The efficacy of trivalent cyclic hexapeptides to induce lipid clustering in PG/PE membranes correlates with their antimicrobial activity

Biochimica et Biophysica Acta - Biomembranes

Volumn 1848, Issue 11, 2015, Pages 2998-3006

  Finger, Sebastian ^a   Kerth, Andreas ^a   Dathe, Margitta ^b   Blume, Alfred ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

Author keywords

Antimicrobial peptides; Differential scanning calorimetry; Isothermal titration calorimetry; Lipid clustering; Lipid peptide interactions; Model membranes

Indexed keywords

AMINO ACID; CYCLIC ARGINYLARGINYLARGINYLTROPTOPHYLTRYPTOPHYLTRYPTOPHAN; CYCLIC ARGINYLARGINYLTRYPTOPHYLPHENYLALANYLTRYPTOPHAN; CYCLIC ARGINYLPHENYLALANYLARGINYLPHENYLALANYLARGINYLPHENYLALANINE; CYCLIC ARGINYLTRYPTOPHYLARGINYLTRYPTOPHYLARGINYLTRYPTOPHAN; CYCLIC LYSYLLYSYLTRYPTOPHYLTRYPTOPHYLLYSYLPHENYLALANINE; CYCLIC LYSYLTRYPTOPHYLLYSYLTRYPTOPHYLLYSYLTRYPTOPHAN; HEXAPEPTIDE; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLGLYCEROL; UNCLASSIFIED DRUG; ANTIMICROBIAL CATIONIC PEPTIDE; CYCLOPEPTIDE; MEMBRANE LIPID; OLIGOPEPTIDE; PROTEIN BINDING;

AMINO ACID SEQUENCE; ANTIMICROBIAL ACTIVITY; ARTICLE; BINDING AFFINITY; CHEMICAL PHENOMENA; DIFFERENTIAL SCANNING CALORIMETRY; DRUG STRUCTURE; HYDROPHOBICITY; ISOTHERMAL TITRATION CALORIMETRY; LIPID ANALYSIS; LIPID CLUSTERING; LIPID MEMBRANE; MEMBRANE BINDING; NONHUMAN; PRIORITY JOURNAL; STATIC ELECTRICITY; CALORIMETRY; CELL MEMBRANE; CHEMISTRY; DRUG EFFECTS; METABOLISM; PROCEDURES; TEMPERATURE; THERMODYNAMICS;

AMINO ACID SEQUENCE; ANTIMICROBIAL CATIONIC PEPTIDES; CALORIMETRY; CALORIMETRY, DIFFERENTIAL SCANNING; CELL MEMBRANE; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MEMBRANE LIPIDS; OLIGOPEPTIDES; PEPTIDES, CYCLIC; PHOSPHATIDYLETHANOLAMINES; PHOSPHATIDYLGLYCEROLS; PROTEIN BINDING; TEMPERATURE; THERMODYNAMICS;

EID: 84942274877     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2015.09.012     Document Type: Article

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