Immunological Adaptations to Pregnancy in Women with Type 1 Diabetes

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Groen, Bart ^a   Van Der Wijk, Anne Eva ^a   Van Den Berg, Paul P ^a   Lefrandt, Joop D ^a   Van Den Berg, Gerrit ^a   Sollie, Krystina M ^a   De Vos, Paul ^a   Links, Thera P ^a   Faas, Marijke M ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTATION; ADULT; BLOOD; BLOOD CELL COUNT; FEMALE; HUMAN; IMMUNOLOGY; IMMUNOPHENOTYPING; INSULIN DEPENDENT DIABETES MELLITUS; LEUKOCYTE; METABOLISM; PREGNANCY; PREGNANCY DIABETES MELLITUS;

ADAPTATION, PHYSIOLOGICAL; ADULT; BLOOD CELL COUNT; DIABETES MELLITUS, TYPE 1; FEMALE; HUMANS; IMMUNOPHENOTYPING; LEUKOCYTES; PREGNANCY; PREGNANCY IN DIABETICS;

EID: 84942133059     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep13618     Document Type: Article

References (44)

1. Anderson, J. H., Jr et al. Reduction of postprandial hyperglycemia and frequency of hypoglycemia in IDDM patients on insulinanalog treatment. Multicenter Insulin Lispro Study Group. Diabetes 46, 265-270 (1997).
2. Evers, I. M., de Valk, H. W. & Visser, G. H. Risk of complications of pregnancy in women with type 1 diabetes: nationwide prospective study in the Netherlands. BMJ 328, 915 (2004).
3. Groen, B. et al. Aberrant Pregnancy Adaptations in the Peripheral Immune Response in Type 1 Diabetes: A Rat Model. PLoS One 8, e65490 (2013).
4. Veenstra van Nieuwenhoven, A. L., Heineman, M. J. & Faas, M. M. The immunology of successful pregnancy. Hum. Reprod. Update 9, 347-357 (2003).
5. Pijnenborg, R. Implantation and immunology: maternal inflammatory and immune cellular responses to implantation and trophoblast invasion. Reprod. Biomed. Online 4, Suppl 3, 14-17 (2002).
6. Szekeres-Bartho, J. Immunological relationship between the mother and the fetus. Int. Rev. Immunol. 21, 471-495 (2002).
7. Raghupathy, R. et al. Cytokine production by maternal lymphocytes during normal human pregnancy and in unexplained recurrent spontaneous abortion. Hum. Reprod. 15, 713-718 (2000).
8. Saito, S., Sakai, M., Sasaki, Y., Nakashima, A. & Shiozaki, A. Inadequate tolerance induction may induce pre-eclampsia. J. Reprod. Immunol. 76, 30-39 (2007).
9. Orsi, N. M. & Tribe, R. M. Cytokine networks and the regulation of uterine function in pregnancy and parturition. J. Neuroendocrinol. 20, 462-469 (2008).
10. Saito, S., Nakashima, A., Shima, T. & Ito, M. Th1/Th2/Th17 and regulatory T-cell paradigm in pregnancy. Am. J. Reprod. Immunol. 63, 601-610 (2010).
11. Veenstra van Nieuwenhoven, A. L. et al. Cytokine production in natural killer cells and lymphocytes in pregnant women compared with women in the follicular phase of the ovarian cycle. Fertil. Steril. 77, 1032-1037 (2002).
12. Borzychowski, A. M., Croy, B. A., Chan, W. L., Redman, C. W. & Sargent, I. L. Changes in systemic type 1 and type 2 immunity in normal pregnancy and pre-eclampsia may be mediated by natural killer cells. Eur. J. Immunol. 35, 3054-3063 (2005).
13. Sacks, G. P., Studena, K., Sargent, K. & Redman, C. W. Normal pregnancy and preeclampsia both produce inflammatory changes in peripheral blood leukocytes akin to those of sepsis. Am. J. Obstet. Gynecol. 179, 80-86 (1998).
14. van Nieuwenhoven, A. L., Moes, H., Heineman, M. J., Santema, J. & Faas, M. M. Cytokine production by monocytes, NK cells, and lymphocytes is different in preeclamptic patients as compared with normal pregnant women. Hypertens. Pregnancy 27, 207-224 (2008).
15. Ziegler-Heitbrock, L. & Hofer, T. P. Toward a refined definition of monocyte subsets. Front. Immunol. 4, 23 (2013).
16. Melgert, B. N. et al. Pregnancy and preeclampsia affect monocyte subsets in humans and rats. PLoS One 7, e45229 (2012).
17. Szebeni, A. et al. Th1 and Th2 cell responses of type 1 diabetes patients and healthy controls to human heat-shock protein 60 peptides AA437-460 and AA394-408. Inflamm. Res. 54, 415-419 (2005).
18. Haseda, F., Imagawa, A., Murase-Mishiba, Y., Terasaki, J. & Hanafusa, T. CD4(+ ) CD45RA(-) FoxP3high activated regulatory T cells are functionally impaired and related to residual insulin-secreting capacity in patients with type 1 diabetes. Clin. Exp. Immunol. 173, 207-216 (2013).
19. Rodacki, M. et al. Altered natural killer cells in type 1 diabetic patients. Diabetes 56, 177-185 (2007).
20. Gur, C. et al. The activating receptor NKp46 is essential for the development of type 1 diabetes. Nat. Immunol. 11, 121-128 (2010).
21. Fukui, A. et al. Correlation between natural cytotoxicity receptors and intracellular cytokine expression of peripheral blood NK cells in women with recurrent pregnancy losses and implantation failures. Am. J. Reprod. Immunol. 62, 371-380 (2009).
22. Fukui, A. et al. Changes of NK cells in preeclampsia. Am. J. Reprod. Immunol. 67, 278-286 (2012).
23. Robinson, D. P. & Klein, S. L. Pregnancy and pregnancy-associated hormones alter immune responses and disease pathogenesis. Horm. Behav. 62, 263-271 (2012).
24. Southcombe, J., Tannetta, D., Redman, C. & Sargent, I. The immunomodulatory role of syncytiotrophoblast microvesicles. PLoS One 6, e20245 (2011).
25. Redman, C. W. & Sargent, I. L. Circulating microparticles in normal pregnancy and pre-eclampsia. Placenta 29, Suppl A, S73-7 (2008).
26. Bakker, W., Eringa, E. C., Sipkema, P. & van Hinsbergh, V. W. Endothelial dysfunction and diabetes: roles of hyperglycemia, impaired insulin signaling and obesity. Cell Tissue Res. 335, 165-189 (2009).
27. Cipollone, F. et al. Enhanced soluble CD40 ligand contributes to endothelial cell dysfunction in vitro and monocyte activation in patients with diabetes mellitus: effect of improved metabolic control. Diabetologia 48, 1216-1224 (2005).
28. Pachot, A. et al. Messenger RNA expression of major histocompatibility complex class II genes in whole blood from septic shock patients. Crit. Care Med. 33, 31-8; discussion 236-7 (2005).
29. Shi, F. D. & Van Kaer, L. Reciprocal regulation between natural killer cells and autoreactive T cells. Nat. Rev. Immunol. 6, 751-760 (2006).
30. Moretta, A. et al. Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis. Annu. Rev. Immunol. 19, 197-223 (2001).
31. Nakae, S., Iwakura, Y., Suto, H. & Galli, S. J. Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17. J. Leukoc. Biol. 81, 1258-1268 (2007).
32. Mjosberg, J. et al. Systemic reduction of functionally suppressive CD4dimCD25highFoxp3+ Tregs in human second trimester pregnancy is induced by progesterone and 17beta-estradiol. J. Immunol. 183, 759-769 (2009).
33. Xiong, H., Zhou, C. & Qi, G. Proportional changes of CD4+ CD25+ Foxp3+ regulatory T cells in maternal peripheral blood during pregnancy and labor at term and preterm. Clin. Invest. Med. 33, E422 (2010).
34. Kuhnert, M., Strohmeier, R., Stegmuller, M. & Halberstadt, E. Changes in lymphocyte subsets during normal pregnancy. Eur. J. Obstet. Gynecol. Reprod. Biol. 76, 147-151 (1998).
35. Yokota, M. et al. Role of NKp46 expression in cytokine production by CD56-positive NK cells in the peripheral blood and the uterine endometrium. Am. J. Reprod. Immunol. 69, 202-211 (2013).
36. Guerrieri, D. et al. Serine leucocyte proteinase inhibitor-treated monocyte inhibits human CD4(+ ) lymphocyte proliferation. Immunology 133, 434-441 (2011).
37. Wittmann, S., Rothe, G., Schmitz, G. & Frohlich, D. Cytokine upregulation of surface antigens correlates to the priming of the neutrophil oxidative burst response. Cytometry A. 57, 53-62 (2004).
38. Faas, M. M., Spaans, F. & De Vos, P. Monocytes and macrophages in pregnancy and pre-eclampsia. Front. Immunol. 5, 298 (2014).
39. Wahabi, H. A., Alzeidan, R. A., Bawazeer, G. A., Alansari, L. A. & Esmaeil, S. A. Preconception care for diabetic women for improving maternal and fetal outcomes: a systematic review and meta-analysis. BMC Pregnancy Childbirth 10, 63 (2010).
40. Radder, J. K. & van Roosmalen, J. HbA1c in healthy, pregnant women. Neth. J. Med. 63, 256-259 (2005).
41. Norgaard, M. et al. Rheumatoid arthritis and birth outcomes: a Danish and Swedish nationwide prevalence study. J. Intern. Med. 268, 329-337 (2010).
42. Cervera, R., Font, J., Carmona, F. & Balasch, J. Pregnancy outcome in systemic lupus erythematosus: good news for the new millennium. Autoimmun. Rev. 1, 354-359 (2002).
43. Brown, M. A., Lindheimer, M. D., de Swiet, M., Van Assche, A. & Moutquin, J. M. The classification and diagnosis of the hypertensive disorders of pregnancy: statement from the International Society for the Study of Hypertension in Pregnancy (ISSHP). Hypertens. Pregnancy 20, IX-XIV (2001).
44. Visser, G. H., Eilers, P. H., Elferink-Stinkens, P. M., Merkus, H. M. & Wit, J. M. New Dutch reference curves for birthweight by gestational age. Early Hum. Dev. 85, 737-744 (2009).