Decreased core crystallinity facilitated drug loading in polymeric micelles without affecting their biological performances

Biomacromolecules

Volumn 16, Issue 9, 2015, Pages 2920-2929

  Gou, Jingxin ^a   Feng, Shuangshuang ^a   Xu, Helin ^a   Fang, Guihua ^a   Chao, Yanhui ^a   Zhang, Yu ^a   Xu, Hui ^a   Tang, Xing ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG PRODUCTS; MICELLES; PARTICLE SIZE;

BIOLOGICAL PERFORMANCE; CONTROLLED PARTICLE SIZES; CORE CONSTRUCTION; DRUG-RELEASE RATE; LOADING CAPACITIES; MEDIUM CHAIN TRIGLYCERIDES; POLARIZED MICROSCOPE; POLYMERIC MICELLE;

POLYMERS;

CABAZITAXEL; DISULFIRAM; MEDIUM CHAIN TRIACYLGLYCEROL; TAXANE DERIVATIVE; 13-(N-TERT-BUTOXYCARBONYL-3-ISOBUTYLISOSERINOYL-4,10-DIACETOXY-2-BENZOYLOXY-5-20-EPOXY-1,13-DIHYDROXY-9-OXO-19-NORCYCLOPROPA(G)TAX-11-ENE; DRUG CARRIER; MICELLE; TAXOID; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ARTICLE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CRYSTALLIZATION; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG STABILITY; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; LIGHT SCATTERING; MALE; MICELLE; MOLECULAR WEIGHT; NONHUMAN; PARTICLE SIZE; PHARMACOKINETIC PARAMETERS; PHASE SEPARATION; POLARIZATION MICROSCOPY; POLYMERIZATION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; ROOM TEMPERATURE; SURFACE PROPERTY; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ANIMAL; CELL LINE; CHEMISTRY; SPRAGUE DAWLEY RAT;

ANIMALS; CELL LINE; DISULFIRAM; DRUG CARRIERS; MICELLES; RATS; RATS, SPRAGUE-DAWLEY; TAXOIDS; TRIGLYCERIDES;

EID: 84941702857     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/acs.biomac.5b00826     Document Type: Article

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