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Volumn 148, Issue 3, 2015, Pages 618-629

Airway IL-1β and systemic inflammation as predictors of future exacerbation risk in asthma and COPD

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; C REACTIVE PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6;

EID: 84941618361     PISSN: 00123692     EISSN: 19313543     Source Type: Journal    
DOI: 10.1378/chest.14-2337     Document Type: Conference Paper
Times cited : (94)

References (33)
  • 1
    • 1842671720 scopus 로고    scopus 로고
    • Outcomes following acute exacerbation of severe chronic obstructive lung disease
    • The SUPPORT investigators (Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments)
    • Connors AF Jr, Dawson NV, Thomas C, et al. Outcomes following acute exacerbation of severe chronic obstructive lung disease. The SUPPORT investigators (Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments). Am J Respir Crit Care Med. 1996; 154 ( 4 pt 1): 959-967.
    • (1996) Am J Respir Crit Care Med. , vol.154 , Issue.4 , pp. 959-967
    • Connors, A.F.1    Dawson, N.V.2    Thomas, C.3
  • 2
    • 84859999746 scopus 로고    scopus 로고
    • Exacerbations of severe asthma
    • McDonald VM, Gibson PG. Exacerbations of severe asthma. Clin Exp Allergy. 2012; 42 ( 5): 670-677.
    • (2012) Clin Exp Allergy. , vol.42 , Issue.5 , pp. 670-677
    • McDonald, V.M.1    Gibson, P.G.2
  • 3
    • 35949002726 scopus 로고    scopus 로고
    • Severe exacerbations predict excess lung function decline in asthma
    • Bai TR, Vonk JM, Postma DS, Boezen HM. Severe exacerbations predict excess lung function decline in asthma. Eur Respir J. 2007; 30 ( 3): 452-456.
    • (2007) Eur Respir J. , vol.30 , Issue.3 , pp. 452-456
    • Bai, T.R.1    Vonk, J.M.2    Postma, D.S.3    Boezen, H.M.4
  • 4
    • 0036794862 scopus 로고    scopus 로고
    • Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease
    • Donaldson GC, Seemungal TA, Bhowmik A, Wedzicha JA. Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease. Thorax. 2002; 57 ( 10): 847-852.
    • (2002) Thorax. , vol.57 , Issue.10 , pp. 847-852
    • Donaldson, G.C.1    Seemungal, T.A.2    Bhowmik, A.3    Wedzicha, J.A.4
  • 5
    • 84892747788 scopus 로고    scopus 로고
    • Frequent exacerbators-A distinct phenotype of severe asthma
    • Kupczyk M, ten Brinke A, Sterk PJ, et al; BIOAIR investigators. Frequent exacerbators-A distinct phenotype of severe asthma. Clin Exp Allergy. 2014; 44 ( 2): 212-221.
    • (2014) Clin Exp Allergy. , vol.44 , Issue.2 , pp. 212-221
    • Kupczyk, M.1    Ten Brinke, A.2    Sterk, P.J.3
  • 6
    • 2442552129 scopus 로고    scopus 로고
    • Impact of preventing exacerbations on deterioration of health status in COPD
    • Spencer S, Calverley PM, Burge PS, Jones PW. Impact of preventing exacerbations on deterioration of health status in COPD. Eur Respir J. 2004; 23 ( 5): 698-702.
    • (2004) Eur Respir J. , vol.23 , Issue.5 , pp. 698-702
    • Spencer, S.1    Calverley, P.M.2    Burge, P.S.3    Jones, P.W.4
  • 7
    • 58849162826 scopus 로고    scopus 로고
    • Acute exacerbations of asthma: Epidemiology, biology and the exacerbation-prone phenotype
    • Dougherty RH, Fahy JV. Acute exacerbations of asthma: epidemiology, biology and the exacerbation-prone phenotype. Clin Exp Allergy. 2009; 39 ( 2): 193-202.
    • (2009) Clin Exp Allergy. , vol.39 , Issue.2 , pp. 193-202
    • Dougherty, R.H.1    Fahy, J.V.2
  • 8
    • 77956689733 scopus 로고    scopus 로고
    • Susceptibility to exacerbation in chronic obstructive pulmonary disease
    • Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators
    • Hurst JR, Vestbo J, Anzueto A, et al; Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators. Susceptibility to exacerbation in chronic obstructive pulmonary disease. N Engl J Med. 2010; 363 ( 12): 1128-1138.
    • (2010) N Engl J Med. , vol.363 , Issue.12 , pp. 1128-1138
    • Hurst, J.R.1    Vestbo, J.2    Anzueto, A.3
  • 9
    • 27744437460 scopus 로고    scopus 로고
    • Risk factors of frequent exacerbations in diffi cult-to-treat asthma
    • ten Brinke A, Sterk PJ, Masclee AA, et al. Risk factors of frequent exacerbations in diffi cult-to-treat asthma. Eur Respir J. 2005; 26 ( 5): 812-818.
    • (2005) Eur Respir J. , vol.26 , Issue.5 , pp. 812-818
    • Ten Brinke, A.1    Sterk, P.J.2    Masclee, A.A.3
  • 10
    • 85047695734 scopus 로고    scopus 로고
    • Clinical phenotypes of COPD: Identifi cation, defi nition and implications for guidelines
    • Miravitlles M, Calle M, Soler-Cataluña JJ. Clinical phenotypes of COPD: identifi cation, defi nition and implications for guidelines. Arch Bronconeumol. 2012; 48 ( 3): 86-98.
    • (2012) Arch Bronconeumol. , vol.48 , Issue.3 , pp. 86-98
    • Miravitlles, M.1    Calle, M.2    Soler-Cataluña, J.J.3
  • 12
    • 84863797299 scopus 로고    scopus 로고
    • The neutrophilic infl ammatory phenotype is associated with systemic infl ammation in asthma
    • Wood LG, Baines KJ, Fu J, Scott HA, Gibson PG. The neutrophilic infl ammatory phenotype is associated with systemic infl ammation in asthma. Chest. 2012; 142 ( 1): 86-93.
    • (2012) Chest. , vol.142 , Issue.1 , pp. 86-93
    • Wood, L.G.1    Baines, K.J.2    Fu, J.3    Scott, H.A.4    Gibson, P.G.5
  • 13
    • 27144526596 scopus 로고    scopus 로고
    • Airway and systemic infl ammation and decline in lung function in patients with COPD
    • Donaldson GC, Seemungal TA, Patel IS, et al. Airway and systemic infl ammation and decline in lung function in patients with COPD. Chest. 2005; 128( 4): 1995-2004.
    • (2005) Chest. , vol.128 , Issue.4 , pp. 1995-2004
    • Donaldson, G.C.1    Seemungal, T.A.2    Patel, I.S.3
  • 15
    • 84862100999 scopus 로고    scopus 로고
    • Persistent systemic infl ammation is associated with poor clinical outcomes in COPD: A novel phenotype
    • Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators
    • Agustí A, Edwards LD, Rennard SI, et al; Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators. Persistent systemic infl ammation is associated with poor clinical outcomes in COPD: A novel phenotype. PLoS ONE. 2012; 7 ( 5): e37483.
    • (2012) PLoS ONE. , vol.7 , Issue.5 , pp. e37483
    • Agustí, A.1    Edwards, L.D.2    Rennard, S.I.3
  • 16
    • 84878867004 scopus 로고    scopus 로고
    • Infl ammatory biomarkers and exacerbations in chronic obstructive pulmonary disease
    • Thomsen M, Ingebrigtsen TS, Marott JL, et al. Infl ammatory biomarkers and exacerbations in chronic obstructive pulmonary disease. J AMA. 2013; 309 ( 22): 2353-2361.
    • (2013) J AMA. , vol.309 , Issue.22 , pp. 2353-2361
    • Thomsen, M.1    Ingebrigtsen, T.S.2    Marott, J.L.3
  • 17
    • 0027404545 scopus 로고
    • Independent binding of interleukin-1 alpha and interleukin-1 beta to type i and type II interleukin-1 receptors
    • Slack J, McMahan CJ, Waugh S, et al. Independent binding of interleukin-1 alpha and interleukin-1 beta to type I and type II interleukin-1 receptors. J Biol Chem. 1993; 268 ( 4): 2513-2524.
    • (1993) J Biol Chem. , vol.268 , Issue.4 , pp. 2513-2524
    • Slack, J.1    McMahan, C.J.2    Waugh, S.3
  • 18
    • 78650864775 scopus 로고    scopus 로고
    • Transcriptional phenotypes of asthma defi ned by gene expression profi ling of induced sputum samples
    • Baines KJ, Simpson JL, Wood LG, Scott RJ, Gibson PG. Transcriptional phenotypes of asthma defi ned by gene expression profi ling of induced sputum samples. J Allergy Clin Immunol. 2011;127(1):153-160.
    • (2011) J Allergy Clin Immunol. , vol.127 , Issue.1 , pp. 153-160
    • Baines, K.J.1    Simpson, J.L.2    Wood, L.G.3    Scott, R.J.4    Gibson, P.G.5
  • 19
    • 79960767641 scopus 로고    scopus 로고
    • Role of IL-1 a and the Nlrp3/caspase-1/ IL-1 b axis in cigarette smoke-induced pulmonary infl ammation and COPD
    • Pauwels NS, Bracke KR, Dupont LL, et al. Role of IL-1 a and the Nlrp3/caspase-1/ IL-1 b axis in cigarette smoke-induced pulmonary infl ammation and COPD. Eur Respir J. 2011; 38 ( 5): 1019-1028.
    • (2011) Eur Respir J. , vol.38 , Issue.5 , pp. 1019-1028
    • Pauwels, N.S.1    Bracke, K.R.2    Dupont, L.L.3
  • 20
    • 80052936263 scopus 로고    scopus 로고
    • Acute exacerbations of chronic obstructivepulmonary disease: Identifi cation of biologic clusters and their biomarkers
    • Bafadhel M, McKenna S, Terry S, et al. Acute exacerbations of chronic obstructivepulmonary disease: identifi cation of biologic clusters and their biomarkers. Am J Respir Crit Care Med. 2011; 184( 6): 662-671.
    • (2011) Am J Respir Crit Care Med. , vol.184 , Issue.6 , pp. 662-671
    • Bafadhel, M.1    McKenna, S.2    Terry, S.3
  • 21
    • 84876122356 scopus 로고    scopus 로고
    • Systemic infl ammation is associated with diff erential gene expression and airway neutrophilia in asthma
    • Fu JJ, Baines KJ, Wood LG, Gibson PG. Systemic infl ammation is associated with diff erential gene expression and airway neutrophilia in asthma. OMICS. 2013; 17 ( 4): 187-199.
    • (2013) OMICS. , vol.17 , Issue.4 , pp. 187-199
    • Fu, J.J.1    Baines, K.J.2    Wood, L.G.3    Gibson, P.G.4
  • 22
    • 0023092594 scopus 로고
    • A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation
    • Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987; 40 ( 5): 373-383.
    • (1987) J Chronic Dis. , vol.40 , Issue.5 , pp. 373-383
    • Charlson, M.E.1    Pompei, P.2    Ales, K.L.3    MacKenzie, C.R.4
  • 23
    • 0032724502 scopus 로고    scopus 로고
    • Development and validation of a questionnaire to measure asthma control
    • Juniper EF, O'Byrne PM, Guyatt GH, Ferrie PJ, King DR. Development and validation of a questionnaire to measure asthma control. Eur Respir J. 1999; 14 ( 4): 902-907.
    • (1999) Eur Respir J. , vol.14 , Issue.4 , pp. 902-907
    • Juniper, E.F.1    O'Byrne, P.M.2    Guyatt, G.H.3    Ferrie, P.J.4    King, D.R.5
  • 24
    • 0031847645 scopus 로고    scopus 로고
    • Epidemiological association of airway infl ammation with asthma symptoms and airway hyperresponsiveness in childhood
    • Gibson PG, Wlodarczyk JW, Hensley MJ, et al. Epidemiological association of airway infl ammation with asthma symptoms and airway hyperresponsiveness in childhood. Am J Respir Crit Care Med. 1998; 158 ( 1): 36-41.
    • (1998) Am J Respir Crit Care Med. , vol.158 , Issue.1 , pp. 36-41
    • Gibson, P.G.1    Wlodarczyk, J.W.2    Hensley, M.J.3
  • 25
    • 67649805319 scopus 로고    scopus 로고
    • An offi cial American Thoracic Society/European Respiratory Society statement: Asthma control and exacerbations: Standardizing endpoints for clinical asthma trials and clinical practice
    • American Thoracic Society/European Respiratory Society Task Force on Asthma Control and Exacerbations
    • Reddel HK, Taylor DR, Bateman ED, et al; American Thoracic Society/European Respiratory Society Task Force on Asthma Control and Exacerbations. An offi cial American Thoracic Society/European Respiratory Society statement: Asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice. Am J Respir Crit Care Med. 2009; 180 ( 1): 59-99.
    • (2009) Am J Respir Crit Care Med. , vol.180 , Issue.1 , pp. 59-99
    • Reddel, H.K.1    Taylor, D.R.2    Bateman, E.D.3
  • 26
    • 84875219719 scopus 로고    scopus 로고
    • Azithromycin for prevention of exacerbations in severe asthma (AZISAST): A multicentre randomised double-blind placebo-controlled trial
    • Brusselle GG, Vanderstichele C, Jordens P, et al. Azithromycin for prevention of exacerbations in severe asthma (AZISAST): A multicentre randomised double-blind placebo-controlled trial. Thorax. 2013; 68 ( 4): 322-329.
    • (2013) Thorax. , vol.68 , Issue.4 , pp. 322-329
    • Brusselle, G.G.1    Vanderstichele, C.2    Jordens, P.3
  • 27
    • 35148893108 scopus 로고    scopus 로고
    • Systemic effects of chronic obstructive pulmonary disease: What we know and what we don't know (but should)
    • Agustí A. Systemic effects of chronic obstructive pulmonary disease: what we know and what we don't know (but should). Proc Am Thorac Soc. 2007; 4 ( 7): 522-525.
    • (2007) Proc Am Thorac Soc. , vol.4 , Issue.7 , pp. 522-525
    • Agustí, A.1
  • 28
    • 34548577717 scopus 로고    scopus 로고
    • Introduction to structural equation modeling: Issues and practical considerations
    • Lei PW, Wu Q. Introduction to structural equation modeling: issues and practical considerations. Educ Meas Issues Pract. 2007; 26 ( 3): 33-43.
    • (2007) Educ Meas Issues Pract. , vol.26 , Issue.3 , pp. 33-43
    • Lei, P.W.1    Wu, Q.2
  • 29
    • 84861785677 scopus 로고    scopus 로고
    • Infl ammasome-regulated cytokines are critical mediators of acute lung injury
    • Dolinay T, Kim YS, Howrylak J, et al. Infl ammasome-regulated cytokines are critical mediators of acute lung injury. Am J Respir Crit Care Med. 2012; 185 ( 11): 1225-1234.
    • (2012) Am J Respir Crit Care Med. , vol.185 , Issue.11 , pp. 1225-1234
    • Dolinay, T.1    Kim, Y.S.2    Howrylak, J.3
  • 30
    • 0037202790 scopus 로고    scopus 로고
    • Asthma exacerbations and sputum eosinophil counts: A randomised controlled trial
    • Green RH, Brightling CE, McKenna S, et al. Asthma exacerbations and sputum eosinophil counts: A randomised controlled trial. Lancet. 2002; 360 ( 9347): 1715-1721.
    • (2002) Lancet. , vol.360 , Issue.9347 , pp. 1715-1721
    • Green, R.H.1    Brightling, C.E.2    McKenna, S.3
  • 31
    • 33344476409 scopus 로고    scopus 로고
    • Determining asthma treatment by monitoring sputum cell counts: Eff ect on exacerbations
    • Jayaram L, Pizzichini MM, Cook RJ, et al. Determining asthma treatment by monitoring sputum cell counts: eff ect on exacerbations. Eur Respir J. 2006; 27 ( 3): 483-494.
    • (2006) Eur Respir J. , vol.27 , Issue.3 , pp. 483-494
    • Jayaram, L.1    Pizzichini, M.M.2    Cook, R.J.3
  • 32
    • 0036165793 scopus 로고    scopus 로고
    • Eosinophilic bronchitis: Clinical manifestations and implications for treatment
    • Gibson PG, Fujimura M, Niimi A. Eosinophilic bronchitis: clinical manifestations and implications for treatment. Thorax. 2002; 57 ( 2): 178-182.
    • (2002) Thorax. , vol.57 , Issue.2 , pp. 178-182
    • Gibson, P.G.1    Fujimura, M.2    Niimi, A.3
  • 33
    • 85030376770 scopus 로고    scopus 로고
    • Global strategy for the diagnosis, management and prevention of COPD. GOLD website. Updated 2014. Accessed August 30, 2015
    • Global strategy for the diagnosis, management and prevention of COPD. GOLD website. http://www. goldcopd. com. Updated 2014. Accessed August 30, 2015.


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