메뉴 건너뛰기




Volumn 10, Issue 7, 2015, Pages

Calorie restriction suppresses age- Dependent hippocampal transcriptional signatures

Author keywords

[No Author keywords available]

Indexed keywords

CALRETICULIN; CRE RECOMBINASE; HEAT SHOCK PROTEIN; KLOTHO PROTEIN; MESSENGER RNA; PREALBUMIN; PROTEIN DISULFIDE ISOMERASE; PROTEIN DISULFIDE ISOMERASE FAMILY A MEMBER 4; PROTEIN DISULFIDE ISOMERASE FAMILY A MEMBER 6; PROTEIN HSPA1B; PROTEIN HSPA5; PROTEOME; UNCLASSIFIED DRUG;

EID: 84942013348     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0133923     Document Type: Article
Times cited : (52)

References (50)
  • 1
    • 33645299025 scopus 로고    scopus 로고
    • Ageing and neuronal vulnerability
    • PMID: 16552414
    • Mattson MP, Magnus T. Ageing and neuronal vulnerability. Nat Rev Neurosci. 2006; 7: 278-294. doi:10.1038/nrn1886 PMID: 16552414.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 278-294
    • Mattson, M.P.1    Magnus, T.2
  • 2
    • 37349016848 scopus 로고    scopus 로고
    • Synaptic plasticity, memory and the hippocampus: A neural network approach to causality
    • PMID: 18094707
    • Neves G, Cooke SF, Bliss TVP. Synaptic plasticity, memory and the hippocampus: A neural network approach to causality. Nat Rev Neurosci. 2008; 9: 65-75. doi:10.1038/nrn2303 PMID: 18094707.
    • (2008) Nat Rev Neurosci , vol.9 , pp. 65-75
    • Neves, G.1    Cooke, S.F.2    Bliss, T.V.P.3
  • 3
    • 0030698871 scopus 로고    scopus 로고
    • Life and death of neurons in the aging brain
    • PMID: 9334292
    • Morrison JH, Hof PR. Life and death of neurons in the aging brain. Science. 1997; 278: 412-419. doi:10.1126/science.278.5337.412 PMID: 9334292.
    • (1997) Science , vol.278 , pp. 412-419
    • Morrison, J.H.1    Hof, P.R.2
  • 4
    • 0036454496 scopus 로고    scopus 로고
    • Selective vulnerability of corticocortical and hippocampal circuits in aging and Alzheimer's disease
    • PMID: 12143403
    • Morrison JH, Hof PR. Selective vulnerability of corticocortical and hippocampal circuits in aging and Alzheimer's disease. Prog Brain Res. 2002; 136: 467-486. doi:10.1016/S0079-6123(02)36039-4 PMID: 12143403.
    • (2002) Prog Brain Res , vol.136 , pp. 467-486
    • Morrison, J.H.1    Hof, P.R.2
  • 5
    • 59649128680 scopus 로고    scopus 로고
    • Hippocampal gene expression changes during age-related cognitive decline
    • PMID: 19133237
    • Pawlowski TL, Bellush LL, Wright AW, Walker JP, Colvin RA, Huentelman MJ. Hippocampal gene expression changes during age-related cognitive decline. Brain Res. 2009; 1256: 101-10. doi:10.1016/j.brainres.2008.12.039 PMID: 19133237.
    • (2009) Brain Res , vol.1256 , pp. 101-110
    • Pawlowski, T.L.1    Bellush, L.L.2    Wright, A.W.3    Walker, J.P.4    Colvin, R.A.5    Huentelman, M.J.6
  • 6
    • 2542637241 scopus 로고    scopus 로고
    • Altered hippocampal transcript profile accompanies an age-related spatial memory deficit in mice
    • PMID: 15169854
    • Verbitsky M, Yonan AL, Malleret G, Kandel ER, Gilliam TC, Pavlidis P. Altered hippocampal transcript profile accompanies an age-related spatial memory deficit in mice. Learn Mem. 2004; 11: 253-260. doi:10.1101/lm.68204 PMID: 15169854.
    • (2004) Learn Mem , vol.11 , pp. 253-260
    • Verbitsky, M.1    Yonan, A.L.2    Malleret, G.3    Kandel, E.R.4    Gilliam, T.C.5    Pavlidis, P.6
  • 7
    • 84877155965 scopus 로고    scopus 로고
    • Altered calcium metabolism in aging CA1 hippocampal pyramidal neurons
    • PMID: 23637181
    • Oh MM, Oliveira FA, Waters J, Disterhoft JF. Altered calcium metabolism in aging CA1 hippocampal pyramidal neurons. J Neurosci. 2013; 33: 7905-7911. doi:10.1523/JNEUROSCI.5457-12.2013 PMID: 23637181.
    • (2013) J Neurosci. , vol.33 , pp. 7905-7911
    • Oh, M.M.1    Oliveira, F.A.2    Waters, J.3    Disterhoft, J.F.4
  • 8
    • 73049090241 scopus 로고    scopus 로고
    • Differential NMDA receptor-dependent calcium loading and mitochondrial dysfunction in CA1 vs. CA3 hippocampal neurons
    • Stanika R, Winters C, Pivovarova N, Andrews SB. Differential NMDA receptor-dependent calcium loading and mitochondrial dysfunction in CA1 vs. CA3 hippocampal neurons. Neurobiol Dis. 2010; 37: 1- 20. doi:10.1016/j.nbd.2009.10.020.
    • (2010) Neurobiol Dis , vol.37 , pp. 1-20
    • Stanika, R.1    Winters, C.2    Pivovarova, N.3    Andrews, S.B.4
  • 9
    • 84859513533 scopus 로고    scopus 로고
    • The early events of Alzheimer's disease pathology: From mitochondrial dysfunction to BDNF axonal transport deficits
    • Ye X, Tai W, Zhang D. The early events of Alzheimer's disease pathology: from mitochondrial dysfunction to BDNF axonal transport deficits. Neurobiol Aging. 2012; 33: 1122.e1-10. doi:10.1016/j.neurobiolaging.2011.11.004.
    • (2012) Neurobiol Aging , vol.33 , Issue.1122 , pp. e1-e10
    • Ye, X.1    Tai, W.2    Zhang, D.3
  • 10
    • 23044488902 scopus 로고    scopus 로고
    • The yin and yang of neurotrophin action
    • PMID: 16062169
    • Lu B, Pang PT, Woo NH. The yin and yang of neurotrophin action. Nat Rev Neurosci. 2005; 6: 603- 614. doi:10.1038/nrn1726 PMID: 16062169.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 603-614
    • Lu, B.1    Pang, P.T.2    Woo, N.H.3
  • 11
    • 0036488190 scopus 로고    scopus 로고
    • Dietary restriction enhances neurotrophin expression and neurogenesis in the hippocampus of adult mice
    • PMID: 11905999
    • Lee J, Seroogy KB, Mattson MP. Dietary restriction enhances neurotrophin expression and neurogenesis in the hippocampus of adult mice. J Neurochem. 2002; 80: 539-547. doi:10.1046/j.0022-3042.2001.00747.x PMID: 11905999.
    • (2002) J Neurochem , vol.80 , pp. 539-547
    • Lee, J.1    Seroogy, K.B.2    Mattson, M.P.3
  • 12
    • 77956026310 scopus 로고    scopus 로고
    • Dietary manipulation and caloric restriction in the development of mouse models relevant to neurological diseases
    • PMID: 20472058
    • Schroeder JE, Richardson JC, Virley DJ. Dietary manipulation and caloric restriction in the development of mouse models relevant to neurological diseases. Biochim Biophys Acta. 2010; 1802: 840-846. doi:10.1016/j.bbadis.2010.04.007 PMID: 20472058.
    • (2010) Biochim Biophys Acta , vol.1802 , pp. 840-846
    • Schroeder, J.E.1    Richardson, J.C.2    Virley, D.J.3
  • 13
    • 0038305724 scopus 로고    scopus 로고
    • Calorie restriction and ketogenic diet diminish neuronal excitability in rat dentate gyrus in vivo
    • PMID: 12790887
    • Bough KJ, Schwartzkroin PA, Rho JM. Calorie restriction and ketogenic diet diminish neuronal excitability in rat dentate gyrus in vivo. Epilepsia. 2003; 44: 752-760. doi:10.1046/j.1528-1157.2003.55502.x PMID: 12790887.
    • (2003) Epilepsia , vol.44 , pp. 752-760
    • Bough, K.J.1    Schwartzkroin, P.A.2    Rho, J.M.3
  • 14
    • 24944435480 scopus 로고    scopus 로고
    • Caloric restriction prevents aging-associated changes in spike-mediated Ca2+ accumulation and the slow afterhyperpolarization in hippocampal CA1 pyramidal neurons
    • PMID: 16112472
    • Hemond P, Jaffe DB. Caloric restriction prevents aging-associated changes in spike-mediated Ca2+ accumulation and the slow afterhyperpolarization in hippocampal CA1 pyramidal neurons. Neuroscience. 2005; 135: 413-420. doi:10.1016/j.neuroscience.2005.05.044 PMID: 16112472.
    • (2005) Neuroscience , vol.135 , pp. 413-420
    • Hemond, P.1    Jaffe, D.B.2
  • 15
    • 0024448365 scopus 로고
    • Dietary restriction suppresses age-related changes in dendritic spines
    • PMID: 2682315
    • Moroi-Fetters SE, Mervis RF, London ED, Ingram DK. Dietary restriction suppresses age-related changes in dendritic spines. Neurobiol Aging. 1989; 10: 317-322. doi:10.1016/0197-4580(89)90042-0 PMID: 2682315.
    • (1989) Neurobiol Aging , vol.10 , pp. 317-322
    • Moroi-Fetters, S.E.1    Mervis, R.F.2    London, E.D.3    Ingram, D.K.4
  • 16
    • 84923480043 scopus 로고    scopus 로고
    • Reduction of β-amyloid and γ-secretase by calorie restriction in female Tg2576 mice
    • PMID: 25556162
    • Schafer MJ, Alldred MJ, Lee SH, Calhoun ME, Petkova E, Mathews PM, et al. Reduction of β-amyloid and γ-secretase by calorie restriction in female Tg2576 mice. Neurobiol Aging. 2015; 36: 1293-1302. doi:10.1016/j.neurobiolaging.2014.10.043 PMID: 25556162.
    • (2015) Neurobiol Aging , vol.36 , pp. 1293-1302
    • Schafer, M.J.1    Alldred, M.J.2    Lee, S.H.3    Calhoun, M.E.4    Petkova, E.5    Mathews, P.M.6
  • 17
    • 0000847978 scopus 로고    scopus 로고
    • Gene-expression profile of the ageing brain in mice
    • PMID: 10888876
    • Lee C, Weindruch R, Prolla T. Gene-expression profile of the ageing brain in mice. Nat Genet. 2000; 25: 294-297. doi:10.1038/77046 PMID: 10888876.
    • (2000) Nat Genet , vol.25 , pp. 294-297
    • Lee, C.1    Weindruch, R.2    Prolla, T.3
  • 18
    • 79251599573 scopus 로고    scopus 로고
    • Gene expression in the hippocampus: Regionally specific effects of aging and caloric restriction
    • PMID: 21055414
    • Zeier Z, Madorsky I, Xu Y, Ogle WO, Notterpek L, Foster TC. Gene expression in the hippocampus: regionally specific effects of aging and caloric restriction. Mech Ageing Dev. 2011; 132: 8-19. doi:10.1016/j.mad.2010.10.006 PMID: 21055414.
    • (2011) Mech Ageing Dev , vol.132 , pp. 8-19
    • Zeier, Z.1    Madorsky, I.2    Xu, Y.3    Ogle, W.O.4    Notterpek, L.5    Foster, T.C.6
  • 19
    • 0036232814 scopus 로고    scopus 로고
    • DNA microarray analysis of the aging brain
    • PMID: 11923192
    • Prolla T. DNA microarray analysis of the aging brain. Chem Senses. 2002; 27: 299-306. doi:10.1093/chemse/27.3.299 PMID: 11923192.
    • (2002) Chem Senses , vol.27 , pp. 299-306
    • Prolla, T.1
  • 20
    • 0038206578 scopus 로고    scopus 로고
    • Gene microarrays in hippocampal aging: Statistical profiling identifies novel processes correlated with cognitive impairment
    • PMID: 12736351
    • Blalock EM, Chen K-C, Sharrow K, Herman JP, Porter NM, Foster TC, et al. Gene microarrays in hippocampal aging: statistical profiling identifies novel processes correlated with cognitive impairment. J Neurosci. 2003; 23: 3807-3819. PMID: 12736351.
    • (2003) J Neurosci , vol.23 , pp. 3807-3819
    • Blalock, E.M.1    Chen, K.-C.2    Sharrow, K.3    Herman, J.P.4    Porter, N.M.5    Foster, T.C.6
  • 21
    • 33750522659 scopus 로고    scopus 로고
    • Changes in transcription within the CA1 field of the hippocampus are associated with age-related spatial learning impairments
    • PMID: 16829144
    • Burger C, López MC, Feller JA, Baker H V, Muzyczka N, Mandel RJ. Changes in transcription within the CA1 field of the hippocampus are associated with age-related spatial learning impairments. Neurobiol Learn Mem. 2007; 87: 21-41. doi:10.1016/j.nlm.2006.05.003 PMID: 16829144.
    • (2007) Neurobiol Learn Mem , vol.87 , pp. 21-41
    • Burger, C.1    López, M.C.2    Feller, J.A.3    Baker, H.V.4    Muzyczka, N.5    Mandel, R.J.6
  • 22
    • 72949087976 scopus 로고    scopus 로고
    • Changes in behavior and gene expression induced by caloric restriction in C57BL/6 mice
    • PMID: 19737990
    • Yamamoto Y, Tanahashi T, Kawai T, Chikahisa S, Katsuura S, Nishida K, et al. Changes in behavior and gene expression induced by caloric restriction in C57BL/6 mice. Physiol Genomics. 2009; 39: 227- 235. doi:10.1152/physiolgenomics.00082.2009 PMID: 19737990.
    • (2009) Physiol Genomics , vol.39 , pp. 227-235
    • Yamamoto, Y.1    Tanahashi, T.2    Kawai, T.3    Chikahisa, S.4    Katsuura, S.5    Nishida, K.6
  • 23
    • 0033933738 scopus 로고    scopus 로고
    • Expression profile of transcripts in Alzheimer's disease tangle-bearing CA1 neurons
    • PMID: 10894219
    • Ginsberg SD, Hemby SE, Lee VM-Y, Eberwine JH, Trojanowski JQ. Expression profile of transcripts in Alzheimer's disease tangle-bearing CA1 neurons. Ann Neurol. 2000; 48: 77-87. doi:10.1002/1531-8249(200007)48:1<77::AID-ANA12>3.0.CO;2-A PMID: 10894219.
    • (2000) Ann Neurol , vol.48 , pp. 77-87
    • Ginsberg, S.D.1    Hemby, S.E.2    Lee, V.M.-Y.3    Eberwine, J.H.4    Trojanowski, J.Q.5
  • 24
    • 57749195712 scopus 로고    scopus 로고
    • RNA-Seq: A revolutionary tool for transcriptomics
    • PMID: 19015660
    • Wang Z, Gerstein M, Snyder M. RNA-Seq: A revolutionary tool for transcriptomics. Nat Rev Genet. 2009; 10: 57-63. doi:10.1038/nrg2484 PMID: 19015660.
    • (2009) Nat Rev Genet , vol.10 , pp. 57-63
    • Wang, Z.1    Gerstein, M.2    Snyder, M.3
  • 25
    • 0037936789 scopus 로고    scopus 로고
    • Impact of aging on hippocampal function: Plasticity, network dynamics, and cognition
    • PMID: 12758108
    • Rosenzweig ES, Barnes CA. Impact of aging on hippocampal function: plasticity, network dynamics, and cognition. Prog Neurobiol. 2003; 69: 143-179. doi:10.1016/S0301-0082(02)00126-0 PMID: 12758108.
    • (2003) Prog Neurobiol , vol.69 , pp. 143-179
    • Rosenzweig, E.S.1    Barnes, C.A.2
  • 26
    • 0028122463 scopus 로고
    • Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease
    • PMID: 7916070
    • West M, Coleman P, Flood D, Troncoso J. Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease. Lancet. 1994; 344: 769-772. doi:10.1016/S0140-6736(94)92338-8 PMID: 7916070.
    • (1994) Lancet , vol.344 , pp. 769-772
    • West, M.1    Coleman, P.2    Flood, D.3    Troncoso, J.4
  • 27
    • 84940575866 scopus 로고    scopus 로고
    • Expression profile analysis of vulnerable CA1 pyramidal neurons in young middle-aged Ts65Dn mice
    • In Press
    • Alldred MJ, Lee SH, Petkova E, Ginsberg SD. Expression profile analysis of vulnerable CA1 pyramidal neurons in young middle-aged Ts65Dn mice. Brain Struct Funct. 2015;In Press doi:10.1007/s00429-014-0839-0.
    • (2015) Brain Struct Funct
    • Alldred, M.J.1    Lee, S.H.2    Petkova, E.3    Ginsberg, S.D.4
  • 28
    • 84923497374 scopus 로고    scopus 로고
    • Caloric restriction attenuates ß-amyloid neuropathology in a mouse model of Alzheimer's disease
    • Wang J, Ho L, Qin W, Rocher A, Seror I, Humala N, et al. Caloric restriction attenuates ß-amyloid neuropathology in a mouse model of Alzheimer's disease. FASEB J. 2005; 18: 1-18. http://www.fasebj.org/content/19/6/659.short.
    • (2005) FASEB J , vol.18 , pp. 1-18
    • Wang, J.1    Ho, L.2    Qin, W.3    Rocher, A.4    Seror, I.5    Humala, N.6
  • 29
    • 0027075042 scopus 로고
    • Neurotrophin expression in rat hippocampal slices: A stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mRNAs
    • PMID: 1463608
    • Patterson SL, Grover LM, Schwartzkroin PA, Bothwell M. Neurotrophin expression in rat hippocampal slices: A stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mRNAs. Neuron. 1992; 9: 1081-1088. http://www.ncbi.nlm.nih.gov/pubmed/1463608 PMID: 1463608.
    • (1992) Neuron , vol.9 , pp. 1081-1088
    • Patterson, S.L.1    Grover, L.M.2    Schwartzkroin, P.A.3    Bothwell, M.4
  • 30
    • 0027087233 scopus 로고
    • Long-term potentiation is lost in aged rats but preserved by calorie restriction
    • PMID: 1337284
    • Hori N, Hirotsu I, Davis P, Carpenter D. Long-term potentiation is lost in aged rats but preserved by calorie restriction. Neuroreport. 1992; 3: 1085-1088. http://journals.lww.com/neuroreport/Abstract/1992/12000/Long-term-potentiation-is-lost-in-aged-rats-but.13.aspx PMID: 1337284.
    • (1992) Neuroreport , vol.3 , pp. 1085-1088
    • Hori, N.1    Hirotsu, I.2    Davis, P.3    Carpenter, D.4
  • 31
    • 40449100030 scopus 로고    scopus 로고
    • Direct multiplexed measurement of gene expression with color-coded probe pairs
    • PMID: 18278033
    • Geiss GK, Bumgarner RE, Birditt B, Dahl T, Dowidar N, Dunaway DL, et al. Direct multiplexed measurement of gene expression with color-coded probe pairs. Nat Biotechnol. 2008; 26: 317-325. doi:10.1038/nbt1385 PMID: 18278033.
    • (2008) Nat Biotechnol , vol.26 , pp. 317-325
    • Geiss, G.K.1    Bumgarner, R.E.2    Birditt, B.3    Dahl, T.4    Dowidar, N.5    Dunaway, D.L.6
  • 32
    • 41549156809 scopus 로고    scopus 로고
    • Morphological and biochemical signs of age-related neurodegenerative changes in klotho mutant mice
    • PMID: 18343589
    • Shiozaki M, Yoshimura K, Shibata M, Koike M, Matsuura N, Uchiyama Y, et al. Morphological and biochemical signs of age-related neurodegenerative changes in klotho mutant mice. Neuroscience. 2008; 152: 924-941. doi:10.1016/j.neuroscience.2008.01.032 PMID: 18343589.
    • (2008) Neuroscience , vol.152 , pp. 924-941
    • Shiozaki, M.1    Yoshimura, K.2    Shibata, M.3    Koike, M.4    Matsuura, N.5    Uchiyama, Y.6
  • 33
    • 34347364708 scopus 로고    scopus 로고
    • Accelerated Abeta deposition in APPswe/PS1deltaE9 mice with hemizygous deletions of TTR (transthyretin)
    • PMID: 17596449
    • Choi SH, Leight SN, Lee VM-Y, Li T, Wong PC, Johnson JA, et al. Accelerated Abeta deposition in APPswe/PS1deltaE9 mice with hemizygous deletions of TTR (transthyretin). J Neurosci. 2007; 27: 7006-7010. doi:10.1523/JNEUROSCI.1919-07.2007 PMID: 17596449.
    • (2007) J Neurosci , vol.27 , pp. 7006-7010
    • Choi, S.H.1    Leight, S.N.2    Lee, V.M.-Y.3    Li, T.4    Wong, P.C.5    Johnson, J.A.6
  • 34
    • 0033517366 scopus 로고    scopus 로고
    • Genetic enhancement of learning and memory in mice
    • PMID: 10485705
    • Tang YP, Shimizu E, Dube GR, Rampon C, Kerchner GA, Zhuo M, et al. Genetic enhancement of learning and memory in mice. Nature. 1999; 401: 63-69. doi:10.1038/43432 PMID: 10485705.
    • (1999) Nature , vol.401 , pp. 63-69
    • Tang, Y.P.1    Shimizu, E.2    Dube, G.R.3    Rampon, C.4    Kerchner, G.A.5    Zhuo, M.6
  • 35
    • 0037102726 scopus 로고    scopus 로고
    • N-methyl-d-aspartate receptor subunit NR2A and NR2B messenger RNA levels are altered in the hippocampus and entorhinal cortex in Alzheimer's disease
    • PMID: 12127670
    • Bi H, Sze C. N-methyl-d-aspartate receptor subunit NR2A and NR2B messenger RNA levels are altered in the hippocampus and entorhinal cortex in Alzheimer's disease. J Neurol Sci. 2002; 200: 11- 18. http://www.sciencedirect.com/science/article/pii/S0022510X02000874 PMID: 12127670.
    • (2002) J Neurol Sci , vol.200 , pp. 11-18
    • Bi, H.1    Sze, C.2
  • 36
    • 0028365919 scopus 로고
    • AMPA/kainate receptor gene expression in normal and Alzheimer's disease hippocampus
    • PMID: 7969894
    • Pellegrini-Giampietro D, Bennett M, Zukin R. AMPA/kainate receptor gene expression in normal and Alzheimer's disease hippocampus. Neuroscience. 1994; 61: 41-49. http://www.sciencedirect.com/science/article/pii/0306452294900582 PMID: 7969894.
    • (1994) Neuroscience , vol.61 , pp. 41-49
    • Pellegrini-Giampietro, D.1    Bennett, M.2    Zukin, R.3
  • 37
    • 0034708587 scopus 로고    scopus 로고
    • Driving AMPA Receptors into Synapses by LTP and CaMKII: Requirement for GluR1 and PDZ Domain Interaction
    • PMID: 10731148
    • Hayashi Y, Shi S, Esteban JA, Piccini A, Poncer J, Malinow R. Driving AMPA Receptors into Synapses by LTP and CaMKII: Requirement for GluR1 and PDZ Domain Interaction. Science. 2000; 287: 2262- 2267. doi:10.1126/science.287.5461.2262 PMID: 10731148.
    • (2000) Science , vol.287 , pp. 2262-2267
    • Hayashi, Y.1    Shi, S.2    Esteban, J.A.3    Piccini, A.4    Poncer, J.5    Malinow, R.6
  • 38
    • 0034738147 scopus 로고    scopus 로고
    • Caloric restriction prevents age-related deficits in LTP and in NMDA receptor expression
    • PMID: 10891595
    • Eckles-Smith K, Clayton D, Bickford P, Browning MD. Caloric restriction prevents age-related deficits in LTP and in NMDA receptor expression. Brain Res Mol Brain Res. 2000; 78: 154-162. http://www.ncbi.nlm.nih.gov/pubmed/10891595 PMID: 10891595.
    • (2000) Brain Res Mol Brain Res , vol.78 , pp. 154-162
    • Eckles-Smith, K.1    Clayton, D.2    Bickford, P.3    Browning, M.D.4
  • 39
    • 84863295841 scopus 로고    scopus 로고
    • Corticotrophin releasing factor accelerates neuropathology and cognitive decline in a mouse model of Alzheimer's disease
    • PMID: 22045495
    • Dong H, Murphy KM, Meng L, Montalvo-Ortiz J, Zeng Z, Kolber BJ, et al. Corticotrophin releasing factor accelerates neuropathology and cognitive decline in a mouse model of Alzheimer's disease. J Alzheimers Dis. 2012; 28: 579-592. doi:10.3233/JAD-2011-111328 PMID: 22045495.
    • (2012) J Alzheimers Dis , vol.28 , pp. 579-592
    • Dong, H.1    Murphy, K.M.2    Meng, L.3    Montalvo-Ortiz, J.4    Zeng, Z.5    Kolber, B.J.6
  • 40
    • 80053654553 scopus 로고    scopus 로고
    • Chronic stress exacerbates tau pathology, neurodegeneration, and cognitive performance through a corticotropin-releasing factor receptor-dependent mechanism in a transgenic mouse model of tauopathy
    • PMID: 21976528
    • Carroll JC, Iba M, Bangasser DA, Valentino RJ, James MJ, Brunden KR, et al. Chronic stress exacerbates tau pathology, neurodegeneration, and cognitive performance through a corticotropin-releasing factor receptor-dependent mechanism in a transgenic mouse model of tauopathy. J Neurosci. 2011; 31: 14436-14449. doi:10.1523/JNEUROSCI.3836-11.2011 PMID: 21976528.
    • (2011) J Neurosci , vol.31 , pp. 14436-14449
    • Carroll, J.C.1    Iba, M.2    Bangasser, D.A.3    Valentino, R.J.4    James, M.J.5    Brunden, K.R.6
  • 41
    • 11144243412 scopus 로고    scopus 로고
    • Modulation of neurodegeneration by molecular chaperones
    • PMID: 15611723
    • Muchowski PJ, Wacker JL. Modulation of neurodegeneration by molecular chaperones. Nat Rev Neurosci. 2005; 6: 11-22. doi:10.1038/nrn1587 PMID: 15611723.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 11-22
    • Muchowski, P.J.1    Wacker, J.L.2
  • 43
    • 0032475957 scopus 로고    scopus 로고
    • The chaperone BiP/GRP78 binds to amyloid precursor protein and decreases Abeta40 and Abeta42 secretion
    • PMID: 9748217
    • Yang Y, Turner RS, Gaut JR. The chaperone BiP/GRP78 binds to amyloid precursor protein and decreases Abeta40 and Abeta42 secretion. J Biol Chem. 1998; 273: 25552-25555. http://www.ncbi.nlm.nih.gov/pubmed/9748217 PMID: 9748217.
    • (1998) J Biol Chem , vol.273 , pp. 25552-25555
    • Yang, Y.1    Turner, R.S.2    Gaut, J.R.3
  • 44
    • 1242274389 scopus 로고    scopus 로고
    • Heat shock protein 70 participates in the neuroprotective response to intracellularly expressed beta-amyloid in neurons
    • PMID: 14973234
    • Magrané J, Smith RC, Walsh K, Querfurth HW. Heat shock protein 70 participates in the neuroprotective response to intracellularly expressed beta-amyloid in neurons. J Neurosci. 2004; 24: 1700-1706. doi:10.1523/JNEUROSCI.4330-03.2004 PMID: 14973234.
    • (2004) J Neurosci , vol.24 , pp. 1700-1706
    • Magrané, J.1    Smith, R.C.2    Walsh, K.3    Querfurth, H.W.4
  • 45
    • 0030724491 scopus 로고    scopus 로고
    • Mutation of the mouse klotho gene leads to a syndrome resembling ageing
    • PMID: 9363890
    • Kuro-o M, Matsumura Y, Aizawa H, Kawaguchi H, Suga T, Utsugi T, et al. Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Nature. 1997; 390: 45-51. doi:10.1038/36285 PMID: 9363890.
    • (1997) Nature , vol.390 , pp. 45-51
    • Kuro-O, M.1    Matsumura, Y.2    Aizawa, H.3    Kawaguchi, H.4    Suga, T.5    Utsugi, T.6
  • 46
    • 24944481544 scopus 로고    scopus 로고
    • Suppression of aging in mice by the hormone klotho
    • PMID: 16123266
    • Kurosu H. Suppression of aging in mice by the hormone klotho. Science. 2005; 309: 1829-1833. doi:10.1126/science.1112766 PMID: 16123266.
    • (2005) Science , vol.309 , pp. 1829-1833
    • Kurosu, H.1
  • 47
    • 84922572242 scopus 로고    scopus 로고
    • Life extension factor klotho prevents mortality and enhances cognition in hAPP transgenic mice
    • PMID: 25673831
    • Dubal DB, Zhu L, Sanchez PE, Worden K, Broestl L, Johnson E, et al. Life extension factor klotho prevents mortality and enhances cognition in hAPP transgenic mice. J Neurosci. 2015; 35: 2358-2371. doi:10.1523/JNEUROSCI.5791-12.2015 PMID: 25673831.
    • (2015) J Neurosci , vol.35 , pp. 2358-2371
    • Dubal, D.B.1    Zhu, L.2    Sanchez, P.E.3    Worden, K.4    Broestl, L.5    Johnson, E.6
  • 48
    • 84865761463 scopus 로고    scopus 로고
    • Small-molecule Klotho enhancers as novel treatment of neurodegeneration
    • PMID: 22924505
    • Abraham C, Chen C, Cuny G, Glicksman M, Zeldich E. Small-molecule Klotho enhancers as novel treatment of neurodegeneration. Future Med Chem. 2012; 4: 1671-1679. doi:10.4155/fmc.12.134 PMID: 22924505.
    • (2012) Future Med Chem , vol.4 , pp. 1671-1679
    • Abraham, C.1    Chen, C.2    Cuny, G.3    Glicksman, M.4    Zeldich, E.5
  • 49
    • 4444255624 scopus 로고    scopus 로고
    • Neutralization of transthyretin reverses the neuroprotective effects of secreted amyloid precursor protein (APP) in APPSW mice resulting in tau phosphorylation and loss of hippocampal neurons: Support for the amyloid hypothesis
    • PMID: 15342738
    • Stein TD, Anders NJ, DeCarli C, Chan SL, Mattson MP, Johnson JA. Neutralization of transthyretin reverses the neuroprotective effects of secreted amyloid precursor protein (APP) in APPSW mice resulting in tau phosphorylation and loss of hippocampal neurons: support for the amyloid hypothesis. J Neurosci. 2004; 24: 7707-7717. doi:10.1523/JNEUROSCI.2211-04.2004 PMID: 15342738.
    • (2004) J Neurosci , vol.24 , pp. 7707-7717
    • Stein, T.D.1    Anders, N.J.2    DeCarli, C.3    Chan, S.L.4    Mattson, M.P.5    Johnson, J.A.6
  • 50
    • 40649096849 scopus 로고    scopus 로고
    • Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Abeta toxicity
    • PMID: 18272491
    • Buxbaum JN, Ye Z, Reixach N, Friske L, Levy C, Das P, et al. Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Abeta toxicity. Proc Natl Acad Sci U S A. 2008; 105: 2681-2686. doi:10.1073/pnas.0712197105 PMID: 18272491.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 2681-2686
    • Buxbaum, J.N.1    Ye, Z.2    Reixach, N.3    Friske, L.4    Levy, C.5    Das, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.