-
1
-
-
79952795522
-
Alpha-Synuclein in Parkinson disease and other neurodegenerative disorders
-
1:CAS:528:DC%2BC3MXms1Wnu7g%3D 21342025
-
Eller M, Williams DR. alpha-Synuclein in Parkinson disease and other neurodegenerative disorders. Clin Chem Lab Med. 2011;49:403-8.
-
(2011)
Clin Chem Lab Med
, vol.49
, pp. 403-408
-
-
Eller, M.1
Williams, D.R.2
-
2
-
-
0032833653
-
Widespread alterations of alpha-synuclein in multiple system atrophy
-
1867032 1:CAS:528:DyaK1MXntFWmt7s%3D 10514406
-
Dickson DW, Liu W, Hardy J, Farrer M, Mehta N, Uitti R, et al. Widespread alterations of alpha-synuclein in multiple system atrophy. Am J Pathol. 1999;155:1241-51.
-
(1999)
Am J Pathol
, vol.155
, pp. 1241-1251
-
-
Dickson, D.W.1
Liu, W.2
Hardy, J.3
Farrer, M.4
Mehta, N.5
Uitti, R.6
Mark, M.7
Zimmerman, T.8
Golbe, L.9
Sage, J.10
-
3
-
-
0027930620
-
Clinical features and natural history of multiple system atrophy. An analysis of 100 cases
-
7922469
-
Wenning GK, Ben Shlomo Y, Magalhaes M, Daniel SE, Quinn NP. Clinical features and natural history of multiple system atrophy. An analysis of 100 cases. Brain. 1994;117(Pt 4):835-45.
-
(1994)
Brain
, vol.117
, pp. 835-845
-
-
Wenning, G.K.1
Ben Shlomo, Y.2
Magalhaes, M.3
Daniel, S.E.4
Quinn, N.P.5
-
4
-
-
0028087201
-
Cellular pathology of multiple system atrophy: A review
-
1072436 1:STN:280:DyaK2c7nt1ektg%3D%3D 8126492
-
Lantos PL, Papp MI. Cellular pathology of multiple system atrophy: a review. J Neurol Neurosurg Psychiatry. 1994;57:129-33.
-
(1994)
J Neurol Neurosurg Psychiatry
, vol.57
, pp. 129-133
-
-
Lantos, P.L.1
Papp, M.I.2
-
5
-
-
0024843373
-
Glial cytoplasmic inclusions in the CNS of patients with multiple system atrophy (striatonigral degeneration, olivopontocerebellar atrophy and Shy-Drager syndrome)
-
1:STN:280:DyaK3c7jt1OrtA%3D%3D 2559165
-
Papp MI, Kahn JE, Lantos PL. Glial cytoplasmic inclusions in the CNS of patients with multiple system atrophy (striatonigral degeneration, olivopontocerebellar atrophy and Shy-Drager syndrome). J Neurol Sci. 1989;94:79-100.
-
(1989)
J Neurol Sci
, vol.94
, pp. 79-100
-
-
Papp, M.I.1
Kahn, J.E.2
Lantos, P.L.3
-
6
-
-
84884250340
-
The function of alpha-synuclein
-
1:CAS:528:DC%2BC3sXhsVOkt7fK 24050397
-
Bendor JT, Logan TP, Edwards RH. The function of alpha-synuclein. Neuron. 2013;79:1044-66.
-
(2013)
Neuron
, vol.79
, pp. 1044-1066
-
-
Bendor, J.T.1
Logan, T.P.2
Edwards, R.H.3
-
7
-
-
84899889312
-
Accumulation of oligomer-prone alpha-synuclein exacerbates synaptic and neuronal degeneration in vivo
-
3999721 24662516
-
Rockenstein E, Nuber S, Overk CR, Ubhi K, Mante M, Patrick C, et al. Accumulation of oligomer-prone alpha-synuclein exacerbates synaptic and neuronal degeneration in vivo. Brain. 2014;137:1496-513.
-
(2014)
Brain
, vol.137
, pp. 1496-1513
-
-
Rockenstein, E.1
Nuber, S.2
Overk, C.R.3
Ubhi, K.4
Mante, M.5
Patrick, C.6
Adame, A.7
Trejo-Morales, M.8
Gerez, J.9
Picotti, P.10
-
8
-
-
84893642253
-
Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases
-
4011661 1:CAS:528:DC%2BC2cXitVenu7s%3D 24504409
-
Guo JL, Lee VM. Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases. Nat Med. 2014;20:130-8.
-
(2014)
Nat Med
, vol.20
, pp. 130-138
-
-
Guo, J.L.1
Lee, V.M.2
-
9
-
-
44749083979
-
Assembly-dependent endocytosis and clearance of extracellular alpha-synuclein
-
1:CAS:528:DC%2BD1cXnsF2mtrk%3D 18291704
-
Lee HJ, Suk JE, Bae EJ, Lee JH, Paik SR, Lee SJ. Assembly-dependent endocytosis and clearance of extracellular alpha-synuclein. Int J Biochem Cell Biol. 2008;40:1835-49.
-
(2008)
Int J Biochem Cell Biol
, vol.40
, pp. 1835-1849
-
-
Lee, H.J.1
Suk, J.E.2
Bae, E.J.3
Lee, J.H.4
Paik, S.R.5
Lee, S.J.6
-
10
-
-
84888349390
-
Transmission of multiple system atrophy prions to transgenic mice
-
3845125 1:CAS:528:DC%2BC3sXhvFemurnM 24218576
-
Watts JC, Giles K, Oehler A, Middleton L, Dexter DT, Gentleman SM, et al. Transmission of multiple system atrophy prions to transgenic mice. Proc Natl Acad Sci U S A. 2013;110:19555-60.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 19555-19560
-
-
Watts, J.C.1
Giles, K.2
Oehler, A.3
Middleton, L.4
Dexter, D.T.5
Gentleman, S.M.6
Dearmond, S.J.7
Prusiner, S.B.8
-
11
-
-
78649907008
-
Cell-to-cell transmission of non-prion protein aggregates
-
21045796
-
Lee SJ, Desplats P, Sigurdson C, Tsigelny I, Masliah E. Cell-to-cell transmission of non-prion protein aggregates. Nature reviews Neurology. 2010;6:702-6.
-
(2010)
Nature Reviews Neurology
, vol.6
, pp. 702-706
-
-
Lee, S.J.1
Desplats, P.2
Sigurdson, C.3
Tsigelny, I.4
Masliah, E.5
-
12
-
-
84898046790
-
Alpha-synuclein mRNA expression in oligodendrocytes in MSA
-
4238782 24590631
-
Asi YT, Simpson JE, Heath PR, Wharton SB, Lees AJ, Revesz T, et al. Alpha-synuclein mRNA expression in oligodendrocytes in MSA. Glia. 2014;62:964-70.
-
(2014)
Glia
, vol.62
, pp. 964-970
-
-
Asi, Y.T.1
Simpson, J.E.2
Heath, P.R.3
Wharton, S.B.4
Lees, A.J.5
Revesz, T.6
Houlden, H.7
Holton, J.L.8
-
13
-
-
84891836634
-
The role of glia in alpha-synucleinopathies
-
3589649 1:CAS:528:DC%2BC3sXjsFejsbg%3D 22941028
-
Fellner L, Stefanova N. The role of glia in alpha-synucleinopathies. Molecular neurobiology. 2013;47:575-86.
-
(2013)
Molecular Neurobiology
, vol.47
, pp. 575-586
-
-
Fellner, L.1
Stefanova, N.2
-
14
-
-
77956194977
-
Alpha-synuclein activates microglia by inducing the expressions of matrix metalloproteinases and the subsequent activation of protease-activated receptor-1
-
1:CAS:528:DC%2BC3cXns1Cqtrs%3D 20511551
-
Lee EJ, Woo MS, Moon PG, Baek MC, Choi IY, Kim WK, et al. Alpha-synuclein activates microglia by inducing the expressions of matrix metalloproteinases and the subsequent activation of protease-activated receptor-1. J Immunol. 2010;185:615-23.
-
(2010)
J Immunol
, vol.185
, pp. 615-623
-
-
Lee, E.J.1
Woo, M.S.2
Moon, P.G.3
Baek, M.C.4
Choi, I.Y.5
Kim, W.K.6
Junn, E.7
Kim, H.S.8
-
15
-
-
77957371012
-
Alpha-synuclein stimulation of astrocytes: Potential role for neuroinflammation and neuroprotection
-
2952089 20972375
-
Lee HJ, Kim C, Lee SJ. Alpha-synuclein stimulation of astrocytes: Potential role for neuroinflammation and neuroprotection. Oxidative medicine and cellular longevity. 2010;3:283-7.
-
(2010)
Oxidative Medicine and Cellular Longevity
, vol.3
, pp. 283-287
-
-
Lee, H.J.1
Kim, C.2
Lee, S.J.3
-
16
-
-
0033828258
-
Localization of a novel type trypsin-like serine protease, neurosin, in brain tissues of Alzheimer's disease and Parkinson's disease
-
1:CAS:528:DC%2BD3cXmvFKmurw%3D 10997858
-
Ogawa K, Yamada T, Tsujioka Y, Taguchi J, Takahashi M, Tsuboi Y, et al. Localization of a novel type trypsin-like serine protease, neurosin, in brain tissues of Alzheimer's disease and Parkinson's disease. Psychiatry Clin Neurosci. 2000;54:419-26.
-
(2000)
Psychiatry Clin Neurosci
, vol.54
, pp. 419-426
-
-
Ogawa, K.1
Yamada, T.2
Tsujioka, Y.3
Taguchi, J.4
Takahashi, M.5
Tsuboi, Y.6
Fujino, Y.7
Nakajima, M.8
Yamamoto, T.9
Akatsu, H.10
-
17
-
-
0142154275
-
Alpha-synuclein degradation by serine protease neurosin: Implication for pathogenesis of synucleinopathies
-
1:CAS:528:DC%2BD3sXot1Cqt7g%3D
-
Iwata A, Maruyama M, Akagi T, Hashikawa T, Kanazawa I, Tsuji S, et al. Alpha-synuclein degradation by serine protease neurosin: implication for pathogenesis of synucleinopathies. Human Mol Genet. 2003;12:2625-35.
-
(2003)
Human Mol Genet
, vol.12
, pp. 2625-2635
-
-
Iwata, A.1
Maruyama, M.2
Akagi, T.3
Hashikawa, T.4
Kanazawa, I.5
Tsuji, S.6
Nukina, N.7
-
18
-
-
77955686287
-
Extracellular neurosin degrades alpha-synuclein in cultured cells
-
1:CAS:528:DC%2BC3cXos1ygu7s%3D 20403393
-
Tatebe H, Watanabe Y, Kasai T, Mizuno T, Nakagawa M, Tanaka M, et al. Extracellular neurosin degrades alpha-synuclein in cultured cells. Neurosci Res. 2010;67:341-6.
-
(2010)
Neurosci Res
, vol.67
, pp. 341-346
-
-
Tatebe, H.1
Watanabe, Y.2
Kasai, T.3
Mizuno, T.4
Nakagawa, M.5
Tanaka, M.6
Tokuda, T.7
-
19
-
-
41749115922
-
Cleavage of normal and pathological forms of alpha-synuclein by neurosin in vitro
-
1:CAS:528:DC%2BD1cXks1art70%3D 18358605
-
Kasai T, Tokuda T, Yamaguchi N, Watanabe Y, Kametani F, Nakagawa M, et al. Cleavage of normal and pathological forms of alpha-synuclein by neurosin in vitro. Neurosci Lett. 2008;436:52-6.
-
(2008)
Neurosci Lett
, vol.436
, pp. 52-56
-
-
Kasai, T.1
Tokuda, T.2
Yamaguchi, N.3
Watanabe, Y.4
Kametani, F.5
Nakagawa, M.6
Mizuno, T.7
-
20
-
-
0034783206
-
The spectrum of human kallikrein 6 (zyme/protease M/neurosin) expression in human tissues as assessed by immunohistochemistry
-
1:CAS:528:DC%2BD3MXotVWisrc%3D 11668196
-
Petraki CD, Karavana VN, Skoufogiannis PT, Little SP, Howarth DJ, Yousef GM, et al. The spectrum of human kallikrein 6 (zyme/protease M/neurosin) expression in human tissues as assessed by immunohistochemistry. J Histochem Cytochem. 2001;49:1431-41.
-
(2001)
J Histochem Cytochem
, vol.49
, pp. 1431-1441
-
-
Petraki, C.D.1
Karavana, V.N.2
Skoufogiannis, P.T.3
Little, S.P.4
Howarth, D.J.5
Yousef, G.M.6
Diamandis, E.P.7
-
21
-
-
0032744127
-
Protease M/neurosin mRNA is expressed in mature oligodendrocytes
-
1:CAS:528:DyaK1MXmslehtbs%3D 10521576
-
Yamanaka H, He X, Matsumoto K, Shiosaka S, Yoshida S. Protease M/neurosin mRNA is expressed in mature oligodendrocytes. Brain Res Mol Brain Res. 1999;71:217-24.
-
(1999)
Brain Res Mol Brain Res
, vol.71
, pp. 217-224
-
-
Yamanaka, H.1
He, X.2
Matsumoto, K.3
Shiosaka, S.4
Yoshida, S.5
-
22
-
-
15444352446
-
Zyme, a novel and potentially amyloidogenic enzyme cDNA isolated from Alzheimer's disease brain
-
1:CAS:528:DyaK2sXms1ehsLg%3D 9312124
-
Little SP, Dixon EP, Norris F, Buckley W, Becker GW, Johnson M, et al. Zyme, a novel and potentially amyloidogenic enzyme cDNA isolated from Alzheimer's disease brain. J Biol Chem. 1997;272:25135-42.
-
(1997)
J Biol Chem
, vol.272
, pp. 25135-25142
-
-
Little, S.P.1
Dixon, E.P.2
Norris, F.3
Buckley, W.4
Becker, G.W.5
Johnson, M.6
Dobbins, J.R.7
Wyrick, T.8
Miller, J.R.9
Mackellar, W.10
-
23
-
-
84872189834
-
Low CSF levels of both alpha-synuclein and the alpha-synuclein cleaving enzyme neurosin in patients with synucleinopathy
-
3540093 23308173
-
Wennstrom M, Surova Y, Hall S, Nilsson C, Minthon L, Bostrom F, et al. Low CSF levels of both alpha-synuclein and the alpha-synuclein cleaving enzyme neurosin in patients with synucleinopathy. PLoS One. 2013;8:e53250.
-
(2013)
PLoS One
, vol.8
, pp. e53250
-
-
Wennstrom, M.1
Surova, Y.2
Hall, S.3
Nilsson, C.4
Minthon, L.5
Bostrom, F.6
Hansson, O.7
Nielsen, H.M.8
-
24
-
-
84965084989
-
Accumulation of inverted question mark-synuclein in dementia with Lewy bodies is associated with decline in the inverted question mark-synuclein-degrading enzymes kallikrein-6 and calpain-1
-
4271448 25476568
-
Miners J, Renfrew R, Swirski M, Love S. Accumulation of inverted question mark-synuclein in dementia with Lewy bodies is associated with decline in the inverted question mark-synuclein-degrading enzymes kallikrein-6 and calpain-1. Acta Neuropathol Commun. 2014;2:164.
-
(2014)
Acta Neuropathol Commun
, vol.2
, pp. 164
-
-
Miners, J.1
Renfrew, R.2
Swirski, M.3
Love, S.4
-
25
-
-
84871921645
-
Lentivirus mediated delivery of neurosin promotes clearance of wild-type alpha-synuclein and reduces the pathology in an alpha-synuclein model of LBD
-
3538325 1:CAS:528:DC%2BC38Xls1Wkurw%3D 22508489
-
Spencer B, Michael S, Shen J, Kosberg K, Rockenstein E, Patrick C, et al. Lentivirus mediated delivery of neurosin promotes clearance of wild-type alpha-synuclein and reduces the pathology in an alpha-synuclein model of LBD. Mol Ther. 2013;21:31-41.
-
(2013)
Mol Ther
, vol.21
, pp. 31-41
-
-
Spencer, B.1
Michael, S.2
Shen, J.3
Kosberg, K.4
Rockenstein, E.5
Patrick, C.6
Adame, A.7
Masliah, E.8
-
26
-
-
3242786608
-
Human kallikrein 6 activity is regulated via an autoproteolytic mechanism of activation/inactivation
-
1:CAS:528:DC%2BD2cXlslaitr8%3D 15255184
-
Bayes A, Tsetsenis T, Ventura S, Vendrell J, Aviles FX, Sotiropoulou G. Human kallikrein 6 activity is regulated via an autoproteolytic mechanism of activation/inactivation. Biol Chem. 2004;385:517-24.
-
(2004)
Biol Chem
, vol.385
, pp. 517-524
-
-
Bayes, A.1
Tsetsenis, T.2
Ventura, S.3
Vendrell, J.4
Aviles, F.X.5
Sotiropoulou, G.6
-
27
-
-
27944436033
-
Neurological and neurodegenerative alterations in a transgenic mouse model expressing human alpha-synuclein under oligodendrocyte promoter: Implications for multiple system atrophy
-
1:CAS:528:DC%2BD2MXht1KqsbzP 16291942
-
Shults CW, Rockenstein E, Crews L, Adame A, Mante M, Larrea G, et al. Neurological and neurodegenerative alterations in a transgenic mouse model expressing human alpha-synuclein under oligodendrocyte promoter: implications for multiple system atrophy. J Neurosci. 2005;25:10689-99.
-
(2005)
J Neurosci
, vol.25
, pp. 10689-10699
-
-
Shults, C.W.1
Rockenstein, E.2
Crews, L.3
Adame, A.4
Mante, M.5
Larrea, G.6
Hashimoto, M.7
Song, D.8
Iwatsubo, T.9
Tsuboi, K.10
Masliah, E.11
-
28
-
-
77958553537
-
Neurodegeneration in a transgenic mouse model of multiple system atrophy is associated with altered expression of oligodendroglial-derived neurotrophic factors
-
2896284 1:CAS:528:DC%2BC3cXovVWmsLg%3D 20445049
-
Ubhi K, Rockenstein E, Mante M, Inglis C, Adame A, Patrick C, et al. Neurodegeneration in a transgenic mouse model of multiple system atrophy is associated with altered expression of oligodendroglial-derived neurotrophic factors. J Neurosci. 2010;30:6236-46.
-
(2010)
J Neurosci
, vol.30
, pp. 6236-6246
-
-
Ubhi, K.1
Rockenstein, E.2
Mante, M.3
Inglis, C.4
Adame, A.5
Patrick, C.6
Whitney, K.7
Masliah, E.8
-
29
-
-
84926209020
-
ESCRT-mediated uptake and degradation of brain-targeted alpha-synuclein single chain antibody attenuates neuronal degeneration in vivo
-
4428402 1:CAS:528:DC%2BC2cXhtlaru7jF 25008355
-
Spencer B, Emadi S, Desplats P, Eleuteri S, Michael S, Kosberg K, et al. ESCRT-mediated uptake and degradation of brain-targeted alpha-synuclein single chain antibody attenuates neuronal degeneration in vivo. Mol Ther. 2014;22:1753-67.
-
(2014)
Mol Ther
, vol.22
, pp. 1753-1767
-
-
Spencer, B.1
Emadi, S.2
Desplats, P.3
Eleuteri, S.4
Michael, S.5
Kosberg, K.6
Shen, J.7
Rockenstein, E.8
Patrick, C.9
Adame, A.10
-
30
-
-
79551635864
-
Peripheral delivery of a CNS targeted, metalo-protease reduces abeta toxicity in a mouse model of Alzheimer's disease
-
e16575 3031588 1:CAS:528:DC%2BC3MXhvFahtLo%3D 21304989
-
Spencer B, Marr RA, Gindi R, Potkar R, Michael S, Adame A, et al. Peripheral delivery of a CNS targeted, metalo-protease reduces abeta toxicity in a mouse model of Alzheimer's disease. PLoS One. 2011;6, e16575.
-
(2011)
PLoS One
, vol.6
-
-
Spencer, B.1
Marr, R.A.2
Gindi, R.3
Potkar, R.4
Michael, S.5
Adame, A.6
Rockenstein, E.7
Verma, I.M.8
Masliah, E.9
-
31
-
-
84903449630
-
A Neuroprotective Brain Penetrating Endopeptidase Fusion Protein Ameliorates Alzheimer's Disease Pathology and Restores Neurogenesis
-
4067222 1:CAS:528:DC%2BC2cXhtVaisrvI 24825898
-
Spencer B, Verma I, Desplats P, Morvinski D, Rockenstein E, Adame A, et al. A Neuroprotective Brain Penetrating Endopeptidase Fusion Protein Ameliorates Alzheimer's Disease Pathology and Restores Neurogenesis. J Biol Chem. 2014;289(25):17917-31.
-
(2014)
J Biol Chem
, vol.289
, Issue.25
, pp. 17917-17931
-
-
Spencer, B.1
Verma, I.2
Desplats, P.3
Morvinski, D.4
Rockenstein, E.5
Adame, A.6
Masliah, E.7
-
32
-
-
34250665873
-
Targeted delivery of proteins across the blood-brain barrier
-
1857226 1:CAS:528:DC%2BD2sXlslWqtLk%3D 17463083
-
Spencer BJ, Verma IM. Targeted delivery of proteins across the blood-brain barrier. Proc Natl Acad Sci U S A. 2007;104(18):7594-9.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, Issue.18
, pp. 7594-7599
-
-
Spencer, B.J.1
Verma, I.M.2
-
33
-
-
0032802253
-
The mammalian low-density lipoprotein receptor family
-
1:CAS:528:DyaK1MXlt1ejs7c%3D 10448520
-
Hussain MM, Strickland DK, Bakillah A. The mammalian low-density lipoprotein receptor family. Annu Rev Nutr. 1999;19:141-72.
-
(1999)
Annu Rev Nutr
, vol.19
, pp. 141-172
-
-
Hussain, M.M.1
Strickland, D.K.2
Bakillah, A.3
-
34
-
-
37049030172
-
Novel strategies for Alzheimer's disease treatment
-
1:CAS:528:DC%2BD2sXhtlClsLfO 18034651
-
Spencer B, Rockenstein E, Crews L, Marr R, Masliah E. Novel strategies for Alzheimer's disease treatment. Expert Opin Biol Ther. 2007;7:1853-67.
-
(2007)
Expert Opin Biol Ther
, vol.7
, pp. 1853-1867
-
-
Spencer, B.1
Rockenstein, E.2
Crews, L.3
Marr, R.4
Masliah, E.5
-
35
-
-
84890140306
-
Antidepressants reduce neuroinflammatory responses and astroglial alpha-synuclein accumulation in a transgenic mouse model of multiple system atrophy
-
4183229 24310907
-
Valera E, Ubhi K, Mante M, Rockenstein E, Masliah E. Antidepressants reduce neuroinflammatory responses and astroglial alpha-synuclein accumulation in a transgenic mouse model of multiple system atrophy. Glia. 2014;62:317-37.
-
(2014)
Glia
, vol.62
, pp. 317-337
-
-
Valera, E.1
Ubhi, K.2
Mante, M.3
Rockenstein, E.4
Masliah, E.5
-
36
-
-
0031683914
-
Myelin degeneration in multiple system atrophy detected by unique antibodies
-
1853025 1:CAS:528:DyaK1cXmtFKnurk%3D 9736024
-
Matsuo A, Akiguchi I, Lee GC, McGeer EG, McGeer PL, Kimura J. Myelin degeneration in multiple system atrophy detected by unique antibodies. Am J Pathol. 1998;153:735-44.
-
(1998)
Am J Pathol
, vol.153
, pp. 735-744
-
-
Matsuo, A.1
Akiguchi, I.2
Lee, G.C.3
McGeer, E.G.4
McGeer, P.L.5
Kimura, J.6
-
37
-
-
23944454481
-
Process outgrowth in oligodendrocytes is mediated by CNP, a novel microtubule assembly myelin protein
-
2171497 1:CAS:528:DC%2BD2MXosVaku78%3D 16103231
-
Lee J, Gravel M, Zhang R, Thibault P, Braun PE. Process outgrowth in oligodendrocytes is mediated by CNP, a novel microtubule assembly myelin protein. J Cell Biol. 2005;170:661-73.
-
(2005)
J Cell Biol
, vol.170
, pp. 661-673
-
-
Lee, J.1
Gravel, M.2
Zhang, R.3
Thibault, P.4
Braun, P.E.5
-
38
-
-
84862762387
-
Systemic proteasome inhibition triggers neurodegeneration in a transgenic mouse model expressing human alpha-synuclein under oligodendrocyte promoter: Implications for multiple system atrophy
-
3377902 1:CAS:528:DC%2BC38XovFarsrw%3D 22491959
-
Stefanova N, Kaufmann WA, Humpel C, Poewe W, Wenning GK. Systemic proteasome inhibition triggers neurodegeneration in a transgenic mouse model expressing human alpha-synuclein under oligodendrocyte promoter: implications for multiple system atrophy. Acta Neuropathol. 2012;124:51-65.
-
(2012)
Acta Neuropathol
, vol.124
, pp. 51-65
-
-
Stefanova, N.1
Kaufmann, W.A.2
Humpel, C.3
Poewe, W.4
Wenning, G.K.5
-
39
-
-
84942292582
-
Cognitive impairments in multiple system atrophy of the cerebellar type
-
4027711 24868391
-
Hong HJ, Song SK, Lee PH, Sohn YH, Lee JE. Cognitive impairments in multiple system atrophy of the cerebellar type. J Mov Disord. 2011;4:41-5.
-
(2011)
J Mov Disord
, vol.4
, pp. 41-45
-
-
Hong, H.J.1
Song, S.K.2
Lee, P.H.3
Sohn, Y.H.4
Lee, J.E.5
-
40
-
-
84924977160
-
Kallikrein-related peptidase 5 induces miRNA-mediated anti-oncogenic pathways in breast cancer
-
4278268 25593998
-
Sidiropoulos KG, White NM, Bui A, Ding Q, Boulos P, Pampalakis G, et al. Kallikrein-related peptidase 5 induces miRNA-mediated anti-oncogenic pathways in breast cancer. Oncoscience. 2014;1:709-24.
-
(2014)
Oncoscience
, vol.1
, pp. 709-724
-
-
Sidiropoulos, K.G.1
White, N.M.2
Bui, A.3
Ding, Q.4
Boulos, P.5
Pampalakis, G.6
Khella, H.7
Samuel, J.N.8
Sotiropoulou, G.9
Yousef, G.M.10
-
41
-
-
84901218389
-
The KLK5 protease suppresses breast cancer by repressing the mevalonate pathway
-
4058013 24158494
-
Pampalakis G, Obasuyi O, Papadodima O, Chatziioannou A, Zoumpourlis V, Sotiropoulou G. The KLK5 protease suppresses breast cancer by repressing the mevalonate pathway. Oncotarget. 2014;5:2390-403.
-
(2014)
Oncotarget
, vol.5
, pp. 2390-2403
-
-
Pampalakis, G.1
Obasuyi, O.2
Papadodima, O.3
Chatziioannou, A.4
Zoumpourlis, V.5
Sotiropoulou, G.6
-
42
-
-
33646011568
-
Characterization of proteinase-activated receptor 2 signalling and expression in rat hippocampal neurons and astrocytes
-
1:CAS:528:DC%2BD28Xjs1KmtLs%3D 16430928
-
Bushell TJ, Plevin R, Cobb S, Irving AJ. Characterization of proteinase-activated receptor 2 signalling and expression in rat hippocampal neurons and astrocytes. Neuropharmacology. 2006;50:714-25.
-
(2006)
Neuropharmacology
, vol.50
, pp. 714-725
-
-
Bushell, T.J.1
Plevin, R.2
Cobb, S.3
Irving, A.J.4
-
43
-
-
34248141719
-
The emergence of proteinase-activated receptor-2 as a novel target for the treatment of inflammation-related CNS disorders
-
2075212 1:CAS:528:DC%2BD2sXls1Kht7s%3D 17347265
-
Bushell T. The emergence of proteinase-activated receptor-2 as a novel target for the treatment of inflammation-related CNS disorders. J Physiol. 2007;581:7-16.
-
(2007)
J Physiol
, vol.581
, pp. 7-16
-
-
Bushell, T.1
-
44
-
-
33746878256
-
Implications of protease M/neurosin in myelination during experimental demyelination and remyelination
-
1:CAS:528:DC%2BD28XotV2mtbs%3D 16890353
-
Bando Y, Ito S, Nagai Y, Terayama R, Kishibe M, Jiang YP, et al. Implications of protease M/neurosin in myelination during experimental demyelination and remyelination. Neurosci Lett. 2006;405:175-80.
-
(2006)
Neurosci Lett
, vol.405
, pp. 175-180
-
-
Bando, Y.1
Ito, S.2
Nagai, Y.3
Terayama, R.4
Kishibe, M.5
Jiang, Y.P.6
Mitrovic, B.7
Takahashi, T.8
Yoshida, S.9
-
45
-
-
84874344595
-
In vivo analysis of kallikrein-related peptidase 6 (KLK6) function in oligodendrocyte development and the expression of myelin proteins
-
1:CAS:528:DC%2BC3sXkt12rurg%3D 23376368
-
Murakami K, Jiang YP, Tanaka T, Bando Y, Mitrovic B, Yoshida S. In vivo analysis of kallikrein-related peptidase 6 (KLK6) function in oligodendrocyte development and the expression of myelin proteins. Neuroscience. 2013;236:1-11.
-
(2013)
Neuroscience
, vol.236
, pp. 1-11
-
-
Murakami, K.1
Jiang, Y.P.2
Tanaka, T.3
Bando, Y.4
Mitrovic, B.5
Yoshida, S.6
-
46
-
-
84866679781
-
Antibody-aided clearance of extracellular alpha-synuclein prevents cell-to-cell aggregate transmission
-
3752153 1:CAS:528:DC%2BC38XhsVKhsrzK 23015436
-
Bae EJ, Lee HJ, Rockenstein E, Ho DH, Park EB, Yang NY, et al. Antibody-aided clearance of extracellular alpha-synuclein prevents cell-to-cell aggregate transmission. J Neurosci. 2012;32:13454-69.
-
(2012)
J Neurosci
, vol.32
, pp. 13454-13469
-
-
Bae, E.J.1
Lee, H.J.2
Rockenstein, E.3
Ho, D.H.4
Park, E.B.5
Yang, N.Y.6
Desplats, P.7
Masliah, E.8
Lee, S.J.9
-
47
-
-
44749090147
-
Clearance and deposition of extracellular alpha-synuclein aggregates in microglia
-
1:CAS:528:DC%2BD1cXnt1OrurY%3D 18492487
-
Lee HJ, Suk JE, Bae EJ, Lee SJ. Clearance and deposition of extracellular alpha-synuclein aggregates in microglia. Biochem Biophys Res Commun. 2008;372:423-8.
-
(2008)
Biochem Biophys Res Commun
, vol.372
, pp. 423-428
-
-
Lee, H.J.1
Suk, J.E.2
Bae, E.J.3
Lee, S.J.4
-
48
-
-
84928533692
-
Active immunization against alpha-synuclein ameliorates the degenerative pathology and prevents demyelination in a model of multiple system atrophy
-
4411775 25886309
-
Mandler M, Valera E, Rockenstein E, Mante M, Weninger H, Patrick C, et al. Active immunization against alpha-synuclein ameliorates the degenerative pathology and prevents demyelination in a model of multiple system atrophy. Mol Neurodegener. 2015;10:10.
-
(2015)
Mol Neurodegener
, vol.10
, pp. 10
-
-
Mandler, M.1
Valera, E.2
Rockenstein, E.3
Mante, M.4
Weninger, H.5
Patrick, C.6
Adame, A.7
Schmidhuber, S.8
Santic, R.9
Schneeberger, A.10
-
49
-
-
84924244777
-
The degree of astrocyte activation in multiple system atrophy is inversely proportional to the distance to alpha-synuclein inclusions
-
1:CAS:528:DC%2BC2MXjs1Olt70%3D 25731829
-
Radford R, Rcom-H'cheo-Gauthier A, Wong MB, Eaton ED, Quilty M, Blizzard C, et al. The degree of astrocyte activation in multiple system atrophy is inversely proportional to the distance to alpha-synuclein inclusions. Mol Cell Neurosci. 2015;65:68-81.
-
(2015)
Mol Cell Neurosci
, vol.65
, pp. 68-81
-
-
Radford, R.1
Rcom-H'Cheo-Gauthier, A.2
Wong, M.B.3
Eaton, E.D.4
Quilty, M.5
Blizzard, C.6
Norazit, A.7
Meedeniya, A.8
Vickers, J.C.9
Gai, W.P.10
-
50
-
-
84859980871
-
Low-density lipoprotein receptor represents an apolipoprotein E-independent pathway of Abeta uptake and degradation by astrocytes
-
3340151 1:CAS:528:DC%2BC38XlvVGltr0%3D 22383525
-
Basak JM, Verghese PB, Yoon H, Kim J, Holtzman DM. Low-density lipoprotein receptor represents an apolipoprotein E-independent pathway of Abeta uptake and degradation by astrocytes. J Biol Chem. 2012;287:13959-71.
-
(2012)
J Biol Chem
, vol.287
, pp. 13959-13971
-
-
Basak, J.M.1
Verghese, P.B.2
Yoon, H.3
Kim, J.4
Holtzman, D.M.5
-
51
-
-
0032988384
-
Activation of the kallikrein-kinin system in hemodialysis: Role of membrane electronegativity, blood dilution, and pH
-
1:CAS:528:DyaK1MXhvVSnurw%3D 10027949
-
Renaux JL, Thomas M, Crost T, Loughraieb N, Vantard G. Activation of the kallikrein-kinin system in hemodialysis: role of membrane electronegativity, blood dilution, and pH. Kidney Int. 1999;55:1097-103.
-
(1999)
Kidney Int
, vol.55
, pp. 1097-1103
-
-
Renaux, J.L.1
Thomas, M.2
Crost, T.3
Loughraieb, N.4
Vantard, G.5
-
52
-
-
84903714886
-
Resistance of naturally secreted alpha-synuclein to proteolysis
-
1:CAS:528:DC%2BC2cXhtFaltbrN 24723692
-
Ximerakis M, Pampalakis G, Roumeliotis TI, Sykioti VS, Garbis SD, Stefanis L, et al. Resistance of naturally secreted alpha-synuclein to proteolysis. FASEB J. 2014;28:3146-58.
-
(2014)
FASEB J
, vol.28
, pp. 3146-3158
-
-
Ximerakis, M.1
Pampalakis, G.2
Roumeliotis, T.I.3
Sykioti, V.S.4
Garbis, S.D.5
Stefanis, L.6
Sotiropoulou, G.7
Vekrellis, K.8
-
53
-
-
34250666701
-
Production and purification of lentiviral vectors
-
1:CAS:528:DC%2BD28XhtFOitbvP 17406239
-
Tiscornia G, Singer O, Verma IM. Production and purification of lentiviral vectors. Nat Protoc. 2006;1:241-5.
-
(2006)
Nat Protoc
, vol.1
, pp. 241-245
-
-
Tiscornia, G.1
Singer, O.2
Verma, I.M.3
-
54
-
-
70350550208
-
Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases
-
2812014 1:CAS:528:DC%2BD1MXhsVSmtrbF 19864570
-
Spencer B, Potkar R, Trejo M, Rockenstein E, Patrick C, Gindi R, et al. Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases. J Neurosci. 2009;29:13578-88.
-
(2009)
J Neurosci
, vol.29
, pp. 13578-13588
-
-
Spencer, B.1
Potkar, R.2
Trejo, M.3
Rockenstein, E.4
Patrick, C.5
Gindi, R.6
Adame, A.7
Wyss-Coray, T.8
Masliah, E.9
-
55
-
-
0034989411
-
Transduction of liver cells by lentiviral vectors: Analysis in living animals by fluorescence imaging
-
1:CAS:528:DC%2BD38XitVGrs70%3D 11273773
-
Pfeifer A, Kessler T, Yang M, Baranov E, Kootstra N, Cheresh DA, et al. Transduction of liver cells by lentiviral vectors: analysis in living animals by fluorescence imaging. Mol Ther. 2001;3:319-22.
-
(2001)
Mol Ther
, vol.3
, pp. 319-322
-
-
Pfeifer, A.1
Kessler, T.2
Yang, M.3
Baranov, E.4
Kootstra, N.5
Cheresh, D.A.6
Hoffman, R.M.7
Verma, I.M.8
-
56
-
-
84864987239
-
Alzheimer's beta-secretase (BACE1) regulates the cAMP/PKA/CREB pathway independently of beta-amyloid
-
3446780 1:CAS:528:DC%2BC38Xht1Ors73P 22895721
-
Chen Y, Huang X, Zhang YW, Rockenstein E, Bu G, Golde TE, et al. Alzheimer's beta-secretase (BACE1) regulates the cAMP/PKA/CREB pathway independently of beta-amyloid. J Neurosci. 2012;32:11390-5.
-
(2012)
J Neurosci
, vol.32
, pp. 11390-11395
-
-
Chen, Y.1
Huang, X.2
Zhang, Y.W.3
Rockenstein, E.4
Bu, G.5
Golde, T.E.6
Masliah, E.7
Xu, H.8
-
57
-
-
33645109019
-
Selective deficits in the expression of striatal-enriched mRNAs in Huntington's disease
-
1:CAS:528:DC%2BD28XjsFCnurc%3D 16405510
-
Desplats PA, Kass KE, Gilmartin T, Stanwood GD, Woodward EL, Head SR, et al. Selective deficits in the expression of striatal-enriched mRNAs in Huntington's disease. J Neurochem. 2006;96:743-57.
-
(2006)
J Neurochem
, vol.96
, pp. 743-757
-
-
Desplats, P.A.1
Kass, K.E.2
Gilmartin, T.3
Stanwood, G.D.4
Woodward, E.L.5
Head, S.R.6
Sutcliffe, J.G.7
Thomas, E.A.8
-
58
-
-
77949504405
-
Selective molecular alterations in the autophagy pathway in patients with Lewy body disease and in models of alpha-synucleinopathy
-
2824828 20174468
-
Crews L, Spencer B, Desplats P, Patrick C, Paulino A, Rockenstein E, et al. Selective molecular alterations in the autophagy pathway in patients with Lewy body disease and in models of alpha-synucleinopathy. PLoS One. 2010;5:e9313.
-
(2010)
PLoS One
, vol.5
, pp. e9313
-
-
Crews, L.1
Spencer, B.2
Desplats, P.3
Patrick, C.4
Paulino, A.5
Rockenstein, E.6
Hansen, L.7
Adame, A.8
Galasko, D.9
Masliah, E.10
-
59
-
-
84858157780
-
Fluoxetine ameliorates behavioral and neuropathological deficits in a transgenic model mouse of alpha-synucleinopathy
-
3897235 1:CAS:528:DC%2BC38Xjs1GmtLw%3D 22281106
-
Ubhi K, Inglis C, Mante M, Patrick C, Adame A, Spencer B, et al. Fluoxetine ameliorates behavioral and neuropathological deficits in a transgenic model mouse of alpha-synucleinopathy. Exp Neurol. 2012;234:405-16.
-
(2012)
Exp Neurol
, vol.234
, pp. 405-416
-
-
Ubhi, K.1
Inglis, C.2
Mante, M.3
Patrick, C.4
Adame, A.5
Spencer, B.6
Rockenstein, E.7
May, V.8
Winkler, J.9
Masliah, E.10
-
60
-
-
0034681471
-
Dopaminergic loss and inclusion body formation in alpha-synuclein mice: Implications for neurodegenerative disorders
-
1:CAS:528:DC%2BD3cXhtlOqsL4%3D 10678833
-
Masliah E, Rockenstein E, Veinbergs I, Mallory M, Hashimoto M, Takeda A, et al. Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders. Science. 2000;287:1265-9.
-
(2000)
Science
, vol.287
, pp. 1265-1269
-
-
Masliah, E.1
Rockenstein, E.2
Veinbergs, I.3
Mallory, M.4
Hashimoto, M.5
Takeda, A.6
Sagara, Y.7
Sisk, A.8
Mucke, L.9
|