Hepatitis C virus envelope glycoprotein E1 forms trimers at the surface of the virion

Journal of Virology

Volumn 89, Issue 20, 2015, Pages 10333-10346

  Falson, Pierre ^a   Bartosch, Birke ^a,b   Alsaleh, Khaled ^c   Tews, Birke Andrea ^c,f   Loquet, Antoine ^a,g   Ciczora, Yann ^c   Riva, Laura ^c   Montigny, Cédric ^d   Montpellier, Claire ^c   Duverlie, Gilles ^e   Pécheur, Eve Isabelle ^a   Maire, Marc le ^d   Cosset, François Loïc ^b   Dubuisson, Jean ^c   Penin, François ^a  

^a UNIVERSITÉ DE LYON   (France)

^b CENTRE INTERNATIONAL DE RECHERCHE EN INFECTIOLOGIE   (France)

^c UNIV LILLE   (France)

^d INSTITUTE FOR INTEGRATIVE BIOLOGY OF THE CELL I2BC   (France)

^e AMIENS UNIVERSITY HOSPITAL   (France)

^f FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

^g UNIVERSITÉ DE BORDEAUX   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD81 ANTIGEN; GLYCOPROTEIN E1; GLYCOPROTEIN E2; HETERODIMER; HOMODIMER; HOMOTRIMER; POLYMER; TRIMER; UNCLASSIFIED DRUG; E1 PROTEIN, HEPATITIS C VIRUS; GLYCOPROTEIN E2, HEPATITIS C VIRUS; HYBRID PROTEIN; PROTEIN BINDING; VIRUS ENVELOPE PROTEIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DISULFIDE BOND; EMBRYO; GENETIC CONSERVATION; GXXXG MOTIF; HEK293 CELL LINE; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; MOLECULAR MODEL; MOLECULAR STABILITY; NONHUMAN; OLIGOMERIZATION; PHYSICAL CHEMISTRY; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; TRANSMEMBRANE DOMAIN OF E1; TRANSMEMBRANE DOMAIN OF E2; TRIMERIZATION; VIRAL PHENOMENA AND FUNCTIONS; VIRION; VIRUS INFECTIVITY; VIRUS PARTICLE; VIRUS PSEUDOPARTICLE; WESTERN BLOTTING; CHEMICAL STRUCTURE; CHEMISTRY; ESCHERICHIA COLI; GENE EXPRESSION; GENETICS; HEPACIVIRUS; METABOLISM; MOLECULAR GENETICS; MUTATION; PROTEIN MULTIMERIZATION; PROTEIN STABILITY; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT; ULTRASTRUCTURE; VIRUS ASSEMBLY; VIRUS ENTRY;

AMINO ACID MOTIFS; BINDING SITES; ESCHERICHIA COLI; GENE EXPRESSION; HEPACIVIRUS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT; VIRAL ENVELOPE PROTEINS; VIRION; VIRUS ASSEMBLY; VIRUS INTERNALIZATION;

EID: 84942091135     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00991-15     Document Type: Article

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