Protective effects of curcumin and quercetin during benzo(a)pyrene induced lung carcinogenesis in mice

European Review for Medical and Pharmacological Sciences

Volumn 19, Issue 9, 2015, Pages 1736-1743

  Liu, Y ^a,b   Wu, Y M ^b   Zhang, P Y ^a,b  

^a SOUTHEAST UNIVERSITY   (China)

^b XUZHOU CENTRAL HOSPITAL   (China)

Author keywords

Benzo(a)pyrene; Curcumin; Lung cancer; Mice; Quercetin

Indexed keywords

BENZO[A]PYRENE; CATALASE; CURCUMIN; CYTOCHROME B5; CYTOCHROME P450; DRINKING WATER; GLUTATHIONE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; QUERCETIN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; ANTIOXIDANT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; ENZYME ACTIVITY; LIPID PEROXIDATION; LUNG CARCINOGENESIS; LUNG WEIGHT; MALE; MOUSE; NONHUMAN; WEIGHT CHANGE; ANIMAL; DISEASE MODEL; DRUG EFFECTS; INBRED MOUSE STRAIN; LUNG; LUNG NEOPLASMS;

ANIMALS; ANTIOXIDANTS; BENZO(A)PYRENE; CURCUMIN; DISEASE MODELS, ANIMAL; LUNG; LUNG NEOPLASMS; MALE; MICE; MICE, INBRED STRAINS; QUERCETIN;

EID: 84942244019     PISSN: 11283602     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. SHI WY, LIU KD, XU SG, ZHANG JT, YU LL, XU KQ, ZHANG TF. Gene expression analysis of lung cancer. Eur Rev Med Pharmacol Sci 2014; 18: 217- 228.
2. DINSHAW KA, SHASTRI SS, PATIL SS. Cancer control programme in India: Challenges for the new millennium. Health Administrator 2005; 17: 10-13.
3. WU QP, MIN JX, JIANG L, LI JM, YAO K. Screening of biomarkers for lung cancer with gene expression profiling data. Eur Rev Med Pharmacol Sci 2013; 17: 3221-3228.
4. EISEN T, MATAKIDOU A, HOULSTON R, GELCAPS CONSORTIUM. Identification of low penetrance alleles for lung cancer: the genetic lung cancer predisposition study (GELCAPS). BMC Cancer 2008; 8:244.
5. VAN AGEN B, MAAS LM, ZWINGMANN IH, VAN SCHOOTEN FJ, KLEINJANS JC. B[a]P-DNA adduct for- mation and induction of human epithelial lung cell transformation. Environ Mol Mutagen 1997; 30: 287-292.
6. COOK JW, HEWETT CL, HIEGER IJ. The isolation of a cancer-producing hydrocarbon from coal tar. Parts I, II, and III. Chem Soc 1933; 1: 395-405.
7. KARLE YAGI H, SAYER, JERINA DM. Crystal and molecular structure of a benzo[a]pyrene 7, 8-diol 9, 10- epoxide N2-deoxyguanosine adduct: Absolute configuration and conformation. PNAS 2004; 101: 1433-1438.
8. SPORN MB, DUNLOP NM, NEWTON DL, SMITH JM. Prevention of chemical carcinogenesis by vitamin A and its synthetic analogs (retinoids). Fed Proc 1976; 35: 1332-1338.
9. KUMARAVEL M, SANKAR P, RUKKUMANI R. Antiproliferative effect of an analog of curcumin bis-1, 7-(2- hydroxyphenyl)-hepta-1, 6-diene-3, 5-dione in human breast cancer cells. Eur Rev Med Pharmacol Sci 2012; 16: 1900-1907.
10. CONNEY AH, LYSZ T, FERRARO T, ABIDI TF, MANCHAND PS, LASKIN JD, HUANG MT. Inhibitory effect of curcumin and some related dietary compounds on tumor promotion and arachidonic acid metabolism in mouse skin. Adv Enzyme Regulation 2008; 31:385-96.
11. LIN JK, LIN-SHIAU SY. Mechanisms of cancer chemoprevention by curcumin. Proc Natl Sci Counc Repub China B 2001; 2: 59-66.
12. ANNAPURNA A, ANSARI MA, MANJUNATH PM. Partial role of multiple pathways in infarct size limiting effect of quercetin and rutin against cerebral ischemia- reperfusion injury in rats. Eur Rev Med Pharmacol Sci 2013; 17: 491-500.
13. GUNNING WT, KRAMER PM, LUBET RA, STEELE VE, END DW, WOUTERS W, PEREIRA MA. Chemoprevention of benzo(a)pyrene induced lung tumors in mice by the farnesyltransferase inhibitor R1157771. Clin Cancer Res 2003; 9: 1927-1930.
14. DRIVER AS, KODAVANTI PR, MUNDI WR. Age related changes in reactive oxygen species in rat brain homogenates. Neurotoxicol Teratol 2000; 22: 175- 181.
15. WILLS ED. Mechanism of lipid peroxide formation in animal tissues; Biochem J 1966; 99: 667-676.
16. ELLMAN GL. Tissue sulphydryl groups; Archievs of Biochemistry Biophysics 1959; 82: 70-77.
17. LUCK H. In: methods of enzymatic analysis, Ed.: H.U. Bergmeyer, Academic Press, New York, 1971; pp. 885-893.
18. KONO Y. Generation of superoxide radical during auto oxidation of hydroxylamine and an assay for superoxide dismutase. Arch Biochem Biophys 1978; 186: 189-195.
19. CARLBERG I, MANNERVIK B. Glutathione reductase; Methods Enzymology 1985; 113: 484-490.
20. HABIG WH, PABST MJ, JACOBY WB. Glutathione-STransferase: The first enzymatic step in mercapturic acid formation. J Biol Chem 1974; 249: 7130- 7139.
21. LOWRY OH, ROSEBROUGH NJ, FARR AL, RANDALL RJ. Protein measurement with the Follin-phenol reagent. J Biol Chem 1951; 193: 265-275.
22. OMURA T, SATO R. The carbon monoxide-binding pigment of liver microsomes. II. Solubilisation, purification and properties. J Biol Chem 1964; 239: 2379-2385.
23. OMURA T, SATO R. The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature. J Biol Chem 1964b; 239: 2370-2378.
24. LIU RH. Potential synergy of phytochemicals in cancer prevention: mechanism of action. J Nutr 2004; 134: 3479S-3485S.
25. KAMARAJ S, VINODHKUMAR R, ANANDAKUMAR P, JAGAN S, RAMAKRISHNAN G, DEVAKI T. The effects of quercetin on antioxidant status and tumor markers in the lung and serum of mice treated with benzo(a)pyrene. Biol Pharm Bull 2007; 30: 2268- 2273.
26. MANTOVANI G. Randomised phase III clinical trial of 5 different arms of treatment on 332 patients with cancer cachexia. Eur Rev Med Pharmacol Sci 2010; 14: 292-301.
27. ZHOU GZ, CAO FL, CHANG JM, SUN GC, CHEN XB. Mechanism of curcumin analog MHMD-induced cell death in A549 lung cancer cells. Eur Rev Med Pharmacol Sci 2014; 18: 3134-3138.
28. CHUNG S, YAO H, CAITO S, HWANG JW, ARUNACHALAM G, RAHMAN I. Regulation of SIRT1 in cellular functions: Role of polyphenols. Arch Biochem Biophys 2010; 501: 79-90.
29. MUELLER MM. Inflammation in epithelial skin tumours: old stories and new ideas. Eur J Cancer 2006; 42: 735-744.
30. FARRON B, EVERS BM. Inflammation and the development of pancreatic cancer. Surgical Oncol 2002; 10: 153-169.
31. AGGARWAL BB. Targeting inflammation-induced obesity and metabolic diseases by curcumin and other nutraceuticals. Annu Rev Nutr 2010; 21:173-199.
32. KHANNA D, SETHI G, AHN KS, PANDEY MK, KUNNUMAKKARA AB, SUNG B, AGGARWAL A, AGGARWAL BB. Natural products as a gold mine for arthritis treatment. Curr Opin Pharmacol 2007; 7: 344-351.
33. SAMARTH RM, PANWAR M, KUMAR A. Modulatory effects of Mentha piperita on lung tumor incidence, genotoxicity, and oxidative stress in benzo[a]pyrene-treated Swiss albino mice. Environ Mol Mutagen 2006; 47: 192-198.
34. SUNDARESAN M, YU ZX, FERRANS VJ, IRANI K, FUIKEL T. Requirement for generation of hydrogen peroxide for platelet derived growth factor signal transduction. Science 1995; 270: 296-299.
35. RAJENDRAN P, VENUGOPAL R, EKAMBARAM G, AADITHYA A, SAKTHISEKARAN D. Rehabilitating activity of mangiferin in benzo(a)pyrene induced lung carcinogenesis. Asian J Biochem 2008; 3: 118- 125.
36. KOHLI K, ALI J, ANSARI M, RAHEMAN Z. Curcumin: A natural antiinflammatory agent. Indian J Pharmacol 2005; 37: 141-147.
37. RUIZ P, BRAUNE A, LZLWIMMER G, QUINTANILLA-FEND L, HALLER D. Quercetin inhibits TNF-induced NF-kB transcription factor recruitment to proinflammatory gene promoters in murine intestinal epithelial cells. J Nutr 2007; 137: 1208-1215.
38. JYOTI A, SETHI P, SHARMA D. Bacopa monniera prevents from aluminium neurotoxicity in the cerebral cortex of rat brain. J Ethnophramacol 2007; 111: 56-62.
39. RAMAKRISHNAN G, RAGHAVENDRAN HR, VINODHKUMAR R, DEVAKI T. Suppression of N-nitrosodiethylamine induced hepatocarcinogenesis by silymarin in rats. Chem Biol Interact 2006; 161: 104-114.
40. ALIA M, MATEOS R, RAMOS S, LECUMBERRI E, BRAVO L, GOYA L. Influence of quercetin and rutin on growth and antioxidant defense system of a human hepatoma cell line (HepG2). Eur J Nutr 2006; 45: 19- 28.
41. JAHANGIR T, SULTANA S. Benzo(a)pyrene-induced genotoxicity: Attenuation by farnesol in a mouse model. J Enzyme Inhib Med Chem 2008; 23: 888-894.
42. VALENTINE SP, LE NEDELEC MJ, MENZIES AR, SCANDLYN MJ, GOODIN MG, ROSENGREN RJ. Curcumin modulates drug metabolizing enzymes in the female Swiss Webster mouse. Life Sci 2006; 78: 2391- 2398.
43. GARG R, GUPTA S, MARU GB. Dietary curcumin modulates transcriptional regulators of phase I and phase II enzymes in benzo[a]pyrene-treated mice: mechanism of its anti-initiating action. Carcinogenesis 2008; 29: 1022-1032.
44. SU JM, LIN P, WANG CK, CHANG H. Overexpression of cytochrome P450 1B1 in advanced non-small cell lung cancer: A potential therapeutic target. Anticancer Res 2009; 29: 509-515.
45. LECLERC J, TOURNEL G, COURCOT-NGOUBO NGANGUE E, POTTIER N, LAFITTE JJ, JAILLARD S, MENSIER E, LHERMITTE M, BROLY F, LO-GUIDICE JM. Profiling gene expression of whole cytochrome P450 superfamily in human bronchial and peripheral lung tissues: Differential expression in non-small cell lung cancers. Biochimie 2010; 92: 292-306.
46. FINN RD, MCLAUGHLIN LA, RONSEAUX S, ROSEWELL I, HOUSTON JB, HENDERSON CJ, WOLF CR. Defining the in Vivo Role for cytochrome b5 in cytochrome P450 function through the conditional hepatic deletion of microsomal cytochrome b5. J Biol Chem 2008; 283: 31385-31393.