Direct regulation of E-cadherin by targeted histone methylation of TALE-SET fusion protein in cancer cells

Oncotarget

Volumn 6, Issue 27, 2015, Pages 23837-23844

  Cho, Hyun Soo ^a   Kang, Jeong Gu ^a   Lee, Jae Hye ^a,b   Lee, Jeong Ju ^a   Jeon, Seong Kook ^a   Ko, Jeong Heon ^a   Kim, Dae Soo ^a   Park, Kun Hyang ^a   Kim, Yong Sam ^a   Kim, Nam Soon ^a,b  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b University of Science and Technology (UST)   (South Korea)

Author keywords

Cancer; Histone methylation; Migration; TALEN

Indexed keywords

HYBRID PROTEIN; TALE SET PROTEIN; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; UNCLASSIFIED DRUG; UVOMORULIN; CADHERIN; CHAPERONE; DNA BINDING PROTEIN; HISTONE; HOMEODOMAIN PROTEIN; REPRESSOR PROTEIN; SET PROTEIN, HUMAN; TGIF1 PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ARTICLE; BINDING SITE; CANCER CELL; CELL INVASION; CELL MIGRATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENZYME INHIBITION; EPIGENETICS; EPITHELIAL MESENCHYMAL TRANSITION; HISTONE METHYLATION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MODIFICATION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION; CELL MOTION; DNA METHYLATION; GENETICS; HCT 116 CELL LINE; HELA CELL LINE; METABOLISM; NEOPLASM; PROTEIN TERTIARY STRUCTURE; TUMOR CELL LINE; TUMOR INVASION; WOUND HEALING;

BINDING SITES; CADHERINS; CELL LINE, TUMOR; CELL MOVEMENT; DNA METHYLATION; DNA-BINDING PROTEINS; EPITHELIAL-MESENCHYMAL TRANSITION; HCT116 CELLS; HELA CELLS; HISTONE CHAPERONES; HISTONES; HOMEODOMAIN PROTEINS; HUMANS; NEOPLASM INVASIVENESS; NEOPLASMS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; REPRESSOR PROTEINS; TRANSCRIPTION FACTORS; WOUND HEALING;

EID: 84941793540     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.4340     Document Type: Article

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