Metabolite signatures of exercise training in human skeletal muscle relate to mitochondrial remodelling and cardiometabolic fitness

Diabetologia

Volumn 57, Issue 11, 2014, Pages 2282-2295

  Huffman, Kim M ^a,b,c   Koves, Timothy R ^b,c   Hubal, Monica J ^d   Abouassi, Hiba ^b   Beri, Nina ^c   Bateman, Lori A ^b   Stevens, Robert D ^c   Ilkayeva, Olga R ^c   Hoffman, Eric P ^d   Muoio, Deborah M ^b,c   Kraus, William E ^b,c  

^a DURHAM VA MEDICAL CENTER   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

Author keywords

Acylcarnitines; Branched chain amino acids; Metabolomics; Physical activity; Skeletal muscle; Succinate

Indexed keywords

ACYLCARNITINE; AMINO ACID; CARNITINE; FATTY ACID; FUMARIC ACID; LACTIC ACID; MALIC ACID; MESSENGER RNA; PYRUVIC ACID; SUCCINIC ACID; TRICARBOXYLIC ACID; BRANCHED CHAIN AMINO ACID;

ADULT; AEROBIC EXERCISE; AGED; ARTICLE; CARDIOMETABOLIC FITNESS; CARDIORESPIRATORY FITNESS; CARDIOVASCULAR PARAMETERS; CARDIOVASCULAR RISK; ENERGY EXPENDITURE; FATTY ACID METABOLISM; FATTY ACID OXIDATION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; INSULIN SENSITIVITY; LIPID METABOLISM; MAJOR CLINICAL STUDY; MALE; MASS SPECTROMETRY; METABOLIC DISORDER; METABOLIC PARAMETERS; MUSCLE BIOPSY; MUSCLE EXERCISE; MUSCLE METABOLISM; MUSCLE MITOCHONDRION; NUTRITIONAL ASSESSMENT; OBESITY; OXIDATIVE PHOSPHORYLATION; PHYSICAL INACTIVITY; PREDICTION; PROTEIN EXPRESSION; RESISTANCE TRAINING; RISK FACTOR; SECONDARY ANALYSIS; SEDENTARY LIFESTYLE; SKELETAL MUSCLE; TRIACYLGLYCEROL BLOOD LEVEL; ADOLESCENT; ANALOGS AND DERIVATIVES; EXERCISE; METABOLISM; METABOLOMICS; MIDDLE AGED; PHYSIOLOGY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AMINO ACIDS, BRANCHED-CHAIN; CARNITINE; EXERCISE; FEMALE; HUMANS; MALE; METABOLOMICS; MIDDLE AGED; MITOCHONDRIA, MUSCLE; MUSCLE, SKELETAL; SUCCINIC ACID; YOUNG ADULT;

EID: 84919973700     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-014-3343-4     Document Type: Article

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