Fabrication of quercetin and curcumin bionanovesicles for the prevention and rapid regeneration of full-thickness skin defects on mice

Acta Biomaterialia

Volumn 10, Issue 3, 2014, Pages 1292-1300

  Castangia, Ines ^a   Nácher, Amparo ^b,c   Caddeo, Carla ^a   Valenti, Donatella ^a   Fadda, Anna Maria ^a   Díez Sales, Octavio ^b,c   Ruiz Saurí, Amparo ^b   Manconi, Maria ^a  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b UNIVERSITY OF VALENCIA   (Spain)

^c UNIVERSITAT POLITÈCNICA DE VALÈNCIA   (Spain)

Author keywords

Histopathology; Polyphenols; Skin inflammation; Vesicles; Wound healing

Indexed keywords

BIOCOMPATIBILITY; DERMATOLOGY; FLAVONOIDS; HIGH RESOLUTION TRANSMISSION ELECTRON MICROSCOPY; LIPOSOMES; PHENOLS; PHOSPHOLIPIDS; POLYETHYLENE GLYCOLS; POLYETHYLENES; PROBES; X RAY SCATTERING;

CURCUMIN; HISTOPATHOLOGY; NANOVESICLE; PENETRATION ENHANCERS; POLYPHENOLS; RAPID REGENERATION; SKIN INFLAMMATION; TETRADECANOYLPHORBOL 13 ACETATES; VESICLE; WOUND HEALING;

PATHOLOGY;

CURCUMIN; LIPOSOME; MACROGOL; MACROGOL 400; MYELOPEROXIDASE; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHOLIPID; QUERCETIN; WATER; NANOPARTICLE; PEROXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; MOUSE; NANOFABRICATION; NONHUMAN; PRIORITY JOURNAL; RADIATION SCATTERING; REGENERATION; SKIN DEFECT; SKIN PENETRATION; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; CHEMISTRY; DISEASE MODEL; DRUG EFFECTS; EDEMA; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; PARTICLE SIZE; PATHOLOGY; PIG; SKIN; SMALL ANGLE SCATTERING; STATIC ELECTRICITY; ULTRASTRUCTURE; X RAY DIFFRACTION;

MUS;

ANIMALS; CURCUMIN; DISEASE MODELS, ANIMAL; EDEMA; FEMALE; LIPOSOMES; MICE; MICE, INBRED ICR; NANOPARTICLES; PARTICLE SIZE; PEROXIDASE; QUERCETIN; REGENERATION; SCATTERING, SMALL ANGLE; SKIN; STATIC ELECTRICITY; SUS SCROFA; X-RAY DIFFRACTION;

EID: 84895068961     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2013.11.005     Document Type: Article

References (38)

1. J.K. Prasain, and S. Barnes Metabolism and bioavailability of flavonoids in chemoprevention: current analytical strategies and future prospectus Mol Pharm 4 2007 846 864
2. T.-T. Phan, P. See, S.-T. Lee, and S.-Y. Chan Protective effects of curcumin against oxidative damage on skin cells in vitro: its implication for wound healing J Trauma Acute Care Surg 51 2001 927 931
3. M. Panchatcharam, S. Miriyala, V. Gayathri, and L. Suguna Curcumin improves wound healing by modulating collagen and decreasing reactive oxygen species Mol Cell Biochem 290 2006 87 96
4. I. Appleton Wound healing: future directions IDrugs 6 2003 1067 1072
5. J.A. Nichols, and S.K. Kativar Skin photoprotection by natural polyphenols: anti-inflammatory, antioxidant and DNA repair mechanisms 2010 Springer Heidelberg
6. M.M. Yallapu, M. Jaggi, and S.C. Chauhan Curcumin nanoformulations: a future nanomedicine for cancer Drug Discovery Today 17 2012 71 80
7. C. Caddeo, M. Manconi, A.M. Fadda, F. Lai, S. Lampis, and O. Diez-Sales et al. Nanocarriers for antioxidant resveratrol: formulation approach, vesicle self-assembly and stability evaluation Colloids Surf B 111 2013 327 332
8. M. Chessa, C. Caddeo, D. Valenti, M. Manconi, C. Sinico, and A.M. Fadda Effect of penetration enhancer containing vesicles on the percutaneous delivery of quercetin through new born pig skin Pharmaceutics 3 2011 497 509
9. D. Pando, C. Caddeo, M. Manconi, A.M. Fadda, and C. Pazos Nanodesign of olein vesicles for the topical delivery of the antioxidant resveratrol J Pharm Pharmacol 65 2013 1158 1167
10. C. Mohanty, M. Das, and S.K. Sahoo Sustained Wound healing activity of curcumin loaded oleic acid based polymeric bandage in a rat model Mol Pharm 9 2012 2801 2811
11. K. Gomathi, D. Gopinath, M. Rafiuddin Ahmed, and R. Jayakumar Quercetin incorporated collagen matrices for dermal wound healing processes in rat Biomaterials 24 2003 2767 2772
12. D. Gopinath, M.R. Ahmed, K. Gomathi, K. Chitra, P.K. Sehgal, and R. Jayakumar Dermal wound healing processes with curcumin incorporated collagen films Biomaterials 25 2004 1911 1917
13. I.P. Süntar, E.K. Akkol, F.N. YalçIn, U. Koca, H. Keleş, and E. Yesilada Wound healing potential of Sambucus ebulus L. leaves and isolation of an active component, quercetin 3-O-glucoside J Ethnopharmacol 129 2010 106 114
14. A. Martin The use of antioxidants in healing Dermatol Surg 22 1996 156 160
15. C. Caddeo, O.D. Sales, D. Valenti, A.R. Saurí, A.M. Fadda, and M. Manconi Inhibition of skin inflammation in mice by diclofenac in vesicular carriers: liposomes, ethosomes and PEVs Int J Pharm 443 2013 128 136
16. M. Manconi, J. Aparicio, A.O. Vila, J. Pendàs, J. Figueruelo, and F. Molina Viscoelastic properties of concentrated dispersions in water of soy lecithin Colloids Surf A 222 2003 141 145
17. J.C.M. Stewart Colorimetric determination of phospholipids with ammonium ferrothiocyanate Anal Biochem 104 1980 10 14
18. G. Pabst, M. Rappolt, H. Amenitsch, and P. Laggner Structural information from multilamellar liposomes at full hydration: full q-range fitting with high quality X-ray data Phys Rev E 62 2000 4000 4009
19. H. Sato, I. Sugimoto, T. Matsunaga, M. Tsuchimoto, T. Ohta, and H. Uno et al. Tacalcitol (1,24(OH)2D3, TV-02) inhibits phorbol ester-induced epidermal proliferation and cutaneous inflammation, and induces epidermal differentiation in mice Arch Dermatol Res 288 1996 656 663
20. R.H. Liu Health benefits of fruit and vegetables are from additive and synergistic combinations of phytochemicals Am J Clin Nutr 78 2003 517S 520S
21. J.M. Davis, E.A. Murphy, and M.D. Carmichael Effects of the dietary flavonoid quercetin upon performance and health Curr Sports Med Rep 8 2009 206 213
22. A. Martin The use of antioxidants in healing 1996 Wiley Malden, MA
23. G.S. Sidhu, A.K. Singh, D. Thaloor, K.K. Banaudha, G.K. Patnaik, and R.C. Srimal et al. Enhancement of wound healing by curcumin in animals Wound Repair Regen 6 1998 167 177
24. M. Manconi, F. Marongiu, G. Ennas, A. Scano, C. Sinico, and D. Valenti et al. Liposomes for (trans)dermal delivery of tretinoin: influence of drug concentration and vesicle composition J Drug Deliv Sci Technol 18 2008 309 313
25. C.H. Purdon, C.G. Azzi, J. Zhang, E.W. Smith, and H.I. Maibach Penetration enhancement of transdermal delivery-current permutations and limitations Crit Rev Ther Drug Carrier Syst 21 2004 97 132
26. M. Manconi, C. Sinico, C. Caddeo, A.O. Vila, D. Valenti, and A.M. Fadda Penetration enhancer containing vesicles as carriers for dermal delivery of tretinoin Int J Pharm 412 2011 37 46
27. M. Manconi, S. Mura, C. Sinico, A.M. Fadda, A.O. Vila, and F. Molina Development and characterization of liposomes containing glycols as carriers for diclofenac Colloids Surf A 342 2009 53 58
28. S.H. Moghadam, E. Saliaj, S.D. Wettig, C. Dong, M.V. Ivanova, and J.T. Huzil et al. Effect of chemical permeation enhancers on stratum corneum barrier lipid organizational structure and interferon alpha permeability Mol Pharm 10 2013 2248 2260
29. W.-C. Hung, F.-Y. Chen, C.-C. Lee, Y. Sun, M.-T. Lee, and H.W. Huang Membrane-thinning effect of curcumin Biophys J 94 2008 4331 4338
30. Z. Abramovic, U. Sustarsic, K. Teskac, M. Sentjurc, and J. Kristl Influence of nanosized delivery systems with benzyl nicotinate and penetration enhancers on skin oxygenation Int J Pharm 359 2008 220 227
31. A.D. Petelska, and Z.A. Figaszewski Interfacial tension of phosphatidylcholine-phosphatidylserine system in bilayer lipid membrane Biophys Chem 120 2006 199 206
32. H.F. Frasch, and A.M. Barbero A paired comparison between human skin and hairless guinea pig skin in vitro permeability and lag time measurements for 6 industrial chemicals Cutan Ocul Toxicol 28 2009 107 113
33. F. Cilurzo, P. Minghetti, and C. Sinico Newborn pig skin as model membrane in in vitro drug permeation studies: a technical note AAPS PharmSciTech 8 2007 97 100
34. Y. Liu, J.Y. Chen, H.T. Shang, C.E. Liu, Y. Wang, and R. Niu et al. Light microscopic, electron microscopic, and immunohistochemical comparison of Bama minipig (Sus scrofa domestica) and human skin Comp Med 60 2010 142 148
35. M. Manconi, C. Caddeo, C. Sinico, D. Valenti, M.C. Mostallino, and G. Biggio et al. Ex vivo skin delivery of diclofenac by transcutol containing liposomes and suggested mechanism of vesicle-skin interaction Eur J Pharm Biopharm 78 2011 27 35
36. S.M. San Miguel, L.A. Opperman, E.P. Allen, J. Zielinski, and K.K.H. Svoboda Bioactive polyphenol antioxidants protect oral fibroblasts from ROS-inducing agents Arch Oral Biol 57 2012 1657 1667
37. S.J. Kim, M.H. Lim, I.K. Chun, and Y.H. Won Effects of flavonoids of Ginkgo biloba on proliferation of human skin fibroblast Skin Pharmacol Physiol 10 1997 200 205
38. R.K. Maheshwari, A.K. Singh, J. Gaddipati, and R.C. Srimal Multiple biological activities of curcumin: a short review Life Sci 78 2006 2081 2087