Mode of interaction of TRIP13 AAA-ATPase with the Mad2-binding protein p31comet and with mitotic checkpoint complexes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 37, 2015, Pages 11536-11540

  Miniowitz Shemtov, Shirly ^a   Eytan, Ety ^a   Kaisari, Sharon ^a   Sitry Shevah, Danielle ^a   Hershko, Avram ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

Cell cycle; Mitosis; Spindle checkpoint

Indexed keywords

AAA ATPASE THYROID HORMONE RECEPTOR INTERACTING PROTEIN 13; ADENOSINE TRIPHOSPHATE DERIVATIVE; BINDING PROTEIN; BINDING PROTEIN P31; BUB1 RELATED PROTEIN; BUB3 PROTEIN; CELL CYCLE PROTEIN 20; CELL PROTEIN; PROTEIN MAD2; UNCLASSIFIED DRUG; ADENOSINE 5'-O-(3-THIOTRIPHOSPHATE); ADENOSINE TRIPHOSPHATE; ANAPHASE PROMOTING COMPLEX; CARRIER PROTEIN; CELL CYCLE PROTEIN; MAD2L1BP PROTEIN, HUMAN; NUCLEAR PROTEIN; PROTEIN BINDING; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TRIP13 PROTEIN, HUMAN;

ANAPHASE; ARTICLE; CHROMOSOME SEGREGATION; FEMALE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; M PHASE CELL CYCLE CHECKPOINT; MITOSIS; MITOSIS SPINDLE; MOLECULAR SIZE; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SIZE EXCLUSION CHROMATOGRAPHY; ANALOGS AND DERIVATIVES; APOPTOSIS; CHEMISTRY; GENE EXPRESSION REGULATION; HELA CELL LINE; METABOLISM; SPINDLE APPARATUS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOSINE TRIPHOSPHATE; ANAPHASE-PROMOTING COMPLEX-CYCLOSOME; APOPTOSIS; CARRIER PROTEINS; CELL CYCLE PROTEINS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HELA CELLS; HUMANS; IMMUNOPRECIPITATION; MAD2 PROTEINS; MITOSIS; NUCLEAR PROTEINS; PROTEIN BINDING; PROTEIN CONFORMATION; SPINDLE APPARATUS;

EID: 84941671299     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1515358112     Document Type: Article

References (19)

1. Eytan E, et al. (2014) Disassembly of mitotic checkpoint complexes by the joint action of the AAA-ATPase TRIP13 and p31(comet). Proc Natl Acad Sci USA 111(33): 12019-12024.
2. Wang K, et al. (2014) Thyroid hormone receptor interacting protein 13 (TRIP13) AAA-ATPase is a novel mitotic checkpoint-silencing protein. J Biol Chem 289(34): 23928-23937.
3. Musacchio A, Salmon ED (2007) The spindle-assembly checkpoint in space and time. Nat Rev Mol Cell Biol 8(5):379-393.
4. Lara-Gonzalez P, Westhorpe FG, Taylor SS (2012) The spindle assembly checkpoint. Curr Biol 22(22):R966-R980.
5. Jia L, Kim S, Yu H (2013) Tracking spindle checkpoint signals from kinetochores to APC/C. Trends Biochem Sci 38(6):302-311.
6. Chang L, Barford D (2014) Insights into the anaphase-promoting complex: A molecular machine that regulates mitosis. Curr Opin Struct Biol 29:1-9.
7. Miniowitz-Shemtov S, Teichner A, Sitry-Shevah D, Hershko A (2010) ATP is required for the release of the anaphase-promoting complex/cyclosome from inhibition by the mitotic checkpoint. Proc Natl Acad Sci USA 107(12):5351-5356.
8. Teichner A, et al. (2011) p31comet Promotes disassembly of the mitotic checkpoint complex in an ATP-dependent process. Proc Natl Acad Sci USA 108(8):3187-3192.
9. Habu T, Kim SH, Weinstein J, Matsumoto T (2002) Identification of a MAD2-binding protein, CMT2, and its role in mitosis. EMBO J 21(23):6419-6428.
10. Ye Q, et al. (2015) TRIP13 is a protein-remodeling AAA+ ATPase that catalyzes MAD2 conformation switching. eLife 4:4.
11. Tipton AR, et al. (2012) Identification of novel mitosis regulators through data mining with human centromere/kinetochore proteins as group queries. BMC Cell Biol 13:15.
12. Xia G, et al. (2004) Conformation-specific binding of p31(comet) antagonizes the function of Mad2 in the spindle checkpoint. EMBO J 23(15):3133-3143.
13. Vale RD (2000) AAA proteins: Lords of the ring. J Cell Biol 150(1):F13-F19.
14. Chao WC, Kulkarni K, Zhang Z, Kong EH, Barford D (2012) Structure of the mitotic checkpoint complex. Nature 484(7393):208-213.
15. Cheung KL, Huen J, Houry WA, Ortega J (2010) Comparison of the multiple oligomeric structures observed for the Rvb1 and Rvb2 proteins. Biochem Cell Biol 88(1):77-88.
16. López-Perrote A, Muñoz-Hernández H, Gil D, Llorca O (2012) Conformational transitions regulate the exposure of a DNA-binding domain in the RuvBL1-RuvBL2 complex. Nucleic Acids Res 40(21):11086-11099.
17. Ogura T, Wilkinson AJ (2001) AAA+ superfamily ATPases: Common structure-diverse function. Genes Cells 6(7):575-597.
18. Hanson PI, Whiteheart SW (2005) AAA+ proteins: Have engine, will work. Nat Rev Mol Cell Biol 6(7):519-529.
19. Braunstein I, Miniowitz S, Moshe Y, Hershko A (2007) Inhibitory factors associated with anaphase-promoting complex/cylosome in mitotic checkpoint. Proc Natl Acad Sci USA 104(12):4870-4875.