Essential role of transient receptor potential M8 (TRPM8) in a model of acute cold-induced urinary urgency

European Urology

Volumn 68, Issue 4, 2015, Pages 655-661

  Uvin, Pieter ^a,b,c   Franken, Jan ^a,b,c   Pinto, Silvia ^a,c   Rietjens, Roma ^a,b,c   Grammet, Luc ^a,c   Deruyver, Yves ^a,b,c   Alpizar, Yeranddy A ^a,c   Talavera, Karel ^a,c   Vennekens, Rudi ^a,c   Everaerts, Wouter ^a,b,c   De Ridder, Dirk ^b,c   Voets, Thomas ^a,c  

^a LABORATORY OF MOLECULAR AND CELLULAR SIGNALING   (Belgium)

^b SKELETAL BIOLOGY AND ENGINEERING RESEARCH CENTER   (Belgium)

^c TRP Research Platform Leuven   (Belgium)

Author keywords

Cold sensing; TRPM8; Urinary urgency

Indexed keywords

ACETONE; N (3 AMINOPROPYL) 2 [[(3 METHYLPHENYL)METHYL]OXY] N (2 THIENYLMETHYL)BENZAMIDE; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; TRANSIENT RECEPTOR POTENTIAL CHANNEL AFFECTING AGENT; TRANSIENT RECEPTOR POTENTIAL CHANNEL M8; UNCLASSIFIED DRUG; BENZAMIDE DERIVATIVE; N-(3-AMINOPROPYL)-2-(((3-METHYLPHENYL) METHYL)OXY)-N-(2-THIENYLMETHYL)BENZAMIDE HYDROCHLORIDE SALT; THIOPHENE DERIVATIVE; TRANSIENT RECEPTOR POTENTIAL CHANNEL M; TRPM8 PROTEIN, MOUSE; TRPM8 PROTEIN, RAT;

ACUTE COLD INDUCED URGENCY; ACUTE DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLADDER CONTRACTION; BLADDER PRESSURE; C57BL 6 MOUSE; COLD INJURY; CONTROLLED STUDY; CYSTOMETRY; FEMALE; HIND PAW; MICTURITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SPRAGUE DAWLEY RAT; URINARY URGENCY; ANIMAL; ANTAGONISTS AND INHIBITORS; BLADDER; C57BL MOUSE; COLD; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; GENETICS; INDUCED HYPOTHERMIA; INNERVATION; INTRAPERITONEAL DRUG ADMINISTRATION; KNOCKOUT MOUSE; METABOLISM; PATHOPHYSIOLOGY; PRESSURE; REFLEX; SIGNAL TRANSDUCTION; SKIN; TIME FACTOR; URINARY INCONTINENCE, URGE; URODYNAMICS;

ANIMALS; BENZAMIDES; COLD TEMPERATURE; DISEASE MODELS, ANIMAL; FEMALE; HYPOTHERMIA, INDUCED; INJECTIONS, INTRAPERITONEAL; MICE, INBRED C57BL; MICE, KNOCKOUT; PRESSURE; RATS, SPRAGUE-DAWLEY; REFLEX; SIGNAL TRANSDUCTION; SKIN; THIOPHENES; TIME FACTORS; TRPM CATION CHANNELS; URINARY BLADDER; URINARY INCONTINENCE, URGE; URINATION; URODYNAMICS;

EID: 84941807845     PISSN: 03022838     EISSN: 18737560     Source Type: Journal    
DOI: 10.1016/j.eururo.2015.03.037     Document Type: Article

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