DNA replication stress underlies renal phenotypes in CEP290-Associated Joubert syndrome

Journal of Clinical Investigation

Volumn 125, Issue 9, 2015, Pages 3657-3666

  Slaats, Gisela G ^a,b   Saldivar, Joshua C ^b   Bacal, Julien ^b   Zeman, Michelle K ^b   Kile, Andrew C ^b   Hynes, Ann Marie ^c   Srivastava, Shalabh ^c   Nazmutdinova, Jekaterina ^a,d   Den Ouden, Krista ^a   Zagers, Miriam S ^a   Foletto, Veronica ^a   Verhaar, Marianne C ^a   Miles, Colin ^c   Sayer, John A ^c   Cimprich, Karlene A ^b   Giles, Rachel H ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CENTROSOMAL PROTEIN 290; CYCLIN A; CYCLIN B; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; DNA; DOUBLE STRANDED DNA; PROTEIN; UNCLASSIFIED DRUG; CENTROSOMAL PROTEIN 290, ZEBRAFISH; CEP290 PROTEIN, HUMAN; CEP290 PROTEIN, MOUSE; MICROTUBULE ASSOCIATED PROTEIN; NUCLEAR PROTEIN; TUMOR ANTIGEN; TUMOR PROTEIN; ZEBRAFISH PROTEIN;

AFFECT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CYCLE S PHASE; CENTRIOLE; CONTROLLED STUDY; DNA CONTENT; DNA DAMAGE; DNA FRAGMENTATION; DNA REPLICATION; DNA STRAND BREAKAGE; FEMALE; GENETIC ASSOCIATION; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; JOUBERT SYNDROME; MALE; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; WESTERN BLOTTING; ZEBRA FISH; ANIMAL; CELL LINE; CEREBELLUM; CONGENITAL MALFORMATION; EYE MALFORMATION; GENETICS; KIDNEY; KIDNEY POLYCYSTIC DISEASE; METABOLISM; MULTIPLE MALFORMATION SYNDROME; PATHOLOGY; RETINA;

ABNORMALITIES, MULTIPLE; ANIMALS; ANTIGENS, NEOPLASM; CELL LINE; CENTRIOLES; CEREBELLUM; DNA DAMAGE; DNA REPLICATION; EYE ABNORMALITIES; HUMANS; KIDNEY; KIDNEY DISEASES, CYSTIC; MICE; MICROTUBULE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; NUCLEAR PROTEINS; RETINA; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84941651263     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI80657     Document Type: Article

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