TCR affinity for thymoproteasome-dependent positively selecting peptides conditions antigen responsiveness in CD8+ T cells

Nature Immunology

Volumn 16, Issue 10, 2015, Pages 1069-1076

  Takada, Kensuke ^a   Van Laethem, Francois ^b   Xing, Yan ^c   Akane, Kazuyuki ^d   Suzuki, Haruhiko ^d   Murata, Shigeo ^e   Tanaka, Keiji ^f   Jameson, Stephen C ^c   Singer, Alfred ^b   Takahama, Yousuke ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b NATIONAL CANCER INSTITUTE   (United States)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^d NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e UNIVERSITY OF TOKYO   (Japan)

^f TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD5 ANTIGEN; CD69 ANTIGEN; CHEMOKINE RECEPTOR CCR7; PEPTIDE; PROTEASOME; T LYMPHOCYTE RECEPTOR; THYMOPROTEASOME; TYROSINE; UNCLASSIFIED DRUG; LYMPHOCYTE ANTIGEN RECEPTOR;

ANIMAL CELL; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; BONE MARROW CELL; CD8+ T LYMPHOCYTE; CELL PROLIFERATION; CELL SELECTION; CELL STIMULATION; FLOW CYTOMETRY; HISTOCOMPATIBILITY COMPLEX; IMMUNE RESPONSE; IN VITRO STUDY; LISTERIA MONOCYTOGENES; LISTERIOSIS; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR AFFINITY; THYMOCYTE; THYMUS; ANIMAL; ENZYMOLOGY; IMMUNOLOGY;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; FLOW CYTOMETRY; MICE; PEPTIDES; PROTEASOME ENDOPEPTIDASE COMPLEX; RECEPTORS, ANTIGEN, T-CELL; THYMUS GLAND;

EID: 84941995472     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3237     Document Type: Article

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