Effects of caffeic and chlorogenic acids on the rat skeletal system

European Review for Medical and Pharmacological Sciences

Volumn 19, Issue 4, 2015, Pages 682-693

  Folwarczna, J ^a   Pytlik, M ^a   Zych, M ^a   Cegiela, U ^a   Nowinska, B ^a   Kaczmarczyk Sedlak, I ^a   Sliwinski, S ^a   Trzeciak, H ^a   Trzeciak, H I ^a  

^a MEDICAL UNIVERSITY OF SILESIA   (Poland)

Author keywords

Caffeic acid; Chlorogenic acid; Osteoporosis; Rats; Skeletal system

Indexed keywords

AGENTS ACTING ON THE PERIPHERAL NERVOUS AND NEUROMUSCULAR SYSTEMS; ANTIESTROGEN; CAFFEIC ACID; CALCIUM; CHLOROGENIC ACID; CHOLESTEROL; ESTRADIOL; ESTROGEN; OSTEOCALCIN; PHOSPHATE; PHOSPHORUS; CAFFEIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; BONE GROWTH; BONE MASS; BONE MINERALIZATION; BONE STRENGTH; BONE TURNOVER; CALCIUM BLOOD LEVEL; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG EFFECT; DRUG MEGADOSE; ESTRADIOL BLOOD LEVEL; ESTROGEN BLOOD LEVEL; ESTROGEN DEFICIENCY; FEMALE; FEMUR DIAPHYSIS; FEMUR EPIPHYSIS; LOW DRUG DOSE; METAPHYSIS; MORPHOMETRICS; NONHUMAN; OSSIFICATION; OSTEOLYSIS; OSTEOPOROSIS; PERIOSTEUM; PHOSPHATE BLOOD LEVEL; PROTEIN BLOOD LEVEL; RAT; TIBIA; TISSUE LEVEL; TRABECULAR BONE; TREATMENT DURATION; TREATMENT OUTCOME; TREATMENT RESPONSE; UPREGULATION; WEIGHT GAIN; YOUNG MODULUS; ANIMAL; BLOOD; BONE; DOSE RESPONSE; DRUG EFFECTS; FEMUR; HUMAN; OVARIECTOMY; WISTAR RAT;

ANIMALS; BONE AND BONES; CAFFEIC ACIDS; CHLOROGENIC ACID; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTRADIOL; ESTROGENS; FEMALE; FEMUR; HUMANS; OSTEOCALCIN; OVARIECTOMY; RATS; RATS, WISTAR; TIBIA;

EID: 84942316334     PISSN: 11283602     EISSN: 22840729     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. STALIKAS CD. Extraction, separation, and detection methods for phenolic acids and flavonoids. J Sep Sci 2007; 30: 3268-3295.
2. EL-SEEDI HR, EL-SAID AM, KHALIFA SA, GÖ RANSSON U, BOHLIN L, BORG-KARLSON AK, VERPOORTE R. Biosynthesis, natural sources, dietary intake, pharmacokinetic properties, and biological activities of hydroxycinnamic acids. J Agric Food Chem 2012; 60: 10877-10895.
3. SASSA S, KIKUCHI T, SHINODA H, SUZUKI S, KUDO H, SAKAMOTO S. Preventive effect of ferulic acid on bone loss in ovariectomized rats. In Vivo 2003; 17: 277-280. 692 J. Folwarczna, M. Pytlik, M. Zych, U. Cegie?a, B. Nowiń ska, I. Kaczmarczyk-Sedlak, L.͆liwiński, et al.
4. TANG QY, KUKITA T, USHIJIMA Y, KUKITA A, NAGATA K, SANDRA F, WATANABE T, TOH K, OKUMA Y, KAWASAKI S, RASUBALA L, TERAMACHI J, MIYAMOTO I, WU Z, IIJIMA T. Regulation of osteoclastogenesis by Simon extracts composed of caffeic acid and related compounds: successful suppression of bone destruction accompanied with a djuvant-induced arthritis in rats. Histochem Cell Biol 2006; 125: 215-225.
5. LAI YL, YAMAGUCHI M. Phytocomponent p-hydroxycinnamic acid stimulates bone formation and inhibits bone resorption in rat femoral tissues in vitro. Mol Cell Biochem 2006; 292: 45-52.
6. LAI YL, YAMAGUCHI M. Phytocomponent p-hydroxycinnamic acid inhibits osteoclast-like cell formation in mouse bone marrow cultures. Int J Mol Med 2007; 19: 123-128.
7. YAMAGUCHI M, LAI YL, UCHIYAMA S, NAKAGAWA T. Oral administration of phytocomponent p-hydroxycinnamic acid prevents bone loss in ovariectomized rats. Mol Cell Biochem 2008; 311: 31-36.
8. YAMAGUCHI M, LAI YL, UCHIYAMA S, NAKAGAWA T. Phytocomponent p-hydroxycinnamic acid stimulates mineralization in osteoblastic MC3T3-E1 cells. Int J Mol Med 2008; 22: 287-291.
9. FOLWARCZNA J, ZYCH M, BURCZYK J, TRZECIAK H, TRZECIAK HI. Effects of natural phenolic acids on the skeletal system of ovariectomized rats. Planta Med 2009; 75: 1567-1572.
10. ZYCH M, FOLWARCZNA J, PYTLIK M, ͆LIWINSKI L, GODEN MA, BURCZYK J, TRZECIAK HI. Administration of caffeic acid worsened bone mechanical properties in female rats. Planta Med 2010; 76: 407-411.
11. CHEN JR, LAZARENKO OP, WU X, KANG J, BLACKBURN ML, SHANKAR K, BADGER TM, RONIS MJ. Dietary-induced serum phenolic acids promote bone growth via p38 MAPK/?-catenin canonical Wnt signaling. J Bo ne Miner Res 2010; 25: 2399-2411
12. HIGDON JV, FREI B. Coffee and health: a review of recent human research. Crit Rev Food Sci Nutr 2006; 46: 101-123.
13. MONTEIR O M, FARAH A, PERRONE D, TRUGO LC, DONANGELO C. Chlorogenic acid compounds from coffee are differentially absorbed and metabolized in humans. J Nutr 2007; 137: 2196-2201.
14. FUJIOKA K, SHIBAMOTO T. Chlorogenic acid and caffeine contents in various commercial brewed coffees. Food Chem 2008; 106: 217-221.
15. DEL RIO D, STALMACH A, CALANI L, CROZIER A. Bioavailability of coffee chlorogenic acids and green tea flavan-3-ols. Nutrients 2010; 2: 820-833.
16. MULLEN W, NEMZER B, OU B, STALMACH A, HUNTER J, CLIFFORD MN, COMBET E. The antioxidant and chlorogenic acid profiles of whole coffee fruits are influenced by the extraction procedures. J Agric Food Chem 2011; 59: 3754-3762.
17. VINSON JA, BURNHAM BR, NAGENDRAN MV. Randomized, double-blind, placebo-controlled, linear dose, crossover study to evaluate the efficacy and safety of a green coffee bean extract in overweight subjects. Diabetes Metab Syndr Obes 2012; 5: 21-27.
18. GEORGE SE, RAMALAKSHMI K, MOHAN RAO LJ. A perception on health benefits of coffee. Crit Rev Food Sci Nutr 2008; 48: 464-486.
19. WINK CS,ROSSOWSKA MJ,NAKAMOTO T. Effects of caffeine on bone cells and bone development in fastgrowing rats Anat Rec 1996, 246, 30-38.
20. OHTA M, IDE K, CHEUK G, CHEUK SL, YAZDANI M, NAKAMOTO T, THOMAS KA. A caffeine diet can alter t he mechanical properties of the bones of young ovariectomized rats. Ann Nutr Metab 2002; 46:108-113.
21. HUANG TH, YANG RS, HSIEH SS, LIU SH. Effects of caffeine and exercise on the development o f bone: a densitometric and histomorphometric study in young Wistar rats. Bone 2002; 30: 293-299.
22. OLCHOWIK G, CHADAJ-POLBERG E, TOMASZEWSKI M, POLBERG M, TOMASZEWSKA M. The influence of c affeine on the biomechanical properties of bone tissue during pregnancy in a population of rats. Folia Histochem Cytobiol 2011; 49: 504-511.
23. LIU SH, CHEN C, YANG RS, YEN YP, YANG YT, TSAI C. Caffeine enhances osteoclast differentiation from bone marrow hematopoietic cells and reduces bone mineral density in growing rats. J Orthop Res 2011; 29: 954-960.
24. SAKAMOTO W, NISHIHIRA J, F UJIE K, IIZUKA T, HANDA H, OZAKI M, YUKAWA S. Effect of coffee consumption on bone metabolism. Bone 2001; 28: 332-336.
25. FOLWARCZNA J, PYTLIK M, ZYCH M, CEGIEA U, KACZMARCZYK-SEDLAK I, NOWIN SKA B, ͆LIWINSKI L. Favorable effect of moderate dose caffeine on the skeletal system in ovariectomized rats. Mol Nutr Food Res 2013; 57: 1772-1784.
26. TURNER CH, BURR DB. Basic bio mechanical measurements of bone: a tutorial. Bone 1993;14: 595-608.
27. STÜRMER EK, SEIDLOVÁ-WUTTKE D, SEHMISCH S, RACK T, WILLE J, FROSCH KH, WUTTKE W, STÜRMER KM. Standardized b ending and breaking test for the normal and osteoporotic metaphyseal tibias of the rat: effect of estradiol, testosterone, and raloxifene. J Bone Miner Res 2006; 21: 89-96.
28. FOLWARCZNA J, PYTLIK M, S LIWINSKI L, CEGIEA U, NOWIN SKA B, RAJDA M. Effects of propranolol on the development of glucocorticoid-induced osteoporosis in male rats. Pharmacol Rep 2011; 63: 1040-1049.
29. CEGIEA U, FOLWARCZNA J, PYTLIK M, ZGÓ RKA G. Effects of extracts from Trifolium medium L. and Trifolium pratense L. on development of estrogen deficiency-induced osteoporosis in rats. Evid Based Complement Alternat Med 2012; ID 921684, 11 pages.
30. FOLWARCZNA J, ZYCH M, NOWIN SKA B, PYTLIK M. Effects of fenugreek (Trigonella foenum-graecum L.) seed on bone mechanical properties in rats. Eur Rev Med Pharmacol Sci 2014; 18; 1937-1947.
31. FOLWARCZNA J, JANIEC W, BAREJ M, CEGIEA U, PYTLIK M, KACZMARCZYK-SEDLAK I. Effects of nadroparin on bone histomorphometric parameters in rats. Pol J Pharmacol 2004; 56: 337-343.
32. ZYCH M, FOLWARCZNA J, TRZECIAK HI. Natural phenolic acids may increase serum estradiol level in ovariectomized rats. Acta Biochim Pol 2009; 56: 503-507.
33. CLIFFORD MN. Chlorogenic acids and other cinnamates-nature, occurrence and dietary burden. J Sci Food Agric 1999; 79: 362-372.
34. SETCHELL KD, BROWN NM, LYDEKING-OLSEN E. The clinical importance of the metabolite equol-A clue to the effectiveness of soy and its isoflavones. J Nutr 2002; 132: 3577-3584.
35. MANOLAGAS SC. From estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosis. Endocr Rev 2010; 31: 266-300
36. FOLWARCZNA J, ͆ LIWINSKI L, CEGIEA U, PYTLIK M, KACZMARCZYK-SEDLAK I, NOWIN SKA B, JANIEC W, TRZECIAK HI. Raloxifene similarly affects the skeletal system of male and ovariectomized female rats. Pharmacol Rep 2007; 59: 349-358.
37. WILLIAMSON G, DIONISI F, RENOUF M. Flavanol s from green tea and phenolic acids from coffee: critical quantitative evaluation of the pharmacokinetic data in humans after consumption of single doses of beverages. Mol Nutr Food Res 2011; 55: 864-873.
38. DU PAS C, MARSSET BAGLIERI A, ORDONAUD C, TOMÉ D, MAILLARD MN. Chlorogenic acid is poorly absorbed, independently of the food matrix: A Caco-2 cells and rat chronic absorption study. Mol Nutr Food Res 2006; 50: 1053-1 060.
39. SATO Y, ITAGAKI S, KUROKAWA T, OGURA J, KOBAYASHI M, HIRANO T, SUGAWARA M, ISEKI K. In vitro and in vivo antioxidant properties of chlorogenic acid and caffeic acid. Int J Pharm 2011; 40 3: 136-138.
40. TSUDA S, EGAWA T, MA X, OSHIMA R, KUROGI E, HAYASHI T. Coffee polyphenol caffeic acid but not chlorogenic acid increases 5'AMP-Activated protein kinase and insulin-independent glucose t ransport in rat skeletal muscle. J Nutr Biochem 2012; 23: 1403-1409.
41. D'ARCHIVIO M,FILESI C,VARÍ R,SCAZZOCCHIO B,MASELLA R. Bioavailability of the polyphenols: status and controversies Int J Mol Sci 2010, 11, 1321-1342.
42. PETERSON CA, KUBAS KL, HARTMAN SJ, ROTTINGHAUS GE, TAYLOR JA, WELSHONS WV. Lack of skeletal e ffect of soy isoflavones in intact growing, female rats may be explained by constant serum estrogenic activity despite reduced serum estradiol. Ann Nutr Metab 2008; 52: 48-57.
43. LECLERCQ G, DE CREMOUX P, THIS P, JACQUOT Y. Lack of sufficient information on the specificity and selectivity of commercial phytoestrogens preparations for therapeutic purposes. Maturitas 2011; 68: 56-64.
44. JEFFERSON WN. Adult ovarian function can be affected by high levels of soy. J Nutr 2010; 140: 2322S-2325S.
45. MARTIN KR, APPEL CL. Polyphenols as dietary supplements: A double-edged sword. Nutr Diet Suppl 2010; 2: 1-12.