In silico analysis and experimental validation of active compounds from cichorium intybus l. Ameliorating liver injury

International Journal of Molecular Sciences

Volumn 16, Issue 9, 2015, Pages 22190-22204

  Li, Guo Yu ^a   Zheng, Ya Xin ^b   Sun, Fu Zhou ^b   Huang, Jian ^b   Lou, Meng Meng ^c   Gu, Jing Kai ^a   Wang, Jin Hui ^b,c  

^a JILIN UNIVERSITY   (China)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^c SHIHEZI UNIVERSITY   (China)

Author keywords

Acute liver injury; Akt 1; Caspase 1; Cichorium intybus L; In silico analysis

Indexed keywords

3AR SANTAMARINE; 4 HYDROXYLPHENYLACETIC ACID; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; AURANTIAMIDE ACETATE; CAFFEIC ACID; CICHORIUM INTYBUS EXTRACT; GLUTATHIONE; INTERLEUKIN 1BETA CONVERTING ENZYME; INTYBOATE B; LUTEOLIN; LUTEOLIN 7 GLUCOSIDE; MALONALDEHYDE; METHYL 4 HYDROXYPHENYLACETATE; PLANT EXTRACT; PROTEIN KINASE B; PROTEIN KINASE B ALPHA; REACTIVE OXYGEN METABOLITE; SILIBININ; SITOGLUSIDE; SITOSTEROL; UNCLASSIFIED DRUG; AKT1 PROTEIN, MOUSE; MOLECULAR LIBRARY; PROTEIN BINDING;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CHEMICAL COMPOSITION; CHEMICAL STRUCTURE; CHICORY; COMPUTER MODEL; CONTROLLED STUDY; CYTOLOGY; DRUG EFFICACY; FLOW CYTOMETRY; HISTOPATHOLOGY; IN VITRO STUDY; LIVER CELL; LIVER INJURY; LIVER PROTECTION; MALE; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR MODEL; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTON NUCLEAR MAGNETIC RESONANCE; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; WESTERN BLOTTING; ANIMAL; BINDING SITE; CHEMICAL AND DRUG INDUCED LIVER INJURY; CHEMISTRY; DRUG EFFECTS; GENETICS; LIVER; METABOLISM; MOLECULAR LIBRARY; PHARMACOLOGY;

ANIMALS; APOPTOSIS; AUTOPHAGY; BINDING SITES; CASPASE 1; CHEMICAL AND DRUG INDUCED LIVER INJURY; CHICORY; LIVER; MICE; MOLECULAR DOCKING SIMULATION; PLANT EXTRACTS; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-AKT; SMALL MOLECULE LIBRARIES;

EID: 84941695617     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms160922190     Document Type: Article

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