JNK-dependent downregulation of FoxO1 is required to promote the survival of fibroblast-like synoviocytes in rheumatoid arthritis

Annals of the Rheumatic Diseases

Volumn 74, Issue 9, 2015, Pages 1763-1771

  Grabiec, Aleksander M ^a   Angiolilli, Chiara ^a   Hartkamp, Linda M ^a   Van Baarsen, Lisa G M ^a   Tak, Paul P ^a,b   Reedquist, Kris A ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIM PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1B; MESSENGER RNA; PROTEIN BCL XL; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR FKHR; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, HUMAN; FOXO3 PROTEIN, HUMAN; FOXO4 PROTEIN, HUMAN; IL1B PROTEIN, HUMAN; IL6 PROTEIN, HUMAN; INTERLEUKIN 1BETA; INTERLEUKIN 6; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; APOPTOSIS; ARTICLE; CELL CYCLE; CELL SURVIVAL; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY; DOWN REGULATION; FEMALE; FIBROBLAST LIKE SYNOVIOCYTE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; RNA DEGRADATION; SYNOVIOCYTE; CYTOLOGY; DRUG EFFECTS; FIBROBLAST; GENETICS; METABOLISM; MIDDLE AGED; SYNOVIUM;

ADULT; AGED; ARTHRITIS, RHEUMATOID; CELL SURVIVAL; DOWN-REGULATION; FEMALE; FIBROBLASTS; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; INTERLEUKIN-1BETA; INTERLEUKIN-6; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MIDDLE AGED; PROTO-ONCOGENE PROTEINS C-AKT; RNA, MESSENGER; SYNOVIAL MEMBRANE; TRANSCRIPTION FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84942099686     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2013-203610     Document Type: Article

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