Cytokine production in natural killer cells and lymphocytes in pregnant women compared with women in the follicular phase of the ovarian cycle

Fertility and Sterility

Volumn 77, Issue 5, 2002, Pages 1032-1037

  Veenstra van Nieuwenhoven, Angélique L ^a   Bouman, Annechien ^a   Moes, Henk ^b   Heineman, Maas Jan ^a   De Leij, Lou F M H ^b   Santema, Job ^c   Faas, Marijke M ^b  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

^c Medical Center   (Netherlands)

Author keywords

Cytokines; Lymphocytes; Natural killer cells; Pregnancy; Type 2 immune response

Indexed keywords

CALCIUM IONOPHORE; CD3 ANTIGEN; CD8 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; MONENSIN; PHORBOL 13 ACETATE 12 MYRISTATE;

ADULT; AMENORRHEA; ANALYTIC METHOD; ARTICLE; BLOOD SAMPLING; CELL ASSAY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; FEMALE; FLOW CYTOMETRY; FOLLICULAR PHASE; HELPER CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IN VITRO STUDY; LYMPHOCYTE; NATURAL KILLER CELL; NORMAL HUMAN; NULLIPARA; OUTPATIENT DEPARTMENT; OVARY CYCLE; PREGNANCY; PRIORITY JOURNAL; PROSPECTIVE STUDY; STAINING; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; TIME;

ADULT; AMENORRHEA; CYTOKINES; FEMALE; FOLLICULAR PHASE; HUMANS; KILLER CELLS, NATURAL; LEUKOCYTE COUNT; LYMPHOCYTES; PREGNANCY; PROSPECTIVE STUDIES; T-LYMPHOCYTES, CYTOTOXIC; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 0036260828     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0015-0282(02)02976-X     Document Type: Article

References (29)

1. Two types of murine helper T cell clone. Definition according to profiles of lymphokine activities and secreted proteins
2. Purified protein derivative of Mycobacterium tuberculosis and excretory-secretory antigen(s) of Toxocara canis expand in vitro human T cells with sable and opposite (type 1 T helper or type 2 T helper) profile of cytokine production
3. The expanding universe of T cell subsets-Th1 and Th2 and more
4. Cytokine production by CD16-CD56 bright natural killer cells in the human early pregnancy decidua
5. Flowcytometric visualisation of cytokine production by CD3-CD56+NK cells and CD3+CD56+NK-T cells in whole blood
6. Cytokine production by NK-lymphocytes in follicular and luteal phase of the ovarian cycle in humans
7. Production of IL-5 by human NK cells and regulation of IL-5 secretion by IL-4, IL-10 and IL-12
8. Cutting edge: Differentiation of human NK cells into NK1 and NK2 subsets
9. Bidirectional cytokine interactions in the maternal-fetal relationship: Is succesful pregnancy a Th2 phenomenon?
10. IL-10 prevents naturally occurring fetal loss in the CBA (DBA/2) mating combination and local defect in IL-10 production in this abortion-pron combination is occurred by in vivo injection of IFN-tau
11. Pregnancy impairs resistance of C57BL/6 mice to Leishmania major infection and causes decreased antigen specific IFN-γ responses an increased production of T helper 2 cytokines
12. T helper 1 response against Leishmania major in pregnant C57BL/6 mice increases implantation failure and fetal resorption. Correlations with increased IFN-γ and TNF and reduces IL10 production by placental cells
13. Th1 and Th2 cells: Different pattern of lymphokine secretion lead to different functional properties
14. Characterization of type 1 and type 2 cytokine production profile in physiologic and pathologic human pregnancy
15. Increased numbers of circulating interferon-gamma and interleukin-4-secreting cells during normal pregnancy
16. The immune response during the luteal phase of the ovarian cycle: A Th2-type response?
17. T-lymphocyte subsets during pregnancy and the menstrual cycle
18. Leukocytes of normal pregnant women
19. Les cellules granuleuses de muqueuses intestinale et uterine
20. Studies of natural killer cell activity in pregnancy. Analysis at single cell level
21. Progesterone-induced blocking factor inhibits degranulation of natural killer cells
22. Quantitative analysis of peripheral blood Th0, Th1, Th2 and the Th1:Th2 cell ratio during normal human pregnancy and preeclampsia
23. Shifts in the TH1/TH2 balance during human pregnancy correlate with apoptotic changes
24. Paternal leukocytes selectively increase secretion of IL-4 in peripheral blood during normal pregnancies: Demonstrated a novel one-way MLC measuring cytokine secretion
25. Progesterone favors the development of human T helper cells producing Th2-type cytokines and promotes both IL-4 production and membrane CD30 expression in established Th1 cell clones
26. Modulation of mouse anti-SRBC antibody responses by placental abstracts. II. Antigen specificity and regulatory role of B and T cell populations affected by two distinct placental fractions
27. Immunoregulation of host-versus-graft responses in the uterus
28. Th1-type immunity is incompatible with successful pregnancy
29. Immunological aspects of human implantation