Enhanced transfer of a photocross-linking N-acetylglucosamine (GlcNAc) analog by an O-GlcNAc transferase mutant with converted substrate specificity

Journal of Biological Chemistry

Volumn 290, Issue 37, 2015, Pages 22638-22648

  Rodriguez, Andrea C ^a   Yu, Seok Ho ^a   Li, Bin ^a   Zegzouti, Hicham ^b   Kohler, Jennifer J ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b PROMEGA CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELLS; CYTOLOGY; MAMMALS; PROTEINS;

COVALENTLY CROSS-LINKED; MULTICELLULAR ORGANISMS; N-ACETYLGLUCOSAMINE; PHOTOCROSS-LINKING; POST-TRANSLATIONAL MODIFICATIONS; SUBSTRATE PROTEINS; SUBSTRATE SPECIFICITY; THREONINE RESIDUES;

SUBSTRATES;

N ACETYLGLUCOSAMINE; NUCLEOPORIN; URIDINE DIPHOSPHATE; N ACETYLGLUCOSAMINYLTRANSFERASE; O-GLCNAC TRANSFERASE;

ARTICLE; CARBOHYDRATE TRANSPORT; CHEMICAL ENGINEERING; CHEMICAL MODIFICATION; CONTROLLED STUDY; COVALENT BOND; CROSS LINKING; ENZYME SPECIFICITY; IN VITRO STUDY; MUTAGENESIS; PHOTOREACTIVITY; PRIORITY JOURNAL; WILD TYPE; AMINO ACID SUBSTITUTION; GENETICS; HELA CELL LINE; HUMAN; K562 CELL LINE; METABOLISM; MISSENSE MUTATION; PHYSIOLOGY;

ACETYLGLUCOSAMINE; AMINO ACID SUBSTITUTION; HELA CELLS; HUMANS; K562 CELLS; MUTATION, MISSENSE; N-ACETYLGLUCOSAMINYLTRANSFERASES; SUBSTRATE SPECIFICITY;

EID: 84941595627     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.667006     Document Type: Article

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