Identification of mutations at DNA topoisomerase I responsible for camptothecin resistance

Cancer Research

Volumn 57, Issue 8, 1997, Pages 1516-1522

  Wang, Leng Fang ^a,c   Ting, Chun Yuan ^a   Lo, Cheng Kai ^a   Su, Jin Shan ^a   Mickley, Lyn A ^d   Fojo, Antonio T ^d   Whang Peng, Jacqueline ^b   Hwang, Jaulang ^a  

^a INSTITUTE OF MOLECULAR BIOLOGY   (Taiwan)

^b INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMSACRINE; CAMPTOTHECIN; COLCHICINE; DNA TOPOISOMERASE; DNA TOPOISOMERASE INHIBITOR; DOXORUBICIN; EPIPODOPHYLLOTOXIN DERIVATIVE; ETOPOSIDE; GLYCINE; HOE 33342; ISOLEUCINE; MESSENGER RNA; TENIPOSIDE; THREONINE; VALINE; VINBLASTINE;

AMINO ACID SUBSTITUTION; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DNA DRUG COMPLEX; DNA SEQUENCE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; GENE MUTATION; HUMAN; HUMAN CELL; OVARY CANCER; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CAMPTOTHECIN; DNA TOPOISOMERASES, TYPE I; DNA, NEOPLASM; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; MUTAGENESIS; MUTATION; NEOPLASM PROTEINS; OVARIAN NEOPLASMS; POLYMERASE CHAIN REACTION; TRANSFECTION; TUMOR CELLS, CULTURED; YEASTS;

EID: 0030899190     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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