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Volumn 59, Issue 11, 2015, Pages 2199-2208

Aspalathin improves glucose and lipid metabolism in 3T3-L1 adipocytes exposed to palmitate

Author keywords

Aspalathin; Aspalathus linearis; Dihydrochalcone C glucoside; Insulin resistance; Palmitate

Indexed keywords

ADENOSINE TRIPHOSPHATE; ASPALATHIN; CHALCONE DERIVATIVE; GLUCOSE; GLUCOSE TRANSPORTER 4; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; PALMITIC ACID DERIVATIVE; PLANT EXTRACT; SLC2A4 PROTEIN, MOUSE;

EID: 84941710120     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201500258     Document Type: Article
Times cited : (56)

References (50)
  • 1
    • 84921451583 scopus 로고    scopus 로고
    • Mechanisms of fatty aid-induced insulin resistance in muscle and liver
    • Ragheb, D. R., Mechanisms of fatty aid-induced insulin resistance in muscle and liver. J. Diabetes Metab. 2011, 2, 127
    • (2011) J. Diabetes Metab. , vol.2 , pp. 127
    • Ragheb, D.R.1
  • 2
    • 42449097289 scopus 로고    scopus 로고
    • Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
    • Guilherme, A., Virbasius, J. V., Puri, V., Czech, M. P., Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes. Nat. Rev. Mol. Cell Biol. 2008, 9, 367-377.
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 367-377
    • Guilherme, A.1    Virbasius, J.V.2    Puri, V.3    Czech, M.P.4
  • 3
    • 80053408094 scopus 로고    scopus 로고
    • Fatty acids, obesity, and insulin resistance: time for a reevaluation
    • Karpe, F., Dickmann, J. R., Frayn, K. N., Fatty acids, obesity, and insulin resistance: time for a reevaluation. Diabetes 2011, 60, 2441-2449.
    • (2011) Diabetes , vol.60 , pp. 2441-2449
    • Karpe, F.1    Dickmann, J.R.2    Frayn, K.N.3
  • 4
    • 0028342686 scopus 로고
    • Mechanisms of fatty acid-induced inhibition of glucose uptake
    • Boden, G., Chen, X., Ruiz, J., White, J. V., Rossetti, L., Mechanisms of fatty acid-induced inhibition of glucose uptake. J. Clin. Invest. 1994, 93, 2438-2446.
    • (1994) J. Clin. Invest. , vol.93 , pp. 2438-2446
    • Boden, G.1    Chen, X.2    Ruiz, J.3    White, J.V.4    Rossetti, L.5
  • 6
    • 74949084316 scopus 로고    scopus 로고
    • Membrane fatty acid transporters as regulators of lipid metabolism: implications for metabolic disease
    • Glatz, J. F., Luiken, J. J., Bonen, A., Membrane fatty acid transporters as regulators of lipid metabolism: implications for metabolic disease. Physiol. Rev. 2010, 90, 367-417.
    • (2010) Physiol. Rev. , vol.90 , pp. 367-417
    • Glatz, J.F.1    Luiken, J.J.2    Bonen, A.3
  • 7
    • 81255160750 scopus 로고    scopus 로고
    • Rooibos (Aspalathus linearis) beyond the farm gate: from herbal tea to potential phytopharmaceutical
    • Joubert, E., de Beer, D., Rooibos (Aspalathus linearis) beyond the farm gate: from herbal tea to potential phytopharmaceutical. South African J. Bot. 2011, 77, 869-886.
    • (2011) South African J. Bot. , vol.77 , pp. 869-886
    • Joubert, E.1    de Beer, D.2
  • 8
    • 84870428902 scopus 로고    scopus 로고
    • Acute assessment of an aspalathin-enriched green rooibos (Aspalathus linearis) extract with hypoglycemic potential
    • Muller, C. J. F., Joubert, E., de Beer, D., Sanderson, M. et al., Acute assessment of an aspalathin-enriched green rooibos (Aspalathus linearis) extract with hypoglycemic potential. Phytomedicine 2012, 20, 32-39.
    • (2012) Phytomedicine , vol.20 , pp. 32-39
    • Muller, C.J.F.1    Joubert, E.2    de Beer, D.3    Sanderson, M.4
  • 9
    • 84879885429 scopus 로고    scopus 로고
    • Amelioration of palmitate-induced insulin resistance in C2C12 muscle cells by rooibos (Aspalathus linearis)
    • Mazibuko, S. E., Muller, C. J., Joubert, E., de Beer D. et al., Amelioration of palmitate-induced insulin resistance in C2C12 muscle cells by rooibos (Aspalathus linearis). Phytomedicine 2013, 20, 813-819.
    • (2013) Phytomedicine , vol.20 , pp. 813-819
    • Mazibuko, S.E.1    Muller, C.J.2    Joubert, E.3    de Beer, D.4
  • 10
    • 84892938405 scopus 로고    scopus 로고
    • Effects of fermented rooibos (Aspalathus linearis) on adipocyte differentiation
    • Sanderson, M., Mazibuko, S. E., Joubert, E., de Beer D. et al., Effects of fermented rooibos (Aspalathus linearis) on adipocyte differentiation. Phytomedicine 2014, 21, 109-117.
    • (2014) Phytomedicine , vol.21 , pp. 109-117
    • Sanderson, M.1    Mazibuko, S.E.2    Joubert, E.3    de Beer, D.4
  • 11
    • 64449086955 scopus 로고    scopus 로고
    • Hypoglycemic effect of aspalathin, a rooibos tea component from Aspalathus linearis, in type 2 diabetic model db/db mice
    • Kawano, A., Nakamura, H., Hata, S., Minakawa, M. et al., Hypoglycemic effect of aspalathin, a rooibos tea component from Aspalathus linearis, in type 2 diabetic model db/db mice. Phytomedicine 2009, 16, 437-443
    • (2009) Phytomedicine , vol.16 , pp. 437-443
    • Kawano, A.1    Nakamura, H.2    Hata, S.3    Minakawa, M.4
  • 12
    • 84891836160 scopus 로고    scopus 로고
    • Aspalathin improves hyperglycemia and glucose intolerance in obese diabetic ob/ob mice
    • Son, M. J., Minakawa, M., Miura, Y., Yagasaki, K., Aspalathin improves hyperglycemia and glucose intolerance in obese diabetic ob/ob mice. Eur. J. Nutr. 2013, 52, 1607-1619.
    • (2013) Eur. J. Nutr. , vol.52 , pp. 1607-1619
    • Son, M.J.1    Minakawa, M.2    Miura, Y.3    Yagasaki, K.4
  • 13
    • 78651391894 scopus 로고    scopus 로고
    • Free radicals, antioxidants and functional foods: impact on human health
    • Lobo, V., Patil, A., Phatak, A., Chandra, N., Free radicals, antioxidants and functional foods: impact on human health. Pharmacogn. Rev. 2010, 4, 118-126.
    • (2010) Pharmacogn. Rev. , vol.4 , pp. 118-126
    • Lobo, V.1    Patil, A.2    Phatak, A.3    Chandra, N.4
  • 14
    • 84902083327 scopus 로고    scopus 로고
    • Dietary polyphenols as potential nutraceuticals in management of diabetes: a review
    • Bahadoran, Z., Mirmiran, P., Azizi, F., Dietary polyphenols as potential nutraceuticals in management of diabetes: a review. J. Diabetes Metab. Disord. 2013, 12, 43.
    • (2013) J. Diabetes Metab. Disord. , vol.12 , pp. 43
    • Bahadoran, Z.1    Mirmiran, P.2    Azizi, F.3
  • 15
    • 84897452082 scopus 로고    scopus 로고
    • Concise and scalable synthesis of aspalathin, a powerful plasma sugar-lowering natural product
    • Han, Z., Matthew, C., Achilonu, Pravin, S. et al., Concise and scalable synthesis of aspalathin, a powerful plasma sugar-lowering natural product. J. Nat. Prod. 2014, 77, 583-588.
    • (2014) J. Nat. Prod. , vol.77 , pp. 583-588
    • Han, Z.1    Matthew, C.2    Achilonu3    Pravin, S.4
  • 16
    • 0035937793 scopus 로고    scopus 로고
    • Arachidonic acid stimulates glucose uptake in 3T3-L1 adipocytes by increasing GLUT1 and GLUT4 levels at the plasma membrane. Evidence for involvement of lipoxygenase metabolites and peroxisome proliferator-activated receptor gamma
    • Nugent, C., Prins, J. B., Whitehead, J. P., Wentworth, J. M. et al., Arachidonic acid stimulates glucose uptake in 3T3-L1 adipocytes by increasing GLUT1 and GLUT4 levels at the plasma membrane. Evidence for involvement of lipoxygenase metabolites and peroxisome proliferator-activated receptor gamma. J. Biol. Chem. 2001, 276, 9149-9157.
    • (2001) J. Biol. Chem. , vol.276 , pp. 9149-9157
    • Nugent, C.1    Prins, J.B.2    Whitehead, J.P.3    Wentworth, J.M.4
  • 17
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
    • Mosmann, T., Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983, 65, 55-63.
    • (1983) J. Immunol. Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 18
    • 84866469746 scopus 로고    scopus 로고
    • Western blot: technique, theory, and trouble shooting
    • Mahmood, T., Yang, P. C., Western blot: technique, theory, and trouble shooting. N. Am. J. Med. Sci. 2012, 4, 429-434.
    • (2012) N. Am. J. Med. Sci. , vol.4 , pp. 429-434
    • Mahmood, T.1    Yang, P.C.2
  • 19
    • 84949231160 scopus 로고    scopus 로고
    • In vitro and in vivo effect of Aspalathus linearis and its major polyphenols on carbohydrate and lipid metabolism in insulin resistant models. PhD Thesis
    • Mazibuko, S. E., In vitro and in vivo effect of Aspalathus linearis and its major polyphenols on carbohydrate and lipid metabolism in insulin resistant models. PhD Thesis, 2014. University of Zululand.
    • (2014) University of Zululand
    • Mazibuko, S.E.1
  • 20
    • 0032749509 scopus 로고    scopus 로고
    • Differential effects of palmitate on glucose uptake in rat-1 fibroblasts and 3T3-L1 adipocytes
    • Usui, I., Haruta, T., Takata, Y., Iwata, M. et al., Differential effects of palmitate on glucose uptake in rat-1 fibroblasts and 3T3-L1 adipocytes. Horm. Metab. Res. 1999, 31, 546-552.
    • (1999) Horm. Metab. Res. , vol.31 , pp. 546-552
    • Usui, I.1    Haruta, T.2    Takata, Y.3    Iwata, M.4
  • 21
    • 14644435061 scopus 로고    scopus 로고
    • Differential utilization of saturated palmitate and unsaturated oleate: evidence from cultured myotubes
    • Gaster, M., Rustan, A. C., Beck-Nielsen, H., Differential utilization of saturated palmitate and unsaturated oleate: evidence from cultured myotubes. Diabetes 2005, 54, 648-656.
    • (2005) Diabetes , vol.54 , pp. 648-656
    • Gaster, M.1    Rustan, A.C.2    Beck-Nielsen, H.3
  • 22
    • 84857955247 scopus 로고    scopus 로고
    • Ameliorative effects of polyunsaturated fatty acids against palmitic acid-induced insulin resistance in L6 skeletal muscle cells
    • Sawada, K., Kawabata, K., Yamashita, T., Kawasaki, K. et al., Ameliorative effects of polyunsaturated fatty acids against palmitic acid-induced insulin resistance in L6 skeletal muscle cells. Lipids Health Dis. 2012, 11, 36.
    • (2012) Lipids Health Dis , vol.11 , pp. 36
    • Sawada, K.1    Kawabata, K.2    Yamashita, T.3    Kawasaki, K.4
  • 23
    • 84880183917 scopus 로고    scopus 로고
    • Saturated fatty acid palmitate-induced insulin resistance is accompanied with myotube loss and the impaired expression of health benefit myokine genes in C2C12 myotubes
    • Yang, M., Wei, D., Mo, C., Zhang, J. et al., Saturated fatty acid palmitate-induced insulin resistance is accompanied with myotube loss and the impaired expression of health benefit myokine genes in C2C12 myotubes. Lipids Health Dis. 2013, 12, 104.
    • (2013) Lipids Health Dis , vol.12 , pp. 104
    • Yang, M.1    Wei, D.2    Mo, C.3    Zhang, J.4
  • 24
    • 84890284142 scopus 로고    scopus 로고
    • PI3 kinase directly phosphorylates Akt1/2 at Ser473/474 in the insulin signal transduction pathway
    • Tsuchiya, A., Kanno, T. Nishizaki, T., PI3 kinase directly phosphorylates Akt1/2 at Ser473/474 in the insulin signal transduction pathway. J. Endocrinol. 2014, 220, 49-59.
    • (2014) J. Endocrinol. , vol.220 , pp. 49-59
    • Tsuchiya, A.1    Kanno, T.2    Nishizaki, T.3
  • 25
    • 84886573158 scopus 로고    scopus 로고
    • Resveratrol mainly stimulates the glycolytic ATP synthesis flux and not the mitochondrial one: a saturation transfer NMR study in perfused and isolated rat liver
    • Beauvieux, M. C., Stephant, A., Gin, H., Serhan, N. et al., Resveratrol mainly stimulates the glycolytic ATP synthesis flux and not the mitochondrial one: a saturation transfer NMR study in perfused and isolated rat liver. Pharmacol. Res. 2013, 78, 11-17.
    • (2013) Pharmacol. Res. , vol.78 , pp. 11-17
    • Beauvieux, M.C.1    Stephant, A.2    Gin, H.3    Serhan, N.4
  • 26
    • 78650679662 scopus 로고    scopus 로고
    • Effects of rooibos (Aspalathus linearis) on oxidative stress and biochemical parameters in adults at risk for cardiovascular disease
    • Marnewick, J. L., Rautenbach, F., Venter, I., Neethling, H. et al., Effects of rooibos (Aspalathus linearis) on oxidative stress and biochemical parameters in adults at risk for cardiovascular disease. J. Ethnopharmacol. 2011, 133, 46-52.
    • (2011) J. Ethnopharmacol. , vol.133 , pp. 46-52
    • Marnewick, J.L.1    Rautenbach, F.2    Venter, I.3    Neethling, H.4
  • 27
    • 58649096801 scopus 로고    scopus 로고
    • Saturated fatty acid-mediated inflammation and insulin resistance in adipose tissue: mechanisms of action and implications
    • Kennedy, A., Martinez, K., Chuang, C. C., LaPoint, K. et al., Saturated fatty acid-mediated inflammation and insulin resistance in adipose tissue: mechanisms of action and implications. J. Nutr. 2009, 139, 1-4.
    • (2009) J. Nutr. , vol.139 , pp. 1-4
    • Kennedy, A.1    Martinez, K.2    Chuang, C.C.3    LaPoint, K.4
  • 28
    • 84923264186 scopus 로고    scopus 로고
    • Hypochlorous acid via peroxynitrite activates protein kinase Cθ and insulin resistance in adipocytes
    • Zhou, J., Wang, Q., Ding, Y., Zou, M. H., Hypochlorous acid via peroxynitrite activates protein kinase Cθ and insulin resistance in adipocytes. J. Mol. Endocrinol. 2015, 54, 25-37.
    • (2015) J. Mol. Endocrinol. , vol.54 , pp. 25-37
    • Zhou, J.1    Wang, Q.2    Ding, Y.3    Zou, M.H.4
  • 29
    • 33750572410 scopus 로고    scopus 로고
    • Differential effects of palmitate and palmitoleate on insulin action and glucose utilization in rat L6 skeletal muscle cells
    • Dimopoulos, N., Watson, M., Sakamoto, K., Hundal, H. S., Differential effects of palmitate and palmitoleate on insulin action and glucose utilization in rat L6 skeletal muscle cells. Biochem. J. 2006, 399, 473-481.
    • (2006) Biochem. J. , vol.399 , pp. 473-481
    • Dimopoulos, N.1    Watson, M.2    Sakamoto, K.3    Hundal, H.S.4
  • 30
    • 84863062486 scopus 로고    scopus 로고
    • Suppression of free fatty acid-induced insulin resistance by phytopolyphenols in C2C12 mouse skeletal muscle cells
    • Deng, Y.-T., Chang, T. W., Lee, M. S., Lin, J. K., Suppression of free fatty acid-induced insulin resistance by phytopolyphenols in C2C12 mouse skeletal muscle cells. J. Agric. Food Chem. 2012, 60, 1059-1066.
    • (2012) J. Agric. Food Chem. , vol.60 , pp. 1059-1066
    • Deng, Y.-T.1    Chang, T.W.2    Lee, M.S.3    Lin, J.K.4
  • 31
    • 84862989884 scopus 로고    scopus 로고
    • Astragalus polysaccharide improves palmitate-induced insulin resistance by inhibiting PTP1B and NF-κB in C2C12 myotubes
    • Zhao, M., Zhang, Z. F., Ding, Y., Wang, J. B. et al., Astragalus polysaccharide improves palmitate-induced insulin resistance by inhibiting PTP1B and NF-κB in C2C12 myotubes. Molecules 2012, 17, 7083-7092.
    • (2012) Molecules , vol.17 , pp. 7083-7092
    • Zhao, M.1    Zhang, Z.F.2    Ding, Y.3    Wang, J.B.4
  • 32
    • 74949121815 scopus 로고    scopus 로고
    • AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC
    • Sajan, M. P., Bandyopadhyay, G., Miura, A., Standaert, M. L. et al., AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC. Am. J. Physiol. Endocrinol. Metab. 2010, 298, E179-E192.
    • (2010) Am. J. Physiol. Endocrinol. Metab. , vol.298 , pp. E179-E192
    • Sajan, M.P.1    Bandyopadhyay, G.2    Miura, A.3    Standaert, M.L.4
  • 33
    • 33646865041 scopus 로고    scopus 로고
    • Insulin resistance and improvements in signal transduction
    • Musi, N., Goodyear, L. J., Insulin resistance and improvements in signal transduction. Endocrine 2006, 29, 73-80.
    • (2006) Endocrine , vol.29 , pp. 73-80
    • Musi, N.1    Goodyear, L.J.2
  • 34
    • 33244493944 scopus 로고    scopus 로고
    • Regulation of AMP-activated protein kinase and acetyl-CoA carboxylase phosphorylation by palmitate in skeletal muscle cells
    • Fediuc, S., Gaidhu, M. P., Ceddia, R. B., Regulation of AMP-activated protein kinase and acetyl-CoA carboxylase phosphorylation by palmitate in skeletal muscle cells. J. Lipid Res. 2006, 47, 412-420.
    • (2006) J. Lipid Res. , vol.47 , pp. 412-420
    • Fediuc, S.1    Gaidhu, M.P.2    Ceddia, R.B.3
  • 35
    • 33745214270 scopus 로고    scopus 로고
    • Fatty acids stimulate AMP-activated protein kinase and enhance fatty acid oxidation in L6 myotubes
    • Watt, M. J., Steinberg, G. R., Chen, Z. P., Kemp, B. E. et al., Fatty acids stimulate AMP-activated protein kinase and enhance fatty acid oxidation in L6 myotubes. J. Physiol. 2006, 574, 139-147.
    • (2006) J. Physiol. , vol.574 , pp. 139-147
    • Watt, M.J.1    Steinberg, G.R.2    Chen, Z.P.3    Kemp, B.E.4
  • 36
    • 84872741363 scopus 로고    scopus 로고
    • Acute regulation of 5'-AMP-activated protein kinase by long-chain fatty acid, glucose and insulin in rat primary adipocytes
    • Hebbachi, A., Saggerson, D., Acute regulation of 5'-AMP-activated protein kinase by long-chain fatty acid, glucose and insulin in rat primary adipocytes. Biosci. Rep. 2013, 33, 71-82.
    • (2013) Biosci. Rep. , vol.33 , pp. 71-82
    • Hebbachi, A.1    Saggerson, D.2
  • 37
    • 67649394135 scopus 로고    scopus 로고
    • Culinary plants, herbs and spices-a rich source of PPARγ ligands
    • Mueller, M., Jungbauer, A., Culinary plants, herbs and spices-a rich source of PPARγ ligands. Food Chem. 2009, 117, 660-667.
    • (2009) Food Chem , vol.117 , pp. 660-667
    • Mueller, M.1    Jungbauer, A.2
  • 38
    • 39649087113 scopus 로고    scopus 로고
    • Kaempferol and quercetin isolated from Euonymus alatus improve glucose uptake of 3T3-L1 cells without adipogenesis activity
    • Fang, X. K., Gao, J., Zhu, D. N., Kaempferol and quercetin isolated from Euonymus alatus improve glucose uptake of 3T3-L1 cells without adipogenesis activity. Life Sci. 2008, 82, 615-622.
    • (2008) Life Sci , vol.82 , pp. 615-622
    • Fang, X.K.1    Gao, J.2    Zhu, D.N.3
  • 39
    • 78651290317 scopus 로고    scopus 로고
    • Quercetin is equally or more effective than resveratrol in attenuating tumor necrosis factor-(alpha)-mediated inflammation and insulin resistance in primary human adipocytes
    • 1511-1121
    • Chuang, C. C., Martinez, K., Xie, G., Kenned, A. et al., Quercetin is equally or more effective than resveratrol in attenuating tumor necrosis factor-(alpha)-mediated inflammation and insulin resistance in primary human adipocytes. Am. J. Clin. Nutr. 2010, 92, 1511-1121.
    • (2010) Am. J. Clin. Nutr. , vol.92
    • Chuang, C.C.1    Martinez, K.2    Xie, G.3    Kenned, A.4
  • 40
    • 76049086229 scopus 로고    scopus 로고
    • PPARgamma activation in adipocytes is sufficient for systemic insulin sensitization
    • Sugii, S., Olson, P., Sears, D. D., Saberi, M. et al., PPARgamma activation in adipocytes is sufficient for systemic insulin sensitization. Proc. Natl. Acad. Sci. USA 2009, 106, 22504-22509.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 22504-22509
    • Sugii, S.1    Olson, P.2    Sears, D.D.3    Saberi, M.4
  • 41
    • 23044467570 scopus 로고    scopus 로고
    • Anti-diabetic action of Punica granatum flower extract: activation of PPAR-γ and identification of an active component
    • Huang, T. H., Peng, G., Kota, B. P., Li, G. Q. et al., Anti-diabetic action of Punica granatum flower extract: activation of PPAR-γ and identification of an active component. Toxicol. Appl. Pharmacol. 2005, 207, 160-169.
    • (2005) Toxicol. Appl. Pharmacol. , vol.207 , pp. 160-169
    • Huang, T.H.1    Peng, G.2    Kota, B.P.3    Li, G.Q.4
  • 42
    • 58149170595 scopus 로고    scopus 로고
    • Improved insulin resistance and lipid metabolism by cinnamon extract through activation of peroxisome proliferator-activated receptors
    • 581348
    • Sheng, X., Zhang, Y., Gong, Z., Huang, C. et al., Improved insulin resistance and lipid metabolism by cinnamon extract through activation of peroxisome proliferator-activated receptors. PPAR Res. 2008, 581348, 1-9.
    • (2008) PPAR Res , pp. 1-9
    • Sheng, X.1    Zhang, Y.2    Gong, Z.3    Huang, C.4
  • 44
    • 21644455008 scopus 로고    scopus 로고
    • Anti-lipolytic action of AMP-activated protein kinase in rodent adipocytes
    • Daval, M. Diot-Dupuy, F., Bazin, R., Hainault, I. et al., Anti-lipolytic action of AMP-activated protein kinase in rodent adipocytes. J. Biol. Chem. 2005, 280, 25250-25257.
    • (2005) J. Biol. Chem. , vol.280 , pp. 25250-25257
    • Daval, M.1    Diot-Dupuy, F.2    Bazin, R.3    Hainault, I.4
  • 45
    • 41349114428 scopus 로고    scopus 로고
    • Eicosapentaenoic acid increases lipolysis through up-regulation of the lipolytic gene expression and down-regulation of the adipogenic gene expression in 3T3-L1 adipocytes
    • Lee, M. S., Kwun, I. S., Kim, Y., Eicosapentaenoic acid increases lipolysis through up-regulation of the lipolytic gene expression and down-regulation of the adipogenic gene expression in 3T3-L1 adipocytes. Genes Nutr. 2008, 2, 327-330.
    • (2008) Genes Nutr , vol.2 , pp. 327-330
    • Lee, M.S.1    Kwun, I.S.2    Kim, Y.3
  • 46
    • 0036896836 scopus 로고    scopus 로고
    • Malonyl coenzyme A and the regulation of functional carnitine palmitoyltransferase-1 activity and fat oxidation in human skeletal muscle
    • Rasmussen, B. B., Holmbäck, U. C., Volpi, E., Morio-Liondore, B. et al., Malonyl coenzyme A and the regulation of functional carnitine palmitoyltransferase-1 activity and fat oxidation in human skeletal muscle. J. Clin. Invest. 2002, 110, 1687-1693.
    • (2002) J. Clin. Invest. , vol.110 , pp. 1687-1693
    • Rasmussen, B.B.1    Holmbäck, U.C.2    Volpi, E.3    Morio-Liondore, B.4
  • 47
    • 46749146865 scopus 로고    scopus 로고
    • Carnitine palmitoyltransferase 1: central to cell function
    • Zammit, V. A., Carnitine palmitoyltransferase 1: central to cell function. IUBMB Life 2008, 60, 347-354.
    • (2008) IUBMB Life , vol.60 , pp. 347-354
    • Zammit, V.A.1
  • 48
    • 79957855436 scopus 로고    scopus 로고
    • Anti-Obesity and anti-diabetic effects of Acacia polyphenol in obese diabetic KKAy mice fed high-fat diet
    • 952031
    • Ikarashi, N. Toda, T., Okaniwa, T., Ito, K. et al., Anti-Obesity and anti-diabetic effects of Acacia polyphenol in obese diabetic KKAy mice fed high-fat diet. Evid. Based. Complement. Alternat. Med. 2011, 952031, 1-9.
    • (2011) Evid. Based. Complement. Alternat. Med , pp. 1-9
    • Ikarashi, N.1    Toda, T.2    Okaniwa, T.3    Ito, K.4
  • 49
    • 84893814280 scopus 로고    scopus 로고
    • Antiobesity effects of an edible halophyte Nitraria retusa forssk in 3T3-L1 preadipocyte differentiation and in C57B6J/L mice fed a high fat diet-induced obesity
    • 368658
    • Zar Kalai, F., Han, J., Ksouri, R., Omri, A. E. et al., Antiobesity effects of an edible halophyte Nitraria retusa forssk in 3T3-L1 preadipocyte differentiation and in C57B6J/L mice fed a high fat diet-induced obesity. Evidence-Based Complement. Altern. Med. 2013, 368658, 1-11.
    • (2013) Evidence-Based Complement. Altern. Med , pp. 1-11
    • Zar Kalai, F.1    Han, J.2    Ksouri, R.3    Omri, A.E.4
  • 50
    • 78049353457 scopus 로고    scopus 로고
    • Palmitate-induced down-regulation of sortilin and impaired GLUT4 trafficking in C2C12 Myotubes
    • Tsuchiya, Y. Hatakeyama, H., Emoto, N., Wagatsuma, F. et al., Palmitate-induced down-regulation of sortilin and impaired GLUT4 trafficking in C2C12 Myotubes. J. Biol. Chem. 2010, 285, 34371-34381.
    • (2010) J. Biol. Chem. , vol.285 , pp. 34371-34381
    • Tsuchiya, Y.1    Hatakeyama, H.2    Emoto, N.3    Wagatsuma, F.4


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