Development of curcumin loaded sodium hyaluronate immobilized vesicles (hyalurosomes) and their potential on skin inflammation and wound restoring

Biomaterials

Volumn 71, Issue , 2015, Pages 100-109

  Manca, M L ^a   Castangia, I ^a   Zaru, M ^d   Nacher A ^b,c   Valenti, D ^a   Fernandez Busquets X ^e,f,g   Fadda, A M ^a   Manconi, M ^a  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b Icnoderm Srl   (Italy)

^c UNIVERSITY OF VALENCIA   (Spain)

^d UNIVERSITAT POLITÈCNICA DE VALÈNCIA   (Spain)

^e INSTITUTE FOR BIOENGINEERING OF CATALONIA IBEC   (Spain)

^f HOSPITAL CLÍNIC   (Spain)

^g UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Cell oxidative stress; Hyaluronic acid Hyaluronan; Phospholipid vesicles; Polyphenols; Skin inflammation; Wound healing

Indexed keywords

BIOCOMPATIBILITY; CELL PROLIFERATION; HIGH RESOLUTION TRANSMISSION ELECTRON MICROSCOPY; HYALURONIC ACID; LIPOSOMES; PATHOLOGY; PHOSPHOLIPIDS; POLYMER BLENDS; SODIUM; TISSUE REGENERATION; X RAY SCATTERING;

CELLULAR PROLIFERATIONS; COMMERCIAL MIXTURES; CRYOGENIC TRANSMISSION ELECTRON MICROSCOPY; HUMAN KERATINOCYTES; PHARMACEUTICAL APPLICATIONS; PHOSPHOLIPID VESICLES; POLYPHENOLS; WOUND HEALING;

DRUG DELIVERY;

CURCUMIN; HYALURONIC ACID; HYALUROSOME; LIPOSOME; MYELOPEROXIDASE; NANOCARRIER; PHORBOL MYRISTATE; PHOSPHOLIPID; POLYMER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BIOCOMPATIBILITY; CELL MIGRATION; CELL PROLIFERATION; CHEMICAL COMPOSITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DERMATITIS; DRUG ACCUMULATION; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG EFFICACY; DRUG FORMULATION; DRUG SAFETY; DRUG SYNTHESIS; ENZYME INHIBITION; EPITHELIZATION; FEMALE; HUMAN; HUMAN CELL; IMMOBILIZATION; IN VITRO STUDY; IN VIVO STUDY; KERATINOCYTE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SKIN EDEMA; SKIN INJURY; TISSUE REGENERATION; TRANSMISSION ELECTRON MICROSCOPY; WOUND HEALING; X RAY CRYSTALLOGRAPHY; ANIMAL; CELL CULTURE; CHEMISTRY; DRUG EFFECTS; PIG; SKIN;

ANIMALS; CELLS, CULTURED; CURCUMIN; DERMATITIS; HUMANS; HYALURONIC ACID; MICROSCOPY, ELECTRON, TRANSMISSION; SKIN; SWINE; WOUND HEALING;

EID: 84941550877     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2015.08.034     Document Type: Article

References (36)

1. Sinico C., Fadda A.M. Vesicular carriers for dermal drug delivery. Expert Opin. Drug Deliv. 2009, 6:813-825. 10.1517/17425240903071029.
2. Muzzalupo R., Tavano L., Cassano R., Trombino S., Ferrarelli T., Picci N. A new approach for the evaluation of niosomes as effective transdermal drug delivery systems. Eur. J. Pharm. Biopharm. 2011, 79:28-35. 10.1016/j.ejpb.2011.01.020.
3. ® containing linoleic acid: physicochemical and technological features of topical drug delivery carriers for the potential treatment of melasma disorders. Biomed. Microdevices 2012, 14:119-130. 10.1007/s10544-011-9590-y.
4. Paolino D., Cosco D., Cilurzo F., Trapasso E., Morittu V.M., Celia C., et al. Improved in vitro and in vivo collagen biosynthesis by asiaticoside-loaded ultradeformable vesicles. J. Control Release 2012, 162:143-151. http://dx.doi.org/10.1016/j.jconrel.2012.05.050.
5. Manca M.L., Zaru M., Manconi M., Lai F., Valenti D., Sinico C., et al. Glycerosomes: a new tool for effective dermal and transdermal drug delivery. Int. J. Pharm. 2013, 455:66-74. http://dx.doi.org/10.1016/j.ijpharm.2013.07.060.
6. Castangia I., Nácher A., Caddeo C., Valenti D., Fadda A.M., Díez-Sales O., et al. Fabrication of quercetin and curcumin bionanovesicles for the prevention and rapid regeneration of full-thickness skin defects on mice. Acta Biomater. 2014, 10:1292-1300. 10.1016/j.actbio.2013.11.005.
7. Caddeo C., Díez-Sales O., Pons R., Fernàndez-Busquets X., Fadda A., Manconi M. Topical anti-inflammatory potential of quercetin in lipid-based nanosystems: in vivo and in vitro evaluation. Pharm. Res. 2014, 31:959-968. 10.1007/s11095-013-1215-0.
8. Manconi M., Caddeo C., Sinico C., Valenti D., Mostallino M.C., Biggio G., et al. Ex vivo skin delivery of diclofenac by transcutol containing liposomes and suggested mechanism of vesicle-skin interaction. Eur. J. Pharm. Biopharm. 2011, 78:27-35.
9. Puglia C., Trombetta D., Venuti V., Saija A., Bonina F. Evaluation of in-vivo topical anti-inflammatory activity of indometacin from liposomal vesicles. J. Pharm. Pharmacol. 2004, 56:1225-1232. 10.1211/0022357044445.
10. Elnaggar Y.S.R., El-Refaie W.M., El-Massik M.A., Abdallah O.Y. Lecithin-based nanostructured gels for skin delivery: an update on state of art and recent applications. J. Control Release 2014, 180:10-24. 10.1016/j.jconrel.2014.02.004.
11. Pavelić Ž., Škalko-Basnet N., Schubert R. Liposomal gels for vaginal drug delivery. Int. J. Pharm. 2001, 219:139-149. 10.1016/S0378-5173(01)00637-8.
12. Manca M.L., Manconi M., Falchi A.M., Castangia I., Valenti D., Lampis S., et al. Close-packed vesicles for diclofenac skin delivery and fibroblast targeting. Colloids Surfaces B Biointerfaces 2013, 111:609-617. http://dx.doi.org/10.1016/j.colsurfb.2013.07.014.
13. Tiwari S., Goyal A.K., Mishra N., Khatri K., Vaidya B., Mehta A., et al. Development and characterization of novel carrier gel core liposomes based transmission blocking malaria vaccine. J. Control Release 2009, 140:157-165. 10.1016/j.jconrel.2009.08.004.
14. Manca Maria Letizia, Manconi Maria, Zaru Marco, Castangia Ines, Cabras Alba, Cappai Nadia, Fadda A.M. Ialurosomi, loro uso in composizioni topiche farmaceutiche o cosmetiche e relativo procedimento di preparazione 2014, RM2014A000687.
15. Kim S.J., Hahn S.K., Kim M.J., Kim D.H., Lee Y.P. Development of a novel sustained release formulation of recombinant human growth hormone using sodium hyaluronate microparticles. J. Control Release 2005, 104:323-335. 10.1016/j.jconrel.2005.02.012.
16. Chen W.Y.J., Abatangelo G. Functions of hyaluronan in wound repair. Wound Repair Regen. 1999, 7:79-89. 10.1046/j.1524-475X.1999.00079.x.
17. Bar-Sela G., Epelbaum R., Shaffer M. Curcumin as an anti-cancer agent: review of the gap between basic and clinical applications | BenthamScience. Curr. Med. Chem. 2010, 17.
18. Jurenka J.S. Anti-inflammatory properties of curcumin, a major constituent of curcuma longa: a review of preclinical and clinical research. Altern. Med. Rev. 2009, 14:141-153.
19. Strimpakos A.S., Sharma R.A. Curcumin: preventive and therapeutic properties in laboratory studies and clinical trials. Antioxid. Redox Signal 2008, 10:511-546.
20. Aggarwal Paabkran B.B. Bioavailability of curcumin: problems and promises. Mol. Pharm. 2007, 807-818. (accessed 09.03.15.). http://pubs.acs.org/doi/pdf/10.1021/mp700113r.
21. Stewart J.C.M. Colorimetric determination of phospholipids with ammonium ferrothiocyanate. Anal. Biochem. 1980, 104:10-14. http://dx.doi.org/10.1016/0003-2697(80)90269-9.
22. Pabst G., Rappolt M., Amenitsch H., Laggner P. Structural information from multilamellar liposomes at full hydration: full q-range fitting with high quality x-ray data. Phys. Rev. E 2000, 62:4000-4009.
23. Manca M.L., Castangia I., Caddeo C., Pando D., Escribano E., Valenti D., et al. Improvement of quercetin protective effect against oxidative stress skin damages by incorporation in nanovesicles. Colloids Surf. B Biointerfaces 2014, 123:566-574. 10.1016/j.colsurfb.2014.09.059.
24. Manca M.L., Castangia I., Matricardi P., Lampis S., Fernàndez-Busquets X., Fadda A.M., et al. Molecular arrangements and interconnected bilayer formation induced by alcohol or polyalcohol in phospholipid vesicles. Colloids Surf. B Biointerfaces 2014, 117:360-367. 10.1016/j.colsurfb.2014.03.010.
25. Youssry M., Coppola L., Nicotera I., Morán C. Swollen and collapsed lyotropic lamellar rheology. J. Colloid Interface Sci. 2008, 321:459-467. 10.1016/j.jcis.2008.02.023.
26. Sandolo C., Matricardi P., Alhaique F., Coviello T. Effect of temperature and cross-linking density on rheology of chemical cross-linked guar gum at the gel point. Food Hydrocoll. 2009, 23:210-220. 10.1016/j.foodhyd.2008.01.001.
27. Krausz A.E., Adler B.L., Cabral V., Navati M., Doerner J., Charafeddine R.A., et al. Curcumin-encapsulated nanoparticles as innovative antimicrobial and wound healing agent. Nanomedicine 2015, 11:195-206. 10.1016/j.nano.2014.09.004.
28. Li X., Chen S., Zhang B., Li M., Diao K., Zhang Z., et al. In situ injectable nano-composite hydrogel composed of curcumin, N,O-carboxymethyl chitosan and oxidized alginate for wound healing application. Int. J. Pharm. 2012, 437:110-119. 10.1016/j.ijpharm.2012.08.001.
29. Gong C., Wu Q., Wang Y., Zhang D., Luo F., Zhao X., et al. A biodegradable hydrogel system containing curcumin encapsulated in micelles for cutaneous wound healing. Biomaterials 2013, 34:6377-6387. 10.1016/j.biomaterials.2013.05.005.
30. Li X., Nan K., Li L., Zhang Z., Chen H. In vivo evaluation of curcumin nanoformulation loaded methoxy poly(ethylene glycol)-graft-chitosan composite film for wound healing application. Carbohydr. Polym. 2012, 88:84-90. 10.1016/j.carbpol.2011.11.068.
31. Abramović Z., Sustarsic U., Teskac K., Sentjurc M., Kristl J. Influence of nanosized delivery systems with benzyl nicotinate and penetration enhancers on skin oxygenation. Int. J. Pharm. 2008, 359:220-227. 10.1016/j.ijpharm.2008.03.014.
32. Scherer P.G., Seelig J. Electric charge effects on phospholipid headgroups. Phosphatidylcholine in mixtures with cationic and anionic amphiphiles. Biochemistry 1989, 28:7720-7728. 10.1021/bi00445a030.
33. Gopinath D., Ahmed M.R., Gomathi K., Chitra K., Sehgal P.K., Jayakumar R. Dermal wound healing processes with curcumin incorporated collagen films. Biomaterials 2004, 25:1911-1917. http://dx.doi.org/10.1016/S0142-9612(03)00625-2.
34. Kong M., Chen X.G., Kweon D.K., Park H.J. Investigations on skin permeation of hyaluronic acid based nanoemulsion as transdermal carrier. Carbohydr. Polym. 2011, 86:837-843. 10.1016/j.carbpol.2011.05.027.
35. Brown M.B., Jones S.A. Hyaluronic acid: a unique topical vehicle for the localized delivery of drugs to the skin. J. Eur. Acad. Dermatol. Venereol. 2005, 19:308-318. 10.1111/j.1468-3083.2004.01180.x.
36. Manuskiatti W., Maibach H.I. Hyaluronic acid and skin: wound healing and aging. Int. J. Dermatol. 1996, 35:539-544. 10.1111/j.1365-4362.1996.tb03650.x.