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Volumn 13, Issue 9, 2015, Pages 1066-1070

Prolonged response to trastuzumab in a patient with HER2-nonamplified breast cancer with elevated HER2 dimerization harboring an ERBB2 S310F mutation

Author keywords

[No Author keywords available]

Indexed keywords

BEVACIZUMAB; CAPECITABINE; CARBOPLATIN; CYCLOPHOSPHAMIDE; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN; EVEROLIMUS; FLUOROURACIL; FULVESTRANT; GEMCITABINE; METHOTREXATE; NAVELBINE; PACLITAXEL; PERTUZUMAB; PROGESTERONE RECEPTOR; TAMOXIFEN; TRASTUZUMAB; ANTINEOPLASTIC AGENT; ERBB2 PROTEIN, HUMAN; ESTRADIOL; MONOCLONAL ANTIBODY; PROTEIN KINASE INHIBITOR;

EID: 84941770307     PISSN: 15401405     EISSN: 15401413     Source Type: Journal    
DOI: 10.6004/jnccn.2015.0132     Document Type: Article
Times cited : (31)

References (28)
  • 2
    • 73149115341 scopus 로고    scopus 로고
    • Lapatinib combined with letrozole versus letrozole and placebo as first-line therapy for postmenopausal hormone receptor-positive metastatic breast cancer
    • Johnston S, Pippen J Jr, Pivot X, et al. Lapatinib combined with letrozole versus letrozole and placebo as first-line therapy for postmenopausal hormone receptor-positive metastatic breast cancer. J Clin Oncol 2009;27:5538-5546.
    • (2009) J Clin Oncol , vol.27 , pp. 5538-5546
    • Johnston, S.1    Pippen, J.2    Pivot, X.3
  • 3
    • 62449323761 scopus 로고    scopus 로고
    • A novel proximity assay for the detection of proteins and protein complexes: Quantitation of HER1 and HER2 total protein expression and homodimerization in formalin-fixed, paraffin-embedded cell lines and breast cancer tissue
    • Shi Y, Huang W, Tan Y, et al. A novel proximity assay for the detection of proteins and protein complexes: quantitation of HER1 and HER2 total protein expression and homodimerization in formalin-fixed, paraffin-embedded cell lines and breast cancer tissue. Diagn Mol Pathol 2009;18:11-21.
    • (2009) Diagn Mol Pathol , vol.18 , pp. 11-21
    • Shi, Y.1    Huang, W.2    Tan, Y.3
  • 4
    • 77955763771 scopus 로고    scopus 로고
    • Analytical validation of a highly quantitative, sensitive, accurate, and reproducible assay (HERmark) for the measurement of HER2 total protein and HER2 homodimers in FFPE breast cancer tumor specimens
    • Larson JS, Goodman LJ, Tan Y, et al. Analytical validation of a highly quantitative, sensitive, accurate, and reproducible assay (HERmark) for the measurement of HER2 total protein and HER2 homodimers in FFPE breast cancer tumor specimens. Patholog Res Int 2010;2010:814176.
    • (2010) Patholog Res Int , vol.2010 , pp. 814176
    • Larson, J.S.1    Goodman, L.J.2    Tan, Y.3
  • 5
    • 77955597966 scopus 로고    scopus 로고
    • Comparison of central HER2 testing with quantitative total HER2 expression and HER2 homodimer measurements using a novel proximity-based assay
    • Huang W, Reinholz M, Weidler J, et al. Comparison of central HER2 testing with quantitative total HER2 expression and HER2 homodimer measurements using a novel proximity-based assay. Am J Clin Pathol 2010;134:303-311.
    • (2010) Am J Clin Pathol , vol.134 , pp. 303-311
    • Huang, W.1    Reinholz, M.2    Weidler, J.3
  • 6
    • 78449281431 scopus 로고    scopus 로고
    • Quantitative HER2 protein levels predict outcome in fluorescence in situ hybridization-positive patients with metastatic breast cancer treated with trastuzumab
    • Lipton A, Kostler WJ, Leitzel K, et al. Quantitative HER2 protein levels predict outcome in fluorescence in situ hybridization-positive patients with metastatic breast cancer treated with trastuzumab. Cancer 2010;116:5168-5178.
    • (2010) Cancer , vol.116 , pp. 5168-5178
    • Lipton, A.1    Kostler, W.J.2    Leitzel, K.3
  • 7
    • 0029814271 scopus 로고    scopus 로고
    • A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor
    • Tzahar E, Waterman H, Chen X, et al. A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor. Mol Cell Biol 1996;16:5276-5287.
    • (1996) Mol Cell Biol , vol.16 , pp. 5276-5287
    • Tzahar, E.1    Waterman, H.2    Chen, X.3
  • 8
    • 2142843806 scopus 로고    scopus 로고
    • Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions
    • Pinkas-Kramarski R, Soussan L, Waterman H, et al. Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions. EMBO J 1996;15:2452-2467.
    • (1996) EMBO J , vol.15 , pp. 2452-2467
    • Pinkas-Kramarski, R.1    Soussan, L.2    Waterman, H.3
  • 9
    • 0034115478 scopus 로고    scopus 로고
    • Blocking HER-2/HER-3 function with a dominant negative form of HER-3 in cells stimulated by heregulin and in breast cancer cells with HER-2 gene amplification
    • Ram TG, Schelling ME, Hosick HL. Blocking HER-2/HER-3 function with a dominant negative form of HER-3 in cells stimulated by heregulin and in breast cancer cells with HER-2 gene amplification. Cell Growth Differ 2000;11:173-183.
    • (2000) Cell Growth Differ , vol.11 , pp. 173-183
    • Ram, T.G.1    Schelling, M.E.2    Hosick, H.L.3
  • 10
    • 0042307325 scopus 로고    scopus 로고
    • The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation
    • Holbro T, Beerli RR, Maurer F, et al. The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation. Proc Natl Acad Sci U S A 2003;100:8933-8938.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 8933-8938
    • Holbro, T.1    Beerli, R.R.2    Maurer, F.3
  • 11
    • 48649092620 scopus 로고    scopus 로고
    • A central role for HER3 in HER2-amplified breast cancer: Implications for targeted therapy
    • Lee-Hoeflich S T, Crocker L, Yao E, et al. A central role for HER3 in HER2-amplified breast cancer: implications for targeted therapy. Cancer Res 2008;68:5878-5887.
    • (2008) Cancer Res , vol.68 , pp. 5878-5887
    • Lee-Hoeflich, S.T.1    Crocker, L.2    Yao, E.3
  • 12
    • 84884279586 scopus 로고    scopus 로고
    • HER3, p95HER2, and HER2 protein expression levels define multiple subtypes of HER2-positive metastatic breast cancer
    • Lipton A, Goodman L, Leitzel K, et al. HER3, p95HER2, and HER2 protein expression levels define multiple subtypes of HER2-positive metastatic breast cancer. Breast Cancer Res Treat 2013;141:43-53.
    • (2013) Breast Cancer Res Treat , vol.141 , pp. 43-53
    • Lipton, A.1    Goodman, L.2    Leitzel, K.3
  • 13
    • 79551527609 scopus 로고    scopus 로고
    • Profiling the HER3/PI3K pathway in breast tumors using proximity-directed assays identifies correlations between protein complexes and phosphoproteins
    • Mukherjee A, Badal Y, Nguyen XT, et al. Profiling the HER3/PI3K pathway in breast tumors using proximity-directed assays identifies correlations between protein complexes and phosphoproteins. PLoS One 2011;6:e16443.
    • (2011) PLoS One , vol.6 , pp. e16443
    • Mukherjee, A.1    Badal, Y.2    Nguyen, X.T.3
  • 14
    • 84941778726 scopus 로고    scopus 로고
    • Profiling HER3/ErbB3 activation in formalin-fixed, paraffin-embedded (FFPE) breast tumor samples that expresss high and low HER2/ErbB2 levels using proximitybased immunoassays. [abstract]
    • 3029
    • Wallweber J, Chenna A, Ravanera R, et al. Profiling HER3/ErbB3 activation in formalin-fixed, paraffin-embedded (FFPE) breast tumor samples that expresss high and low HER2/ErbB2 levels using proximitybased immunoassays. [abstract]. Cancer Res 2013;73:Abstract 3029.
    • (2013) Cancer Res , vol.73
    • Wallweber, J.1    Chenna, A.2    Ravanera, R.3
  • 15
    • 1842605531 scopus 로고    scopus 로고
    • Insights into ERBB signaling from the structure of the ERBB2-pertuzumab complex
    • Franklin MC, Carey KD, Vajdos F F, et al. Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex. Cancer Cell 2004;5:317-328.
    • (2004) Cancer Cell , vol.5 , pp. 317-328
    • Franklin, M.C.1    Carey, K.D.2    Vajdos, F.F.3
  • 16
    • 84861576201 scopus 로고    scopus 로고
    • The landscape of cancer genes and mutational processes in breast cancer
    • Stephens PJ, Tarpey PS, Davies H, et al. The landscape of cancer genes and mutational processes in breast cancer. Nature 2012;486:400-404.
    • (2012) Nature , vol.486 , pp. 400-404
    • Stephens, P.J.1    Tarpey, P.S.2    Davies, H.3
  • 17
    • 84862526929 scopus 로고    scopus 로고
    • The clonal and mutational evolution spectrum of primary triple-negative breast cancers
    • Shah SP, Roth A, Goya R, et al. The clonal and mutational evolution spectrum of primary triple-negative breast cancers. Nature 2012;486:395-399.
    • (2012) Nature , vol.486 , pp. 395-399
    • Shah, S.P.1    Roth, A.2    Goya, R.3
  • 18
    • 77955660663 scopus 로고    scopus 로고
    • Diverse somatic mutation patterns and pathway alterations in human cancers
    • Kan Z, Jaiswal BS, Stinson J, et al. Diverse somatic mutation patterns and pathway alterations in human cancers. Nature 2010;466:869-873.
    • (2010) Nature , vol.466 , pp. 869-873
    • Kan, Z.1    Jaiswal, B.S.2    Stinson, J.3
  • 19
    • 84862584058 scopus 로고    scopus 로고
    • Whole-genome analysis informs breast cancer response to aromatase inhibition
    • Ellis MJ, Ding L, Shen D, et al. Whole-genome analysis informs breast cancer response to aromatase inhibition. Nature 2012;486:353-360.
    • (2012) Nature , vol.486 , pp. 353-360
    • Ellis, M.J.1    Ding, L.2    Shen, D.3
  • 20
    • 84877028141 scopus 로고    scopus 로고
    • Comprehensive molecular portraits of human breast tumours
    • Cancer Genome Atlas Research Network. Comprehensive molecular portraits of human breast tumours. Nature 2012;490:61-70.
    • (2012) Nature , vol.490 , pp. 61-70
    • Cancer Genome Atlas Research Network1
  • 21
    • 31544449750 scopus 로고    scopus 로고
    • Somatic mutations of ERBB2 kinase domain in gastric, colorectal, and breast carcinomas
    • Lee JW, Soung YH, Seo SH, et al. Somatic mutations of ERBB2 kinase domain in gastric, colorectal, and breast carcinomas. Clin Cancer Res 2006;12:57-61.
    • (2006) Clin Cancer Res , vol.12 , pp. 57-61
    • Lee, J.W.1    Soung, Y.H.2    Seo, S.H.3
  • 22
    • 70349969478 scopus 로고    scopus 로고
    • Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution
    • Shah S P, Morin RD, Khattra J, et al. Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution. Nature 2009;461:809-813.
    • (2009) Nature , vol.461 , pp. 809-813
    • Shah, S.P.1    Morin, R.D.2    Khattra, J.3
  • 23
    • 84862523863 scopus 로고    scopus 로고
    • Sequence analysis of mutations and translocations across breast cancer subtypes
    • Banerji S, Cibulskis K, Rangel-Escareno C, et al. Sequence analysis of mutations and translocations across breast cancer subtypes. Nature 2012;486:405-409.
    • (2012) Nature , vol.486 , pp. 405-409
    • Banerji, S.1    Cibulskis, K.2    Rangel-Escareno, C.3
  • 24
    • 84873918443 scopus 로고    scopus 로고
    • Activating HER2 mutations in HER2 gene amplification negative breast cancer
    • Bose R, Kavuri SM, Searleman AC, et al. Activating HER2 mutations in HER2 gene amplification negative breast cancer. Cancer Discov 2013;3:224-237.
    • (2013) Cancer Discov , vol.3 , pp. 224-237
    • Bose, R.1    Kavuri, S.M.2    Searleman, A.C.3
  • 25
    • 80055032877 scopus 로고    scopus 로고
    • Differential sensitivity of ERBB2 kinase domain mutations towards lapatinib
    • Kancha RK, von Bubnoff N, Bartosch N, et al. Differential sensitivity of ERBB2 kinase domain mutations towards lapatinib. PLoS One 2011;6:e26760.
    • (2011) PLoS One , vol.6 , pp. e26760
    • Kancha, R.K.1    Von Bubnoff, N.2    Bartosch, N.3
  • 26
    • 84865994665 scopus 로고    scopus 로고
    • Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2
    • Greulich H, Kaplan B, Mertins P, et al. Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2. Proc Natl Acad Sci U S A 2012;109:14476-14481.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 14476-14481
    • Greulich, H.1    Kaplan, B.2    Mertins, P.3
  • 27
    • 79959838081 scopus 로고    scopus 로고
    • Integrated genomic analyses of ovarian carcinoma
    • Cancer Genome Atlas Research Network. Integrated genomic analyses of ovarian carcinoma. Nature 2011;474:609-615.
    • (2011) Nature , vol.474 , pp. 609-615
    • Cancer Genome Atlas Research Network1
  • 28
    • 84859169877 scopus 로고    scopus 로고
    • The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
    • Barretina J, Caponigro G, Stransky N, et al. The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature 2012;483:603-607.
    • (2012) Nature , vol.483 , pp. 603-607
    • Barretina, J.1    Caponigro, G.2    Stransky, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.