Targeting of Topoisomerase I for Prognoses and Therapeutics of Camptothecin-Resistant Ovarian Cancer

PLoS ONE

Volumn 10, Issue 7, 2015, Pages

  Lee, Yu Chieh ^a   Lee, Chii Hong ^b   Tsai, Hsiang Ping ^c   An, Herng Wei ^a   Lee, Chi Ming ^a   Wu, Jen Chine ^d   Chen, Chien Shu ^e   Huang, Shih Hao ^f   Hwang, Jaulang ^c   Cheng, Kur Ta ^c   Leiw, Phui Ly ^b   Chen, Chi Long ^a,g   Lin, Chun Mao ^c  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^e CHINA MEDICAL UNIVERSITY   (Taiwan)

^f Taipei College of Maritime Technology   (Taiwan)

^g TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE KINASE; CAMPTOTHECIN; DNA; DNA TOPOISOMERASE; EVODIAMINE; ANTINEOPLASTIC AGENT; EVODAMINE; INDOLE ALKALOID; TOP1 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; BINDING SITE; BLOOD LEVEL; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; CARCINOGENESIS; CONTROLLED STUDY; DISEASE ACTIVITY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG TARGETING; ENZYME ACTIVITY; ENZYME ASSAY; FEMALE; FLOW CYTOMETRY; G1 PHASE CELL CYCLE CHECKPOINT; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; OVARY CANCER; OVERALL SURVIVAL; PROTEIN EXPRESSION; SURVIVAL RATE; TUMOR VOLUME; TUNEL ASSAY; ANIMAL; APOPTOSIS; CELL CYCLE; DRUG EFFECTS; DRUG RESISTANCE; DRUG SCREENING; ENZYMOLOGY; METABOLISM; OVARIAN NEOPLASMS; PATHOLOGY; TREATMENT OUTCOME; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CAMPTOTHECIN; CELL CYCLE; CELL LINE, TUMOR; DNA TOPOISOMERASES, TYPE I; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; INDOLE ALKALOIDS; MICE; OVARIAN NEOPLASMS; TREATMENT OUTCOME; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84942060624     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0132579     Document Type: Article

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