Evidence for a novel mechanism of antimicrobial action of a cyclic R-,W-rich hexapeptide

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Scheinpflug, Kathi ^a   Krylova, Oxana ^a   Nikolenko, Heike ^a   Thurm, Charley ^a   Dathe, Margitta ^a  

^a LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; BUFORIN II; CARDIOLIPIN; CYCLIC HEXAPEPTIDE; CYCLO(ARGINYLARGINYLARGINYLTRYPTOPHYLPHENYLALANYLTRYPTOPHAN); PHOSPHATIDYLETHANOLAMINE; PHOSPHOLIPID; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; ANTIMICROBIAL CATIONIC PEPTIDE; CYCLOPEPTIDE; LIPOSOME;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL MEMBRANE; BINDING AFFINITY; CONTROLLED STUDY; CYTOPLASM; DRUG MECHANISM; DRUG RESEARCH; DRUG STRUCTURE; DRUG TARGETING; FLUORESCENCE MICROSCOPY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRACELLULAR TRANSPORT; ISOTHERMAL TITRATION CALORIMETRY; LIPID COMPOSITION; MEMBRANE PERMEABILITY; NONHUMAN; PROTEIN INTERACTION; PROTEIN LIPID INTERACTION; PROTEIN TRANSPORT; AMINO ACID SEQUENCE; BACILLUS SUBTILIS; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; HUMAN; METABOLISM; MICROBIOLOGY; MOLECULAR GENETICS;

BACTERIA (MICROORGANISMS);

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BACILLUS SUBTILIS; CARDIOLIPINS; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; HUMANS; LIPOSOMES; MOLECULAR SEQUENCE DATA; PEPTIDES, CYCLIC; PHOSPHOLIPIDS;

EID: 84928793722     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0125056     Document Type: Article

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