-
1
-
-
0036481562
-
The vacuolar (H+)-ATPases-nature's most versatile proton pumps
-
Nishi T and Forgac M: The vacuolar (H+)-ATPases-nature's most versatile proton pumps. Nat Rev Mol Cell Biol 3: 94-103, 2002.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 94-103
-
-
Nishi, T.1
Forgac, M.2
-
2
-
-
84896692098
-
Eukaryotic V-ATPase: Novel structural findings and functional insights
-
Marshansky V, Rubinstein JL and Grüber G: Eukaryotic V-ATPase: Novel structural findings and functional insights. Biochimica Biophy Acta 1837: 857-879, 2014.
-
(2014)
Biochimica Biophy Acta
, vol.1837
, pp. 857-879
-
-
Marshansky, V.1
Rubinstein, J.L.2
Grüber, G.3
-
3
-
-
84883442790
-
Regulation of luminal acidification by the V-ATPase
-
Breton S and Brown D: Regulation of luminal acidification by the V-ATPase. Physiology (Bethesda) 28: 318-329, 2013.
-
(2013)
Physiology (Bethesda)
, vol.28
, pp. 318-329
-
-
Breton, S.1
Brown, D.2
-
4
-
-
84879745804
-
Vacuolar-type proton pump ATPases: Acidification and pathological relationships
-
Sun-Wada GH and Wada Y: Vacuolar-type proton pump ATPases: Acidification and pathological relationships. Histol Histopathol 28: 805-815, 2013.
-
(2013)
Histol Histopathol
, vol.28
, pp. 805-815
-
-
Sun-Wada, G.H.1
Wada, Y.2
-
5
-
-
84893354269
-
Dysregulated pH in tumor microenvironment checkmates cancer therapy
-
Barar J and Omidi Y: Dysregulated pH in tumor microenvironment checkmates cancer therapy. BioImpacts 3: 149-162, 2013.
-
(2013)
BioImpacts
, vol.3
, pp. 149-162
-
-
Barar, J.1
Omidi, Y.2
-
6
-
-
79955545983
-
The vacuolar-ATPase modulates matrix metalloproteinase isoforms in human pancreatic cancer
-
Chung C, Mader CC, Schmitz JC, Atladottir J, Fitchev P, Cornwell ML, Koleske AJ, Crawford SE and Gorelick F: The vacuolar-ATPase modulates matrix metalloproteinase isoforms in human pancreatic cancer. Lab Invest 91: 732-743, 2011.
-
(2011)
Lab Invest
, vol.91
, pp. 732-743
-
-
Chung, C.1
Mader, C.C.2
Schmitz, J.C.3
Atladottir, J.4
Fitchev, P.5
Cornwell, M.L.6
Koleske, A.J.7
Crawford, S.E.8
Gorelick, F.9
-
8
-
-
84885523683
-
HRG-1 enhances cancer cell invasive potential and couples glucose metabolism to cytosolic/extracellular pH gradient regulation by the vacuolar-H(+) ATPase
-
Fogarty FM, O'Keeffe J, Zhadanov A, Papkovsky D, Ayllon V and O'Connor R: HRG-1 enhances cancer cell invasive potential and couples glucose metabolism to cytosolic/extracellular pH gradient regulation by the vacuolar-H(+) ATPase. Oncogene 33: 4653-4663, 2014.
-
(2014)
Oncogene
, vol.33
, pp. 4653-4663
-
-
Fogarty, F.M.1
O'Keeffe, J.2
Zhadanov, A.3
Papkovsky, D.4
Ayllon, V.5
O'Connor, R.6
-
9
-
-
0142026431
-
Vacuolar H+-ATPase inhibitor induces apoptosis via lysosomal dysfunction in the human gastric cancer cell line MKN-1
-
Nakashima S, Hiraku Y, Tada-Oikawa S, Hishita T, Gabazza EC, Tamaki S, Imoto I, Adachi Y and Kawanishi S: Vacuolar H+-ATPase inhibitor induces apoptosis via lysosomal dysfunction in the human gastric cancer cell line MKN-1. J Biochem 134: 359-364, 2003.
-
(2003)
J Biochem
, vol.134
, pp. 359-364
-
-
Nakashima, S.1
Hiraku, Y.2
Tada-Oikawa, S.3
Hishita, T.4
Gabazza, E.C.5
Tamaki, S.6
Imoto, I.7
Adachi, Y.8
Kawanishi, S.9
-
10
-
-
69949137273
-
The vacuolar proton pump, V-ATPase, is required for notch signaling and endosomal trafficking in drosophila
-
Yan Y, Denef N and Schüpbach T: The vacuolar proton pump, V-ATPase, is required for notch signaling and endosomal trafficking in drosophila. Dev Cell 17: 387-402, 2009.
-
(2009)
Dev Cell
, vol.17
, pp. 387-402
-
-
Yan, Y.1
Denef, N.2
Schüpbach, T.3
-
11
-
-
47349120492
-
The V-type H+-ATPase in vesicular trafficking: Targeting, regulation and function
-
Marshansky V and Futai M: The V-type H+-ATPase in vesicular trafficking: Targeting, regulation and function. Curr Opin Cell Biol 20: 415-426, 2008.
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 415-426
-
-
Marshansky, V.1
Futai, M.2
-
12
-
-
79960134603
-
Enhanced lysosomal activity is involved in Bax inhibitor-1-induced regulation of the endoplasmic reticulum (ER) stress response and cell death against ER stress: Involvement of vacuolar H+-ATPase (V-ATPase)
-
Lee GH, Kim DS, Kim HT, Lee JW, Chung CH, Ahn T, Lim JM, Kim IK, Chae HJ and Kim HR: Enhanced lysosomal activity is involved in Bax inhibitor-1-induced regulation of the endoplasmic reticulum (ER) stress response and cell death against ER stress: Involvement of vacuolar H+-ATPase (V-ATPase). J Biol Chem 286: 24743-24753, 2011.
-
(2011)
J Biol Chem
, vol.286
, pp. 24743-24753
-
-
Lee, G.H.1
Kim, D.S.2
Kim, H.T.3
Lee, J.W.4
Chung, C.H.5
Ahn, T.6
Lim, J.M.7
Kim, I.K.8
Chae, H.J.9
Kim, H.R.10
-
13
-
-
84877329980
-
V-ATPase is a candidate therapeutic target for Ewing sarcoma
-
Avnet S, Di Pompo G, Lemma S, Salerno M, Perut F, Bonuccelli G, Granchi D, Zini N and Baldini N: V-ATPase is a candidate therapeutic target for Ewing sarcoma. Biochim Biophys Acta 1832: 1105-1116, 2013.
-
(2013)
Biochim Biophys Acta
, vol.1832
, pp. 1105-1116
-
-
Avnet, S.1
Di Pompo, G.2
Lemma, S.3
Salerno, M.4
Perut, F.5
Bonuccelli, G.6
Granchi, D.7
Zini, N.8
Baldini, N.9
-
15
-
-
84898652799
-
Inhibition of the vacuolar ATPase induces Bnip3-dependent death of cancer cells and a reduction in tumor burden and metastasis
-
Graham RM, Thompson JW and Webster KA: Inhibition of the vacuolar ATPase induces Bnip3-dependent death of cancer cells and a reduction in tumor burden and metastasis. Oncotarget 5: 1162-1173, 2014.
-
(2014)
Oncotarget
, vol.5
, pp. 1162-1173
-
-
Graham, R.M.1
Thompson, J.W.2
Webster, K.A.3
-
16
-
-
9744260934
-
Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs
-
Luciani F, Spada M, De Milito A, Molinari A, Rivoltini L, Montinaro A, Marra M, Lugini L, Logozzi M, Lozupone F, et al: Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs. J Nat Cancer Inst 96: 1702-1713, 2004.
-
(2004)
J Nat Cancer Inst
, vol.96
, pp. 1702-1713
-
-
Luciani, F.1
Spada, M.2
De Milito, A.3
Molinari, A.4
Rivoltini, L.5
Montinaro, A.6
Marra, M.7
Lugini, L.8
Logozzi, M.9
Lozupone, F.10
-
17
-
-
52449104060
-
The proton pump inhibitor inhibits cell growth and induces apoptosis in human hepatoblastoma
-
Morimura T, Fujita K, Akita M, Nagashima M and Satomi A: The proton pump inhibitor inhibits cell growth and induces apoptosis in human hepatoblastoma. Pediat Surg Int 24: 1087-1094, 2008.
-
(2008)
Pediat Surg Int
, vol.24
, pp. 1087-1094
-
-
Morimura, T.1
Fujita, K.2
Akita, M.3
Nagashima, M.4
Satomi, A.5
-
18
-
-
84872527492
-
Genome-wide epigenetic regulation of miRNAs in cancer
-
Baer C, Claus R and Plass C: Genome-wide epigenetic regulation of miRNAs in cancer. Cancer Res 73: 473-477, 2013.
-
(2013)
Cancer Res
, vol.73
, pp. 473-477
-
-
Baer, C.1
Claus, R.2
Plass, C.3
-
19
-
-
84872341893
-
MicroRNAs and DNA damage response: Implications for cancer therapy
-
Wang Y and Taniguchi T: MicroRNAs and DNA damage response: Implications for cancer therapy. Cell Cycle 12: 32-42, 2013.
-
(2013)
Cell Cycle
, vol.12
, pp. 32-42
-
-
Wang, Y.1
Taniguchi, T.2
-
20
-
-
84872288221
-
Mode of cell death induction by pharmacological vacuolar H+-ATPase (V-ATPase) inhibition
-
von Schwarzenberg K, Wiedmann RM, Oak P, Schulz S, Zischka H, Wanner G, Efferth T, Trauner D and Vollmar AM: Mode of cell death induction by pharmacological vacuolar H+-ATPase (V-ATPase) inhibition. J Biol Chem 288: 1385-1396, 2013.
-
(2013)
J Biol Chem
, vol.288
, pp. 1385-1396
-
-
von Schwarzenberg, K.1
Wiedmann, R.M.2
Oak, P.3
Schulz, S.4
Zischka, H.5
Wanner, G.6
Efferth, T.7
Trauner, D.8
Vollmar, A.M.9
-
21
-
-
0031595031
-
Bafilomycin A1 induces apoptosis in the human pancreatic cancer cell line Capan-1
-
Ohta T, Arakawa H, Futagami F, Fushida S, Kitagawa H, Kayahara M, Nagakawa T, Miwa K, Kurashima K, Numata M, et al: Bafilomycin A1 induces apoptosis in the human pancreatic cancer cell line Capan-1. J Pathol 185: 324-330, 1998.
-
(1998)
J Pathol
, vol.185
, pp. 324-330
-
-
Ohta, T.1
Arakawa, H.2
Futagami, F.3
Fushida, S.4
Kitagawa, H.5
Kayahara, M.6
Nagakawa, T.7
Miwa, K.8
Kurashima, K.9
Numata, M.10
-
22
-
-
84878845433
-
Vacuolar H+ ATPase expression and activity is required for Rab27B-dependent invasive growth and metastasis of breast cancer
-
Hendrix A, Sormunen R, Westbroek W, Lambein K, Denys H, Sys G, Braems G, Van den Broecke R, Cocquyt V, Gespach C, et al: Vacuolar H+ ATPase expression and activity is required for Rab27B-dependent invasive growth and metastasis of breast cancer. Int J Cancer 133: 843-854, 2013.
-
(2013)
Int J Cancer
, vol.133
, pp. 843-854
-
-
Hendrix, A.1
Sormunen, R.2
Westbroek, W.3
Lambein, K.4
Denys, H.5
Sys, G.6
Braems, G.7
Van den Broecke, R.8
Cocquyt, V.9
Gespach, C.10
-
23
-
-
84883075411
-
The expression of V-ATPase is associated with drug resistance and pathology of non-small-cell lung cancer
-
Lu Q, Lu S, Huang L, Wang T, Wan Y, Zhou CX, Zhang C, Zhang Z and Li X: The expression of V-ATPase is associated with drug resistance and pathology of non-small-cell lung cancer. Diagn Pathol 8: 145, 2013.
-
(2013)
Diagn Pathol
, vol.8
, pp. 145
-
-
Lu, Q.1
Lu, S.2
Huang, L.3
Wang, T.4
Wan, Y.5
Zhou, C.X.6
Zhang, C.7
Zhang, Z.8
Li, X.9
-
24
-
-
77955405903
-
Cytosolic pH is a second messenger for glucose and regulates the PKA pathway through V-ATPase
-
Dechant R, Binda M, Lee SS, Pelet S, Winderickx J and Peter M: Cytosolic pH is a second messenger for glucose and regulates the PKA pathway through V-ATPase. EMBO J 29: 2515-2526, 2010.
-
(2010)
EMBO J
, vol.29
, pp. 2515-2526
-
-
Dechant, R.1
Binda, M.2
Lee, S.S.3
Pelet, S.4
Winderickx, J.5
Peter, M.6
-
25
-
-
84896903811
-
Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling
-
Valapala M, Wilson C, Hose S, Bhutto IA, Grebe R, Dong A, Greenbaum S, Gu L, Sengupta S, Cano M, et al: Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling. Autophagy 10: 480-496, 2014.
-
(2014)
Autophagy
, vol.10
, pp. 480-496
-
-
Valapala, M.1
Wilson, C.2
Hose, S.3
Bhutto, I.A.4
Grebe, R.5
Dong, A.6
Greenbaum, S.7
Gu, L.8
Sengupta, S.9
Cano, M.10
-
26
-
-
84907519033
-
The lysosomal v-ATPase-ragulator complex is a common activator for AMPK and mTORC1, acting as a switch between catabolism and anabolism
-
Zhang CS, Jiang B, Li M, Zhu M, Peng Y, Zhang YL, Wu YQ, Li TY, Liang Y, Lu Z, et al: The lysosomal v-ATPase-ragulator complex is a common activator for AMPK and mTORC1, acting as a switch between catabolism and anabolism. Cell Metab 20: 526-540, 2014.
-
(2014)
Cell Metab
, vol.20
, pp. 526-540
-
-
Zhang, C.S.1
Jiang, B.2
Li, M.3
Zhu, M.4
Peng, Y.5
Zhang, Y.L.6
Wu, Y.Q.7
Li, T.Y.8
Liang, Y.9
Lu, Z.10
-
27
-
-
84860531411
-
V-ATPase promotes transforming growth factor-β-induced epithelial-mesenchymal transition of rat proximal tubular epithelial cells
-
Cao X, Yang Q, Qin J, Zhao S, Li X, Fan J, Chen W, Zhou Y, Mao H and Yu X: V-ATPase promotes transforming growth factor-β-induced epithelial-mesenchymal transition of rat proximal tubular epithelial cells. Am J Physiol Renal Physiol 302: F1121-F1132, 2012.
-
(2012)
Am J Physiol Renal Physiol
, vol.302
, pp. F1121-F1132
-
-
Cao, X.1
Yang, Q.2
Qin, J.3
Zhao, S.4
Li, X.5
Fan, J.6
Chen, W.7
Zhou, Y.8
Mao, H.9
Yu, X.10
-
28
-
-
84876803808
-
Interleukin-27 inhibits phagosomal acidification by blocking vacuolar ATPases
-
Jung JY and Robinson CM: Interleukin-27 inhibits phagosomal acidification by blocking vacuolar ATPases. Cytokine 62: 202-205, 2013.
-
(2013)
Cytokine
, vol.62
, pp. 202-205
-
-
Jung, J.Y.1
Robinson, C.M.2
|