Proton Pump Inhibitors Alter Specific Taxa in the Human Gastrointestinal Microbiome: A Crossover Trial

Gastroenterology

Volumn 149, Issue 4, 2015, Pages 883-885.e9

  Freedberg, Daniel E ^a   Toussaint, Nora C ^b   Chen, Sway P ^c   Ratner, Adam J ^a   Whittier, Susan ^d   Wang, Timothy C ^a   Wang, Harris H ^a,d   Abrams, Julian A ^a  

^a Howard Hughes Medical Institute   (United States)

^b NEW YORK GENOME CENTER   (United States)

^c Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain   (United States)

^d New York Presbyterian Morgan Stanley Children's Hospital   (United States)

Author keywords

Acid Suppression; Clostridium difficile Infection; Gastroesophageal Reflux Disease; Pharmacology

Indexed keywords

BILE ACID; OMEPRAZOLE; PROTON PUMP INHIBITOR; RNA 16S;

ADULT; ARTICLE; BACTERIAL OVERGROWTH; CLOSTRIDIALES; CLOSTRIDIUM DIFFICILE INFECTION; CONTROLLED STUDY; CROSSOVER PROCEDURE; ENTEROCOCCACEAE; FECES ANALYSIS; GENE SEQUENCE; HUMAN; HUMAN EXPERIMENT; INTESTINE FLORA; MICROCOCCACEAE; NONHUMAN; NORMAL HUMAN; OPEN STUDY; PATIENT COMPLIANCE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; STAPHYLOCOCCACEAE; STREPTOCOCCACEAE; TAXON; BACTERIUM; CHEMICALLY INDUCED; CLASSIFICATION; DRUG ADMINISTRATION; DRUG EFFECTS; FECES; GENETICS; INTESTINE; ISOLATION AND PURIFICATION; MICROBIOLOGY; MICROFLORA; PEPTOCLOSTRIDIUM DIFFICILE; PSEUDOMEMBRANOUS COLITIS; RIBOTYPING; RISK FACTOR; TIME FACTOR;

BACTERIA; CLOSTRIDIUM DIFFICILE; CROSS-OVER STUDIES; DRUG ADMINISTRATION SCHEDULE; ENTEROCOLITIS, PSEUDOMEMBRANOUS; FECES; HEALTHY VOLUNTEERS; HUMANS; INTESTINES; MICROBIOTA; OMEPRAZOLE; PROTON PUMP INHIBITORS; RIBOTYPING; RISK FACTORS; TIME FACTORS;

EID: 84942342601     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2015.06.043     Document Type: Article

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