. 401-403
    • Ramanan, A.V.1    Schneider, R.2
  • 65
    • 78751681576 scopus 로고    scopus 로고
    • Successful treatment of severe paediatric rheumatic disease-associated macrophage activation syndrome with interleukin-1 inhibition following conventional immunosuppressive therapy: case series with 12 patients
    • Miettunen P.M., Narendran A., Jayanthan A., et al. Successful treatment of severe paediatric rheumatic disease-associated macrophage activation syndrome with interleukin-1 inhibition following conventional immunosuppressive therapy: case series with 12 patients. Rheumatology (Oxford) 2011, 50(2):417-419.
    • (2011) Rheumatology (Oxford) , vol.50 , Issue.2 , pp. 417-419
    • Miettunen, P.M.1    Narendran, A.2    Jayanthan, A.3
  • 66
    • 78651365935 scopus 로고    scopus 로고
    • Rapid and sustained remission of systemic juvenile idiopathic arthritis-associated macrophage activation syndrome through treatment with anakinra and corticosteroids
    • Bruck N., Suttorp M., Kabus M., et al. Rapid and sustained remission of systemic juvenile idiopathic arthritis-associated macrophage activation syndrome through treatment with anakinra and corticosteroids. J Clin Rheumatol 2011, 17(1):23-27.
    • (2011) J Clin Rheumatol , vol.17 , Issue.1 , pp. 23-27
    • Bruck, N.1    Suttorp, M.2    Kabus, M.3
  • 67
    • 59149104561 scopus 로고    scopus 로고
    • A case of macrophage activation syndrome successfully treated with anakinra
    • Kelly A., Ramanan A.V. A case of macrophage activation syndrome successfully treated with anakinra. Nat Clin Pract Rheumatol 2008, 4(11):615-620.
    • (2008) Nat Clin Pract Rheumatol , vol.4 , Issue.11 , pp. 615-620
    • Kelly, A.1    Ramanan, A.V.2
  • 68
    • 35649001064 scopus 로고    scopus 로고
    • Macrophage activation syndrome (MAS) during anti-IL1 therapy (anakinra) in a patient affected by systemic juvenile arthritis (soJIA): a report and review of the literature
    • Lurati A., Teruzzi B., Salmaso A., et al. Macrophage activation syndrome (MAS) during anti-IL1 therapy (anakinra) in a patient affected by systemic juvenile arthritis (soJIA): a report and review of the literature. Pediatr Rheumatol Online J 2005, 3:79-85.
    • (2005) Pediatr Rheumatol Online J , vol.3 , pp. 79-85
    • Lurati, A.1    Teruzzi, B.2    Salmaso, A.3
  • 69
    • 67650866194 scopus 로고    scopus 로고
    • Anakinra for systemic juvenile arthritis: the Rocky Mountain experience
    • Zeft A., Hollister R., LaFleur B., et al. Anakinra for systemic juvenile arthritis: the Rocky Mountain experience. J Clin Rheumatol 2009, 15(4):161-164.
    • (2009) J Clin Rheumatol , vol.15 , Issue.4 , pp. 161-164
    • Zeft, A.1    Hollister, R.2    LaFleur, B.3
  • 70
    • 40749152243 scopus 로고    scopus 로고
    • Efficacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled, withdrawal phase III trial
    • Yokota S., Imagawa T., Mori M., et al. Efficacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled, withdrawal phase III trial. Lancet 2008, 371(9617):998-1006.
    • (2008) Lancet , vol.371 , Issue.9617 , pp. 998-1006
    • Yokota, S.1    Imagawa, T.2    Mori, M.3
  • 71
    • 79951948588 scopus 로고    scopus 로고
    • Benefit and a possible risk of tocilizumab therapy for adult-onset Still's disease accompanied by macrophage-activation syndrome
    • Kobayashi M., Takahashi Y., Yamashita H., et al. Benefit and a possible risk of tocilizumab therapy for adult-onset Still's disease accompanied by macrophage-activation syndrome. Mod Rheumatol 2011, 21(1):92-96.
    • (2011) Mod Rheumatol , vol.21 , Issue.1 , pp. 92-96
    • Kobayashi, M.1    Takahashi, Y.2    Yamashita, H.3
  • 72
    • 78650869495 scopus 로고    scopus 로고
    • Combination therapy of abatacept and anakinra in children with refractory systemic juvenile idiopathic arthritis: a retrospective case series
    • Record J.L., Beukelman T., Cron R.Q. Combination therapy of abatacept and anakinra in children with refractory systemic juvenile idiopathic arthritis: a retrospective case series. J Rheumatol 2011, 38(1):180-181.
    • (2011) J Rheumatol , vol.38 , Issue.1 , pp. 180-181
    • Record, J.L.1    Beukelman, T.2    Cron, R.Q.3
  • 73
    • 67349130863 scopus 로고    scopus 로고
    • Macrophage activation syndrome: serological markers and treatment with anti-thymocyte globulin
    • Coca A., Bundy K.W., Marston B., et al. Macrophage activation syndrome: serological markers and treatment with anti-thymocyte globulin. Clin Immunol 2009, 132(1):10-18.
    • (2009) Clin Immunol , vol.132 , Issue.1 , pp. 10-18
    • Coca, A.1    Bundy, K.W.2    Marston, B.3
  • 74
    • 34548384442 scopus 로고    scopus 로고
    • Immunotherapy of familial hemophagocytic lymphohistiocytosis with antithymocyte globulins: a single-center retrospective report of 38 patients
    • Mahlaoui N., Ouachee-Chardin M., de Saint B.G., et al. Immunotherapy of familial hemophagocytic lymphohistiocytosis with antithymocyte globulins: a single-center retrospective report of 38 patients. Pediatrics 2007, 120(3):e622-e628.
    • (2007) Pediatrics , vol.120 , Issue.3 , pp. e622-e628
    • Mahlaoui, N.1    Ouachee-Chardin, M.2    de Saint, B.G.3
  • 75
    • 80052616538 scopus 로고    scopus 로고
    • Efficacy and safety of repeat courses of rituximab treatment in patients with severe refractory juvenile idiopathic arthritis
    • Alexeeva E.I., Valieva S.I., Bzarova T.M., et al. Efficacy and safety of repeat courses of rituximab treatment in patients with severe refractory juvenile idiopathic arthritis. Clin Rheumatol 2011, 30(9):1163-1172.
    • (2011) Clin Rheumatol , vol.30 , Issue.9 , pp. 1163-1172
    • Alexeeva, E.I.1    Valieva, S.I.2    Bzarova, T.M.3
  • 76
    • 34548406426 scopus 로고    scopus 로고
    • Use of rituximab in conjunction with immunosuppressive chemotherapy as a novel therapy for Epstein Barr virus-associated hemophagocytic lymphohistiocytosis
    • Balamuth N.J., Nichols K.E., Paessler M., et al. Use of rituximab in conjunction with immunosuppressive chemotherapy as a novel therapy for Epstein Barr virus-associated hemophagocytic lymphohistiocytosis. J Pediatr Hematol Oncol 2007, 29(8):569-573.
    • (2007) J Pediatr Hematol Oncol , vol.29 , Issue.8 , pp. 569-573
    • Balamuth, N.J.1    Nichols, K.E.2    Paessler, M.3
  • 77
    • 70349687043 scopus 로고    scopus 로고
    • The role of rituximab in a case of EBV-related lymphoproliferative disease presenting with haemophagocytosis
    • Bosman G., Langemeijer S.M., Hebeda K.M., et al. The role of rituximab in a case of EBV-related lymphoproliferative disease presenting with haemophagocytosis. Neth J Med 2009, 67(8):364-365.
    • (2009) Neth J Med , vol.67 , Issue.8 , pp. 364-365
    • Bosman, G.1    Langemeijer, S.M.2    Hebeda, K.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.