Selective redox-responsive drug release in tumor cells mediated by chitosan based glycolipid-like nanocarrier

Journal of Controlled Release

Volumn 206, Issue , 2015, Pages 91-100

  Hu, Ying Wen ^a   Du, Yong Zhong ^a   Liu, Na ^a   Liu, Xuan ^a   Meng, Ting Ting ^a   Cheng, Bo Lin ^a   He, Jia Bei ^a   You, Jian ^a   Yuan, Hong ^a   Hu, Fu Qiang ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Chitosan; Drug delivery; Redox responsive; Smart polymer; Triggered release; Tumor targeting

Indexed keywords

CELLS; CHITIN; CHITOSAN; CYTOLOGY; DRUG DELIVERY; MOBILE SECURITY;

DRUG DELIVERY SYSTEM; POSITIVE CORRELATIONS; REDOX-RESPONSIVE; REDUCING ENVIRONMENT; SMART POLYMERS; TRIGGERED DRUG RELEASE; TRIGGERED RELEASE; TUMOR TARGETING;

TUMORS;

CHITOSAN NANOPARTICLE; GENERIC DRUG; GLUTATHIONE; GLYCOLIPID; NANOCARRIER; PACLITAXEL; CHITOSAN; DELAYED RELEASE FORMULATION; MICELLE; STEARIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CHEMOTHERAPY; CANCER INHIBITION; CELL VIABILITY; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CRITICAL MICELLE CONCENTRATION; DRUG CYTOTOXICITY; DRUG DEGRADATION; DRUG DISTRIBUTION; DRUG TRANSPORT; DRUG UPTAKE; EXTRACELLULAR MATRIX; FEMALE; HUMAN; HUMAN CELL; HYDROPHOBICITY; INTERNALIZATION; LOW DRUG DOSE; MOLECULAR WEIGHT; MOUSE; NANOENCAPSULATION; NONHUMAN; NORMAL HUMAN; OVARIAN CANCER CELL LINE; OVARY CARCINOMA; PARTICLE SIZE; PRIORITY JOURNAL; REDUCTION; SLOW DRUG RELEASE; TRANSMISSION ELECTRON MICROSCOPY; TUMOR VOLUME; TUMOR XENOGRAFT; ANALOGS AND DERIVATIVES; ANIMAL; BAGG ALBINO MOUSE; CELL LINE; CHEMISTRY; DELAYED RELEASE FORMULATION; DRUG DELIVERY SYSTEM; DRUG RELEASE; METABOLISM; MICELLE; OVARIAN NEOPLASMS; OXIDATION REDUCTION REACTION; TUMOR CELL LINE;

ANIMALS; CELL LINE; CELL LINE, TUMOR; CHITOSAN; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; DRUG LIBERATION; FEMALE; GLYCOLIPIDS; HUMANS; MICE, INBRED BALB C; MICELLES; OVARIAN NEOPLASMS; OXIDATION-REDUCTION; STEARIC ACIDS;

EID: 84925457321     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.03.018     Document Type: Article

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