Multiscale impact of nucleotides and cations on the conformational equilibrium, elasticity and rheology of actin filaments and crosslinked networks

Biomechanics and Modeling in Mechanobiology

Volumn 14, Issue 5, 2015, Pages 1143-1155

  Bidone, Tamara Carla ^a,b   Kim, Taeyoon ^c   Deriu, Marco A ^d   Morbiducci, Umberto ^a   Kamm, Roger D ^e  

^a POLITECNICO DI TORINO   (Italy)

^b LEHIGH UNIVERSITY   (United States)

^c PURDUE UNIVERSITY   (United States)

^d UNIVERSITY OF APPLIED SCIENCES AND ARTS OF SOUTHERN SWITZERLAND   (Switzerland)

^e MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Actin filament; Cation; Multiscale model; Network; Rheology

Indexed keywords

BINDING SITES; COMPUTATIONAL CHEMISTRY; COMPUTATIONAL METHODS; CONFORMATIONS; ELASTICITY; MOLECULAR DYNAMICS; MONOMERS; POSITIVE IONS; PROTEINS; RHEOLOGY; RIGIDITY; SCAFFOLDS (BIOLOGY); SELF ASSEMBLY;

ACTIN CYTOSKELETON; ACTIN FILAMENT; ACTIN NETWORKS; CATION BINDING; F-ACTIN; MOLECULAR CHANGES; MULTISCALE MODELING; NETWORK; RHEOLOGICAL BEHAVIOUR; STRAIN STIFFENING;

NUCLEOTIDES;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CALCIUM ION; CATION; F ACTIN; MAGNESIUM; NUCLEOTIDE; ACTIN; CROSS LINKING REAGENT;

ACTIN FILAMENT; ARTICLE; CHEMICAL BINDING; CHEMICAL INTERACTION; CONFORMATION; CROSS LINKING; ELASTICITY; FLOW KINETICS; MOLECULAR DYNAMICS; PRIORITY JOURNAL; RIGIDITY; STRETCHING; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; FRICTION; MECHANICAL STRESS; MECHANOTRANSDUCTION; PROTEIN CONFORMATION; ULTRASTRUCTURE; VISCOSITY; YOUNG MODULUS;

ACTIN CYTOSKELETON; ACTINS; CATIONS; COMPUTER SIMULATION; CROSS-LINKING REAGENTS; ELASTIC MODULUS; FRICTION; MECHANOTRANSDUCTION, CELLULAR; MODELS, CHEMICAL; MODELS, MOLECULAR; NUCLEOTIDES; PROTEIN CONFORMATION; STRESS, MECHANICAL; VISCOSITY;

EID: 84941317541     PISSN: 16177959     EISSN: 16177940     Source Type: Journal    
DOI: 10.1007/s10237-015-0660-6     Document Type: Article

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