Emetine inhibits migration and invasion of human non-small-cell lung cancer cells via regulation of ERK and p38 signaling pathways

Chemico-Biological Interactions

Volumn 242, Issue , 2015, Pages 25-33

  Kim, Ji Hyun ^a   Cho, Eun Byul ^a   Lee, Jongsung ^b   Jung, Okkeun ^a   Ryu, Byung Jun ^c   Kim, Seong Hwan ^c   Cho, Jae Youl ^b   Ryou, Chongsuk ^d   Lee, Sang Yeol ^a  

^a Gachon University   (South Korea)

^b Sungkyunkwan University   (South Korea)

^c Korea Research Institute of Chemical Technology   (South Korea)

^d Hanyang University   (South Korea)

Author keywords

Emetine; ERK; Human non small cell lung cancer; Matrix metalloproteinases; Metastasis; p38

Indexed keywords

BETA CATENIN; EMETINE; GELATINASE A; GELATINASE B; MATRIX METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MYC PROTEIN; STRESS ACTIVATED PROTEIN KINASE; CTNNB1 PROTEIN, HUMAN;

A549 CELL LINE; ARTICLE; CANCER CELL; CELL INVASION; CELL SPREADING; CONTROLLED STUDY; DOWN REGULATION; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REGULATION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; MIGRATION INHIBITION; NON SMALL CELL LUNG CANCER; SIGNAL TRANSDUCTION; CARCINOMA, NON-SMALL-CELL LUNG; CELL MOTION; DRUG EFFECTS; LUNG NEOPLASMS; METABOLISM; MOLECULARLY TARGETED THERAPY; PATHOLOGY; TUMOR CELL LINE;

BETA CATENIN; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; CELL MOVEMENT; EMETINE; HUMANS; LUNG NEOPLASMS; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MOLECULAR TARGETED THERAPY; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-MYC; SIGNAL TRANSDUCTION;

EID: 84941963131     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2015.08.014     Document Type: Article

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