메뉴 건너뛰기




Volumn 12, Issue 1, 2013, Pages 32-42

MicroRNAs and DNA damage response: Implications for cancer therapy

Author keywords

Chemotherapy; DNA damage response; DNA damaging agents; DNA repair; microRNA; Radiotherapy

Indexed keywords

ANTINEOPLASTIC AGENT; CARBOPLATIN; CISPLATIN; FLUOROURACIL; MICRORNA; MICRORNA 100; MICRORNA 101; MICRORNA 125A; MICRORNA 127; MICRORNA 138; MICRORNA 17 5P; MICRORNA 182; MICRORNA 183; MICRORNA 189; MICRORNA 24; MICRORNA 421; MICRORNA 521; MICRORNA 96; MICRORNA LET7G; NEOCARZINOSTAIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; OLAPARIB; OLIGONUCLEOTIDE; UNCLASSIFIED DRUG;

EID: 84872341893     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.23051     Document Type: Review
Times cited : (90)

References (150)
  • 1
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • PMID:14744438
    • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116:281-97; PMID:14744438; http://dx.doi.org/10.1016/S0092-8674(04)00045- 5.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 2
    • 60149088848 scopus 로고    scopus 로고
    • Origins and Mechanisms of miRNAs and siRNAs
    • PMID:19239886
    • Carthew RW, Sontheimer EJ. Origins and Mechanisms of miRNAs and siRNAs. Cell 2009; 136:642-55; PMID:19239886; http://dx.doi.org/10.1016/j.cell.2009.01. 035.
    • (2009) Cell , vol.136 , pp. 642-655
    • Carthew, R.W.1    Sontheimer, E.J.2
  • 3
    • 67651149479 scopus 로고    scopus 로고
    • MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response
    • PMID:19536137
    • Pothof J, Verkaik NS, van IJcken W, Wiemer EA, Ta VT, van der Horst GT, et al. MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response. EMBO J 2009; 28:2090-9; PMID:19536137; http://dx.doi.org/10.1038/ emboj.2009.156.
    • (2009) EMBO J , vol.28 , pp. 2090-2099
    • Pothof, J.1    Verkaik, N.S.2    Van IJcken, W.3    Wiemer, E.A.4    Ta, V.T.5    Van Der Horst, G.T.6
  • 4
    • 84862777814 scopus 로고    scopus 로고
    • A role for small RNAs in DNA double-strand break repair
    • PMID:22445173
    • Wei W, Ba Z, Gao M, Wu Y, Ma Y, Amiard S, et al. A role for small RNAs in DNA double-strand break repair. Cell 2012; 149:101-12; PMID:22445173; http://dx.doi.org/10.1016/j.cell.2012.03.002.
    • (2012) Cell , vol.149 , pp. 101-112
    • Wei, W.1    Ba, Z.2    Gao, M.3    Wu, Y.4    Ma, Y.5    Amiard, S.6
  • 5
    • 84865135512 scopus 로고    scopus 로고
    • MiR-96 downregulates REV1 and RAD51 to promote cellular sensitivity to cisplatin and PARP inhibition
    • PMID:22761336
    • Wang Y, Huang JW, Calses P, Kemp CJ, Taniguchi T. MiR-96 downregulates REV1 and RAD51 to promote cellular sensitivity to cisplatin and PARP inhibition. Cancer Res 2012; 72:4037-46; PMID:22761336; http://dx.doi.org/10.1158/0008- 5472.CAN-12-0103.
    • (2012) Cancer Res , vol.72 , pp. 4037-4046
    • Wang, Y.1    Huang, J.W.2    Calses, P.3    Kemp, C.J.4    Taniguchi, T.5
  • 6
    • 80051975920 scopus 로고    scopus 로고
    • MicroRNA-138 modulates DNA damage response by repressing histone H2AX expression
    • PMID:21693595
    • Wang Y, Huang JW, Li M, Cavenee WK, Mitchell PS, Zhou X, et al. MicroRNA-138 modulates DNA damage response by repressing histone H2AX expression. Mol Cancer Res 2011; 9:1100-11; PMID:21693595; http://dx.doi.org/10. 1158/1541-7786.MCR-11-0007.
    • (2011) Mol Cancer Res , vol.9 , pp. 1100-1111
    • Wang, Y.1    Huang, J.W.2    Li, M.3    Cavenee, W.K.4    Mitchell, P.S.5    Zhou, X.6
  • 7
    • 66149157349 scopus 로고    scopus 로고
    • miR-24-mediated downregulation of H2AX suppresses DNA repair in terminally differentiated blood cells
    • PMID:19377482
    • Lal A, Pan Y, Navarro F, Dykxhoorn DM, Moreau L, Meire E, et al. miR-24-mediated downregulation of H2AX suppresses DNA repair in terminally differentiated blood cells. Nat Struct Mol Biol 2009; 16:492-8; PMID:19377482; http://dx.doi.org/10.1038/nsmb.1589.
    • (2009) Nat Struct Mol Biol , vol.16 , pp. 492-498
    • Lal, A.1    Pan, Y.2    Navarro, F.3    Dykxhoorn, D.M.4    Moreau, L.5    Meire, E.6
  • 8
    • 78651468714 scopus 로고    scopus 로고
    • miR-182-mediated downregulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitors
    • PMID:21195000
    • Moskwa P, Buffa FM, Pan Y, Panchakshari R, Gottipati P, Muschel RJ, et al. miR-182-mediated downregulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitors. Mol Cell 2011; 41:210-20; PMID:21195000; http://dx.doi.org/10.1016/j.molcel.2010.12.005.
    • (2011) Mol Cell , vol.41 , pp. 210-220
    • Moskwa, P.1    Buffa, F.M.2    Pan, Y.3    Panchakshari, R.4    Gottipati, P.5    Muschel, R.J.6
  • 9
    • 81155127342 scopus 로고    scopus 로고
    • MicroRNAs in mutagenesis, genomic instability, and DNA repair
    • PMID:22082760
    • Landau DA, Slack FJ. MicroRNAs in mutagenesis, genomic instability, and DNA repair. Semin Oncol 2011; 38:743-51; PMID:22082760; http://dx.doi.org/10. 1053/j.seminoncol.2011.08.003.
    • (2011) Semin Oncol , vol.38 , pp. 743-751
    • Landau, D.A.1    Slack, F.J.2
  • 10
    • 79958207254 scopus 로고    scopus 로고
    • MicroRNAs: New players in the DNA damage response
    • PMID:21183529
    • Hu H, Gatti RA. MicroRNAs: new players in the DNA damage response. J Mol Cell Biol 2011; 3:151-8; PMID:21183529; http://dx.doi.org/10.1093/jmcb/mjq042.
    • (2011) J Mol Cell Biol , vol.3 , pp. 151-158
    • Hu, H.1    Gatti, R.A.2
  • 11
    • 81255176995 scopus 로고    scopus 로고
    • Posttranscriptional regulation of miRNAs in the DNA damage response
    • PMID:21941125
    • Zhang X, Lu X. Posttranscriptional regulation of miRNAs in the DNA damage response. RNA Biol 2011; 8:960-3; PMID:21941125; http://dx.doi.org/10.4161/rna. 8.6.17337.
    • (2011) RNA Biol , vol.8 , pp. 960-963
    • Zhang, X.1    Lu, X.2
  • 12
    • 78649336706 scopus 로고    scopus 로고
    • The DNA damage response: Making it safe to play with knives
    • PMID:20965415
    • Ciccia A, Elledge SJ. The DNA damage response: making it safe to play with knives. Mol Cell 2010; 40:179-204; PMID:20965415; http://dx.doi.org/10. 1016/j.molcel.2010.09.019.
    • (2010) Mol Cell , vol.40 , pp. 179-204
    • Ciccia, A.1    Elledge, S.J.2
  • 13
    • 70350324640 scopus 로고    scopus 로고
    • Emerging common themes in regulation of PIKKs and PI3Ks
    • PMID:19779456
    • Lempiäinen H, Halazonetis TD. Emerging common themes in regulation of PIKKs and PI3Ks. EMBO J 2009; 28:3067-73; PMID:19779456; http://dx.doi.org/ 10.1038/emboj.2009.281.
    • (2009) EMBO J , vol.28 , pp. 3067-3073
    • Lempiäinen, H.1    Halazonetis, T.D.2
  • 14
    • 79957547966 scopus 로고    scopus 로고
    • Beyond ATM: The protein kinase landscape of the DNA damage response
    • PMID:21570395
    • Bensimon A, Aebersold R, Shiloh Y. Beyond ATM: the protein kinase landscape of the DNA damage response. FEBS Lett 2011; 585:1625-39; PMID:21570395; http://dx.doi.org/10.1016/j.febslet.2011.05.013.
    • (2011) FEBS Lett , vol.585 , pp. 1625-1639
    • Bensimon, A.1    Aebersold, R.2    Shiloh, Y.3
  • 15
    • 34247251276 scopus 로고    scopus 로고
    • Single- and double-stranded DNA: Building a trigger of ATR-mediated DNA damage response
    • PMID:17437994
    • Zou L. Single- and double-stranded DNA: building a trigger of ATR-mediated DNA damage response. Genes Dev 2007; 21:879-85; PMID:17437994; http://dx.doi.org/10.1101/gad.1550307.
    • (2007) Genes Dev , vol.21 , pp. 879-885
    • Zou, L.1
  • 16
    • 34247257202 scopus 로고    scopus 로고
    • The structural determinants of checkpoint activation
    • PMID:17437996
    • MacDougall CA, Byun TS, Van C, Yee MC, Cimprich KA. The structural determinants of checkpoint activation. Genes Dev 2007; 21:898-903; PMID:17437996; http://dx.doi.org/10.1101/gad.1522607.
    • (2007) Genes Dev , vol.21 , pp. 898-903
    • MacDougall, C.A.1    Byun, T.S.2    Van, C.3    Yee, M.C.4    Cimprich, K.A.5
  • 17
    • 1642556817 scopus 로고    scopus 로고
    • A double-strand break repair defect in ATM-deficient cells contributes to radiosensitivity
    • PMID:14744762
    • Kühne M, Riballo E, Rief N, Rothkamm K, Jeggo PA, Löbrich M. A double-strand break repair defect in ATM-deficient cells contributes to radiosensitivity. Cancer Res 2004; 64:500-8; PMID:14744762; http://dx.doi.org/ 10.1158/0008-5472.CAN-03-2384.
    • (2004) Cancer Res , vol.64 , pp. 500-508
    • Kühne, M.1    Riballo, E.2    Rief, N.3    Rothkamm, K.4    Jeggo, P.A.5    Löbrich, M.6
  • 18
    • 47749141560 scopus 로고    scopus 로고
    • ATR: An essential regulator of genome integrity
    • PMID:18594563
    • Cimprich KA, Cortez D. ATR: an essential regulator of genome integrity. Nat Rev Mol Cell Biol 2008; 9:616-27; PMID:18594563; http://dx.doi.org/10.1038/ nrm2450.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 616-627
    • Cimprich, K.A.1    Cortez, D.2
  • 19
    • 17244373777 scopus 로고    scopus 로고
    • Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
    • PMID:15829967
    • Farmer H, McCabe N, Lord CJ, Tutt AN, Johnson DA, Richardson TB, et al. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature 2005; 434:917-21; PMID:15829967; http://dx.doi.org/10.1038/nature03445.
    • (2005) Nature , vol.434 , pp. 917-921
    • Farmer, H.1    McCabe, N.2    Lord, C.J.3    Tutt, A.N.4    Johnson, D.A.5    Richardson, T.B.6
  • 20
    • 17244375049 scopus 로고    scopus 로고
    • Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
    • PMID:15829966
    • Bryant HE, Schultz N, Thomas HD, Parker KM, Flower D, Lopez E, et al. Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase. Nature 2005; 434:913-7; PMID:15829966; http://dx.doi.org/10.1038/ nature03443.
    • (2005) Nature , vol.434 , pp. 913-917
    • Bryant, H.E.1    Schultz, N.2    Thomas, H.D.3    Parker, K.M.4    Flower, D.5    Lopez, E.6
  • 21
    • 79952746216 scopus 로고    scopus 로고
    • Secondary mutations of BRCA1/2 and drug resistance
    • PMID:21205087
    • Dhillon KK, Swisher EM, Taniguchi T. Secondary mutations of BRCA1/2 and drug resistance. Cancer Sci 2011; 102:663-9; PMID:21205087; http://dx.doi.org/ 10.1111/j.1349-7006.2010.01840.x.
    • (2011) Cancer Sci , vol.102 , pp. 663-669
    • Dhillon, K.K.1    Swisher, E.M.2    Taniguchi, T.3
  • 22
    • 39749166975 scopus 로고    scopus 로고
    • DNA repair pathways as targets for cancer therapy
    • PMID:18256616
    • Helleday T, Petermann E, Lundin C, Hodgson B, Sharma RA. DNA repair pathways as targets for cancer therapy. Nat Rev Cancer 2008; 8:193-204; PMID:18256616; http://dx.doi.org/10.1038/nrc2342.
    • (2008) Nat Rev Cancer , vol.8 , pp. 193-204
    • Helleday, T.1    Petermann, E.2    Lundin, C.3    Hodgson, B.4    Sharma, R.A.5
  • 23
    • 33845370280 scopus 로고    scopus 로고
    • RNA polymerase III transcribes human microRNAs
    • PMID:17099701
    • Borchert GM, Lanier W, Davidson BL. RNA polymerase III transcribes human microRNAs. Nat Struct Mol Biol 2006; 13:1097-101; PMID:17099701; http://dx.doi.org/10.1038/nsmb1167.
    • (2006) Nat Struct Mol Biol , vol.13 , pp. 1097-1101
    • Borchert, G.M.1    Lanier, W.2    Davidson, B.L.3
  • 24
    • 0347988235 scopus 로고    scopus 로고
    • Nuclear export of microRNA precursors
    • PMID:14631048
    • Lund E, Güttinger S, Calado A, Dahlberg JE, Kutay U. Nuclear export of microRNA precursors. Science 2004; 303:95-8; PMID:14631048; http://dx.doi.org/10.1126/science.1090599.
    • (2004) Science , vol.303 , pp. 95-98
    • Lund, E.1    Güttinger, S.2    Calado, A.3    Dahlberg, J.E.4    Kutay, U.5
  • 25
    • 23644433363 scopus 로고    scopus 로고
    • TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing
    • PMID:15973356
    • Chendrimada TP, Gregory RI, Kumaraswamy E, Norman J, Cooch N, Nishikura K, et al. TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature 2005; 436:740-4; PMID:15973356; http://dx.doi.org/10. 1038/nature03868.
    • (2005) Nature , vol.436 , pp. 740-744
    • Chendrimada, T.P.1    Gregory, R.I.2    Kumaraswamy, E.3    Norman, J.4    Cooch, N.5    Nishikura, K.6
  • 26
    • 27744537851 scopus 로고    scopus 로고
    • Human RISC couples microRNA biogenesis and posttranscriptional gene silencing
    • PMID:16271387
    • Gregory RI, Chendrimada TP, Cooch N, Shiekhattar R. Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell 2005; 123:631-40; PMID:16271387; http://dx.doi.org/10.1016/j.cell.2005.10.022.
    • (2005) Cell , vol.123 , pp. 631-640
    • Gregory, R.I.1    Chendrimada, T.P.2    Cooch, N.3    Shiekhattar, R.4
  • 27
    • 0142165224 scopus 로고    scopus 로고
    • Functional siRNAs and miRNAs exhibit strand bias
    • PMID:14567918
    • Khvorova A, Reynolds A, Jayasena SD. Functional siRNAs and miRNAs exhibit strand bias. Cell 2003; 115:209-16; PMID:14567918; http://dx.doi.org/10.1016/ S0092-8674(03)00801-8.
    • (2003) Cell , vol.115 , pp. 209-216
    • Khvorova, A.1    Reynolds, A.2    Jayasena, S.D.3
  • 28
    • 10744225153 scopus 로고    scopus 로고
    • Asymmetry in the assembly of the RNAi enzyme complex
    • PMID:14567917
    • Schwarz DS, Hutvágner G, Du T, Xu Z, Aronin N, Zamore PD. Asymmetry in the assembly of the RNAi enzyme complex. Cell 2003; 115:199-208; PMID:14567917; http://dx.doi.org/10.1016/S0092-8674(03)00759-1.
    • (2003) Cell , vol.115 , pp. 199-208
    • Schwarz, D.S.1    Hutvágner, G.2    Du, T.3    Xu, Z.4    Aronin, N.5    Zamore, P.D.6
  • 29
    • 34547441263 scopus 로고    scopus 로고
    • Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5′ UTR as in the 3′ UTR
    • PMID:17535905
    • Lytle JR, Yario TA, Steitz JA. Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5′ UTR as in the 3′ UTR. Proc Natl Acad Sci USA 2007; 104:9667-72; PMID:17535905; http://dx.doi.org/10.1073/pnas. 0703820104.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 9667-9672
    • Lytle, J.R.1    Yario, T.A.2    Steitz, J.A.3
  • 30
    • 54549108798 scopus 로고    scopus 로고
    • MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation
    • PMID:18806776
    • Tay Y, Zhang J, Thomson AM, Lim B, Rigoutsos I. MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation. Nature 2008; 455:1124-8; PMID:18806776; http://dx.doi.org/10.1038/nature07299.
    • (2008) Nature , vol.455 , pp. 1124-1128
    • Tay, Y.1    Zhang, J.2    Thomson, A.M.3    Lim, B.4    Rigoutsos, I.5
  • 31
    • 33846277696 scopus 로고    scopus 로고
    • Repression of protein synthesis by miRNAs: How many mechanisms?
    • PMID:17197185
    • Pillai RS, Bhattacharyya SN, Filipowicz W. Repression of protein synthesis by miRNAs: how many mechanisms? Trends Cell Biol 2007; 17:118-26; PMID:17197185; http://dx.doi.org/10.1016/j.tcb.2006.12.007.
    • (2007) Trends Cell Biol , vol.17 , pp. 118-126
    • Pillai, R.S.1    Bhattacharyya, S.N.2    Filipowicz, W.3
  • 32
    • 84863005508 scopus 로고    scopus 로고
    • Autoregulation of microRNA biogenesis by let-7 and Argonaute
    • PMID:22722835
    • Zisoulis DG, Kai ZS, Chang RK, Pasquinelli AE. Autoregulation of microRNA biogenesis by let-7 and Argonaute. Nature 2012; 486:541-4; PMID:22722835.
    • (2012) Nature , vol.486 , pp. 541-544
    • Zisoulis, D.G.1    Kai, Z.S.2    Chang, R.K.3    Pasquinelli, A.E.4
  • 33
    • 54349104464 scopus 로고    scopus 로고
    • Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicerdependent small RNAs
    • PMID:18923076
    • Babiarz JE, Ruby JG, Wang Y, Bartel DP, Blelloch R. Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicerdependent small RNAs. Genes Dev 2008; 22:2773-85; PMID:18923076; http://dx.doi.org/10.1101/gad.1705308.
    • (2008) Genes Dev , vol.22 , pp. 2773-2785
    • Babiarz, J.E.1    Ruby, J.G.2    Wang, Y.3    Bartel, D.P.4    Blelloch, R.5
  • 34
    • 84859963228 scopus 로고    scopus 로고
    • Biogenesis of mammalian microRNAs by a noncanonical processing pathway
    • PMID:22270084
    • Havens MA, Reich AA, Duelli DM, Hastings ML. Biogenesis of mammalian microRNAs by a noncanonical processing pathway. Nucleic Acids Res 2012; 40:4626-40; PMID:22270084; http://dx.doi.org/10.1093/nar/gks026.
    • (2012) Nucleic Acids Res , vol.40 , pp. 4626-4640
    • Havens, M.A.1    Reich, A.A.2    Duelli, D.M.3    Hastings, M.L.4
  • 35
    • 77956995245 scopus 로고    scopus 로고
    • Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis
    • PMID:20699384
    • Yang JS, Maurin T, Robine N, Rasmussen KD, Jeffrey KL, Chandwani R, et al. Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis. Proc Natl Acad Sci USA 2010; 107:15163-8; PMID:20699384; http://dx.doi.org/10.1073/pnas.1006432107.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 15163-15168
    • Yang, J.S.1    Maurin, T.2    Robine, N.3    Rasmussen, K.D.4    Jeffrey, K.L.5    Chandwani, R.6
  • 36
    • 77953183812 scopus 로고    scopus 로고
    • A dicer-independent miRNA biogenesis pathway that requires Ago catalysis
    • PMID:20424607
    • Cheloufi S, Dos Santos CO, Chong MM, Hannon GJ. A dicer-independent miRNA biogenesis pathway that requires Ago catalysis. Nature 2010; 465:584-9; PMID:20424607; http://dx.doi.org/10.1038/nature09092.
    • (2010) Nature , vol.465 , pp. 584-589
    • Cheloufi, S.1    Dos Santos, C.O.2    Chong, M.M.3    Hannon, G.J.4
  • 37
    • 77953897182 scopus 로고    scopus 로고
    • A novel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activity
    • PMID:20448148
    • Cifuentes D, Xue H, Taylor DW, Patnode H, Mishima Y, Cheloufi S, et al. A novel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activity. Science 2010; 328:1694-8; PMID:20448148; http://dx.doi.org/10.1126/science.1190809.
    • (2010) Science , vol.328 , pp. 1694-1698
    • Cifuentes, D.1    Xue, H.2    Taylor, D.W.3    Patnode, H.4    Mishima, Y.5    Cheloufi, S.6
  • 38
    • 34247876168 scopus 로고    scopus 로고
    • DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs
    • PMID:17435748
    • Fukuda T, Yamagata K, Fujiyama S, Matsumoto T, Koshida I, Yoshimura K, et al. DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs. Nat Cell Biol 2007; 9:604-11; PMID:17435748; http://dx.doi.org/10.1038/ncb1577.
    • (2007) Nat Cell Biol , vol.9 , pp. 604-611
    • Fukuda, T.1    Yamagata, K.2    Fujiyama, S.3    Matsumoto, T.4    Koshida, I.5    Yoshimura, K.6
  • 39
    • 46449128469 scopus 로고    scopus 로고
    • SMAD proteins control DROSHA-mediated microRNA maturation
    • PMID:18548003
    • Davis BN, Hilyard AC, Lagna G, Hata A. SMAD proteins control DROSHA-mediated microRNA maturation. Nature 2008; 454:56-61; PMID:18548003; http://dx.doi.org/10.1038/nature07086.
    • (2008) Nature , vol.454 , pp. 56-61
    • Davis, B.N.1    Hilyard, A.C.2    Lagna, G.3    Hata, A.4
  • 40
    • 77955484492 scopus 로고    scopus 로고
    • Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha
    • PMID:20705240
    • Davis BN, Hilyard AC, Nguyen PH, Lagna G, Hata A. Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha. Mol Cell 2010; 39:373-84; PMID:20705240; http://dx.doi.org/10.1016/j.molcel.2010.07.011.
    • (2010) Mol Cell , vol.39 , pp. 373-384
    • Davis, B.N.1    Hilyard, A.C.2    Nguyen, P.H.3    Lagna, G.4    Hata, A.5
  • 41
    • 48249158259 scopus 로고    scopus 로고
    • The FHA domain proteins DAWDLE in Arabidopsis and SNIP1 in humans act in small RNA biogenesis
    • PMID:18632581
    • Yu B, Bi L, Zheng B, Ji L, Chevalier D, Agarwal M, et al. The FHA domain proteins DAWDLE in Arabidopsis and SNIP1 in humans act in small RNA biogenesis. Proc Natl Acad Sci USA 2008; 105:10073-8; PMID:18632581; http://dx.doi.org/10. 1073/pnas.0804218105.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 10073-10078
    • Yu, B.1    Bi, L.2    Zheng, B.3    Ji, L.4    Chevalier, D.5    Agarwal, M.6
  • 42
    • 84857772495 scopus 로고    scopus 로고
    • TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes
    • PMID:22323604
    • Kawahara Y, Mieda-Sato A. TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes. Proc Natl Acad Sci USA 2012; 109:3347-52; PMID:22323604; http://dx.doi.org/10.1073/pnas.1112427109.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 3347-3352
    • Kawahara, Y.1    Mieda-Sato, A.2
  • 43
    • 77950357450 scopus 로고    scopus 로고
    • A splicing-independent function of SF2/ASF in microRNA processing
    • PMID:20385090
    • Wu H, Sun S, Tu K, Gao Y, Xie B, Krainer AR, et al. A splicing-independent function of SF2/ASF in microRNA processing. Mol Cell 2010; 38:67-77; PMID:20385090; http://dx.doi.org/10.1016/j.molcel.2010.02.021.
    • (2010) Mol Cell , vol.38 , pp. 67-77
    • Wu, H.1    Sun, S.2    Tu, K.3    Gao, Y.4    Xie, B.5    Krainer, A.R.6
  • 44
    • 67650080812 scopus 로고    scopus 로고
    • The NF90-NF45 complex functions as a negative regulator in the microRNA processing pathway
    • PMID:19398578
    • Sakamoto S, Aoki K, Higuchi T, Todaka H, Morisawa K, Tamaki N, et al. The NF90-NF45 complex functions as a negative regulator in the microRNA processing pathway. Mol Cell Biol 2009; 29:3754-69; PMID:19398578; http://dx.doi.org/10. 1128/MCB.01836-08.
    • (2009) Mol Cell Biol , vol.29 , pp. 3754-3769
    • Sakamoto, S.1    Aoki, K.2    Higuchi, T.3    Todaka, H.4    Morisawa, K.5    Tamaki, N.6
  • 45
  • 46
    • 70350013561 scopus 로고    scopus 로고
    • Maturation of microRNA is hormonally regulated by a nuclear receptor
    • PMID:19854141
    • Yamagata K, Fujiyama S, Ito S, Ueda T, Murata T, Naitou M, et al. Maturation of microRNA is hormonally regulated by a nuclear receptor. Mol Cell 2009; 36:340-7; PMID:19854141; http://dx.doi.org/10.1016/j.molcel.2009.08.017.
    • (2009) Mol Cell , vol.36 , pp. 340-347
    • Yamagata, K.1    Fujiyama, S.2    Ito, S.3    Ueda, T.4    Murata, T.5    Naitou, M.6
  • 47
    • 80555127350 scopus 로고    scopus 로고
    • MCPIP1 ribonuclease antagonizes dicer and terminates microRNA biogenesis through precursor microRNA degradation
    • PMID:22055188
    • Suzuki HI, Arase M, Matsuyama H, Choi YL, Ueno T, Mano H, et al. MCPIP1 ribonuclease antagonizes dicer and terminates microRNA biogenesis through precursor microRNA degradation. Mol Cell 2011; 44:424-36; PMID:22055188; http://dx.doi.org/10.1016/j.molcel.2011.09.012.
    • (2011) Mol Cell , vol.44 , pp. 424-436
    • Suzuki, H.I.1    Arase, M.2    Matsuyama, H.3    Choi, Y.L.4    Ueno, T.5    Mano, H.6
  • 48
    • 76749126233 scopus 로고    scopus 로고
    • A brief review on the mechanisms of miRNA regulation
    • PMID:20172487
    • Cai Y, Yu X, Hu S, Yu J. A brief review on the mechanisms of miRNA regulation. Genomics Proteomics Bioinformatics 2009; 7:147-54; PMID:20172487; http://dx.doi.org/10.1016/S1672-0229(08)60044-3.
    • (2009) Genomics Proteomics Bioinformatics , vol.7 , pp. 147-154
    • Cai, Y.1    Yu, X.2    Hu, S.3    Yu, J.4
  • 50
    • 3342969381 scopus 로고    scopus 로고
    • RNA editing of a miRNA precursor
    • PMID:15272117
    • Luciano DJ, Mirsky H, Vendetti NJ, Maas S. RNA editing of a miRNA precursor. RNA 2004; 10:1174-7; PMID:15272117; http://dx.doi.org/10.1261/rna. 7350304.
    • (2004) RNA , vol.10 , pp. 1174-1177
    • Luciano, D.J.1    Mirsky, H.2    Vendetti, N.J.3    Maas, S.4
  • 51
    • 30044443191 scopus 로고    scopus 로고
    • Modulation of microRNA processing and expression through RNA editing by ADAR deaminases
    • PMID:16369484
    • Yang W, Chendrimada TP, Wang Q, Higuchi M, Seeburg PH, Shiekhattar R, et al. Modulation of microRNA processing and expression through RNA editing by ADAR deaminases. Nat Struct Mol Biol 2006; 13:13-21; PMID:16369484; http://dx.doi.org/10.1038/nsmb1041.
    • (2006) Nat Struct Mol Biol , vol.13 , pp. 13-21
    • Yang, W.1    Chendrimada, T.P.2    Wang, Q.3    Higuchi, M.4    Seeburg, P.H.5    Shiekhattar, R.6
  • 52
    • 33847317017 scopus 로고    scopus 로고
    • Redirection of silencing targets by adenosine-to-inosine editing of miRNAs
    • PMID:17322061
    • Kawahara Y, Zinshteyn B, Sethupathy P, Iizasa H, Hatzigeorgiou AG, Nishikura K. Redirection of silencing targets by adenosine-to-inosine editing of miRNAs. Science 2007; 315:1137-40; PMID:17322061; http://dx.doi.org/10.1126/ science.1138050.
    • (2007) Science , vol.315 , pp. 1137-1140
    • Kawahara, Y.1    Zinshteyn, B.2    Sethupathy, P.3    Iizasa, H.4    Hatzigeorgiou, A.G.5    Nishikura, K.6
  • 53
    • 80053208703 scopus 로고    scopus 로고
    • Deep sequencing of microRNA precursors reveals extensive 3' end modification
    • PMID:21849429
    • Newman MA, Mani V, Hammond SM. Deep sequencing of microRNA precursors reveals extensive 3' end modification. RNA 2011; 17:1795-803; PMID:21849429; http://dx.doi.org/10.1261/rna.2713611.
    • (2011) RNA , vol.17 , pp. 1795-1803
    • Newman, M.A.1    Mani, V.2    Hammond, S.M.3
  • 54
    • 53949088050 scopus 로고    scopus 로고
    • Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA
    • PMID:18951094
    • Heo I, Joo C, Cho J, Ha M, Han J, Kim VN. Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA. Mol Cell 2008; 32:276-84; PMID:18951094; http://dx.doi.org/10.1016/j.molcel.2008.09.014.
    • (2008) Mol Cell , vol.32 , pp. 276-284
    • Heo, I.1    Joo, C.2    Cho, J.3    Ha, M.4    Han, J.5    Kim, V.N.6
  • 55
    • 68749102148 scopus 로고    scopus 로고
    • TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation
    • PMID:19703396
    • Heo I, Joo C, Kim YK, Ha M, Yoon MJ, Cho J, et al. TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation. Cell 2009; 138:696-708; PMID:19703396; http://dx.doi.org/10.1016/j.cell.2009.08.002.
    • (2009) Cell , vol.138 , pp. 696-708
    • Heo, I.1    Joo, C.2    Kim, Y.K.3    Ha, M.4    Yoon, M.J.5    Cho, J.6
  • 56
    • 70349577785 scopus 로고    scopus 로고
    • Phosphorylation of the human microRNA-generating complex mediates MAPK/Erk signaling
    • PMID:19804757
    • Paroo Z, Ye X, Chen S, Liu Q. Phosphorylation of the human microRNA-generating complex mediates MAPK/Erk signaling. Cell 2009; 139:112-22; PMID:19804757; http://dx.doi.org/10.1016/j.cell.2009.06.044.
    • (2009) Cell , vol.139 , pp. 112-122
    • Paroo, Z.1    Ye, X.2    Chen, S.3    Liu, Q.4
  • 57
    • 78049390388 scopus 로고    scopus 로고
    • Phosphorylation of the RNase III enzyme Drosha at Serine300 or Serine302 is required for its nuclear localization
    • PMID:20554852
    • Tang X, Zhang Y, Tucker L, Ramratnam B. Phosphorylation of the RNase III enzyme Drosha at Serine300 or Serine302 is required for its nuclear localization. Nucleic Acids Res 2010; 38:6610-9; PMID:20554852; http://dx.doi.org/10.1093/nar/gkq547.
    • (2010) Nucleic Acids Res , vol.38 , pp. 6610-6619
    • Tang, X.1    Zhang, Y.2    Tucker, L.3    Ramratnam, B.4
  • 58
    • 70349453924 scopus 로고    scopus 로고
    • Active turnover modulates mature microRNA activity in Caenorhabditis elegans
    • PMID:19734881
    • Chatterjee S, Grosshans H. Active turnover modulates mature microRNA activity in Caenorhabditis elegans. Nature 2009; 461:546-9; PMID:19734881; http://dx.doi.org/10.1038/nature08349.
    • (2009) Nature , vol.461 , pp. 546-549
    • Chatterjee, S.1    Grosshans, H.2
  • 59
    • 77955384888 scopus 로고    scopus 로고
    • Human polynucleotide phosphorylase selectively and preferentially degrades microRNA-221 in human melanoma cells
    • PMID:20547861
    • Das SK, Sokhi UK, Bhutia SK, Azab B, Su ZZ, Sarkar D, et al. Human polynucleotide phosphorylase selectively and preferentially degrades microRNA-221 in human melanoma cells. Proc Natl Acad Sci USA 2010; 107:11948-53; PMID:20547861; http://dx.doi.org/10.1073/pnas.0914143107.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 11948-11953
    • Das, S.K.1    Sokhi, U.K.2    Bhutia, S.K.3    Azab, B.4    Su, Z.Z.5    Sarkar, D.6
  • 60
    • 72549085095 scopus 로고    scopus 로고
    • Nuclear networking fashions pre-messenger RNA and primary microRNA transcripts for function
    • PMID:20004579
    • Pawlicki JM, Steitz JA. Nuclear networking fashions pre-messenger RNA and primary microRNA transcripts for function. Trends Cell Biol 2010; 20:52-61; PMID:20004579; http://dx.doi.org/10.1016/j.tcb.2009.10.004.
    • (2010) Trends Cell Biol , vol.20 , pp. 52-61
    • Pawlicki, J.M.1    Steitz, J.A.2
  • 61
    • 77952270043 scopus 로고    scopus 로고
    • MicroRNA expression after ionizing radiation in human endothelial cells
    • PMID:20346162
    • Wagner-Ecker M, Schwager C, Wirkner U, Abdollahi A, Huber PE. MicroRNA expression after ionizing radiation in human endothelial cells. Radiat Oncol 2010; 5:25; PMID:20346162; http://dx.doi.org/10.1186/1748-717X-5-25.
    • (2010) Radiat Oncol , vol.5 , pp. 25
    • Wagner-Ecker, M.1    Schwager, C.2    Wirkner, U.3    Abdollahi, A.4    Huber, P.E.5
  • 62
    • 70350398906 scopus 로고    scopus 로고
    • Identification of specific microRNAs responding to low and high dose gamma-irradiation in the human lymphoblast line IM9
    • PMID:19724866
    • Cha HJ, Seong KM, Bae S, Jung JH, Kim CS, Yang KH, et al. Identification of specific microRNAs responding to low and high dose gamma-irradiation in the human lymphoblast line IM9. Oncol Rep 2009; 22:863-8; PMID:19724866.
    • (2009) Oncol Rep , vol.22 , pp. 863-868
    • Cha, H.J.1    Seong, K.M.2    Bae, S.3    Jung, J.H.4    Kim, C.S.5    Yang, K.H.6
  • 63
    • 67649432381 scopus 로고    scopus 로고
    • Identification of ionizing radiation-responsive microRNAs in the IM9 human B lymphoblastic cell line
    • PMID:19424585
    • Cha HJ, Shin S, Yoo H, Lee EM, Bae S, Yang KH, et al. Identification of ionizing radiation-responsive microRNAs in the IM9 human B lymphoblastic cell line. Int J Oncol 2009; 34:1661-8; PMID:19424585.
    • (2009) Int J Oncol , vol.34 , pp. 1661-1668
    • Cha, H.J.1    Shin, S.2    Yoo, H.3    Lee, E.M.4    Bae, S.5    Yang, K.H.6
  • 64
    • 79952394030 scopus 로고    scopus 로고
    • MicroRNA dysregulation in human thyroid cells following exposure to ionizing radiation
    • PMID:21323591
    • Nikiforova MN, Gandhi M, Kelly L, Nikiforov YE. MicroRNA dysregulation in human thyroid cells following exposure to ionizing radiation. Thyroid 2011; 21:261-6; PMID:21323591; http://dx.doi.org/10.1089/thy.2010.0376.
    • (2011) Thyroid , vol.21 , pp. 261-266
    • Nikiforova, M.N.1    Gandhi, M.2    Kelly, L.3    Nikiforov, Y.E.4
  • 65
    • 79951500251 scopus 로고    scopus 로고
    • The ATM kinase induces microRNA biogenesis in the DNA damage response
    • PMID:21329876
    • Zhang X, Wan G, Berger FG, He X, Lu X. The ATM kinase induces microRNA biogenesis in the DNA damage response. Mol Cell 2011; 41:371-83; PMID:21329876; http://dx.doi.org/10.1016/j.molcel.2011.01.020.
    • (2011) Mol Cell , vol.41 , pp. 371-383
    • Zhang, X.1    Wan, G.2    Berger, F.G.3    He, X.4    Lu, X.5
  • 66
    • 67649445759 scopus 로고    scopus 로고
    • Alteration of miRNA profiles by ionizing radiation in A549 human non-small cell lung cancer cells
    • PMID:19513554
    • Shin S, Cha HJ, Lee EM, Lee SJ, Seo SK, Jin HO, et al. Alteration of miRNA profiles by ionizing radiation in A549 human non-small cell lung cancer cells. Int J Oncol 2009; 35:81-6; PMID:19513554.
    • (2009) Int J Oncol , vol.35 , pp. 81-86
    • Shin, S.1    Cha, H.J.2    Lee, E.M.3    Lee, S.J.4    Seo, S.K.5    Jin, H.O.6
  • 67
    • 67649449931 scopus 로고    scopus 로고
    • MicroRNAs are significantly influenced by p53 and radiation in HCT116 human colon carcinoma cells
    • PMID:19424583
    • Shin S, Cha HJ, Lee EM, Jung JH, Lee SJ, Park IC, et al. MicroRNAs are significantly influenced by p53 and radiation in HCT116 human colon carcinoma cells. Int J Oncol 2009; 34:1645-52; PMID:19424583.
    • (2009) Int J Oncol , vol.34 , pp. 1645-1652
    • Shin, S.1    Cha, H.J.2    Lee, E.M.3    Jung, J.H.4    Lee, S.J.5    Park, I.C.6
  • 68
    • 79953224859 scopus 로고    scopus 로고
    • MicroRNA expression profiles in human cancer cells after ionizing radiation
    • PMID:21453501
    • Niemoeller OM, Niyazi M, Corradini S, Zehentmayr F, Li M, Lauber K, et al. MicroRNA expression profiles in human cancer cells after ionizing radiation. Radiat Oncol 2011; 6:29; PMID:21453501; http://dx.doi.org/10.1186/1748-717X-6- 29.
    • (2011) Radiat Oncol , vol.6 , pp. 29
    • Niemoeller, O.M.1    Niyazi, M.2    Corradini, S.3    Zehentmayr, F.4    Li, M.5    Lauber, K.6
  • 69
    • 37049019490 scopus 로고    scopus 로고
    • MicroRNAs as potential agents to alter resistance to cytotoxic anticancer therapy
    • PMID:18056433
    • Weidhaas JB, Babar I, Nallur SM, Trang P, Roush S, Boehm M, et al. MicroRNAs as potential agents to alter resistance to cytotoxic anticancer therapy. Cancer Res 2007; 67:11111-6; PMID:18056433; http://dx.doi.org/10.1158/ 0008-5472.CAN-07-2858.
    • (2007) Cancer Res , vol.67 , pp. 11111-11116
    • Weidhaas, J.B.1    Babar, I.2    Nallur, S.M.3    Trang, P.4    Roush, S.5    Boehm, M.6
  • 70
    • 71849111080 scopus 로고    scopus 로고
    • Alterations in microRNA expression in stress-induced cellular senescence
    • PMID:19782699
    • Li G, Luna C, Qiu J, Epstein DL, Gonzalez P. Alterations in microRNA expression in stress-induced cellular senescence. Mech Ageing Dev 2009; 130:731-41; PMID:19782699; http://dx.doi.org/10.1016/j.mad.2009.09.002.
    • (2009) Mech Ageing Dev , vol.130 , pp. 731-741
    • Li, G.1    Luna, C.2    Qiu, J.3    Epstein, D.L.4    Gonzalez, P.5
  • 71
    • 68149161140 scopus 로고    scopus 로고
    • Ionizing radiation-induced oxidative stress alters miRNA expression
    • PMID:19633716
    • Simone NL, Soule BP, Ly D, Saleh AD, Savage JE, Degraff W, et al. Ionizing radiation-induced oxidative stress alters miRNA expression. PLoS One 2009; 4:e6377; PMID:19633716; http://dx.doi.org/10.1371/journal.pone.0006377.
    • (2009) PLoS One , vol.4
    • Simone, N.L.1    Soule, B.P.2    Ly, D.3    Saleh, A.D.4    Savage, J.E.5    Degraff, W.6
  • 72
    • 79960781245 scopus 로고    scopus 로고
    • Chemotherapy-induced modification of microRNA expression in esophageal cancer
    • PMID:21743970
    • Hummel R, Wang T, Watson DI, Michael MZ, Van der Hoek M, Haier J, et al. Chemotherapy-induced modification of microRNA expression in esophageal cancer. Oncol Rep 2011; 26:1011-7; PMID:21743970.
    • (2011) Oncol Rep , vol.26 , pp. 1011-1017
    • Hummel, R.1    Wang, T.2    Watson, D.I.3    Michael, M.Z.4    Van Der Hoek, M.5    Haier, J.6
  • 73
    • 80052391165 scopus 로고    scopus 로고
    • miRNA response to DNA damage
    • PMID:21741842
    • Wan G, Mathur R, Hu X, Zhang X, Lu X. miRNA response to DNA damage. Trends Biochem Sci 2011; 36:478-84; PMID:21741842; http://dx.doi.org/10.1016/j. tibs.2011.06.002.
    • (2011) Trends Biochem Sci , vol.36 , pp. 478-484
    • Wan, G.1    Mathur, R.2    Hu, X.3    Zhang, X.4    Lu, X.5
  • 74
    • 67649277689 scopus 로고    scopus 로고
    • The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs
    • PMID:19458619
    • Trabucchi M, Briata P, Garcia-Mayoral M, Haase AD, Filipowicz W, Ramos A, et al. The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs. Nature 2009; 459:1010-4; PMID:19458619; http://dx.doi.org/10.1038/ nature08025.
    • (2009) Nature , vol.459 , pp. 1010-1014
    • Trabucchi, M.1    Briata, P.2    Garcia-Mayoral, M.3    Haase, A.D.4    Filipowicz, W.5    Ramos, A.6
  • 75
    • 0034142325 scopus 로고    scopus 로고
    • Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53
    • PMID:10673500
    • Chehab NH, Malikzay A, Appel M, Halazonetis TD. Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53. Genes Dev 2000; 14:278-88; PMID:10673500.
    • (2000) Genes Dev , vol.14 , pp. 278-288
    • Chehab, N.H.1    Malikzay, A.2    Appel, M.3    Halazonetis, T.D.4
  • 76
    • 0034629072 scopus 로고    scopus 로고
    • DNA damage-induced activation of p53 by the checkpoint kinase Chk2
    • PMID:10710310
    • Hirao A, Kong YY, Matsuoka S, Wakeham A, Ruland J, Yoshida H, et al. DNA damage-induced activation of p53 by the checkpoint kinase Chk2. Science 2000; 287:1824-7; PMID:10710310; http://dx.doi.org/10.1126/science.287.5459.1824.
    • (2000) Science , vol.287 , pp. 1824-1827
    • Hirao, A.1    Kong, Y.Y.2    Matsuoka, S.3    Wakeham, A.4    Ruland, J.5    Yoshida, H.6
  • 77
    • 34250851115 scopus 로고    scopus 로고
    • A microRNA component of the p53 tumour suppressor network
    • PMID:17554337
    • He L, He X, Lim LP, de Stanchina E, Xuan Z, Liang Y, et al. A microRNA component of the p53 tumour suppressor network. Nature 2007; 447:1130-4; PMID:17554337; http://dx.doi.org/10.1038/nature05939.
    • (2007) Nature , vol.447 , pp. 1130-1134
    • He, L.1    He, X.2    Lim, L.P.3    De Stanchina, E.4    Xuan, Z.5    Liang, Y.6
  • 78
    • 84863344601 scopus 로고    scopus 로고
    • Phospho-ΔNp63α-dependent regulation of autophagic signaling through transcription and micro-RNA modulation
    • PMID:22356768
    • Huang Y, Guerrero-Preston R, Ratovitski EA. Phospho-ΔNp63α- dependent regulation of autophagic signaling through transcription and micro-RNA modulation. Cell Cycle 2012; 11:1247-59; PMID:22356768; http://dx.doi.org/10. 4161/cc.11.6.19670.
    • (2012) Cell Cycle , vol.11 , pp. 1247-1259
    • Huang, Y.1    Guerrero-Preston, R.2    Ratovitski, E.A.3
  • 79
    • 81855227722 scopus 로고    scopus 로고
    • Phospho-ΔNp63α/miR-885-3p axis in tumor cell life and cell death upon cisplatin exposure
    • PMID:22071691
    • Huang Y, Chuang AY, Ratovitski EA. Phospho-ΔNp63α/miR-885-3p axis in tumor cell life and cell death upon cisplatin exposure. Cell Cycle 2011; 10:3938-47; PMID:22071691; http://dx.doi.org/10.4161/cc.10.22.18107.
    • (2011) Cell Cycle , vol.10 , pp. 3938-3947
    • Huang, Y.1    Chuang, A.Y.2    Ratovitski, E.A.3
  • 80
    • 79958831395 scopus 로고    scopus 로고
    • Phospho-ΔNp63α is a key regulator of the cisplatin-induced microRNAome in cancer cells
    • PMID:21274007
    • Huang Y, Chuang A, Hao H, Talbot C, Sen T, Trink B, et al. Phospho-ΔNp63α is a key regulator of the cisplatin-induced microRNAome in cancer cells. Cell Death Differ 2011; 18:1220-30; PMID:21274007; http://dx.doi.org/10.1038/cdd.2010.188.
    • (2011) Cell Death Differ , vol.18 , pp. 1220-1230
    • Huang, Y.1    Chuang, A.2    Hao, H.3    Talbot, C.4    Sen, T.5    Trink, B.6
  • 81
    • 84861944845 scopus 로고    scopus 로고
    • BRCA1 regulates microRNA biogenesis via the DROSHA microprocessor complex
    • PMID:22492723
    • Kawai S, Amano A. BRCA1 regulates microRNA biogenesis via the DROSHA microprocessor complex. J Cell Biol 2012; 197:201-8; PMID:22492723; http://dx.doi.org/10.1083/jcb.201110008.
    • (2012) J Cell Biol , vol.197 , pp. 201-208
    • Kawai, S.1    Amano, A.2
  • 82
    • 77956390556 scopus 로고    scopus 로고
    • Radiation-induced micro-RNA modulation in glioblastoma cells differing in DNA-repair pathways
    • PMID:20380575
    • Chaudhry MA, Sachdeva H, Omaruddin RA. Radiation-induced micro-RNA modulation in glioblastoma cells differing in DNA-repair pathways. DNA Cell Biol 2010; 29:553-61; PMID:20380575; http://dx.doi.org/10.1089/dna.2009.0978.
    • (2010) DNA Cell Biol , vol.29 , pp. 553-561
    • Chaudhry, M.A.1    Sachdeva, H.2    Omaruddin, R.A.3
  • 83
    • 57349165798 scopus 로고    scopus 로고
    • DNA damage-induced upregulation of miR-709 in the germline downregulates BORIS to counteract aberrant DNA hypomethylation
    • PMID:19029807
    • Tamminga J, Kathiria P, Koturbash I, Kovalchuk O. DNA damage-induced upregulation of miR-709 in the germline downregulates BORIS to counteract aberrant DNA hypomethylation. Cell Cycle 2008; 7:3731-6; PMID:19029807; http://dx.doi.org/10.4161/cc.7.23.7186.
    • (2008) Cell Cycle , vol.7 , pp. 3731-3736
    • Tamminga, J.1    Kathiria, P.2    Koturbash, I.3    Kovalchuk, O.4
  • 84
    • 0141757460 scopus 로고    scopus 로고
    • MAPK pathways in radiation responses
    • PMID:12947395
    • Dent P, Yacoub A, Fisher PB, Hagan MP, Grant S. MAPK pathways in radiation responses. Oncogene 2003; 22:5885-96; PMID:12947395; http://dx.doi.org/10.1038/sj.onc.1206701.
    • (2003) Oncogene , vol.22 , pp. 5885-5896
    • Dent, P.1    Yacoub, A.2    Fisher, P.B.3    Hagan, M.P.4    Grant, S.5
  • 85
    • 48249114811 scopus 로고    scopus 로고
    • Phosphorylation of Argonaute 2 at serine-387 facilitates its localization to processing bodies
    • PMID:18476811
    • Zeng Y, Sankala H, Zhang X, Graves PR. Phosphorylation of Argonaute 2 at serine-387 facilitates its localization to processing bodies. Biochem J 2008; 413:429-36; PMID:18476811; http://dx.doi.org/10.1042/BJ20080599.
    • (2008) Biochem J , vol.413 , pp. 429-436
    • Zeng, Y.1    Sankala, H.2    Zhang, X.3    Graves, P.R.4
  • 86
    • 79953682552 scopus 로고    scopus 로고
    • Phosphorylation of human Argonaute proteins affects small RNA binding
    • PMID:21071408
    • Rüdel S, Wang Y, Lenobel R, Körner R, Hsiao HH, Urlaub H, et al. Phosphorylation of human Argonaute proteins affects small RNA binding. Nucleic Acids Res 2011; 39:2330-43; PMID:21071408; http://dx.doi.org/10.1093/ nar/gkq1032.
    • (2011) Nucleic Acids Res , vol.39 , pp. 2330-2343
    • Rüdel, S.1    Wang, Y.2    Lenobel, R.3    Körner, R.4    Hsiao, H.H.5    Urlaub, H.6
  • 87
    • 34249947699 scopus 로고    scopus 로고
    • ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
    • PMID:17525332
    • Matsuoka S, Ballif BA, Smogorzewska A, McDonald ER 3rd, Hurov KE, Luo J, et al. ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science 2007; 316:1160-6; PMID:17525332; http://dx.doi.org/10.1126/science.1140321.
    • (2007) Science , vol.316 , pp. 1160-1166
    • Matsuoka, S.1    Ballif, B.A.2    Smogorzewska, A.3    McDonald III, E.R.4    Hurov, K.E.5    Luo, J.6
  • 88
    • 77956896318 scopus 로고    scopus 로고
    • Oncogenic Wip1 phosphatase is inhibited by miR-16 in the DNA damage signaling pathway
    • PMID:20668064
    • Zhang X, Wan G, Mlotshwa S, Vance V, Berger FG, Chen H, et al. Oncogenic Wip1 phosphatase is inhibited by miR-16 in the DNA damage signaling pathway. Cancer Res 2010; 70:7176-86; PMID:20668064; http://dx.doi.org/10.1158/0008-5472. CAN-10-0697.
    • (2010) Cancer Res , vol.70 , pp. 7176-7186
    • Zhang, X.1    Wan, G.2    Mlotshwa, S.3    Vance, V.4    Berger, F.G.5    Chen, H.6
  • 89
    • 70349895582 scopus 로고    scopus 로고
    • Hypoxia-mediated regulation of Cdc25A phosphatase by p21 and miR-21
    • PMID:19738433
    • de Oliveira PE, Zhang L, Wang Z, Lazo JS. Hypoxia-mediated regulation of Cdc25A phosphatase by p21 and miR-21. Cell Cycle 2009; 8:3157-64; PMID:19738433; http://dx.doi.org/10.4161/cc.8.19.9704.
    • (2009) Cell Cycle , vol.8 , pp. 3157-3164
    • De Oliveira, P.E.1    Zhang, L.2    Wang, Z.3    Lazo, J.S.4
  • 90
    • 34547458550 scopus 로고    scopus 로고
    • p53-mediated activation of miRNA34 candidate tumor-suppressor genes
    • PMID:17656095
    • Bommer GT, Gerin I, Feng Y, Kaczorowski AJ, Kuick R, Love RE, et al. p53-mediated activation of miRNA34 candidate tumor-suppressor genes. Curr Biol 2007; 17:1298-307; PMID:17656095; http://dx.doi.org/10.1016/j.cub.2007.06.068.
    • (2007) Curr Biol , vol.17 , pp. 1298-1307
    • Bommer, G.T.1    Gerin, I.2    Feng, Y.3    Kaczorowski, A.J.4    Kuick, R.5    Love, R.E.6
  • 91
    • 77950447614 scopus 로고    scopus 로고
    • p38 MAPK/MK2-mediated induction of miR-34c following DNA damage prevents Myc-dependent DNA replication
    • PMID:20212154
    • Cannell IG, Kong YW, Johnston SJ, Chen ML, Collins HM, Dobbyn HC, et al. p38 MAPK/MK2-mediated induction of miR-34c following DNA damage prevents Myc-dependent DNA replication. Proc Natl Acad Sci USA 2010; 107:5375-80; PMID:20212154; http://dx.doi.org/10.1073/pnas.0910015107.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 5375-5380
    • Cannell, I.G.1    Kong, Y.W.2    Johnston, S.J.3    Chen, M.L.4    Collins, H.M.5    Dobbyn, H.C.6
  • 92
    • 77956305756 scopus 로고    scopus 로고
    • MicroRNA let-7a inhibits proliferation of human prostate cancer cells in vitro and in vivo by targeting E2F2 and CCND2
    • PMID:20418948
    • Dong Q, Meng P, Wang T, Qin W, Qin W, Wang F, et al. MicroRNA let-7a inhibits proliferation of human prostate cancer cells in vitro and in vivo by targeting E2F2 and CCND2. PLoS One 2010; 5:e10147; PMID:20418948; http://dx.doi.org/10.1371/journal.pone.0010147.
    • (2010) PLoS One , vol.5
    • Dong, Q.1    Meng, P.2    Wang, T.3    Qin, W.4    Qin, W.5    Wang, F.6
  • 93
    • 65449172038 scopus 로고    scopus 로고
    • let-7 Overexpression leads to an increased fraction of cells in G2/M, direct downregulation of Cdc34, and stabilization of Wee1 kinase in primary fibroblasts
    • PMID:19126550
    • Legesse-Miller A, Elemento O, Pfau SJ, Forman JJ, Tavazoie S, Coller HA. let-7 Overexpression leads to an increased fraction of cells in G2/M, direct downregulation of Cdc34, and stabilization of Wee1 kinase in primary fibroblasts. J Biol Chem 2009; 284:6605-9; PMID:19126550; http://dx.doi.org/10. 1074/jbc.C900002200.
    • (2009) J Biol Chem , vol.284 , pp. 6605-6609
    • Legesse-Miller, A.1    Elemento, O.2    Pfau, S.J.3    Forman, J.J.4    Tavazoie, S.5    Coller, H.A.6
  • 94
    • 43049133807 scopus 로고    scopus 로고
    • MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth
    • PMID:18379589
    • Schultz J, Lorenz P, Gross G, Ibrahim S, Kunz M. MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth. Cell Res 2008; 18:549-57; PMID:18379589; http://dx.doi.org/10.1038/cr.2008.45.
    • (2008) Cell Res , vol.18 , pp. 549-557
    • Schultz, J.1    Lorenz, P.2    Gross, G.3    Ibrahim, S.4    Kunz, M.5
  • 95
    • 69949098536 scopus 로고    scopus 로고
    • miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3′UTR microRNA recognition elements
    • PMID:19748357
    • Lal A, Navarro F, Maher CA, Maliszewski LE, Yan N, O'Day E, et al. miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3′UTR microRNA recognition elements. Mol Cell 2009; 35:610-25; PMID:19748357; http://dx.doi.org/10.1016/j.molcel. 2009.08.020.
    • (2009) Mol Cell , vol.35 , pp. 610-625
    • Lal, A.1    Navarro, F.2    Maher, C.A.3    Maliszewski, L.E.4    Yan, N.5    O'Day, E.6
  • 96
    • 79952413655 scopus 로고    scopus 로고
    • Down-regulation of microRNA 106b is involved in p21-mediated cell cycle arrest in response to radiation in prostate cancer cells
    • PMID:20878953
    • Li B, Shi XB, Nori D, Chao CK, Chen AM, Valicenti R, et al. Down-regulation of microRNA 106b is involved in p21-mediated cell cycle arrest in response to radiation in prostate cancer cells. Prostate 2011; 71:567-74; PMID:20878953; http://dx.doi.org/10.1002/pros.21272.
    • (2011) Prostate , vol.71 , pp. 567-574
    • Li, B.1    Shi, X.B.2    Nori, D.3    Chao, C.K.4    Chen, A.M.5    Valicenti, R.6
  • 97
    • 58149328931 scopus 로고    scopus 로고
    • miR-17 and miR-20a temper an E2F1-induced G1 checkpoint to regulate cell cycle progression
    • PMID:18836483
    • Pickering MT, Stadler BM, Kowalik TF. miR-17 and miR-20a temper an E2F1-induced G1 checkpoint to regulate cell cycle progression. Oncogene 2009; 28:140-5; PMID:18836483; http://dx.doi.org/10.1038/onc.2008.372.
    • (2009) Oncogene , vol.28 , pp. 140-145
    • Pickering, M.T.1    Stadler, B.M.2    Kowalik, T.F.3
  • 98
    • 51549115859 scopus 로고    scopus 로고
    • The miR-17-5p microRNA is a key regulator of the G1/S phase cell cycle transition
    • PMID:18700987
    • Cloonan N, Brown MK, Steptoe AL, Wani S, Chan WL, Forrest AR, et al. The miR-17-5p microRNA is a key regulator of the G1/S phase cell cycle transition. Genome Biol 2008; 9:R127; PMID:18700987; http://dx.doi.org/10.1186/gb-2008-9-8- r127.
    • (2008) Genome Biol , vol.9
    • Cloonan, N.1    Brown, M.K.2    Steptoe, A.L.3    Wani, S.4    Chan, W.L.5    Forrest, A.R.6
  • 99
    • 78049414216 scopus 로고    scopus 로고
    • Overexpression of miR-100 is responsible for the low-expression of ATM in the human glioma cell line: M059J
    • Amst PMID:20869334
    • Ng WL, Yan D, Zhang X, Mo YY, Wang Y. Overexpression of miR-100 is responsible for the low-expression of ATM in the human glioma cell line: M059J. DNA Repair (Amst) 2010; 9:1170-5; PMID:20869334; http://dx.doi.org/10.1016/j. dnarep.2010.08.007.
    • (2010) DNA Repair , vol.9 , pp. 1170-1175
    • Ng, W.L.1    Yan, D.2    Zhang, X.3    Mo, Y.Y.4    Wang, Y.5
  • 100
    • 76549127430 scopus 로고    scopus 로고
    • ATM is down-regulated by N-Myc-regulated microRNA-421
    • PMID:20080624
    • Hu H, Du L, Nagabayashi G, Seeger RC, Gatti RA. ATM is down-regulated by N-Myc-regulated microRNA-421. Proc Natl Acad Sci USA 2010; 107:1506-11; PMID:20080624; http://dx.doi.org/10.1073/pnas.0907763107.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 1506-1511
    • Hu, H.1    Du, L.2    Nagabayashi, G.3    Seeger, R.C.4    Gatti, R.A.5
  • 101
    • 77958133262 scopus 로고    scopus 로고
    • Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation
    • PMID:20617180
    • Yan D, Ng WL, Zhang X, Wang P, Zhang Z, Mo YY, et al. Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation. PLoS One 2010; 5:e11397; PMID:20617180; http://dx.doi.org/10.1371/journal.pone.0011397.
    • (2010) PLoS One , vol.5
    • Yan, D.1    Ng, W.L.2    Zhang, X.3    Wang, P.4    Zhang, Z.5    Mo, Y.Y.6
  • 102
    • 79955575393 scopus 로고    scopus 로고
    • Down-regulation of BRCA1 expression by miR-146a and miR-146b-5p in triple negative sporadic breast cancers
    • PMID:21472990
    • Garcia AI, Buisson M, Bertrand P, Rimokh R, Rouleau E, Lopez BS, et al. Down-regulation of BRCA1 expression by miR-146a and miR-146b-5p in triple negative sporadic breast cancers. EMBO Mol Med 2011; 3:279-90; PMID:21472990; http://dx.doi.org/10.1002/emmm.201100136.
    • (2011) EMBO Mol Med , vol.3 , pp. 279-290
    • Garcia, A.I.1    Buisson, M.2    Bertrand, P.3    Rimokh, R.4    Rouleau, E.5    Lopez, B.S.6
  • 103
    • 77951030494 scopus 로고    scopus 로고
    • Modulation of mismatch repair and genomic stability by miR-155
    • PMID:20351277
    • Valeri N, Gasparini P, Fabbri M, Braconi C, Veronese A, Lovat F, et al. Modulation of mismatch repair and genomic stability by miR-155. Proc Natl Acad Sci USA 2010; 107:6982-7; PMID:20351277; http://dx.doi.org/10.1073/pnas. 1002472107.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 6982-6987
    • Valeri, N.1    Gasparini, P.2    Fabbri, M.3    Braconi, C.4    Veronese, A.5    Lovat, F.6
  • 104
    • 84862798946 scopus 로고    scopus 로고
    • Modulation of microRNA processing by mismatch repair protein MutLá
    • PMID:22290424
    • Mao G, Lee S, Ortega J, Gu L, Li GM. Modulation of microRNA processing by mismatch repair protein MutLá. Cell Res 2012; 22:973-85; PMID:22290424; http://dx.doi.org/10.1038/cr.2012.18.
    • (2012) Cell Res , vol.22 , pp. 973-985
    • Mao, G.1    Lee, S.2    Ortega, J.3    Gu, L.4    Li, G.M.5
  • 105
    • 77953898940 scopus 로고    scopus 로고
    • A MicroRNA targeting dicer for metastasis control
    • PMID:20603000
    • Martello G, Rosato A, Ferrari F, Manfrin A, Cordenonsi M, Dupont S, et al. A MicroRNA targeting dicer for metastasis control. Cell 2010; 141:1195-207; PMID:20603000; http://dx.doi.org/10.1016/j.cell.2010.05.017.
    • (2010) Cell , vol.141 , pp. 1195-1207
    • Martello, G.1    Rosato, A.2    Ferrari, F.3    Manfrin, A.4    Cordenonsi, M.5    Dupont, S.6
  • 106
    • 54449097149 scopus 로고    scopus 로고
    • A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence
    • PMID:18812516
    • Forman JJ, Legesse-Miller A, Coller HA. A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence. Proc Natl Acad Sci USA 2008; 105:14879-84; PMID:18812516; http://dx.doi.org/10.1073/pnas.0803230105.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 14879-14884
    • Forman, J.J.1    Legesse-Miller, A.2    Coller, H.A.3
  • 107
    • 77952019174 scopus 로고    scopus 로고
    • Overexpression of dicer as a result of reduced let-7 MicroRNA levels contributes to increased cell proliferation of oral cancer cells
    • PMID:20232482
    • Jakymiw A, Patel RS, Deming N, Bhattacharyya I, Shah P, Lamont RJ, et al. Overexpression of dicer as a result of reduced let-7 MicroRNA levels contributes to increased cell proliferation of oral cancer cells. Genes Chromosomes Cancer 2010; 49:549-59; PMID:20232482; http://dx.doi.org/10.1002/ gcc.20765.
    • (2010) Genes Chromosomes Cancer , vol.49 , pp. 549-559
    • Jakymiw, A.1    Patel, R.S.2    Deming, N.3    Bhattacharyya, I.4    Shah, P.5    Lamont, R.J.6
  • 108
    • 55549127406 scopus 로고    scopus 로고
    • Let-7 regulates Dicer expression and constitutes a negative feedback loop
    • PMID:18700235
    • Tokumaru S, Suzuki M, Yamada H, Nagino M, Takahashi T. let-7 regulates Dicer expression and constitutes a negative feedback loop. Carcinogenesis 2008; 29:2073-7; PMID:18700235; http://dx.doi.org/10.1093/carcin/bgn187.
    • (2008) Carcinogenesis , vol.29 , pp. 2073-2077
    • Tokumaru, S.1    Suzuki, M.2    Yamada, H.3    Nagino, M.4    Takahashi, T.5
  • 109
    • 80053976182 scopus 로고    scopus 로고
    • HuR-dependent loading of miRNA RISC to the mRNA encoding the Ras-related small GTPase RhoB controls its translation during UV-induced apoptosis
    • PMID:21527938
    • Glorian V, Maillot G, Polès S, Iacovoni JS, Favre G, Vagner S. HuR-dependent loading of miRNA RISC to the mRNA encoding the Ras-related small GTPase RhoB controls its translation during UV-induced apoptosis. Cell Death Differ 2011; 18:1692-701; PMID:21527938; http://dx.doi.org/10.1038/cdd.2011.35.
    • (2011) Cell Death Differ , vol.18 , pp. 1692-1701
    • Glorian, V.1    Maillot, G.2    Polès, S.3    Iacovoni, J.S.4    Favre, G.5    Vagner, S.6
  • 110
    • 84864647205 scopus 로고    scopus 로고
    • Site-specific DICER and DROSHA RNA products control the DNA-damage response
    • PMID:22722852
    • Francia S, Michelini F, Saxena A, Tang D, de Hoon M, Anelli V, et al. Site-specific DICER and DROSHA RNA products control the DNA-damage response. Nature 2012; 488:231-5; PMID:22722852; http://dx.doi.org/10.1038/nature11179.
    • (2012) Nature , vol.488 , pp. 231-235
    • Francia, S.1    Michelini, F.2    Saxena, A.3    Tang, D.4    De Hoon, M.5    Anelli, V.6
  • 111
    • 55249113496 scopus 로고    scopus 로고
    • Radiation modulation of microRNA in prostate cancer cell lines
    • PMID:18668526
    • Josson S, Sung SY, Lao K, Chung LW, Johnstone PA. Radiation modulation of microRNA in prostate cancer cell lines. Prostate 2008; 68:1599-606; PMID:18668526; http://dx.doi.org/10.1002/pros.20827.
    • (2008) Prostate , vol.68 , pp. 1599-1606
    • Josson, S.1    Sung, S.Y.2    Lao, K.3    Chung, L.W.4    Johnstone, P.A.5
  • 112
    • 78649633708 scopus 로고    scopus 로고
    • Dysregulation of microRNA-34a expression causes drug-resistance to 5-FU in human colon cancer DLD-1 cells
    • PMID:21067862
    • Akao Y, Noguchi S, Iio A, Kojima K, Takagi T, Naoe T. Dysregulation of microRNA-34a expression causes drug-resistance to 5-FU in human colon cancer DLD-1 cells. Cancer Lett 2011; 300:197-204; PMID:21067862; http://dx.doi.org/10. 1016/j.canlet.2010.10.006.
    • (2011) Cancer Lett , vol.300 , pp. 197-204
    • Akao, Y.1    Noguchi, S.2    Iio, A.3    Kojima, K.4    Takagi, T.5    Naoe, T.6
  • 113
    • 78650423960 scopus 로고    scopus 로고
    • Context-dependent bidirectional regulation of the MutS homolog 2 by transforming growth factor β contributes to chemoresistance in breast cancer cells
    • PMID:21047769
    • Yu Y, Wang Y, Ren X, Tsuyada A, Li A, Liu LJ, et al. Context-dependent bidirectional regulation of the MutS homolog 2 by transforming growth factor β contributes to chemoresistance in breast cancer cells. Mol Cancer Res 2010; 8:1633-42; PMID:21047769; http://dx.doi.org/10.1158/1541-7786.MCR-10-0362.
    • (2010) Mol Cancer Res , vol.8 , pp. 1633-1642
    • Yu, Y.1    Wang, Y.2    Ren, X.3    Tsuyada, A.4    Li, A.5    Liu, L.J.6
  • 114
    • 78650500590 scopus 로고    scopus 로고
    • MicroRNA-21 induces resistance to 5-fluorouracil by down-regulating human DNA MutS homolog 2 (hMSH2)
    • PMID:21078976
    • Valeri N, Gasparini P, Braconi C, Paone A, Lovat F, Fabbri M, et al. MicroRNA-21 induces resistance to 5-fluorouracil by down-regulating human DNA MutS homolog 2 (hMSH2). Proc Natl Acad Sci USA 2010; 107:21098-103; PMID:21078976; http://dx.doi.org/10.1073/pnas.1015541107.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 21098-21103
    • Valeri, N.1    Gasparini, P.2    Braconi, C.3    Paone, A.4    Lovat, F.5    Fabbri, M.6
  • 115
    • 84871958603 scopus 로고    scopus 로고
    • Loss of microRNA-143/145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop
    • In press; PMID:22330136
    • Zhang J, Sun Q, Zhang Z, Ge S, Han ZG, Chen WT. Loss of microRNA-143/145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop. Oncogene 2012; In press; PMID:22330136; http://dx.doi.org/10.1038/onc.2012.28.
    • (2012) Oncogene
    • Zhang, J.1    Sun, Q.2    Zhang, Z.3    Ge, S.4    Han, Z.G.5    Chen, W.T.6
  • 116
    • 76749108600 scopus 로고    scopus 로고
    • Differential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links
    • PMID:20028736
    • Hicks JK, Chute CL, Paulsen MT, Ragland RL, Howlett NG, Guéranger Q, et al. Differential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links. Mol Cell Biol 2010; 30:1217-30; PMID:20028736; http://dx.doi.org/10.1128/MCB.00993-09.
    • (2010) Mol Cell Biol , vol.30 , pp. 1217-1230
    • Hicks, J.K.1    Chute, C.L.2    Paulsen, M.T.3    Ragland, R.L.4    Howlett, N.G.5    Guéranger, Q.6
  • 117
    • 79651471806 scopus 로고    scopus 로고
    • Two-step cleavage of hairpin RNA with 5′ overhangs by human DICER
    • PMID:21306637
    • Ando Y, Maida Y, Morinaga A, Burroughs AM, Kimura R, Chiba J, et al. Two-step cleavage of hairpin RNA with 5′ overhangs by human DICER. BMC Mol Biol 2011; 12:6; PMID:21306637; http://dx.doi.org/10.1186/1471-2199-12-6.
    • (2011) BMC Mol Biol , vol.12 , pp. 6
    • Ando, Y.1    Maida, Y.2    Morinaga, A.3    Burroughs, A.M.4    Kimura, R.5    Chiba, J.6
  • 118
    • 78149303249 scopus 로고    scopus 로고
    • MicroRNA sponges: Progress and possibilities
    • PMID:20855538
    • Ebert MS, Sharp PA. MicroRNA sponges: progress and possibilities. RNA 2010; 16:2043-50; PMID:20855538; http://dx.doi.org/10.1261/rna.2414110.
    • (2010) RNA , vol.16 , pp. 2043-2050
    • Ebert, M.S.1    Sharp, P.A.2
  • 119
    • 35348914716 scopus 로고    scopus 로고
    • Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430
    • PMID:17761850
    • Choi WY, Giraldez AJ, Schier AF. Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430. Science 2007; 318:271-4; PMID:17761850; http://dx.doi.org/10.1126/science.1147535.
    • (2007) Science , vol.318 , pp. 271-274
    • Choi, W.Y.1    Giraldez, A.J.2    Schier, A.F.3
  • 120
    • 42049103216 scopus 로고    scopus 로고
    • The let-7 microRNA reduces tumor growth in mouse models of lung cancer
    • PMID:18344688
    • Esquela-Kerscher A, Trang P, Wiggins JF, Patrawala L, Cheng A, Ford L, et al. The let-7 microRNA reduces tumor growth in mouse models of lung cancer. Cell Cycle 2008; 7:759-64; PMID:18344688; http://dx.doi.org/10.4161/cc.7.6.5834.
    • (2008) Cell Cycle , vol.7 , pp. 759-764
    • Esquela-Kerscher, A.1    Trang, P.2    Wiggins, J.F.3    Patrawala, L.4    Cheng, A.5    Ford, L.6
  • 121
    • 66449136951 scopus 로고    scopus 로고
    • Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model
    • PMID:19524505
    • Kota J, Chivukula RR, O'Donnell KA, Wentzel EA, Montgomery CL, Hwang HW, et al. Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell 2009; 137:1005-17; PMID:19524505; http://dx.doi.org/10.1016/ j.cell.2009.04.021.
    • (2009) Cell , vol.137 , pp. 1005-1017
    • Kota, J.1    Chivukula, R.R.2    O'Donnell, K.A.3    Wentzel, E.A.4    Montgomery, C.L.5    Hwang, H.W.6
  • 122
    • 2942707848 scopus 로고    scopus 로고
    • Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
    • PMID:15210113
    • Yang J, Mani SA, Donaher JL, Ramaswamy S, Itzykson RA, Come C, et al. Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 2004; 117:927-39; PMID:15210113; http://dx.doi.org/10.1016/j. cell.2004.06.006.
    • (2004) Cell , vol.117 , pp. 927-939
    • Yang, J.1    Mani, S.A.2    Donaher, J.L.3    Ramaswamy, S.4    Itzykson, R.A.5    Come, C.6
  • 123
    • 77950665077 scopus 로고    scopus 로고
    • Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model
    • PMID:20351690
    • Ma L, Reinhardt F, Pan E, Soutschek J, Bhat B, Marcusson EG, et al. Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model. Nat Biotechnol 2010; 28:341-7; PMID:20351690; http://dx.doi.org/10.1038/ nbt.1618.
    • (2010) Nat Biotechnol , vol.28 , pp. 341-347
    • Ma, L.1    Reinhardt, F.2    Pan, E.3    Soutschek, J.4    Bhat, B.5    Marcusson, E.G.6
  • 124
    • 24744464786 scopus 로고    scopus 로고
    • Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo
    • PMID:16091473
    • Takeshita F, Minakuchi Y, Nagahara S, Honma K, Sasaki H, Hirai K, et al. Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo. Proc Natl Acad Sci USA 2005; 102:12177-82; PMID:16091473; http://dx.doi.org/10.1073/pnas.0501753102.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 12177-12182
    • Takeshita, F.1    Minakuchi, Y.2    Nagahara, S.3    Honma, K.4    Sasaki, H.5    Hirai, K.6
  • 125
    • 84865062501 scopus 로고    scopus 로고
    • Molecular pathways: MicroRNAs as cancer therapeutics
    • PMID:22711704
    • Melo SA, Kalluri R. Molecular pathways: microRNAs as cancer therapeutics. Clin Cancer Res 2012; 18:4234-9; PMID:22711704; http://dx.doi.org/10.1158/1078- 0432.CCR-11-2010.
    • (2012) Clin Cancer Res , vol.18 , pp. 4234-4239
    • Melo, S.A.1    Kalluri, R.2
  • 126
    • 83255192141 scopus 로고    scopus 로고
    • Developing therapeutic microRNAs for cancer
    • PMID:21633392
    • Bader AG, Brown D, Stoudemire J, Lammers P. Developing therapeutic microRNAs for cancer. Gene Ther 2011; 18:1121-6; PMID:21633392; http://dx.doi.org/10.1038/gt.2011.79.
    • (2011) Gene Ther , vol.18 , pp. 1121-1126
    • Bader, A.G.1    Brown, D.2    Stoudemire, J.3    Lammers, P.4
  • 127
    • 84863726330 scopus 로고    scopus 로고
    • Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery
    • PMID:22659608
    • Lee H, Lytton-Jean AK, Chen Y, Love KT, Park AI, Karagiannis ED, et al. Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery. Nat Nanotechnol 2012; 7:389-93; PMID:22659608; http://dx.doi.org/10. 1038/nnano.2012.73.
    • (2012) Nat Nanotechnol , vol.7 , pp. 389-393
    • Lee, H.1    Lytton-Jean, A.K.2    Chen, Y.3    Love, K.T.4    Park, A.I.5    Karagiannis, E.D.6
  • 128
    • 84865955791 scopus 로고    scopus 로고
    • Folate-PEG-appended dendrimer conjugate with α-cyclodextrin as a novel cancer cell-selective siRNA delivery carrier
    • PMID:22873579
    • Arima H, Yoshimatsu A, Ikeda H, Ohyama A, Motoyama K, Higashi T, et al. Folate-PEG-appended dendrimer conjugate with α-cyclodextrin as a novel cancer cell-selective siRNA delivery carrier. Mol Pharm 2012; 9:2591-604; PMID:22873579; http://dx.doi.org/10.1021/mp300188f.
    • (2012) Mol Pharm , vol.9 , pp. 2591-2604
    • Arima, H.1    Yoshimatsu, A.2    Ikeda, H.3    Ohyama, A.4    Motoyama, K.5    Higashi, T.6
  • 129
    • 70449724791 scopus 로고    scopus 로고
    • MicroRNA responses and stress granule formation modulate the DNA damage response
    • PMID:19823042
    • Pothof J, Verkaik NS, Hoeijmakers JH, van Gent DC. MicroRNA responses and stress granule formation modulate the DNA damage response. Cell Cycle 2009; 8:3462-8; PMID:19823042; http://dx.doi.org/10.4161/cc.8.21.9835.
    • (2009) Cell Cycle , vol.8 , pp. 3462-3468
    • Pothof, J.1    Verkaik, N.S.2    Hoeijmakers, J.H.3    Van Gent, D.C.4
  • 130
    • 84862777377 scopus 로고    scopus 로고
    • Secreted microRNAs: A new form of intercellular communication
    • PMID:22260888
    • Chen X, Liang H, Zhang J, Zen K, Zhang CY. Secreted microRNAs: a new form of intercellular communication. Trends Cell Biol 2012; 22:125-32; PMID:22260888; http://dx.doi.org/10.1016/j.tcb.2011.12.001.
    • (2012) Trends Cell Biol , vol.22 , pp. 125-132
    • Chen, X.1    Liang, H.2    Zhang, J.3    Zen, K.4    Zhang, C.Y.5
  • 131
    • 80051779652 scopus 로고    scopus 로고
    • Plasma miRNA as biomarkers for assessment of total-body radiation exposure dosimetry
    • PMID:21857976
    • Cui W, Ma J, Wang Y, Biswal S. Plasma miRNA as biomarkers for assessment of total-body radiation exposure dosimetry. PLoS One 2011; 6:e22988; PMID:21857976; http://dx.doi.org/10.1371/journal.pone.0022988.
    • (2011) PLoS One , vol.6
    • Cui, W.1    Ma, J.2    Wang, Y.3    Biswal, S.4
  • 132
    • 79955632707 scopus 로고    scopus 로고
    • Radiation-induced micro-RNA expression changes in peripheral blood cells of radiotherapy patients
    • PMID:21420249
    • Templin T, Paul S, Amundson SA, Young EF, Barker CA, Wolden SL, et al. Radiation-induced micro-RNA expression changes in peripheral blood cells of radiotherapy patients. Int J Radiat Oncol Biol Phys 2011; 80:549-57; PMID:21420249; http://dx.doi.org/10.1016/j.ijrobp.2010.12.061.
    • (2011) Int J Radiat Oncol Biol Phys , vol.80 , pp. 549-557
    • Templin, T.1    Paul, S.2    Amundson, S.A.3    Young, E.F.4    Barker, C.A.5    Wolden, S.L.6
  • 133
    • 79959947888 scopus 로고    scopus 로고
    • Whole mouse blood microRNA as biomarkers for exposure to γ-rays and (56)Fe ion
    • PMID:21271940
    • Templin T, Amundson SA, Brenner DJ, Smilenov LB. Whole mouse blood microRNA as biomarkers for exposure to γ-rays and (56)Fe ion. Int J Radiat Biol 2011; 87:653-62; PMID:21271940; http://dx.doi.org/10.3109/09553002.2010. 549537.
    • (2011) Int J Radiat Biol , vol.87 , pp. 653-662
    • Templin, T.1    Amundson, S.A.2    Brenner, D.J.3    Smilenov, L.B.4
  • 134
    • 59149091637 scopus 로고    scopus 로고
    • MicroRNA regulation of DNA repair gene expression in hypoxic stress
    • PMID:19141645
    • Crosby ME, Kulshreshtha R, Ivan M, Glazer PM. MicroRNA regulation of DNA repair gene expression in hypoxic stress. Cancer Res 2009; 69:1221-9; PMID:19141645; http://dx.doi.org/10.1158/0008-5472.CAN-08-2516.
    • (2009) Cancer Res , vol.69 , pp. 1221-1229
    • Crosby, M.E.1    Kulshreshtha, R.2    Ivan, M.3    Glazer, P.M.4
  • 135
    • 84872190164 scopus 로고    scopus 로고
    • REV3L 3′UTR 460 T>C polymorphism in microRNA target sites contributes to lung cancer susceptibility
    • in press
    • Zhang S, Chen H, Zhao X, Cao J, Tong J, Lu J, et al. REV3L 3′UTR 460 T>C polymorphism in microRNA target sites contributes to lung cancer susceptibility. Oncogene 2012; in press; http://dx.doi.org/10.1038/onc.2012.32.
    • (2012) Oncogene
    • Zhang, S.1    Chen, H.2    Zhao, X.3    Cao, J.4    Tong, J.5    Lu, J.6
  • 136
    • 80053459622 scopus 로고    scopus 로고
    • Areca nut induces miR-23a and inhibits repair of DNA double-strand breaks by targeting FANCG
    • PMID:21750350
    • Tsai YS, Lin CS, Chiang SL, Lee CH, Lee KW, Ko YC. Areca nut induces miR-23a and inhibits repair of DNA double-strand breaks by targeting FANCG. Toxicol Sci 2011; 123:480-90; PMID:21750350; http://dx.doi.org/10.1093/toxsci/ kfr182.
    • (2011) Toxicol Sci , vol.123 , pp. 480-490
    • Tsai, Y.S.1    Lin, C.S.2    Chiang, S.L.3    Lee, C.H.4    Lee, K.W.5    Ko, Y.C.6
  • 137
    • 64349101658 scopus 로고    scopus 로고
    • MicroRNA-125b is a novel negative regulator of p53
    • PMID:19293287
    • Le MT, Teh C, Shyh-Chang N, Xie H, Zhou B, Korzh V, et al. MicroRNA-125b is a novel negative regulator of p53. Genes Dev 2009; 23:862-76; PMID:19293287; http://dx.doi.org/10.1101/gad.1767609.
    • (2009) Genes Dev , vol.23 , pp. 862-876
    • Le, M.T.1    Teh, C.2    Shyh-Chang, N.3    Xie, H.4    Zhou, B.5    Korzh, V.6
  • 138
    • 77953096272 scopus 로고    scopus 로고
    • Negative regulation of tumor suppressor p53 by microRNA miR-504
    • PMID:20542001
    • Hu W, Chan CS, Wu R, Zhang C, Sun Y, Song JS, et al. Negative regulation of tumor suppressor p53 by microRNA miR-504. Mol Cell 2010; 38:689-99; PMID:20542001; http://dx.doi.org/10.1016/j.molcel.2010.05.027.
    • (2010) Mol Cell , vol.38 , pp. 689-699
    • Hu, W.1    Chan, C.S.2    Wu, R.3    Zhang, C.4    Sun, Y.5    Song, J.S.6
  • 139
    • 79951812882 scopus 로고    scopus 로고
    • Negative regulation of the tumor suppressor p53 gene by microRNAs
    • PMID:20935678
    • Kumar M, Lu Z, Takwi AA, Chen W, Callander NS, Ramos KS, et al. Negative regulation of the tumor suppressor p53 gene by microRNAs. Oncogene 2011; 30:843-53; PMID:20935678; http://dx.doi.org/10.1038/onc.2010.457.
    • (2011) Oncogene , vol.30 , pp. 843-853
    • Kumar, M.1    Lu, Z.2    Takwi, A.A.3    Chen, W.4    Callander, N.S.5    Ramos, K.S.6
  • 140
    • 77957782177 scopus 로고    scopus 로고
    • Down-regulation of Wee1 kinase by a specific subset of microRNA in human sporadic pituitary adenomas
    • PMID:20668041
    • Butz H, Likó I, Czirják S, Igaz P, Khan MM, Zivkovic V, et al. Down-regulation of Wee1 kinase by a specific subset of microRNA in human sporadic pituitary adenomas. J Clin Endocrinol Metab 2010; 95:E181-91; PMID:20668041; http://dx.doi.org/10.1210/jc.2010-0581.
    • (2010) J Clin Endocrinol Metab , vol.95
    • Butz, H.1    Likó, I.2    Czirják, S.3    Igaz, P.4    Khan, M.M.5    Zivkovic, V.6
  • 141
    • 84055191603 scopus 로고    scopus 로고
    • Biogenesis of MiRNA-195 and its role in biogenesis, the cell cycle, and apoptosis
    • PMID:22190509
    • He JF, Luo YM, Wan XH, Jiang D. Biogenesis of MiRNA-195 and its role in biogenesis, the cell cycle, and apoptosis. J Biochem Mol Toxicol 2011; 25:404-8; PMID:22190509; http://dx.doi.org/10.1002/jbt.20396.
    • (2011) J Biochem Mol Toxicol , vol.25 , pp. 404-408
    • He, J.F.1    Luo, Y.M.2    Wan, X.H.3    Jiang, D.4
  • 142
    • 77954210384 scopus 로고    scopus 로고
    • MiR-322/424 and -503 are induced during muscle differentiation and promote cell cycle quiescence and differentiation by downregulation of Cdc25A
    • PMID:20462953
    • Sarkar S, Dey BK, Dutta A. MiR-322/424 and -503 are induced during muscle differentiation and promote cell cycle quiescence and differentiation by downregulation of Cdc25A. Mol Biol Cell 2010; 21:2138-49; PMID:20462953; http://dx.doi.org/10.1091/mbc.E10-01-0062.
    • (2010) Mol Biol Cell , vol.21 , pp. 2138-2149
    • Sarkar, S.1    Dey, B.K.2    Dutta, A.3
  • 143
    • 70350111289 scopus 로고    scopus 로고
    • miR-449a and miR-449b are direct transcriptional targets of E2F1 and negatively regulate pRb-E2F1 activity through a feedback loop by targeting CDK6 and CDC25A
    • PMID:19833767
    • Yang X, Feng M, Jiang X, Wu Z, Li Z, Aau M, et al. miR-449a and miR-449b are direct transcriptional targets of E2F1 and negatively regulate pRb-E2F1
    • (2009) Genes Dev , vol.23 , pp. 2388-2393
    • Yang, X.1    Feng, M.2    Jiang, X.3    Wu, Z.4    Li, Z.5    Aau, M.6
  • 144
    • 68149165414 scopus 로고    scopus 로고
    • HuR recruits let-7/RISC to repress c-Myc expression
    • PMID:19574298
    • Kim HH, Kuwano Y, Srikantan S, Lee EK, Martindale JL, Gorospe M. HuR recruits let-7/RISC to repress c-Myc expression. Genes Dev 2009; 23:1743-8; PMID:19574298; http://dx.doi.org/10.1101/gad.1812509.
    • (2009) Genes Dev , vol.23 , pp. 1743-1748
    • Kim, H.H.1    Kuwano, Y.2    Srikantan, S.3    Lee, E.K.4    Martindale, J.L.5    Gorospe, M.6
  • 145
    • 62549148270 scopus 로고    scopus 로고
    • p53 represses c-Myc through induction of the tumor suppressor miR-145
    • PMID:19202062
    • Sachdeva M, Zhu S, Wu F, Wu H, Walia V, Kumar S, et al. p53 represses c-Myc through induction of the tumor suppressor miR-145. Proc Natl Acad Sci USA 2009; 106:3207-12; PMID:19202062; http://dx.doi.org/10.1073/pnas.0808042106.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 3207-3212
    • Sachdeva, M.1    Zhu, S.2    Wu, F.3    Wu, H.4    Walia, V.5    Kumar, S.6
  • 146
    • 77951757309 scopus 로고    scopus 로고
    • The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression
    • PMID:20406979
    • Wong P, Iwasaki M, Somervaille TC, Ficara F, Carico C, Arnold C, et al. The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression. Cancer Res 2010; 70:3833-42; PMID:20406979; http://dx.doi.org/10.1158/0008-5472.CAN-09-3268.
    • (2010) Cancer Res , vol.70 , pp. 3833-3842
    • Wong, P.1    Iwasaki, M.2    Somervaille, T.C.3    Ficara, F.4    Carico, C.5    Arnold, C.6
  • 147
    • 34547791273 scopus 로고    scopus 로고
    • Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation
    • PMID:17627278
    • le Sage C, Nagel R, Egan DA, Schrier M, Mesman E, Mangiola A, et al. Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation. EMBO J 2007; 26:3699-708; PMID:17627278; http://dx.doi.org/10.1038/sj.emboj.7601790.
    • (2007) EMBO J , vol.26 , pp. 3699-3708
    • Le Sage, C.1    Nagel, R.2    Egan, D.A.3    Schrier, M.4    Mesman, E.5    Mangiola, A.6
  • 148
    • 79960431402 scopus 로고    scopus 로고
    • MicroRNA-372 is down-regulated and targets cyclin-dependent kinase 2 (CDK2) and cyclin A1 in human cervical cancer, which may contribute to tumorigenesis
    • PMID:21646351
    • Tian RQ, Wang XH, Hou LJ, Jia WH, Yang Q, Li YX, et al. MicroRNA-372 is down-regulated and targets cyclin-dependent kinase 2 (CDK2) and cyclin A1 in human cervical cancer, which may contribute to tumorigenesis. J Biol Chem 2011; 286:25556-63; PMID:21646351; http://dx.doi.org/10.1074/jbc.M111.221564.
    • (2011) J Biol Chem , vol.286 , pp. 25556-25563
    • Tian, R.Q.1    Wang, X.H.2    Hou, L.J.3    Jia, W.H.4    Yang, Q.5    Li, Y.X.6
  • 149
    • 79955836048 scopus 로고    scopus 로고
    • MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival
    • PMID:21233845
    • Afanasyeva EA, Mestdagh P, Kumps C, Vandesompele J, Ehemann V, Theissen J, et al. MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival. Cell Death Differ 2011; 18:974-84; PMID:21233845; http://dx.doi.org/10.1038/cdd.2010.164.
    • (2011) Cell Death Differ , vol.18 , pp. 974-984
    • Afanasyeva, E.A.1    Mestdagh, P.2    Kumps, C.3    Vandesompele, J.4    Ehemann, V.5    Theissen, J.6
  • 150
    • 78549288558 scopus 로고    scopus 로고
    • MicroRNA miR-302 inhibits the tumorigenecity of human pluripotent stem cells by coordinate suppression of the CDK2 and CDK4/6 cell cycle pathways
    • PMID:21062975
    • Lin SL, Chang DC, Ying SY, Leu D, Wu DT. MicroRNA miR-302 inhibits the tumorigenecity of human pluripotent stem cells by coordinate suppression of the CDK2 and CDK4/6 cell cycle pathways. Cancer Res 2010; 70:9473-82; PMID:21062975; http://dx.doi.org/10.1158/0008-5472.CAN-10-2746.
    • (2010) Cancer Res , vol.70 , pp. 9473-9482
    • Lin, S.L.1    Chang, D.C.2    Ying, S.Y.3    Leu, D.4    Wu, D.T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.