Statin-activated nuclear receptor PXR promotes SGK2 dephosphorylation by scaffolding PP2C to induce hepatic gluconeogenesis

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Gotoh, Saki ^a   Negishi, Masahiko ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMEDIATE EARLY PROTEIN; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); PHOSPHOPROTEIN PHOSPHATASE; PPM1A PROTEIN, HUMAN; PPM1B PROTEIN, HUMAN; PPM1G PROTEIN, HUMAN; PREGNANE X RECEPTOR; PROTEIN BINDING; PROTEIN PHOSPHATASE 2C; PROTEIN SERINE THREONINE KINASE; SERUM-GLUCOCORTICOID REGULATED KINASE; STEROID RECEPTOR;

AGONISTS; ANIMAL; BIOLOGICAL MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; GLUCONEOGENESIS; HUMAN; LIVER; LIVER CELL; METABOLISM; MOUSE; PROMOTER REGION; RNA INTERFERENCE;

ANIMALS; GENE EXPRESSION REGULATION; GLUCONEOGENESIS; HEPATOCYTES; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; IMMEDIATE-EARLY PROTEINS; LIVER; MICE; MODELS, BIOLOGICAL; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); PHOSPHOPROTEIN PHOSPHATASES; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN PHOSPHATASE 2C; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, STEROID; RNA INTERFERENCE; TRANSCRIPTION, GENETIC;

EID: 84942162684     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep14076     Document Type: Article

References (19)

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