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Volumn 27, Issue 10, 2015, Pages 1432-1445

The GPR55 antagonist CID16020046 protects against intestinal inflammation

Author keywords

DSS; GPR55; Intestinal inflammation; TNBS

Indexed keywords

CD11B ANTIGEN; CID 16020046; CYCLOOXYGENASE 2; DOCUSATE SODIUM; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 55; INTERLEUKIN 1BETA; INTERLEUKIN 6; MYELOPEROXIDASE; RECEPTOR BLOCKING AGENT; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 4-(4-(3-HYDROXYPHENYL)-3-(4-METHYLPHENYL)-6-OXO-1H,4H,5H,6H-PYRROLO(3,4-C)PYRAZOL-5-YL)BENZOIC ACID; AZABICYCLO DERIVATIVE; BENZOIC ACID DERIVATIVE; CANNABINOID RECEPTOR; CANNABINOID RECEPTOR ANTAGONIST; DEXTRAN SULFATE; GPR55 PROTEIN, HUMAN; GPR55 PROTEIN, MOUSE; TRINITROBENZENESULFONIC ACID;

EID: 84942296107     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/nmo.12639     Document Type: Article
Times cited : (77)

References (57)
  • 2
    • 58149138962 scopus 로고    scopus 로고
    • 2-Arachidonoyl-sn-glycero-3-phosphoinositol: a possible natural ligand for GPR55
    • Oka S, Toshida T, Maruyama K, Nakajima K, Yamashita A, Suigiura T. 2-Arachidonoyl-sn-glycero-3-phosphoinositol: a possible natural ligand for GPR55. J Biochem 2009; 145: 13-20.
    • (2009) J Biochem , vol.145 , pp. 13-20
    • Oka, S.1    Toshida, T.2    Maruyama, K.3    Nakajima, K.4    Yamashita, A.5    Suigiura, T.6
  • 3
    • 61349143694 scopus 로고    scopus 로고
    • The enigmatic pharmacology of GPR55
    • Ross RA. The enigmatic pharmacology of GPR55. Trends Pharmacol Sci 2009; 30: 156-63.
    • (2009) Trends Pharmacol Sci , vol.30 , pp. 156-163
    • Ross, R.A.1
  • 4
    • 84875841356 scopus 로고    scopus 로고
    • The endocannabinoids anandamide and virodhamine modulate the activity of the candidate cannabinoid receptor GPR55
    • Sharir H, Console-Bram L, Mundy C, Popoff SN, Kapur A, Abood ME. The endocannabinoids anandamide and virodhamine modulate the activity of the candidate cannabinoid receptor GPR55. J Neuroimmune Pharmacol 2012; 7: 856-65.
    • (2012) J Neuroimmune Pharmacol , vol.7 , pp. 856-865
    • Sharir, H.1    Console-Bram, L.2    Mundy, C.3    Popoff, S.N.4    Kapur, A.5    Abood, M.E.6
  • 6
    • 79960275004 scopus 로고    scopus 로고
    • The atypical cannabinoid O-1602 protects against experimental colitis and inhibits neutrophil recruitment
    • Schicho R, Bashashati M, Bawa M, McHugh D, Saur D, Hu HM, Zimmer A, Lutz B et al. The atypical cannabinoid O-1602 protects against experimental colitis and inhibits neutrophil recruitment. Inflamm Bowel Dis 2011; 17: 1651-64.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 1651-1664
    • Schicho, R.1    Bashashati, M.2    Bawa, M.3    McHugh, D.4    Saur, D.5    Hu, H.M.6    Zimmer, A.7    Lutz, B.8
  • 9
    • 84929338552 scopus 로고    scopus 로고
    • The differential characterization of GPR55 receptor in human peripheral blood reveals a distinctive expression in monocytes and NK cells and a proinflammatory role in these innate cells
    • Chiurchiù V, Lanuti M, De Bardi M, Battistini L, Maccarrone M. The differential characterization of GPR55 receptor in human peripheral blood reveals a distinctive expression in monocytes and NK cells and a proinflammatory role in these innate cells. Int Immunol 2015; 27: 153-60.
    • (2015) Int Immunol , vol.27 , pp. 153-160
    • Chiurchiù, V.1    Lanuti, M.2    De Bardi, M.3    Battistini, L.4    Maccarrone, M.5
  • 13
    • 84879314553 scopus 로고    scopus 로고
    • A selective antagonist reveals a potential role of G protein-coupled receptor 55 in platelet and endothelial cell function
    • Kargl J, Brown AJ, Andersen L, Dorn G, Schicho R, Waldhoer M, Heinemann A. A selective antagonist reveals a potential role of G protein-coupled receptor 55 in platelet and endothelial cell function. J Pharmacol Exp Ther 2013; 346: 54-66.
    • (2013) J Pharmacol Exp Ther , vol.346 , pp. 54-66
    • Kargl, J.1    Brown, A.J.2    Andersen, L.3    Dorn, G.4    Schicho, R.5    Waldhoer, M.6    Heinemann, A.7
  • 15
    • 84871793022 scopus 로고    scopus 로고
    • The cannabinoid receptor CB1 modulates the signaling properties of the lysophosphatidylinositol receptor GPR55
    • Kargl J, Balenga N, Parzmair GP, Brown AJ, Heinemann A, Waldhoer M. The cannabinoid receptor CB1 modulates the signaling properties of the lysophosphatidylinositol receptor GPR55. J Biol Chem 2012; 287: 44234-48.
    • (2012) J Biol Chem , vol.287 , pp. 44234-44248
    • Kargl, J.1    Balenga, N.2    Parzmair, G.P.3    Brown, A.J.4    Heinemann, A.5    Waldhoer, M.6
  • 17
    • 77649275461 scopus 로고    scopus 로고
    • Cannabinoids and the gut: new developments and emerging concepts
    • Izzo AA, Sharkey KA. Cannabinoids and the gut: new developments and emerging concepts. Pharmacol Ther 2010; 126: 21-38.
    • (2010) Pharmacol Ther , vol.126 , pp. 21-38
    • Izzo, A.A.1    Sharkey, K.A.2
  • 18
    • 84863112729 scopus 로고    scopus 로고
    • Evidence for the putative cannabinoid receptor (GPR55)-mediated inhibitory effects on intestinal contractility in mice
    • Ross GR, Lichtman A, Dewey WL, Akbarali HI. Evidence for the putative cannabinoid receptor (GPR55)-mediated inhibitory effects on intestinal contractility in mice. Pharmacology 2012; 90: 55-65.
    • (2012) Pharmacology , vol.90 , pp. 55-65
    • Ross, G.R.1    Lichtman, A.2    Dewey, W.L.3    Akbarali, H.I.4
  • 19
    • 84870563609 scopus 로고    scopus 로고
    • A potential role for GPR55 in gastrointestinal functions
    • Schicho R, Storr M. A potential role for GPR55 in gastrointestinal functions. Curr Opin Pharmacol 2012; 12: 653-8.
    • (2012) Curr Opin Pharmacol , vol.12 , pp. 653-658
    • Schicho, R.1    Storr, M.2
  • 20
    • 51549099779 scopus 로고    scopus 로고
    • The putative cannabinoid receptor GPR55 plays a role in mechanical hyperalgesia associated with inflammatory and neuropathic pain
    • Staton PC, Hatcher JP, Walker DJ, Morrison AD, Shapland EM, Hughes JP, Chong E, Mander PK et al. The putative cannabinoid receptor GPR55 plays a role in mechanical hyperalgesia associated with inflammatory and neuropathic pain. Pain 2008; 139: 225-36.
    • (2008) Pain , vol.139 , pp. 225-236
    • Staton, P.C.1    Hatcher, J.P.2    Walker, D.J.3    Morrison, A.D.4    Shapland, E.M.5    Hughes, J.P.6    Chong, E.7    Mander, P.K.8
  • 25
    • 11144255122 scopus 로고    scopus 로고
    • Vanilloid receptor 1 antagonists attenuate disease severity in dextran sulphate sodium-induced colitis in mice
    • Kimball ES, Wallace NH, Schneider CR, D'Andrea MR, Hornby PJ. Vanilloid receptor 1 antagonists attenuate disease severity in dextran sulphate sodium-induced colitis in mice. Neurogastroenterol Motil 2004; 16: 811-8.
    • (2004) Neurogastroenterol Motil , vol.16 , pp. 811-818
    • Kimball, E.S.1    Wallace, N.H.2    Schneider, C.R.3    D'Andrea, M.R.4    Hornby, P.J.5
  • 26
    • 84857931127 scopus 로고    scopus 로고
    • Topical and systemic cannabidiol improves trinitrobenzene sulfonic acid colitis in mice
    • Schicho R, Storr M. Topical and systemic cannabidiol improves trinitrobenzene sulfonic acid colitis in mice. Pharmacology 2012; 89: 149-55.
    • (2012) Pharmacology , vol.89 , pp. 149-155
    • Schicho, R.1    Storr, M.2
  • 28
    • 0019487913 scopus 로고
    • Chemotaxis by mouse macrophage cell lines
    • Aksamit RR, Falk W, Leonard EJ. Chemotaxis by mouse macrophage cell lines. J Immunol 1981; 126: 2194-9.
    • (1981) J Immunol , vol.126 , pp. 2194-2199
    • Aksamit, R.R.1    Falk, W.2    Leonard, E.J.3
  • 29
    • 0028032655 scopus 로고
    • Regulation of monocyte integrin expression by beta-family chemokines
    • Vaddi K, Newton RC. Regulation of monocyte integrin expression by beta-family chemokines. J Immunol 1994; 153: 4721-32.
    • (1994) J Immunol , vol.153 , pp. 4721-4732
    • Vaddi, K.1    Newton, R.C.2
  • 31
    • 84918534060 scopus 로고    scopus 로고
    • Synergistic effects of NOD1 or NOD2 and TLR4 activation on mouse sickness behavior in relation to immune and brain activity markers
    • Farzi A, Reichmann F, Meinitzer A, Mayerhofer R, Jain P, Hassan AM, Fröhlich EE, Wagner K et al. Synergistic effects of NOD1 or NOD2 and TLR4 activation on mouse sickness behavior in relation to immune and brain activity markers. Brain Behav Immun 2015; 44: 106-20.
    • (2015) Brain Behav Immun , vol.44 , pp. 106-120
    • Farzi, A.1    Reichmann, F.2    Meinitzer, A.3    Mayerhofer, R.4    Jain, P.5    Hassan, A.M.6    Fröhlich, E.E.7    Wagner, K.8
  • 33
    • 84875664752 scopus 로고    scopus 로고
    • GPR55, a G-protein coupled receptor for lysophosphatidylinositol, plays a role in motor coordination
    • Wu CS, Chen H, Sun H, Zhu J, Jew CP, Wager-Miller J, Straiker A, Spencer C et al. GPR55, a G-protein coupled receptor for lysophosphatidylinositol, plays a role in motor coordination. PLoS ONE 2013; 8: e60314.
    • (2013) PLoS ONE , vol.8 , pp. e60314
    • Wu, C.S.1    Chen, H.2    Sun, H.3    Zhu, J.4    Jew, C.P.5    Wager-Miller, J.6    Straiker, A.7    Spencer, C.8
  • 37
    • 48149107173 scopus 로고    scopus 로고
    • Targeting endocannabinoid degradation protects against experimental colitis in mice: involvement of CB1 and CB2 receptors
    • Storr MA, Keenan CM, Emmerdinger D, Zhang H, Yüce B, Sibaev A, Massa F, Buckley NE et al. Targeting endocannabinoid degradation protects against experimental colitis in mice: involvement of CB1 and CB2 receptors. J Mol Med (Berl) 2008; 86: 925-36.
    • (2008) J Mol Med (Berl) , vol.86 , pp. 925-936
    • Storr, M.A.1    Keenan, C.M.2    Emmerdinger, D.3    Zhang, H.4    Yüce, B.5    Sibaev, A.6    Massa, F.7    Buckley, N.E.8
  • 40
    • 76849095665 scopus 로고    scopus 로고
    • The role of COX-2 in intestinal inflammation and colorectal cancer
    • Wang D, Dubois RN. The role of COX-2 in intestinal inflammation and colorectal cancer. Oncogene 2010; 29: 781-8.
    • (2010) Oncogene , vol.29 , pp. 781-788
    • Wang, D.1    Dubois, R.N.2
  • 41
    • 23844449031 scopus 로고    scopus 로고
    • The COX-2 inhibitor, rofecoxib, ameliorates dextran sulphate sodium induced colitis in mice
    • Martín AR, Villegas I, Alarcón de la Lastra C. The COX-2 inhibitor, rofecoxib, ameliorates dextran sulphate sodium induced colitis in mice. Inflamm Res 2005; 54: 145-51.
    • (2005) Inflamm Res , vol.54 , pp. 145-151
    • Martín, A.R.1    Villegas, I.2    Alarcón de la Lastra, C.3
  • 42
    • 0344826835 scopus 로고    scopus 로고
    • The cyclo-oxygenase-2 inhibitor, rofecoxib, attenuates mucosal damage due to colitis induced by trinitrobenzene sulphonic acid in rats
    • Martín AR, Villegas I, La Casa C, Alarcón de la Lastra C. The cyclo-oxygenase-2 inhibitor, rofecoxib, attenuates mucosal damage due to colitis induced by trinitrobenzene sulphonic acid in rats. Eur J Pharmacol 2003; 481: 281-91.
    • (2003) Eur J Pharmacol , vol.481 , pp. 281-291
    • Martín, A.R.1    Villegas, I.2    La Casa, C.3    Alarcón de la Lastra, C.4
  • 43
    • 0035080599 scopus 로고    scopus 로고
    • Neuronal COX-2 expression in human myenteric plexus in active inflammatory bowel disease
    • Roberts PJ, Morgan K, Miller R, Hunter JO, Middleton SJ. Neuronal COX-2 expression in human myenteric plexus in active inflammatory bowel disease. Gut 2001; 48: 468-72.
    • (2001) Gut , vol.48 , pp. 468-472
    • Roberts, P.J.1    Morgan, K.2    Miller, R.3    Hunter, J.O.4    Middleton, S.J.5
  • 44
    • 4444231728 scopus 로고    scopus 로고
    • Aggravation of inflammatory bowel disease by cyclooxygenase-2 inhibitors in rats
    • Singh VP, Patil CS, Jain NK, Kulkarni SK. Aggravation of inflammatory bowel disease by cyclooxygenase-2 inhibitors in rats. Pharmacology 2004; 72: 77-84.
    • (2004) Pharmacology , vol.72 , pp. 77-84
    • Singh, V.P.1    Patil, C.S.2    Jain, N.K.3    Kulkarni, S.K.4
  • 45
    • 79953065448 scopus 로고    scopus 로고
    • Prostanoid signaling: dual role for prostaglandin E2 in neurotoxicity
    • Milatovic D, Montine TJ, Aschner M. Prostanoid signaling: dual role for prostaglandin E2 in neurotoxicity. Neurotoxicology 2011; 32: 312-9.
    • (2011) Neurotoxicology , vol.32 , pp. 312-319
    • Milatovic, D.1    Montine, T.J.2    Aschner, M.3
  • 47
    • 84906809152 scopus 로고    scopus 로고
    • Anthocyanin-rich fractions from red raspberries attenuate inflammation in both RAW264.7 macrophages and a mouse model of colitis
    • Li L, Wang L, Wu Z, Yao L, Wu Y, Huang L, Liu K, Zhou X et al. Anthocyanin-rich fractions from red raspberries attenuate inflammation in both RAW264.7 macrophages and a mouse model of colitis. Sci Rep 2014; 4: 6234.
    • (2014) Sci Rep , vol.4 , pp. 6234
    • Li, L.1    Wang, L.2    Wu, Z.3    Yao, L.4    Wu, Y.5    Huang, L.6    Liu, K.7    Zhou, X.8
  • 48
    • 2142701533 scopus 로고    scopus 로고
    • Immunopathogenesis of experimental ulcerative colitis is mediated by eosinophil peroxidase
    • Forbes E, Murase T, Yang M, Matthaei KI, Lee JJ, Foster PS, Hogan SP. Immunopathogenesis of experimental ulcerative colitis is mediated by eosinophil peroxidase. J Immunol 2004; 172: 5664-75.
    • (2004) J Immunol , vol.172 , pp. 5664-5675
    • Forbes, E.1    Murase, T.2    Yang, M.3    Matthaei, K.I.4    Lee, J.J.5    Foster, P.S.6    Hogan, S.P.7
  • 49
    • 0033158529 scopus 로고    scopus 로고
    • Changes in colonic mucosal permeability in mouse colitis induced with dextran sulfate sodium
    • Kitajima S, Takuma S, Morimoto M. Changes in colonic mucosal permeability in mouse colitis induced with dextran sulfate sodium. Exp Anim 1999; 48: 137-43.
    • (1999) Exp Anim , vol.48 , pp. 137-143
    • Kitajima, S.1    Takuma, S.2    Morimoto, M.3
  • 50
    • 2142811722 scopus 로고    scopus 로고
    • The inflammatory infiltrate in theacute stage of the dextran sulphate sodium induced colitis: B cell response differs depending on the percentage of DSS used to induce it
    • Stevceva L, Pavli P, Husband AJ, Doe WF. The inflammatory infiltrate in theacute stage of the dextran sulphate sodium induced colitis: B cell response differs depending on the percentage of DSS used to induce it. BMC Clin Pathol 2001; 1: 3.
    • (2001) BMC Clin Pathol , vol.1 , pp. 3
    • Stevceva, L.1    Pavli, P.2    Husband, A.J.3    Doe, W.F.4
  • 51
    • 0011469747 scopus 로고    scopus 로고
    • Induction of TNBS colitis in mice
    • Chapter 15, Unit 1519
    • Scheiffele F, Fuss IJ. Induction of TNBS colitis in mice. Curr Protoc Immunol 2002; Chapter 15: Unit 15.19.
    • (2002) Curr Protoc Immunol
    • Scheiffele, F.1    Fuss, I.J.2
  • 52
    • 77149154668 scopus 로고    scopus 로고
    • STAT3 and its activators in intestinal defense and mucosal homeostasis
    • Hruz P, Dann SM, Eckmann L. STAT3 and its activators in intestinal defense and mucosal homeostasis. Curr Opin Gastroenterol 2010; 26: 109-15.
    • (2010) Curr Opin Gastroenterol , vol.26 , pp. 109-115
    • Hruz, P.1    Dann, S.M.2    Eckmann, L.3
  • 57
    • 0034056441 scopus 로고    scopus 로고
    • Interleukin-12 induced interferon-gamma increases inflammation in acute dextran sulfate sodium induced colitis in mice
    • Hans W, Schölmerich J, Gross V, Falk W. Interleukin-12 induced interferon-gamma increases inflammation in acute dextran sulfate sodium induced colitis in mice. Eur Cytokine Netw 2000; 11: 67-74.
    • (2000) Eur Cytokine Netw , vol.11 , pp. 67-74
    • Hans, W.1    Schölmerich, J.2    Gross, V.3    Falk, W.4


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