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Volumn 4, Issue 11, 2015, Pages

An optimized peptide vaccine strategy capable of inducing multivalent CD8+ T cell responses with potent antitumor effects

Author keywords

cancer vaccine; dendritic cells; heterologous prime boost vaccination; multivalent CD8+ T cells; peptide based vaccine; tumor immunity

Indexed keywords

CANCER VACCINE; CD40 LIGAND MONOCLONAL ANTIBODY; DIPHTHERIA PERTUSSIS TETANUS VACCINE; GAMMA INTERFERON; PEPTIDE VACCINE; POLYINOSINIC POLYCYTIDYLIC ACID;

EID: 84941774508     PISSN: 21624011     EISSN: 2162402X     Source Type: Journal    
DOI: 10.1080/2162402X.2015.1043504     Document Type: Article
Times cited : (27)

References (41)
  • 1
    • 67650744372 scopus 로고    scopus 로고
    • Immune therapy for cancer
    • 19007331
    • M.Dougan, G.Dranoff. Immune therapy for cancer. Annu Rev Immunol 2009; 27:83-117; PMID:19007331; http://dx.doi.org/10.1146/annurev.immunol.021908.132544
    • (2009) Annu Rev Immunol , vol.27 , pp. 83-117
    • Dougan, M.1    Dranoff, G.2
  • 3
    • 0026235070 scopus 로고
    • Cytotoxic T lymphocyte therapy of cancer and tumor escape mechanisms
    • 1773050
    • C.J.Melief, W.M.Kast. Cytotoxic T lymphocyte therapy of cancer and tumor escape mechanisms. Semin Cancer Biol 1991; 2:347-54; PMID:1773050
    • (1991) Semin Cancer Biol , vol.2 , pp. 347-354
    • Melief, C.J.1    Kast, W.M.2
  • 4
    • 84876861350 scopus 로고    scopus 로고
    • Plasticity of tumour and immune cells: a source of heterogeneity and a cause for therapy resistance?
    • 23535846
    • M.Holzel, A.Bovier, T.Tuting. Plasticity of tumour and immune cells: a source of heterogeneity and a cause for therapy resistance? Nat Rev Cancer 2013; 13:365-76; PMID:23535846; http://dx.doi.org/10.1038/nrc3498
    • (2013) Nat Rev Cancer , vol.13 , pp. 365-376
    • Holzel, M.1    Bovier, A.2    Tuting, T.3
  • 5
    • 0027157303 scopus 로고
    • Dendritic cells: antigen presentation, accessory function and clinical relevance
    • 8379358
    • R.M.Steinman, M.Witmer-Pack, K.Inaba. Dendritic cells: antigen presentation, accessory function and clinical relevance. Adv Exp Med Biol 1993; 329:1-9; PMID:8379358; http://dx.doi.org/10.1007/978-1-4615-2930-9_1
    • (1993) Adv Exp Med Biol , vol.329 , pp. 1-9
    • Steinman, R.M.1    Witmer-Pack, M.2    Inaba, K.3
  • 6
    • 84892171528 scopus 로고    scopus 로고
    • Clinical implications of co-inhibitory molecule expression in the tumor microenvironment for DC vaccination: a game of stop and go
    • 24348481
    • A.Vasaturo, S.Di Blasio, D.G.Peeters, C.C.de Koning, J.M.de Vries, C.G.Figdor, S.V.Hato. Clinical implications of co-inhibitory molecule expression in the tumor microenvironment for DC vaccination: a game of stop and go. Front Immunol 2013; 4:417; PMID:24348481; http://dx.doi.org/10.3389/fimmu.2013.00417
    • (2013) Front Immunol , vol.4 , pp. 417
    • Vasaturo, A.1    Di Blasio, S.2    Peeters, D.G.3    de Koning, C.C.4    de Vries, J.M.5    Figdor, C.G.6    Hato, S.V.7
  • 7
    • 84859717471 scopus 로고    scopus 로고
    • Dendritic cells the tumor microenvironment and the challenges for an effective antitumor vaccination
    • 22505809
    • F.Benencia, L.Sprague, J.McGinty, M.Pate, M.Muccioli. Dendritic cells the tumor microenvironment and the challenges for an effective antitumor vaccination. J Biomed Biotechnol 2012; 2012:425476; PMID:22505809; http://dx.doi.org/10.1155/2012/425476
    • (2012) J Biomed Biotechnol , vol.2012 , pp. 425476
    • Benencia, F.1    Sprague, L.2    McGinty, J.3    Pate, M.4    Muccioli, M.5
  • 8
    • 71549172516 scopus 로고    scopus 로고
    • Optimized peptide vaccines eliciting extensive CD8 T-cell responses with therapeutic antitumor effects
    • 19903852
    • H.I.Cho, E.Celis. Optimized peptide vaccines eliciting extensive CD8 T-cell responses with therapeutic antitumor effects. Cancer Res 2009; 69:9012-9; PMID:19903852; http://dx.doi.org/10.1158/0008-5472.CAN-09-2019
    • (2009) Cancer Res , vol.69 , pp. 9012-9019
    • Cho, H.I.1    Celis, E.2
  • 9
    • 57149086082 scopus 로고    scopus 로고
    • In vivo expansion, persistence, and function of peptide vaccine-induced CD8 T cells occur independently of CD4 T cells
    • 19047170
    • D.Assudani, H.I.Cho, N.DeVito, N.Bradley, E.Celis. In vivo expansion, persistence, and function of peptide vaccine-induced CD8 T cells occur independently of CD4 T cells. Cancer Res 2008; 68:9892-9; PMID:19047170; http://dx.doi.org/10.1158/0008-5472.CAN-08-3134
    • (2008) Cancer Res , vol.68 , pp. 9892-9899
    • Assudani, D.1    Cho, H.I.2    DeVito, N.3    Bradley, N.4    Celis, E.5
  • 10
    • 84860191757 scopus 로고    scopus 로고
    • A potent vaccination strategy that circumvents lymphodepletion for effective antitumor adoptive T-cell therapy
    • 22367213
    • H.I.Cho, E.Reyes-Vargas, J.C.Delgado, E.Celis. A potent vaccination strategy that circumvents lymphodepletion for effective antitumor adoptive T-cell therapy. Cancer Res 2012; 72:1986-95; PMID:22367213; http://dx.doi.org/10.1158/0008-5472.CAN-11-3246
    • (2012) Cancer Res , vol.72 , pp. 1986-1995
    • Cho, H.I.1    Reyes-Vargas, E.2    Delgado, J.C.3    Celis, E.4
  • 11
    • 84877825063 scopus 로고    scopus 로고
    • BiVax: a peptide/poly-IC subunit vaccine that mimics an acute infection elicits vast and effective anti-tumor CD8 T-cell responses
    • 23266830
    • H.I.Cho, K.Barrios, Y.R.Lee, A.K.Linowski, E.Celis. BiVax: a peptide/poly-IC subunit vaccine that mimics an acute infection elicits vast and effective anti-tumor CD8 T-cell responses. Cancer Immunol Immunother 2013; 62:787-99; PMID:23266830; http://dx.doi.org/10.1007/s00262-012-1382-6
    • (2013) Cancer Immunol Immunother , vol.62 , pp. 787-799
    • Cho, H.I.1    Barrios, K.2    Lee, Y.R.3    Linowski, A.K.4    Celis, E.5
  • 13
    • 0037884716 scopus 로고    scopus 로고
    • A single heteroclitic epitope determines cancer immunity after xenogeneic DNA immunization against a tumor differentiation antigen
    • 12734366
    • J.S.Gold, C.R.Ferrone, J.A.Guevara-Patino, W.G.Hawkins, R.Dyall, M.E.Engelhorn, J.D.Wolchok, J.J.Lewis, A.N.Houghton. A single heteroclitic epitope determines cancer immunity after xenogeneic DNA immunization against a tumor differentiation antigen. J Immunol 2003; 170:5188-94; PMID:12734366; http://dx.doi.org/10.4049/jimmunol.170.10.5188
    • (2003) J Immunol , vol.170 , pp. 5188-5194
    • Gold, J.S.1    Ferrone, C.R.2    Guevara-Patino, J.A.3    Hawkins, W.G.4    Dyall, R.5    Engelhorn, M.E.6    Wolchok, J.D.7    Lewis, J.J.8    Houghton, A.N.9
  • 15
    • 4444253689 scopus 로고    scopus 로고
    • + T cell contraction is controlled by early inflammation
    • 15247915
    • + T cell contraction is controlled by early inflammation. Nat Immunol 2004; 5:809-17; PMID:15247915; http://dx.doi.org/10.1038/ni1098
    • (2004) Nat Immunol , vol.5 , pp. 809-817
    • Badovinac, V.P.1    Porter, B.B.2    Harty, J.T.3
  • 16
    • 34548027168 scopus 로고    scopus 로고
    • Generation of CD8 T cell memory is regulated by IL-12
    • 17675465
    • E.L.Pearce, H.Shen. Generation of CD8 T cell memory is regulated by IL-12. J Immunol 2007; 179:2074-81; PMID:17675465; http://dx.doi.org/10.4049/jimmunol.179.4.2074
    • (2007) J Immunol , vol.179 , pp. 2074-2081
    • Pearce, E.L.1    Shen, H.2
  • 17
    • 34250890040 scopus 로고    scopus 로고
    • + T cell generation after acute infection
    • 17579021
    • + T cell generation after acute infection. J Immunol 2007; 179:53-63; PMID:17579021; http://dx.doi.org/10.4049/jimmunol.179.1.53
    • (2007) J Immunol , vol.179 , pp. 53-63
    • Badovinac, V.P.1    Harty, J.T.2
  • 19
    • 84892144534 scopus 로고    scopus 로고
    • Dendritic cells in cancer immunotherapy clinical trials: are we making progress?
    • 24379816
    • L.H.Butterfield. Dendritic cells in cancer immunotherapy clinical trials: are we making progress? Front Immunol 2013; 4:454; PMID:24379816; http://dx.doi.org/10.3389/fimmu.2013.00454
    • (2013) Front Immunol , vol.4 , pp. 454
    • Butterfield, L.H.1
  • 20
    • 0141993954 scopus 로고    scopus 로고
    • Route of immunization with peptide-pulsed dendritic cells controls the distribution of memory and effector T cells in lymphoid tissues and determines the pattern of regional tumor control
    • 14530375
    • D.W.Mullins, S.L.Sheasley, R.M.Ream, T.N.Bullock, Y.X.Fu, V.H.Engelhard. Route of immunization with peptide-pulsed dendritic cells controls the distribution of memory and effector T cells in lymphoid tissues and determines the pattern of regional tumor control. J Exp Med 2003; 198:1023-34; PMID:14530375; http://dx.doi.org/10.1084/jem.20021348
    • (2003) J Exp Med , vol.198 , pp. 1023-1034
    • Mullins, D.W.1    Sheasley, S.L.2    Ream, R.M.3    Bullock, T.N.4    Fu, Y.X.5    Engelhard, V.H.6
  • 21
    • 0034176364 scopus 로고    scopus 로고
    • The prime-boost strategy: exciting prospects for improved vaccination
    • 10740236
    • I.A.Ramshaw, A.J.Ramsay. The prime-boost strategy: exciting prospects for improved vaccination. Immunol Today 2000; 21:163-5; PMID:10740236; http://dx.doi.org/10.1016/S0167-5699(00)01612-1
    • (2000) Immunol Today , vol.21 , pp. 163-165
    • Ramshaw, I.A.1    Ramsay, A.J.2
  • 22
    • 33645889340 scopus 로고    scopus 로고
    • Enhanced immunogenicity and antitumour effects with heterologous prime-boost regime using vaccines based on MG7-Ag mimotope of gastric cancer
    • 16634806
    • T.Lin, S.Liang, F.Meng, Q.Han, C.Guo, L.Sun, Y.Chen, Z.Liu, Z.Yu, H.Xie et al. Enhanced immunogenicity and antitumour effects with heterologous prime-boost regime using vaccines based on MG7-Ag mimotope of gastric cancer. Clin Exp Immunol 2006; 144:319-25; PMID:16634806; http://dx.doi.org/10.1111/j.1365-2249.2006.03065.x
    • (2006) Clin Exp Immunol , vol.144 , pp. 319-325
    • Lin, T.1    Liang, S.2    Meng, F.3    Han, Q.4    Guo, C.5    Sun, L.6    Chen, Y.7    Liu, Z.8    Yu, Z.9    Xie, H.10
  • 23
    • 33847075902 scopus 로고    scopus 로고
    • In vivo effects of vaccination with six-transmembrane epithelial antigen of the prostate: a candidate antigen for treating prostate cancer
    • 17283172
    • L.Garcia-Hernandez Mde, A.Gray, B.Hubby, W.M.Kast. In vivo effects of vaccination with six-transmembrane epithelial antigen of the prostate: a candidate antigen for treating prostate cancer. Cancer Res 2007; 67:1344-51; PMID:17283172; http://dx.doi.org/10.1158/0008-5472.CAN-06-2996
    • (2007) Cancer Res , vol.67 , pp. 1344-1351
    • Garcia-Hernandez Mde, L.1    Gray, A.2    Hubby, B.3    Kast, W.M.4
  • 24
    • 0842324614 scopus 로고    scopus 로고
    • Jump-starting the immune system: prime-boosting comes of age
    • 15102369
    • D.L.Woodland. Jump-starting the immune system: prime-boosting comes of age. Trends Immunol 2004; 25:98-104; PMID:15102369; http://dx.doi.org/10.1016/j.it.2003.11.009
    • (2004) Trends Immunol , vol.25 , pp. 98-104
    • Woodland, D.L.1
  • 25
    • 0036157469 scopus 로고    scopus 로고
    • Prime-boost immunization generates a high frequency, high-avidity CD8(+) cytotoxic T lymphocyte population
    • 11751749
    • M.J.Estcourt, A.J.Ramsay, A.Brooks, S.A.Thomson, C.J.Medveckzy, I.A.Ramshaw. Prime-boost immunization generates a high frequency, high-avidity CD8(+) cytotoxic T lymphocyte population. Int Immunol 2002; 14:31-7; PMID:11751749; http://dx.doi.org/10.1093/intimm/14.1.31
    • (2002) Int Immunol , vol.14 , pp. 31-37
    • Estcourt, M.J.1    Ramsay, A.J.2    Brooks, A.3    Thomson, S.A.4    Medveckzy, C.J.5    Ramshaw, I.A.6
  • 26
    • 0036085692 scopus 로고    scopus 로고
    • Prime-boost immunization strategies for infectious diseases
    • 11883691
    • H.McShane. Prime-boost immunization strategies for infectious diseases. Curr Opin Mol Ther 2002; 4:23-7; PMID:11883691
    • (2002) Curr Opin Mol Ther , vol.4 , pp. 23-27
    • McShane, H.1
  • 27
    • 0032482356 scopus 로고    scopus 로고
    • Help for cytotoxic-T-cell responses is mediated by CD40 signalling
    • 9624004
    • S.R.Bennett, F.R.Carbone, F.Karamalis, R.A.Flavell, J.F.Miller, W.R.Heath. Help for cytotoxic-T-cell responses is mediated by CD40 signalling. Nature 1998; 393:478-80; PMID:9624004; http://dx.doi.org/10.1038/30996
    • (1998) Nature , vol.393 , pp. 478-480
    • Bennett, S.R.1    Carbone, F.R.2    Karamalis, F.3    Flavell, R.A.4    Miller, J.F.5    Heath, W.R.6
  • 28
    • 34249722182 scopus 로고    scopus 로고
    • Eradication of lymphoma by CD8 T cells following anti-CD40 monoclonal antibody therapy is critically dependent on CD27 costimulation
    • 17311995
    • R.R.French, V.Y.Taraban, G.R.Crowther, T.F.Rowley, J.C.Gray, P.W.Johnson, A.L.Tutt, A.Al-Shamkhani, M.J.Glennie. Eradication of lymphoma by CD8 T cells following anti-CD40 monoclonal antibody therapy is critically dependent on CD27 costimulation. Blood 2007; 109:4810-5; PMID:17311995; http://dx.doi.org/10.1182/blood-2006-11-057216
    • (2007) Blood , vol.109 , pp. 4810-4815
    • French, R.R.1    Taraban, V.Y.2    Crowther, G.R.3    Rowley, T.F.4    Gray, J.C.5    Johnson, P.W.6    Tutt, A.L.7    Al-Shamkhani, A.8    Glennie, M.J.9
  • 29
    • 33847388793 scopus 로고    scopus 로고
    • + T cell help
    • 17312128
    • + T cell help. J Immunol 2007; 178:2844-52; PMID:17312128; http://dx.doi.org/10.4049/jimmunol.178.5.2844
    • (2007) J Immunol , vol.178 , pp. 2844-2852
    • Hernandez, M.G.1    Shen, L.2    Rock, K.L.3
  • 30
    • 84892463487 scopus 로고    scopus 로고
    • + T-cell expansion upon vaccinia virus challenge relies on CD40 signaling
    • 24108445
    • + T-cell expansion upon vaccinia virus challenge relies on CD40 signaling. Eur J Immunol 2014; 44:115-26; PMID:24108445; http://dx.doi.org/10.1002/eji.201343805
    • (2014) Eur J Immunol , vol.44 , pp. 115-126
    • Bedenikovic, G.1    Crouse, J.2    Oxenius, A.3
  • 32
    • 66149140993 scopus 로고    scopus 로고
    • Depletion of CD4 T cells enhances immunotherapy for neuroblastoma after syngeneic HSCT but compromises development of antitumor immune memory
    • 19182203
    • W.Jing, J.A.Gershan, B.D.Johnson. Depletion of CD4 T cells enhances immunotherapy for neuroblastoma after syngeneic HSCT but compromises development of antitumor immune memory. Blood 2009; 113:4449-57; PMID:19182203; http://dx.doi.org/10.1182/blood-2008-11-190827
    • (2009) Blood , vol.113 , pp. 4449-4457
    • Jing, W.1    Gershan, J.A.2    Johnson, B.D.3
  • 33
    • 78649557780 scopus 로고    scopus 로고
    • Efficient Treg depletion induces T-cell infiltration and rejection of large tumors
    • 21072887
    • X.Li, E.Kostareli, J.Suffner, N.Garbi, G.J.Hammerling. Efficient Treg depletion induces T-cell infiltration and rejection of large tumors. Eur J Immunol 2010; 40:3325-35; PMID:21072887; http://dx.doi.org/10.1002/eji.201041093
    • (2010) Eur J Immunol , vol.40 , pp. 3325-3335
    • Li, X.1    Kostareli, E.2    Suffner, J.3    Garbi, N.4    Hammerling, G.J.5
  • 34
    • 78049276260 scopus 로고    scopus 로고
    • Selective depletion of Foxp3+ regulatory T cells improves effective therapeutic vaccination against established melanoma
    • 20924102
    • K.Klages, C.T.Mayer, K.Lahl, C.Loddenkemper, M.W.Teng, S.F.Ngiow, M.J.Smyth, A.Hamann, J.Huehn, T.Sparwasser. Selective depletion of Foxp3+ regulatory T cells improves effective therapeutic vaccination against established melanoma. Cancer Res 2010; 70:7788-99; PMID:20924102; http://dx.doi.org/10.1158/0008-5472.CAN-10-1736
    • (2010) Cancer Res , vol.70 , pp. 7788-7799
    • Klages, K.1    Mayer, C.T.2    Lahl, K.3    Loddenkemper, C.4    Teng, M.W.5    Ngiow, S.F.6    Smyth, M.J.7    Hamann, A.8    Huehn, J.9    Sparwasser, T.10
  • 35
    • 41149178490 scopus 로고    scopus 로고
    • Comparative methodologies of regulatory T cell depletion in a murine melanoma model
    • 18295790
    • N.Matsushita, S.A.Pilon-Thomas, L.M.Martin, A.I.Riker. Comparative methodologies of regulatory T cell depletion in a murine melanoma model. J Immunol Methods 2008; 333:167-79; PMID:18295790; http://dx.doi.org/10.1016/j.jim.2008.01.012
    • (2008) J Immunol Methods , vol.333 , pp. 167-179
    • Matsushita, N.1    Pilon-Thomas, S.A.2    Martin, L.M.3    Riker, A.I.4
  • 36
    • 33645465526 scopus 로고    scopus 로고
    • Selective stimulation of T cell subsets with antibody-cytokine immune complexes
    • 16484453
    • O.Boyman, M.Kovar, M.P.Rubinstein, C.D.Surh, J.Sprent. Selective stimulation of T cell subsets with antibody-cytokine immune complexes. Science 2006; 311:1924-7; PMID:16484453; http://dx.doi.org/10.1126/science.1122927
    • (2006) Science , vol.311 , pp. 1924-1927
    • Boyman, O.1    Kovar, M.2    Rubinstein, M.P.3    Surh, C.D.4    Sprent, J.5
  • 37
    • 84857646605 scopus 로고    scopus 로고
    • The role of interleukin-2 during homeostasis and activation of the immune system
    • 22343569
    • O.Boyman, J.Sprent. The role of interleukin-2 during homeostasis and activation of the immune system. Nat Rev Immunol 2012; 12:180-90; PMID:22343569; http://dx.doi.org/10.1038/nri3156′
    • (2012) Nat Rev Immunol , vol.12 , pp. 180-190
    • Boyman, O.1    Sprent, J.2
  • 38
    • 41149112957 scopus 로고    scopus 로고
    • Enhancing therapeutic vaccination by blocking PD-1-mediated inhibitory signals during chronic infection
    • 18332181
    • S.J.Ha, S.N.Mueller, E.J.Wherry, D.L.Barber, R.D.Aubert, A.H.Sharpe, G.J.Freeman, R.Ahmed. Enhancing therapeutic vaccination by blocking PD-1-mediated inhibitory signals during chronic infection. J Exp Med 2008; 205:543-55; PMID:18332181; http://dx.doi.org/10.1084/jem.20071949
    • (2008) J Exp Med , vol.205 , pp. 543-555
    • Ha, S.J.1    Mueller, S.N.2    Wherry, E.J.3    Barber, D.L.4    Aubert, R.D.5    Sharpe, A.H.6    Freeman, G.J.7    Ahmed, R.8
  • 39
    • 84859158384 scopus 로고    scopus 로고
    • Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity
    • 22236695
    • S.L.Topalian, C.G.Drake, D.M.Pardoll. Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity. Curr Opin Immunol 2012; 24:207-12; PMID:22236695; http://dx.doi.org/10.1016/j.coi.2011.12.009
    • (2012) Curr Opin Immunol , vol.24 , pp. 207-212
    • Topalian, S.L.1    Drake, C.G.2    Pardoll, D.M.3
  • 40
    • 84883863501 scopus 로고    scopus 로고
    • Up-regulation of PD-L1, IDO, and T(regs) in the melanoma tumor microenvironment is driven by CD8(+) T cells
    • 23986400
    • S.Spranger, R.M.Spaapen, Y.Zha, J.Williams, Y.Meng, T.T.Ha, T.F.Gajewski. Up-regulation of PD-L1, IDO, and T(regs) in the melanoma tumor microenvironment is driven by CD8(+) T cells. Sci Transl Med 2013; 5:200ra116; PMID:23986400; http://dx.doi.org/10.1126/scitranslmed.3006504
    • (2013) Sci Transl Med , vol.5 , pp. 116-200
    • Spranger, S.1    Spaapen, R.M.2    Zha, Y.3    Williams, J.4    Meng, Y.5    Ha, T.T.6    Gajewski, T.F.7


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