Structural snapshots of the reaction coordinate for O-GlcNAc transferase

Nature Chemical Biology

Volumn 8, Issue 12, 2012, Pages 966-968

  Lazarus, Michael B ^a,b   Jiang, Jiaoyang ^b   Gloster, Tracey M ^c   Zandberg, Wesley F ^c   Whitworth, Garrett E ^c   Vocadlo, David J ^c   Walker, Suzanne ^b  

^a HARVARD UNIVERSITY   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c SIMON FRASER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BETA N ACETYLGLUCOSAMINE TRANSFERASE; N ACETYLGLUCOSAMINE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME SUBSTRATE; GLYCOSYLATION; HUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING;

EID: 84870347565     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.1109     Document Type: Article

References (25)

1. Lairson, L.L., Henrissat, B., Davies, G.J. & Withers, S.G. Annu. Rev. Biochem. 77, 521-555 (2008).
2. Torres, C.R. & Hart, G.W. J. Biol. Chem. 259, 3308-3317 (1984).
3. Kreppel, L.K., Blomberg, M.A. & Hart, G.W. J. Biol. Chem. 272, 9308-9315 (1997).
4. Sinclair, D.A. et al. Proc. Natl. Acad. Sci. USA 106, 13427-13432 (2009).
5. Love, D.C. et al. Proc. Natl. Acad. Sci. USA 107, 7413-7418 (2010).
6. Kazemi, Z., Chang, H., Haserodt, S., McKen, C. & Zachara, N.E. J. Biol. Chem. 285, 39096-39107 (2010).
7. Dentin, R., Hedrick, S., Xie, J., Yates, J. III & Montminy, M. Science 319, 1402-1405 (2008).
8. Lazarus, M.B., Nam, Y., Jiang, J., Sliz, P. & Walker, S. Nature 469, 564-567 (2011).
9. Gloster, T.M. et al. Nat. Chem. Biol. 7, 174-181 (2011).
10. Iyer, S.P. & Hart, G.W. J. Biol. Chem. 278, 24608-24616 (2003).
11. Gross, B.J., Kraybill, B.C. & Walker, S. J. Am. Chem. Soc. 127, 14588-14589 (2005).
12. Lee, S.S. et al. Nat. Chem. Biol. 7, 631-638 (2011).
13. Burkart, M.D. et al. Bioorg. Med. Chem. 8, 1937-1946 (2000).
14. Vocadlo, D.J. & Davies, G.J. Curr. Opin. Chem. Biol. 12, 539-555 (2008).
15. Schramm, V.L. & Shi, W. Curr. Opin. Struct. Biol. 11, 657-665 (2001).
16. Vocadlo, D.J., Davies, G.J., Laine, R. & Withers, S.G. Nature 412, 835-838 (2001).
17. Davies, G.J., Planas, A. & Rovira, C. Acc. Chem. Res. 45, 308-316 (2012).
18. Martinez-Fleites, C. et al. Nat. Struct. Mol. Biol. 15, 764-765 (2008).
19. Dorfmueller, H.C. et al. Amino Acids 40, 781-792 (2011).
20. Errey, J.C. et al. Angew. Chem. Int. Edn Engl. 49, 1234-1237 (2010).
21. Reinert, D.J., Jank, T., Aktories, K. & Schulz, G.E. J. Mol. Biol. 351, 973-981 (2005).
22. Shen, D.L., Gloster, T.M., Yuzwa, S.A. & Vocadlo, D.J. J. Biol. Chem. 287, 15395-15408 (2012).
23. Ramakrishnan, B., Ramasamy, V. & Qasba, P.K. J. Mol. Biol. 357, 1619-1633 (2006).
24. Persson, K. et al. Nat. Struct. Biol. 8, 166-175 (2001).
25. Ni, L. et al. Biochemistry 46, 6288-6298 (2007).